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The map label for this gene is rio2 [H]

Identifier: 150401585

GI number: 150401585

Start: 1219623

End: 1220507

Strand: Reverse

Name: rio2 [H]

Synonym: Maeo_1162

Alternate gene names: 150401585

Gene position: 1220507-1219623 (Counterclockwise)

Preceding gene: 150401589

Following gene: 150401584

Centisome position: 77.76

GC content: 27.91

Gene sequence:

>885_bases
ATGGAATTAAATGATAATGAATGGAGAACTTTAAAAATCATAGAAATATCCATGAAACATTATGAATGGGTGCCATTATT
TGAAATAATTAAAAAAACCAAAACAAATAAAAAAGAGGCACTATATCGATTGAGAATATTGGATAAACATAAATTAATCA
ATAGGAGCTCCTATGGATACCGACTATCCCACTGGGGATATGATGCCTTGGCATTGAACACATTTATTAAAAAGGAGCTC
CTATCTGCAATAGGTGGAAAATTAGGTGTTGGAAAAGAAGGGGATGTATATAATGTAATACTCACAAATAAAAGAGAAGC
AGTGCTAAAATTCCACAATATAGGAAGAACTTGCTTTTCAATGGGGAAAAGATATAGAAGTTATTTGGCAGAAAAAAGAC
ATATTAGTTGGCTTTATGCTTCAAGATTAACGGCTCAAAAGGAATTTGAAGTATTAAATGAATTATTTCCAATTGTAAAA
GTCCCAGAACCTATCGAACAAAATAGACATGCCATAATTATGGGAAAAATAGACGGAGCGGAATTAAAAAAGGTTGATTT
AAAAAAATTAGATGTTGATATTTATAAATTATTTTGGGACATAATTGAAGAAATAAAAAAAATGTATAAATTAAATTATG
TTCATTGTGATTTAAGCGAATTTAACATATTAATTAAGGAAGATGGAGATTTTATTATAATCGACTTCCCACAGGCACTA
AATATAAATGAAGAAGGTCAAAAATTCGATAAAATACCTGGAGAATTTAGCCAAGATATAGAATTTTATTTAAAAAGAGA
TATAGGTAATATATTACGACATTTTAAAAAATACGGCATAAATGAAGATTTAAATAAAATTTATAATTACATAATTGGCG
GTTAA

Upstream 100 bases:

>100_bases
ATAAAAAACATAAAACTTAAAATAAAATAATAATAAAAAATATATAAAAAACATAAAAAATACAAAGGGTGCAAATATAG
ACAGAATAATTAACACAATT

Downstream 100 bases:

>100_bases
TCGGTGCTATGATGGATAAAAATACTAACAATATAATTATCCCACTTCTTTTAATTATTATTACAATGATGGGAGCATAT
ATATTATATGATAAATTTGG

Product: protein of unknown function RIO1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 294; Mature: 294

Protein sequence:

>294_residues
MELNDNEWRTLKIIEISMKHYEWVPLFEIIKKTKTNKKEALYRLRILDKHKLINRSSYGYRLSHWGYDALALNTFIKKEL
LSAIGGKLGVGKEGDVYNVILTNKREAVLKFHNIGRTCFSMGKRYRSYLAEKRHISWLYASRLTAQKEFEVLNELFPIVK
VPEPIEQNRHAIIMGKIDGAELKKVDLKKLDVDIYKLFWDIIEEIKKMYKLNYVHCDLSEFNILIKEDGDFIIIDFPQAL
NINEEGQKFDKIPGEFSQDIEFYLKRDIGNILRHFKKYGINEDLNKIYNYIIGG

Sequences:

