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The map label for this gene is ycaK [H]

Identifier: 150398685

GI number: 150398685

Start: 3706213

End: 3706803

Strand: Direct

Name: ycaK [H]

Synonym: Smed_3499

Alternate gene names: 150398685

Gene position: 3706213-3706803 (Clockwise)

Preceding gene: 150398684

Following gene: 150398687

Centisome position: 98.0

GC content: 61.59

Gene sequence:

>591_bases
ATGCGGATACTCCTGGTGCTTGCCCACCCGCTCGAGAATAGCTTTGCGGCAAGCGTCGCCAGAACAGCCAAGGAGAGCCT
GGAGGCGAAAGGCCACACGGTTGATCTGCTCGATCTGTATCGAGACGGCTTCGATCCGAGGCTGACCGTTGCTGAACGCG
GCAGCTATTTCGACGAGCGCTACGACTCCTCGGAGGTCTCCGTCTGGGTCGACCGACTCAAGGCCGCGGACGGGCTCATG
CTCGTCTTTCCACAATGGTGGTTCAATTTCCCGGCGATCCTCAAAGGTTTCTTCGATCGTGTCTTCGCTCCCGGGGTCGC
TTTCGACCATGATCGCGCAGGCGGCCGTATCATGCCGCGGCTCGGCAACATCAAGCTATTCTGGGCGCTGACCAGTACCG
GGTCCCCCTGGTGGGTCGTGCATCTCTACATGGGAAATCCGGTGCGGCGCCTGCTGAAGCGCGGCATCGCCGCCTTCTGC
GGCAAGGGGCTCGACTTCCGCATGATCGCTCTGCACGACATGGATCGGGTGACTGAAGCGAAGCGGAAACGCCATCTCGA
GCGGGTGAGAGCGCTGGTGAGCCGGATCTGA

Upstream 100 bases:

>100_bases
GCGTTGCCGCCGTAGCGGGCGAGGACGGTACTCCTTCCCAGGCGCCGAAAAAACGACCGGCACGAGCGGGCGAGCCGACG
AAGCAGGGCAGCCTCTTCTG

Downstream 100 bases:

>100_bases
CCGGCCACCCTATTCGAATACCGCGAGGAAATTCCTGAGCAGCGCGTTCATGGCGTCCCGCTCATCCGGCTCGAGGCTCG
CGACGAGGCGCTGTTGGTTG

Product: NAD(P)H dehydrogenase (quinone)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 196; Mature: 196

Protein sequence:

>196_residues
MRILLVLAHPLENSFAASVARTAKESLEAKGHTVDLLDLYRDGFDPRLTVAERGSYFDERYDSSEVSVWVDRLKAADGLM
LVFPQWWFNFPAILKGFFDRVFAPGVAFDHDRAGGRIMPRLGNIKLFWALTSTGSPWWVVHLYMGNPVRRLLKRGIAAFC
GKGLDFRMIALHDMDRVTEAKRKRHLERVRALVSRI

Sequences:

>Translated_196_residues
MRILLVLAHPLENSFAASVARTAKESLEAKGHTVDLLDLYRDGFDPRLTVAERGSYFDERYDSSEVSVWVDRLKAADGLM
LVFPQWWFNFPAILKGFFDRVFAPGVAFDHDRAGGRIMPRLGNIKLFWALTSTGSPWWVVHLYMGNPVRRLLKRGIAAFC
GKGLDFRMIALHDMDRVTEAKRKRHLERVRALVSRI
>Mature_196_residues
MRILLVLAHPLENSFAASVARTAKESLEAKGHTVDLLDLYRDGFDPRLTVAERGSYFDERYDSSEVSVWVDRLKAADGLM
LVFPQWWFNFPAILKGFFDRVFAPGVAFDHDRAGGRIMPRLGNIKLFWALTSTGSPWWVVHLYMGNPVRRLLKRGIAAFC
GKGLDFRMIALHDMDRVTEAKRKRHLERVRALVSRI

Specific function: Unknown

COG id: COG2249

COG function: function code R; Putative NADPH-quinone reductase (modulator of drug activity B)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD(P)H dehydrogenase (quinone) family [H]

Homologues:

Organism=Homo sapiens, GI156564357, Length=124, Percent_Identity=32.258064516129, Blast_Score=69, Evalue=2e-12,
Organism=Escherichia coli, GI1787129, Length=109, Percent_Identity=40.3669724770642, Blast_Score=79, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003680 [H]

Pfam domain/function: PF02525 Flavodoxin_2 [H]

EC number: 1.6.99.- [C]

Molecular weight: Translated: 22461; Mature: 22461

Theoretical pI: Translated: 10.49; Mature: 10.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILLVLAHPLENSFAASVARTAKESLEAKGHTVDLLDLYRDGFDPRLTVAERGSYFDER
CEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCEEHHHHHHHCCCCCEEEEECCCCHHHHH
YDSSEVSVWVDRLKAADGLMLVFPQWWFNFPAILKGFFDRVFAPGVAFDHDRAGGRIMPR
CCCCHHHHHHHHHHHCCCEEEECCHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCEECCC
LGNIKLFWALTSTGSPWWVVHLYMGNPVRRLLKRGIAAFCGKGLDFRMIALHDMDRVTEA
CCCEEEEEEEECCCCCEEEEEEECCCHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHH
KRKRHLERVRALVSRI
HHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRILLVLAHPLENSFAASVARTAKESLEAKGHTVDLLDLYRDGFDPRLTVAERGSYFDER
CEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCEEHHHHHHHCCCCCEEEEECCCCHHHHH
YDSSEVSVWVDRLKAADGLMLVFPQWWFNFPAILKGFFDRVFAPGVAFDHDRAGGRIMPR
CCCCHHHHHHHHHHHCCCEEEECCHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCEECCC
LGNIKLFWALTSTGSPWWVVHLYMGNPVRRLLKRGIAAFCGKGLDFRMIALHDMDRVTEA
CCCEEEEEEEECCCCCEEEEEEECCCHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHH
KRKRHLERVRALVSRI
HHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503; 3053170; 7567469 [H]