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The map label for this gene is ilvE [H]

Identifier: 150401618

GI number: 150401618

Start: 1262222

End: 1263082

Strand: Direct

Name: ilvE [H]

Synonym: Maeo_1195

Alternate gene names: 150401618

Gene position: 1262222-1263082 (Clockwise)

Preceding gene: 150401617

Following gene: 150401619

Centisome position: 80.42

GC content: 32.75

Gene sequence:

>861_bases
ATGAAAATATATTTAAATGGCGAATTTGTCGAAAAAGAACAGGCAAAAATTTCAGTTTATGATCACGGTTTATTATATGG
AGATGGAGTATTTGAAGGAATTAGGGTATATGATGGGGTAATATTCAAGTTAAAGGAACATATAGATAGATTATTCGATT
CTGCAACTTCTCTTCAAATGGACATACAAACATCAAAAGATGAAATATCAAAAATCGTAATTGATACAATTAGAATAAAT
GAATTAAATAATGCATATATTAGATTGGTAATTACAAGGGGAGTTGGGGATTTGGGATTAGACCCTAGAAAATGTCCAAA
ACCGACCATTTTTTGTATTGCCGAACCTATGAATCCATTGCTCGGCGAAGATGGCATAAAAGTAATTACTTCTTCAATTA
GAAGGTTACCTGTTGATGTTTTAAATCCTGCTGTAAAATCATTAAATTATTTAAACAGTATATTGGCAAAAATTCAGGCA
AATTATGCCGGATGTGATGAGGCATTTTTATTGGATAGCGAGGGCTATGTGGCCGAAGGAACCGGGGACAATATATTTGT
AATAAAAAATGGAAAAATAAAAACCCCTCCTGTGTCTTCCAGTGTTTTAAAAGGAATTACAAGAGATGCCGTAGTTGATT
TGGCAAAAGAACAAGGATATGAAATTATAGAGGAGAAATTAACTCTCCACGATTTATATGTTGCCGACGAGTTATTTATC
ACTGGAACAGCTGCGGAATTAGCTCATGTTGTTGAAATAGATGGAAGAGTTATAAACAACAGGGAAATGGGAGTAATTAC
AAAAAAGTTGAGTGAGGAATTTAAGAAAATAAGAAAGATTATGGGGACAAAAGTTTATTAA

Upstream 100 bases:

>100_bases
ATAGAACAAACTTCTGAATATACTATAAAAATAGAAACTTATTTATTTTAATAGGTGTTATTTTAATAAAAAATATCATT
TCAAAATTTGAGGTGTCATT

Downstream 100 bases:

>100_bases
TAATTTTTTTATTGTTTTTTTAATTTTTTAACCTACGAAATTTATTTTTTTATTTTTATTATAATATTTTAATTTATTAA
TTATCAATTATTTATTAATT

Product: branched-chain amino acid aminotransferase

Products: NA

Alternate protein names: BCAT; Transaminase B [H]

Number of amino acids: Translated: 286; Mature: 286

Protein sequence:

>286_residues
MKIYLNGEFVEKEQAKISVYDHGLLYGDGVFEGIRVYDGVIFKLKEHIDRLFDSATSLQMDIQTSKDEISKIVIDTIRIN
ELNNAYIRLVITRGVGDLGLDPRKCPKPTIFCIAEPMNPLLGEDGIKVITSSIRRLPVDVLNPAVKSLNYLNSILAKIQA
NYAGCDEAFLLDSEGYVAEGTGDNIFVIKNGKIKTPPVSSSVLKGITRDAVVDLAKEQGYEIIEEKLTLHDLYVADELFI
TGTAAELAHVVEIDGRVINNREMGVITKKLSEEFKKIRKIMGTKVY

Sequences:

