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The map label for this gene is truD [H]

Identifier: 150401583

GI number: 150401583

Start: 1217750

End: 1218949

Strand: Direct

Name: truD [H]

Synonym: Maeo_1160

Alternate gene names: 150401583

Gene position: 1217750-1218949 (Clockwise)

Preceding gene: 150401582

Following gene: 150401586

Centisome position: 77.59

GC content: 22.67

Gene sequence:

>1200_bases
ATGAAATTAAGGCAAACTAATGGCGATTTCATTGTAAATGAGATATTGGACAATGAATTTATAAAAGAAAATCCATCGGG
CAATTATAGTTTATATATTTTAAAAAAATCAAATATTGAAAATTTAAAGGCATTAAATTATATCTCTAAAAATTGCAATA
TTCCGATAAATGATATAGGATACTGCGGTTTAAAAGATAAATATGCTATAACAACACAATATATTTCAATACCTACAAAA
TACGATAAAATTGAATTAAATGAGAAAAATTTAACATTAAAATATTTAAAAACAATAAATAGTCCCTTAAAAATTGGTAG
TTTAATGGGAAATTCTTTTAAAATTACAGTTAGGGCAATTGATAAAAACGATTTTTCAAATATTTCTAAAAATTTACAGA
ATTTGGAGCAAGGAGCTCCTAACTATTTTGATGACCAAAGATTTGGAAGTGTATTTCATAATCAATTTATAGCAAAATAT
TATTTAAAAGGAGAATATGAAAAAGCATTAAAAATAATACTTACAGAATATACAAGAAGTGAAAATAAACGAATAAAGGA
CTTAAAAAGAAACATAAAAAAGAACTGGAATAAATGGGACAATATAATAGAATATATTAAAAATAATAAAATAAACAGTA
AAATGTTTGTCAACATTATAAAATATTTAAATAATCCAGAACGAAATAACAACTATAAAGAAGCTTTTAAATATGTTGAT
AATCGATTAAAAAAGCTTTTTGTATTATCCTATCAAAGTTATTTATGGAATGAATGTATAAAGGAGCTCCTAAAAACTAA
ACTACCAAAGGAACAAAGAAAATATGTAGATTATAGCTGTGGAACATTCTTATATTATTCAAAAATAGATAATGAATTAT
TTAATACCTTAAAAAAAGATAAATTCCCAACCATCGCCCCCGATATAGATTATAATAATCATAAAGACGAATACTATAAC
ATAATATTAAAAATATTAAGAAAAGAACGAGCCTCTTTAAAAGATTTTAATAATTTAATGGAATTAAATAAACTGTCTTA
TGTGGAACGGGATATATTAAATATTCCAAAAAATATTAAATATGGGGATTTTGAGCCCGATGAGTTTAACAAAGGAAAAT
ATAAAATAACAATAGAATTTGAATTAAATAAAGGTAGTTATGCCACCATAATCATAAAAAGAATATTTAATATTCAATAA

Upstream 100 bases:

>100_bases
AGTTAGAATTTATCTAATTAATTAATTTTTTTTATTTATTATTAATCTTATATTGGTATTTATTATTTATTAATTATTTT
AACATTTCAGGTAATATATT

Downstream 100 bases:

>100_bases
TATATATCAAAAATATATTTATTCCATTTTTCCCATAAATCTGTAGTATTTTTATTTATTTCAAAGAATCCCATTATCAT
ATAATAATTTCCTATTTTTC

Product: tRNA pseudouridine synthase D

Products: NA

Alternate protein names: tRNA pseudouridylate synthase D 1; tRNA-uridine isomerase D 1 [H]

Number of amino acids: Translated: 399; Mature: 399

Protein sequence:

>399_residues
MKLRQTNGDFIVNEILDNEFIKENPSGNYSLYILKKSNIENLKALNYISKNCNIPINDIGYCGLKDKYAITTQYISIPTK
YDKIELNEKNLTLKYLKTINSPLKIGSLMGNSFKITVRAIDKNDFSNISKNLQNLEQGAPNYFDDQRFGSVFHNQFIAKY
YLKGEYEKALKIILTEYTRSENKRIKDLKRNIKKNWNKWDNIIEYIKNNKINSKMFVNIIKYLNNPERNNNYKEAFKYVD
NRLKKLFVLSYQSYLWNECIKELLKTKLPKEQRKYVDYSCGTFLYYSKIDNELFNTLKKDKFPTIAPDIDYNNHKDEYYN
IILKILRKERASLKDFNNLMELNKLSYVERDILNIPKNIKYGDFEPDEFNKGKYKITIEFELNKGSYATIIIKRIFNIQ

Sequences:

