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The map label for this gene is nahR [H]

Identifier: 150398608

GI number: 150398608

Start: 3627958

End: 3628872

Strand: Direct

Name: nahR [H]

Synonym: Smed_3422

Alternate gene names: 150398608

Gene position: 3627958-3628872 (Clockwise)

Preceding gene: 150398604

Following gene: 150398610

Centisome position: 95.93

GC content: 67.43

Gene sequence:

>915_bases
ATGCCGAAGCCCGATCTCAACCTCCTCGTCACCCTGGACGTGCTGCTCGCCGAAGGCAGCGTCGCGCGCGCCGCGAAGCG
GCTGCGCTTGAGCCCCTCGGCCATGAGCCGGGCGCTCCAGCGGTTGCGTGAGACGACGGGCGACCCGCTTCTCGTTCGAG
CCGGGCGCGGCCTCGTTGCCACGCCGCGGGCGCTCGAACTGCGCGAGAGGGTCGGCCGGCTGGTGGAGGAAGCGGAAGCC
GTCCTGCGTCCGCAAGGAAAACTCGAGATCGAGCGGCTGGTACGGACCTTTACCCTGCGCACCAGCGATGGCTTTGTCGA
GAATTTCGGGCCCACCCTCCTTTCCCGTCTGGGCGCGGAAGCGCCCGGCGTGCGCCTGTGTTTCGTGCAGAAGCCGAACA
AGGACAGCGGTCCGCTTCGGGACGGGAGCGTCGATCTCGAGACGGGCGTCCTAGCCGAGACGACGGGGCCGGAATTACGG
ACACAAGCTCTGTTTCGCGACCGGTTCGTTGGCGTCGTTCGCAAAGGCCACGGCCTGAGCAGGGGCGAAGTGACTCCGGA
GCTTTACGCGGCCGGCAGGCATATCCTGGCCTCGCGGCGGGGCCTCGACAAGGCCGTAACAGGTATCGACGTAGCGCTGG
GGGCGATCGGGTTGGAGCGCGAGATCGTCACCACGGTGGGCGGCTTTTCGAGCGCATTGGCGCTGGCTCGCGCTTCCGAT
CTGGTCGCCAGCGTTCCGGAGCGCCACACGAGCGTTTTACGGGCCGGAATGCACAGCTTTCCGCTGCCGTTTCAGGTGCC
GCAGATCACGGTATCTCTGCTCTGGCATCCGCGGCTCCATGCCGACCCTGCGCATCGCTGGCTGCGCGGCTGCATCCGGG
AGGTATGCGGCTCAGTTGCGGTTTGCCGGCTGTAG

Upstream 100 bases:

>100_bases
GAGGCTAGCCGTTCACCTGGTATGGCGGAACCCGCACGATTTGCACTGCATTCGTGCGTTTCACGCTATATCATGACCGA
AACGGTGCTACTATCCATTC

Downstream 100 bases:

>100_bases
AAGTTTGATAGGTCGCCAGTCGGCGCAACGCGCTTCAGTCTTCGCCCTCACGCATGACCAGCCTGTTTTCGACGCTCGAA
ACGCCGATGACGGATGCGGC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 304; Mature: 303

Protein sequence:

>304_residues
MPKPDLNLLVTLDVLLAEGSVARAAKRLRLSPSAMSRALQRLRETTGDPLLVRAGRGLVATPRALELRERVGRLVEEAEA
VLRPQGKLEIERLVRTFTLRTSDGFVENFGPTLLSRLGAEAPGVRLCFVQKPNKDSGPLRDGSVDLETGVLAETTGPELR
TQALFRDRFVGVVRKGHGLSRGEVTPELYAAGRHILASRRGLDKAVTGIDVALGAIGLEREIVTTVGGFSSALALARASD
LVASVPERHTSVLRAGMHSFPLPFQVPQITVSLLWHPRLHADPAHRWLRGCIREVCGSVAVCRL

Sequences:

>Translated_304_residues
MPKPDLNLLVTLDVLLAEGSVARAAKRLRLSPSAMSRALQRLRETTGDPLLVRAGRGLVATPRALELRERVGRLVEEAEA
VLRPQGKLEIERLVRTFTLRTSDGFVENFGPTLLSRLGAEAPGVRLCFVQKPNKDSGPLRDGSVDLETGVLAETTGPELR
TQALFRDRFVGVVRKGHGLSRGEVTPELYAAGRHILASRRGLDKAVTGIDVALGAIGLEREIVTTVGGFSSALALARASD
LVASVPERHTSVLRAGMHSFPLPFQVPQITVSLLWHPRLHADPAHRWLRGCIREVCGSVAVCRL
>Mature_303_residues
PKPDLNLLVTLDVLLAEGSVARAAKRLRLSPSAMSRALQRLRETTGDPLLVRAGRGLVATPRALELRERVGRLVEEAEAV
LRPQGKLEIERLVRTFTLRTSDGFVENFGPTLLSRLGAEAPGVRLCFVQKPNKDSGPLRDGSVDLETGVLAETTGPELRT
QALFRDRFVGVVRKGHGLSRGEVTPELYAAGRHILASRRGLDKAVTGIDVALGAIGLEREIVTTVGGFSSALALARASDL
VASVPERHTSVLRAGMHSFPLPFQVPQITVSLLWHPRLHADPAHRWLRGCIREVCGSVAVCRL

Specific function: Regulates the expression of the naphthalene (nahA-F) and salicylate (nahG-M) metabolism genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081684, Length=297, Percent_Identity=25.2525252525253, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI87081766, Length=299, Percent_Identity=24.7491638795987, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1786820, Length=115, Percent_Identity=32.1739130434783, Blast_Score=68, Evalue=7e-13,

Paralogues:

None

Copy number: 825 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32963; Mature: 32832

Theoretical pI: Translated: 10.96; Mature: 10.96

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKPDLNLLVTLDVLLAEGSVARAAKRLRLSPSAMSRALQRLRETTGDPLLVRAGRGLVA
CCCCCCEEEEEEEHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCCEEEEECCCCCEE
TPRALELRERVGRLVEEAEAVLRPQGKLEIERLVRTFTLRTSDGFVENFGPTLLSRLGAE
CCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHCCHHHHHHHCCC
APGVRLCFVQKPNKDSGPLRDGSVDLETGVLAETTGPELRTQALFRDRFVGVVRKGHGLS
CCCEEEEEEECCCCCCCCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHCCCCCC
RGEVTPELYAAGRHILASRRGLDKAVTGIDVALGAIGLEREIVTTVGGFSSALALARASD
CCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHH
LVASVPERHTSVLRAGMHSFPLPFQVPQITVSLLWHPRLHADPAHRWLRGCIREVCGSVA
HHHHCHHHHHHHHHHHHHCCCCCCCCHHHEEEEEECCCCCCCHHHHHHHHHHHHHHCCHH
VCRL
CCCC
>Mature Secondary Structure 
PKPDLNLLVTLDVLLAEGSVARAAKRLRLSPSAMSRALQRLRETTGDPLLVRAGRGLVA
CCCCCEEEEEEEHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCCEEEEECCCCCEE
TPRALELRERVGRLVEEAEAVLRPQGKLEIERLVRTFTLRTSDGFVENFGPTLLSRLGAE
CCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHCCHHHHHHHCCC
APGVRLCFVQKPNKDSGPLRDGSVDLETGVLAETTGPELRTQALFRDRFVGVVRKGHGLS
CCCEEEEEEECCCCCCCCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHCCCCCC
RGEVTPELYAAGRHILASRRGLDKAVTGIDVALGAIGLEREIVTTVGGFSSALALARASD
CCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHH
LVASVPERHTSVLRAGMHSFPLPFQVPQITVSLLWHPRLHADPAHRWLRGCIREVCGSVA
HHHHCHHHHHHHHHHHHHCCCCCCCCHHHEEEEEECCCCCCCHHHHHHHHHHHHHHCCHH
VCRL
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2703465; 2848005 [H]