>Translated_286_residues
MKIYLNGEFVEKEQAKISVYDHGLLYGDGVFEGIRVYDGVIFKLKEHIDRLFDSATSLQMDIQTSKDEISKIVIDTIRIN
ELNNAYIRLVITRGVGDLGLDPRKCPKPTIFCIAEPMNPLLGEDGIKVITSSIRRLPVDVLNPAVKSLNYLNSILAKIQA
NYAGCDEAFLLDSEGYVAEGTGDNIFVIKNGKIKTPPVSSSVLKGITRDAVVDLAKEQGYEIIEEKLTLHDLYVADELFI
TGTAAELAHVVEIDGRVINNREMGVITKKLSEEFKKIRKIMGTKVY
>Mature_286_residues
MKIYLNGEFVEKEQAKISVYDHGLLYGDGVFEGIRVYDGVIFKLKEHIDRLFDSATSLQMDIQTSKDEISKIVIDTIRIN
ELNNAYIRLVITRGVGDLGLDPRKCPKPTIFCIAEPMNPLLGEDGIKVITSSIRRLPVDVLNPAVKSLNYLNSILAKIQA
NYAGCDEAFLLDSEGYVAEGTGDNIFVIKNGKIKTPPVSSSVLKGITRDAVVDLAKEQGYEIIEEKLTLHDLYVADELFI
TGTAAELAHVVEIDGRVINNREMGVITKKLSEEFKKIRKIMGTKVY

Specific function: Acts on leucine, isoleucine and valine [H]

COG id: COG0115

COG function: function code EH; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Escherichia coli, GI48994963, Length=281, Percent_Identity=40.9252669039146, Blast_Score=207, Evalue=7e-55,
Organism=Escherichia coli, GI1787338, Length=234, Percent_Identity=29.4871794871795, Blast_Score=93, Evalue=2e-20,

Paralogues:

None

Copy number: 2342 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 11,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001544
- InterPro:   IPR018300
- InterPro:   IPR005785 [H]

Pfam domain/function: PF01063 Aminotran_4 [H]

EC number: =2.6.1.42 [H]

Molecular weight: Translated: 31825; Mature: 31825

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: PS00770 AA_TRANSFER_CLASS_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIYLNGEFVEKEQAKISVYDHGLLYGDGVFEGIRVYDGVIFKLKEHIDRLFDSATSLQM
CEEEECCCEECCCCCEEEEEECCEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHEEE
DIQTSKDEISKIVIDTIRINELNNAYIRLVITRGVGDLGLDPRKCPKPTIFCIAEPMNPL
EEECCHHHHHHHHHHEEEEECCCCEEEEEEEECCCCCCCCCCCCCCCCEEEEEECCCCCC
LGEDGIKVITSSIRRLPVDVLNPAVKSLNYLNSILAKIQANYAGCDEAFLLDSEGYVAEG
CCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCEEEEC
TGDNIFVIKNGKIKTPPVSSSVLKGITRDAVVDLAKEQGYEIIEEKLTLHDLYVADELFI
CCCEEEEEECCEECCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHEEECEEEE
TGTAAELAHVVEIDGRVINNREMGVITKKLSEEFKKIRKIMGTKVY
EECHHHHHHHHEECCEEECCCCHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKIYLNGEFVEKEQAKISVYDHGLLYGDGVFEGIRVYDGVIFKLKEHIDRLFDSATSLQM
CEEEECCCEECCCCCEEEEEECCEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHEEE
DIQTSKDEISKIVIDTIRINELNNAYIRLVITRGVGDLGLDPRKCPKPTIFCIAEPMNPL
EEECCHHHHHHHHHHEEEEECCCCEEEEEEEECCCCCCCCCCCCCCCCEEEEEECCCCCC
LGEDGIKVITSSIRRLPVDVLNPAVKSLNYLNSILAKIQANYAGCDEAFLLDSEGYVAEG
CCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCEEEEC
TGDNIFVIKNGKIKTPPVSSSVLKGITRDAVVDLAKEQGYEIIEEKLTLHDLYVADELFI
CCCEEEEEECCEECCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHEEECEEEE
TGTAAELAHVVEIDGRVINNREMGVITKKLSEEFKKIRKIMGTKVY
EECHHHHHHHHEECCEEECCCCHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]