| Definition | Methanococcus aeolicus Nankai-3, complete genome. |
|---|---|
| Accession | NC_009635 |
| Length | 1,569,500 |
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The map label for this gene is coaBC [H]
Identifier: 150401510
GI number: 150401510
Start: 1136604
End: 1137830
Strand: Reverse
Name: coaBC [H]
Synonym: Maeo_1087
Alternate gene names: 150401510
Gene position: 1137830-1136604 (Counterclockwise)
Preceding gene: 150401514
Following gene: 150401509
Centisome position: 72.5
GC content: 29.91
Gene sequence:
>1227_bases ATGCACCCTACAAAAAAATTAAAATATGCTAAATCAAAACTATTGGATGGTAAAACTATTGTTGTTGCAGTGTCATCATC AATTGCAGCAATTGAGACTCCAAAGTTAATGAGGGAGCTCCTAAGACATGGGGCTGATGTGAGATGTATTGCCACAGAGG AATCAAGAAAAATAATTGGAGAGGCATCATTGGAGTTTGGTTGCGGAGCTCCGATAGATTACGACATCACCGGAAAAATT GAGCATGTGGAATTATATGAAGAATGTGATGCAATGCTAATATTCCCAGCTACGGCAAATATAGTAAGTAAAATATCATT AGGTATTGCAGATAATATAATAAATACTACGGCTACAATGTTTTTTGAGAAAAAGCCAATATTTATAGTTCCAGCAATGC ACCAAAATATGATAGATACAATAGACAACCATTTAATTAATTTAAGTGGTAAAAAAGATGTACATATAATATCTCCGAAA ATGGAGGAAGAAAAGGCAAAAGTTCCATCAATTGAAACTGTTGTAGGTGAAGTTATCGATAAATTAAATAAAAAAGAAAA TAAAGATAACAATAACAACAATAAAAAAGTATTAATATTATCGGGTGGAACGGCGGAATTTATTGATAAAGTTAGAATAA TAAGCAATTTATCTTCTGGAAAAACTGGTTATTTGCTTTCTCAGTGCTTTATTAAAGATGGTTTTGATGTATCTGTTATA TATGCAATGGGCAAAAAACCACCATATTATGTAAATTCATACAATACGCTCAGTGCTACGGAAATGTTAAATAAAGCATT GGATATTGGAAAAGATGCAGATATAATAATCTCCTGTGCAGCAATATCGGATTATACTCCATTGGAAGAGCAAAAGGGAA AAATAAGTTCGGATAAAGAGGAATTAACAATAAAATTAAAGAAAAATCCAAAAGTAATAAAAGAACTTAAAAAGGCATTT CCAAATAAAATAATTGTTGGATTTAAGGCAGAATATGGAATACCAGAACAGGAATTAATTGAAAAAAGTATAAAAAAACT TAAAGATGCCAATTTAGATTATATTGTAGCCAATGATTTATCCAAACATTATTTTGGCGATGATTACAACGAGGTAATTT TAATAGATAAAAATAATAATATTAAAAAATACAAGGGCAAAAAATCCGATATAATGGAAAATATTAAAAATGAAATTATA GCCAATCTTCGAACTTTTTCGCACTAA
Upstream 100 bases:
>100_bases TACAATATATATACAATATATGGATATGTTTTATAGTTTAATAATATTATATAGTTTATTATGTTATTTAATATATACCC ACAAATATAAAAGTGATAAA
Downstream 100 bases:
>100_bases TGGAGATAAGACTGTATTATGTATAGTATCCCATATTACACTTAATATTTAGAAAATACATAGGACAGTTTTTGAAGATT GACAGATAGCCAATCTTCGG
Product: phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase
Products: NA
Alternate protein names: DNA/pantothenate metabolism flavoprotein; Phosphopantothenoylcysteine decarboxylase; PPCDC; CoaC; Phosphopantothenate--cysteine ligase; CoaB; PPC synthetase; PPCS; Phosphopantothenoylcysteine synthase [H]
Number of amino acids: Translated: 408; Mature: 408
Protein sequence:
>408_residues MHPTKKLKYAKSKLLDGKTIVVAVSSSIAAIETPKLMRELLRHGADVRCIATEESRKIIGEASLEFGCGAPIDYDITGKI EHVELYEECDAMLIFPATANIVSKISLGIADNIINTTATMFFEKKPIFIVPAMHQNMIDTIDNHLINLSGKKDVHIISPK MEEEKAKVPSIETVVGEVIDKLNKKENKDNNNNNKKVLILSGGTAEFIDKVRIISNLSSGKTGYLLSQCFIKDGFDVSVI YAMGKKPPYYVNSYNTLSATEMLNKALDIGKDADIIISCAAISDYTPLEEQKGKISSDKEELTIKLKKNPKVIKELKKAF PNKIIVGFKAEYGIPEQELIEKSIKKLKDANLDYIVANDLSKHYFGDDYNEVILIDKNNNIKKYKGKKSDIMENIKNEII ANLRTFSH
Sequences:
>Translated_408_residues MHPTKKLKYAKSKLLDGKTIVVAVSSSIAAIETPKLMRELLRHGADVRCIATEESRKIIGEASLEFGCGAPIDYDITGKI EHVELYEECDAMLIFPATANIVSKISLGIADNIINTTATMFFEKKPIFIVPAMHQNMIDTIDNHLINLSGKKDVHIISPK MEEEKAKVPSIETVVGEVIDKLNKKENKDNNNNNKKVLILSGGTAEFIDKVRIISNLSSGKTGYLLSQCFIKDGFDVSVI YAMGKKPPYYVNSYNTLSATEMLNKALDIGKDADIIISCAAISDYTPLEEQKGKISSDKEELTIKLKKNPKVIKELKKAF PNKIIVGFKAEYGIPEQELIEKSIKKLKDANLDYIVANDLSKHYFGDDYNEVILIDKNNNIKKYKGKKSDIMENIKNEII ANLRTFSH >Mature_408_residues MHPTKKLKYAKSKLLDGKTIVVAVSSSIAAIETPKLMRELLRHGADVRCIATEESRKIIGEASLEFGCGAPIDYDITGKI EHVELYEECDAMLIFPATANIVSKISLGIADNIINTTATMFFEKKPIFIVPAMHQNMIDTIDNHLINLSGKKDVHIISPK MEEEKAKVPSIETVVGEVIDKLNKKENKDNNNNNKKVLILSGGTAEFIDKVRIISNLSSGKTGYLLSQCFIKDGFDVSVI YAMGKKPPYYVNSYNTLSATEMLNKALDIGKDADIIISCAAISDYTPLEEQKGKISSDKEELTIKLKKNPKVIKELKKAF PNKIIVGFKAEYGIPEQELIEKSIKKLKDANLDYIVANDLSKHYFGDDYNEVILIDKNNNIKKYKGKKSDIMENIKNEII ANLRTFSH