>Translated_294_residues
MELNDNEWRTLKIIEISMKHYEWVPLFEIIKKTKTNKKEALYRLRILDKHKLINRSSYGYRLSHWGYDALALNTFIKKEL
LSAIGGKLGVGKEGDVYNVILTNKREAVLKFHNIGRTCFSMGKRYRSYLAEKRHISWLYASRLTAQKEFEVLNELFPIVK
VPEPIEQNRHAIIMGKIDGAELKKVDLKKLDVDIYKLFWDIIEEIKKMYKLNYVHCDLSEFNILIKEDGDFIIIDFPQAL
NINEEGQKFDKIPGEFSQDIEFYLKRDIGNILRHFKKYGINEDLNKIYNYIIGG
>Mature_294_residues
MELNDNEWRTLKIIEISMKHYEWVPLFEIIKKTKTNKKEALYRLRILDKHKLINRSSYGYRLSHWGYDALALNTFIKKEL
LSAIGGKLGVGKEGDVYNVILTNKREAVLKFHNIGRTCFSMGKRYRSYLAEKRHISWLYASRLTAQKEFEVLNELFPIVK
VPEPIEQNRHAIIMGKIDGAELKKVDLKKLDVDIYKLFWDIIEEIKKMYKLNYVHCDLSEFNILIKEDGDFIIIDFPQAL
NINEEGQKFDKIPGEFSQDIEFYLKRDIGNILRHFKKYGINEDLNKIYNYIIGG

Specific function: Unknown

COG id: COG0478

COG function: function code T; RIO-like serine/threonine protein kinase fused to N-terminal HTH domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

Organism=Homo sapiens, GI229331971, Length=283, Percent_Identity=33.5689045936396, Blast_Score=151, Evalue=8e-37,
Organism=Homo sapiens, GI229331967, Length=283, Percent_Identity=33.5689045936396, Blast_Score=150, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI32564178, Length=283, Percent_Identity=32.5088339222615, Blast_Score=141, Evalue=4e-34,
Organism=Saccharomyces cerevisiae, GI6324122, Length=290, Percent_Identity=32.0689655172414, Blast_Score=153, Evalue=3e-38,
Organism=Drosophila melanogaster, GI24649986, Length=301, Percent_Identity=32.5581395348837, Blast_Score=149, Evalue=3e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011009
- InterPro:   IPR000719
- InterPro:   IPR018934
- InterPro:   IPR015285
- InterPro:   IPR000687
- InterPro:   IPR018935 [H]

Pfam domain/function: PF01163 RIO1; PF09202 Rio2_N [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 34748; Mature: 34748

Theoretical pI: Translated: 9.44; Mature: 9.44

Prosite motif: PS00109 PROTEIN_KINASE_TYR ; PS50011 PROTEIN_KINASE_DOM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELNDNEWRTLKIIEISMKHYEWVPLFEIIKKTKTNKKEALYRLRILDKHKLINRSSYGY
CCCCCCCCEEEEEEEEEHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCE
RLSHWGYDALALNTFIKKELLSAIGGKLGVGKEGDVYNVILTNKREAVLKFHNIGRTCFS
EECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCHHHHHHHHHCCHHHHH
MGKRYRSYLAEKRHISWLYASRLTAQKEFEVLNELFPIVKVPEPIEQNRHAIIMGKIDGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCEEEEEECCCC
ELKKVDLKKLDVDIYKLFWDIIEEIKKMYKLNYVHCDLSEFNILIKEDGDFIIIDFPQAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECHHHCEEEEEECCCEEEEECCCCC
NINEEGQKFDKIPGEFSQDIEFYLKRDIGNILRHFKKYGINEDLNKIYNYIIGG
CCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MELNDNEWRTLKIIEISMKHYEWVPLFEIIKKTKTNKKEALYRLRILDKHKLINRSSYGY
CCCCCCCCEEEEEEEEEHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCE
RLSHWGYDALALNTFIKKELLSAIGGKLGVGKEGDVYNVILTNKREAVLKFHNIGRTCFS
EECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCHHHHHHHHHCCHHHHH
MGKRYRSYLAEKRHISWLYASRLTAQKEFEVLNELFPIVKVPEPIEQNRHAIIMGKIDGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCEEEEEECCCC
ELKKVDLKKLDVDIYKLFWDIIEEIKKMYKLNYVHCDLSEFNILIKEDGDFIIIDFPQAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECHHHCEEEEEECCCEEEEECCCCC
NINEEGQKFDKIPGEFSQDIEFYLKRDIGNILRHFKKYGINEDLNKIYNYIIGG
CCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]