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The map label for this gene is fur [H]

Identifier: 150398637

GI number: 150398637

Start: 3660338

End: 3660760

Strand: Direct

Name: fur [H]

Synonym: Smed_3451

Alternate gene names: 150398637

Gene position: 3660338-3660760 (Clockwise)

Preceding gene: 150398633

Following gene: 150398640

Centisome position: 96.79

GC content: 59.34

Gene sequence:

>423_bases
ATGACGAAAGCAACGCACATGTCCTCACAGGAGAGACTGCGCAATTCGGGTTTGCGCCCGACGCGCCAGCGCGTCGCGCT
TGCCGACCTGATTTTCGCCAAGGGCGACCGTCACCTGACGGTGGAGGAACTCCATGAGGAGGCCGTCACGGCCGGCGTTC
CCGTTTCGCTCGCGACCGTCTACAACACGCTCCATCAGTTTACCGAGGCCGGTATGATCCGCGTTCTGGCCGTCGAGAGC
GCAAGGACCTATTTCGACACGAATGTTTCGGATCACCACCATTTCTTCATCGAGGGCGAGAACGAGGTCCTCGACATCCC
TGTGAGCAATATTCAGATCGACAATCTCCCGGAACCGCCGGAAGGGATGGAAATCTCCCATGTCGACGTGGTGATCCGGC
TGCGCCATAAGGTCGAGCGCTGA

Upstream 100 bases:

>100_bases
CCTTCGCATGTGCGGAATCTATTGAAAGCCGCGGCGCCAGAAGTTATATCGCAAACTGATAAATCACGGACCCCGCAGTT
ATATATCGGAACGGCTGTCG

Downstream 100 bases:

>100_bases
GCCTTCGATCCTCTTTCTCCGTCAAACCAATCTCATCACATCACGTCGTCCGGATCGCGGCCGGGACCGGCTTTCCCGGT
CGGCAGCATCCACCCGTATC

Product: ferric uptake regulator family protein

Products: NA

Alternate protein names: Ferric uptake regulator [H]

Number of amino acids: Translated: 140; Mature: 139

Protein sequence:

>140_residues
MTKATHMSSQERLRNSGLRPTRQRVALADLIFAKGDRHLTVEELHEEAVTAGVPVSLATVYNTLHQFTEAGMIRVLAVES
ARTYFDTNVSDHHHFFIEGENEVLDIPVSNIQIDNLPEPPEGMEISHVDVVIRLRHKVER

Sequences:

>Translated_140_residues
MTKATHMSSQERLRNSGLRPTRQRVALADLIFAKGDRHLTVEELHEEAVTAGVPVSLATVYNTLHQFTEAGMIRVLAVES
ARTYFDTNVSDHHHFFIEGENEVLDIPVSNIQIDNLPEPPEGMEISHVDVVIRLRHKVER
>Mature_139_residues
TKATHMSSQERLRNSGLRPTRQRVALADLIFAKGDRHLTVEELHEEAVTAGVPVSLATVYNTLHQFTEAGMIRVLAVESA
RTYFDTNVSDHHHFFIEGENEVLDIPVSNIQIDNLPEPPEGMEISHVDVVIRLRHKVER

Specific function: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

None

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 15846; Mature: 15715

Theoretical pI: Translated: 6.02; Mature: 6.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKATHMSSQERLRNSGLRPTRQRVALADLIFAKGDRHLTVEELHEEAVTAGVPVSLATV
CCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHCCCCHHHHHH
YNTLHQFTEAGMIRVLAVESARTYFDTNVSDHHHFFIEGENEVLDIPVSNIQIDNLPEPP
HHHHHHHHHCCEEEEEEECCCHHEECCCCCCCEEEEEECCCCEEECCCCCEEECCCCCCC
EGMEISHVDVVIRLRHKVER
CCCEEHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TKATHMSSQERLRNSGLRPTRQRVALADLIFAKGDRHLTVEELHEEAVTAGVPVSLATV
CCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHCCCCHHHHHH
YNTLHQFTEAGMIRVLAVESARTYFDTNVSDHHHFFIEGENEVLDIPVSNIQIDNLPEPP
HHHHHHHHHCCEEEEEEECCCHHEECCCCCCCEEEEEECCCCEEECCCCCEEECCCCCCC
EGMEISHVDVVIRLRHKVER
CCCEEHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12910271 [H]