Specific function: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine [H]
COG id: COG0452
COG function: function code H; Phosphopantothenoylcysteine synthetase/decarboxylase
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: In the C-terminal section; belongs to the PPC synthetase family [H]
Homologues:
Organism=Escherichia coli, GI87082301, Length=394, Percent_Identity=29.6954314720812, Blast_Score=149, Evalue=3e-37,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR005252 - InterPro: IPR007085 - InterPro: IPR003382 [H]
Pfam domain/function: PF04127 DFP; PF02441 Flavoprotein [H]
EC number: =4.1.1.36; =6.3.2.5 [H]
Molecular weight: Translated: 45563; Mature: 45563
Theoretical pI: Translated: 8.40; Mature: 8.40
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.2 %Cys (Translated Protein) 2.5 %Met (Translated Protein) 3.7 %Cys+Met (Translated Protein) 1.2 %Cys (Mature Protein) 2.5 %Met (Mature Protein) 3.7 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MHPTKKLKYAKSKLLDGKTIVVAVSSSIAAIETPKLMRELLRHGADVRCIATEESRKIIG CCCHHHHHHHHHHHCCCCEEEEEECCCCCEECCHHHHHHHHHCCCCEEEEECCCHHHHHH EASLEFGCGAPIDYDITGKIEHVELYEECDAMLIFPATANIVSKISLGIADNIINTTATM CCCCCCCCCCCCCCCCCCCEEEEEHHHHCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHE FFEKKPIFIVPAMHQNMIDTIDNHLINLSGKKDVHIISPKMEEEKAKVPSIETVVGEVID EEECCCEEEECCHHHHHHHHHHHHEEECCCCCCEEEECCCCCHHHHCCCHHHHHHHHHHH KLNKKENKDNNNNNKKVLILSGGTAEFIDKVRIISNLSSGKTGYLLSQCFIKDGFDVSVI HHHHHCCCCCCCCCCEEEEEECCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCEEEE YAMGKKPPYYVNSYNTLSATEMLNKALDIGKDADIIISCAAISDYTPLEEQKGKISSDKE EEECCCCCEEECCCCCHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCHHHCCCCCCCCE ELTIKLKKNPKVIKELKKAFPNKIIVGFKAEYGIPEQELIEKSIKKLKDANLDYIVANDL EEEEEECCCCHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEECCC SKHYFGDDYNEVILIDKNNNIKKYKGKKSDIMENIKNEIIANLRTFSH HHHCCCCCCCEEEEEECCCCCHHCCCCHHHHHHHHHHHHHHHHHHCCC >Mature Secondary Structure MHPTKKLKYAKSKLLDGKTIVVAVSSSIAAIETPKLMRELLRHGADVRCIATEESRKIIG CCCHHHHHHHHHHHCCCCEEEEEECCCCCEECCHHHHHHHHHCCCCEEEEECCCHHHHHH EASLEFGCGAPIDYDITGKIEHVELYEECDAMLIFPATANIVSKISLGIADNIINTTATM CCCCCCCCCCCCCCCCCCCEEEEEHHHHCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHE FFEKKPIFIVPAMHQNMIDTIDNHLINLSGKKDVHIISPKMEEEKAKVPSIETVVGEVID EEECCCEEEECCHHHHHHHHHHHHEEECCCCCCEEEECCCCCHHHHCCCHHHHHHHHHHH KLNKKENKDNNNNNKKVLILSGGTAEFIDKVRIISNLSSGKTGYLLSQCFIKDGFDVSVI HHHHHCCCCCCCCCCEEEEEECCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCEEEE YAMGKKPPYYVNSYNTLSATEMLNKALDIGKDADIIISCAAISDYTPLEEQKGKISSDKE EEECCCCCEEECCCCCHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCHHHCCCCCCCCE ELTIKLKKNPKVIKELKKAFPNKIIVGFKAEYGIPEQELIEKSIKKLKDANLDYIVANDL EEEEEECCCCHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEECCC SKHYFGDDYNEVILIDKNNNIKKYKGKKSDIMENIKNEIIANLRTFSH HHHCCCCCCCEEEEEECCCCCHHCCCCHHHHHHHHHHHHHHHHHHCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 8688087 [H]