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The map label for this gene is efp [H]

Identifier: 150398664

GI number: 150398664

Start: 3685448

End: 3686017

Strand: Direct

Name: efp [H]

Synonym: Smed_3478

Alternate gene names: 150398664

Gene position: 3685448-3686017 (Clockwise)

Preceding gene: 150398661

Following gene: 150398665

Centisome position: 97.45

GC content: 62.98

Gene sequence:

>570_bases
ATGGTCAAGGTCATCGCTTCTTCGGTCCGCAAGGGCAACGTTCTCGACGTCGACGGCAAGCTCTATGTCGTCCTCACCGC
GCAGAACTTCCATCCGGGCAAGGGCACGCCGGTCACGCAGGTCGACATGCGCCGCATTTCCGACGGCGTGAAGGTCTCCG
AGCGCTACCGCACGACCGAACAGGTCGAGCGCGCCTTCGTCGAAGACCGCGAGCACACCTTTCTTTATGAAGACGGCGAA
GGCTTCCACTTCATGAACCCGGAAACCTACGACCAGCTCGTCATGAGCACCGAAGATATCGGCGATCTGAAGGCCTATCT
GCAGGAGGGCATGGCCGTGATGCTGTCGATCCACGAGGGTCTCGCCATCGCCATCGACCTGCCGCGCCACGTCACCCTCG
AGATCGTCGAGACCGAGCCGGTCGTCAAGGGGCAGACCGCCTCCTCGTCTTACAAGCCTGCCGTGCTTTCGAACGGCGTT
CGCACGCTCGTGCCGCCGCACATCCAGGCCGGCACCCGCGTCGTCATCGCGACGGAAGACGGCTCCTACGTCGAGCGTGC
CAAGGACTGA

Upstream 100 bases:

>100_bases
AAATTAGGGTAGTGGCGGCGCGAAAACTGAACTCTCGCGTCCCTTCCGGGCCGATCTCGGCCCGCTCGTGTCGCTGATAC
CTCTCTTACAAGGAAGACTA

Downstream 100 bases:

>100_bases
TCCGGTCCTGGTCGAGGTCGAAACGGGGACGGTGGCCGAGAGCTGCCGTCCCCGTTTCCTTTTCCCGTGTCTGGTTGCAA
ATTCGGCGCGCATTTTGTGT

Product: elongation factor P

Products: NA

Alternate protein names: EF-P [H]

Number of amino acids: Translated: 189; Mature: 189

Protein sequence:

>189_residues
MVKVIASSVRKGNVLDVDGKLYVVLTAQNFHPGKGTPVTQVDMRRISDGVKVSERYRTTEQVERAFVEDREHTFLYEDGE
GFHFMNPETYDQLVMSTEDIGDLKAYLQEGMAVMLSIHEGLAIAIDLPRHVTLEIVETEPVVKGQTASSSYKPAVLSNGV
RTLVPPHIQAGTRVVIATEDGSYVERAKD

Sequences:

>Translated_189_residues
MVKVIASSVRKGNVLDVDGKLYVVLTAQNFHPGKGTPVTQVDMRRISDGVKVSERYRTTEQVERAFVEDREHTFLYEDGE
GFHFMNPETYDQLVMSTEDIGDLKAYLQEGMAVMLSIHEGLAIAIDLPRHVTLEIVETEPVVKGQTASSSYKPAVLSNGV
RTLVPPHIQAGTRVVIATEDGSYVERAKD
>Mature_189_residues
MVKVIASSVRKGNVLDVDGKLYVVLTAQNFHPGKGTPVTQVDMRRISDGVKVSERYRTTEQVERAFVEDREHTFLYEDGE
GFHFMNPETYDQLVMSTEDIGDLKAYLQEGMAVMLSIHEGLAIAIDLPRHVTLEIVETEPVVKGQTASSSYKPAVLSNGV
RTLVPPHIQAGTRVVIATEDGSYVERAKD

Specific function: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing t

COG id: COG0231

COG function: function code J; Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the elongation factor P family [H]

Homologues:

Organism=Escherichia coli, GI1790590, Length=188, Percent_Identity=36.7021276595745, Blast_Score=131, Evalue=3e-32,
Organism=Escherichia coli, GI87082061, Length=188, Percent_Identity=33.5106382978723, Blast_Score=93, Evalue=1e-20,

Paralogues:

None

Copy number: 1600 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015365
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR020599
- InterPro:   IPR013185
- InterPro:   IPR001059
- InterPro:   IPR013852
- InterPro:   IPR011768
- InterPro:   IPR014722
- InterPro:   IPR008991 [H]

Pfam domain/function: PF01132 EFP; PF08207 EFP_N; PF09285 Elong-fact-P_C [H]

EC number: NA

Molecular weight: Translated: 20948; Mature: 20948

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: PS01275 EFP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKVIASSVRKGNVLDVDGKLYVVLTAQNFHPGKGTPVTQVDMRRISDGVKVSERYRTTE
CCEEEECCCCCCCEEEECCEEEEEEEECCCCCCCCCCCHHHHHHHHHCCCCHHHHHCCHH
QVERAFVEDREHTFLYEDGEGFHFMNPETYDQLVMSTEDIGDLKAYLQEGMAVMLSIHEG
HHHHHHHCCCCCEEEEECCCCEEECCCCHHHHHHHCCCCHHHHHHHHHCCCEEEEEECCC
LAIAIDLPRHVTLEIVETEPVVKGQTASSSYKPAVLSNGVRTLVPPHIQAGTRVVIATED
EEEEEECCCCEEEEEEECCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCEEEEEECC
GSYVERAKD
CCHHHCCCC
>Mature Secondary Structure
MVKVIASSVRKGNVLDVDGKLYVVLTAQNFHPGKGTPVTQVDMRRISDGVKVSERYRTTE
CCEEEECCCCCCCEEEECCEEEEEEEECCCCCCCCCCCHHHHHHHHHCCCCHHHHHCCHH
QVERAFVEDREHTFLYEDGEGFHFMNPETYDQLVMSTEDIGDLKAYLQEGMAVMLSIHEG
HHHHHHHCCCCCEEEEECCCCEEECCCCHHHHHHHCCCCHHHHHHHHHCCCEEEEEECCC
LAIAIDLPRHVTLEIVETEPVVKGQTASSSYKPAVLSNGVRTLVPPHIQAGTRVVIATED
EEEEEECCCCEEEEEEECCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCEEEEEECC
GSYVERAKD
CCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]