>Translated_399_residues
MKLRQTNGDFIVNEILDNEFIKENPSGNYSLYILKKSNIENLKALNYISKNCNIPINDIGYCGLKDKYAITTQYISIPTK
YDKIELNEKNLTLKYLKTINSPLKIGSLMGNSFKITVRAIDKNDFSNISKNLQNLEQGAPNYFDDQRFGSVFHNQFIAKY
YLKGEYEKALKIILTEYTRSENKRIKDLKRNIKKNWNKWDNIIEYIKNNKINSKMFVNIIKYLNNPERNNNYKEAFKYVD
NRLKKLFVLSYQSYLWNECIKELLKTKLPKEQRKYVDYSCGTFLYYSKIDNELFNTLKKDKFPTIAPDIDYNNHKDEYYN
IILKILRKERASLKDFNNLMELNKLSYVERDILNIPKNIKYGDFEPDEFNKGKYKITIEFELNKGSYATIIIKRIFNIQ
>Mature_399_residues
MKLRQTNGDFIVNEILDNEFIKENPSGNYSLYILKKSNIENLKALNYISKNCNIPINDIGYCGLKDKYAITTQYISIPTK
YDKIELNEKNLTLKYLKTINSPLKIGSLMGNSFKITVRAIDKNDFSNISKNLQNLEQGAPNYFDDQRFGSVFHNQFIAKY
YLKGEYEKALKIILTEYTRSENKRIKDLKRNIKKNWNKWDNIIEYIKNNKINSKMFVNIIKYLNNPERNNNYKEAFKYVD
NRLKKLFVLSYQSYLWNECIKELLKTKLPKEQRKYVDYSCGTFLYYSKIDNELFNTLKKDKFPTIAPDIDYNNHKDEYYN
IILKILRKERASLKDFNNLMELNKLSYVERDILNIPKNIKYGDFEPDEFNKGKYKITIEFELNKGSYATIIIKRIFNIQ

Specific function: Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs [H]

COG id: COG0585

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 TRUD domain [H]

Homologues:

Organism=Homo sapiens, GI50727002, Length=408, Percent_Identity=22.5490196078431, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI148762985, Length=413, Percent_Identity=23.728813559322, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI148762961, Length=413, Percent_Identity=23.728813559322, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI148762948, Length=413, Percent_Identity=23.728813559322, Blast_Score=82, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17557232, Length=405, Percent_Identity=23.2098765432099, Blast_Score=75, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6324817, Length=255, Percent_Identity=28.2352941176471, Blast_Score=81, Evalue=4e-16,
Organism=Drosophila melanogaster, GI21355799, Length=250, Percent_Identity=26, Blast_Score=73, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020103
- InterPro:   IPR001656
- InterPro:   IPR020119
- InterPro:   IPR011760 [H]

Pfam domain/function: PF01142 TruD [H]

EC number: NA

Molecular weight: Translated: 47513; Mature: 47513

Theoretical pI: Translated: 9.84; Mature: 9.84

Prosite motif: PS50984 TRUD ; PS01268 UPF0024

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLRQTNGDFIVNEILDNEFIKENPSGNYSLYILKKSNIENLKALNYISKNCNIPINDIG
CCCCCCCCCCHHHHHHCCHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHCCCCCCCCCCC
YCGLKDKYAITTQYISIPTKYDKIELNEKNLTLKYLKTINSPLKIGSLMGNSFKITVRAI
CCCCCCCEEEEEEEEECCCCCCEEEECCCCCHHHHHHHCCCCHHHHHHCCCCEEEEEEEE
DKNDFSNISKNLQNLEQGAPNYFDDQRFGSVFHNQFIAKYYLKGEYEKALKIILTEYTRS
CCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCC
ENKRIKDLKRNIKKNWNKWDNIIEYIKNNKINSKMFVNIIKYLNNPERNNNYKEAFKYVD
CCHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHH
NRLKKLFVLSYQSYLWNECIKELLKTKLPKEQRKYVDYSCGTFLYYSKIDNELFNTLKKD
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHC
KFPTIAPDIDYNNHKDEYYNIILKILRKERASLKDFNNLMELNKLSYVERDILNIPKNIK
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
YGDFEPDEFNKGKYKITIEFELNKGSYATIIIKRIFNIQ
CCCCCCCCCCCCEEEEEEEEEECCCCCHHHHHHHHHCCC
>Mature Secondary Structure
MKLRQTNGDFIVNEILDNEFIKENPSGNYSLYILKKSNIENLKALNYISKNCNIPINDIG
CCCCCCCCCCHHHHHHCCHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHCCCCCCCCCCC
YCGLKDKYAITTQYISIPTKYDKIELNEKNLTLKYLKTINSPLKIGSLMGNSFKITVRAI
CCCCCCCEEEEEEEEECCCCCCEEEECCCCCHHHHHHHCCCCHHHHHHCCCCEEEEEEEE
DKNDFSNISKNLQNLEQGAPNYFDDQRFGSVFHNQFIAKYYLKGEYEKALKIILTEYTRS
CCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCC
ENKRIKDLKRNIKKNWNKWDNIIEYIKNNKINSKMFVNIIKYLNNPERNNNYKEAFKYVD
CCHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHH
NRLKKLFVLSYQSYLWNECIKELLKTKLPKEQRKYVDYSCGTFLYYSKIDNELFNTLKKD
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHC
KFPTIAPDIDYNNHKDEYYNIILKILRKERASLKDFNNLMELNKLSYVERDILNIPKNIK
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
YGDFEPDEFNKGKYKITIEFELNKGSYATIIIKRIFNIQ
CCCCCCCCCCCCEEEEEEEEEECCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA