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The map label for this gene is glk [H]

Identifier: 150398558

GI number: 150398558

Start: 3570692

End: 3571711

Strand: Direct

Name: glk [H]

Synonym: Smed_3369

Alternate gene names: 150398558

Gene position: 3570692-3571711 (Clockwise)

Preceding gene: 150398557

Following gene: 150398559

Centisome position: 94.42

GC content: 64.51

Gene sequence:

>1020_bases
ATGCCCAATGCGAGTGACCAAAGCTTCCCCTTTCCGATTTTGATCGGCGACATCGGCGGCACCAATGCCCGCTTCGCATT
GCTTACCGACGCCTATGGCGAGCCGAGGCAGCTTGAGCCGATCAGGACGGGCGATTTCGCCACCATCGAAGAGGCAATGC
AGAAAAGCATCCTCGACAAGACTTCCGTCCAGCCGCGCTCGGCGATTCTTGCCGTAGCGGGGCCGATCAAGGGCGACGAG
ATACCGCTGACGAATGCCCATTGGGTGATTCGCCCGAAGGATATGCTGGCGAGCCTCGGCCTCGAAGACGTGCTGATCAT
CAATGATTTCGAGGCGCAGGCGCTCGCCATTGCCGCCCCGGCCGACCAGGACGTCGTGCAGATCGGCGGCGGCGCGGTCC
GGCCCTTCAATTCGCGCGTCGTCCTTGGTCCGGGTACCGGTCTGGGGGTCGCGGGCCTCGTCTATGCGCAGCACAGCTGG
ATACCCGTCCCCGGAGAAGGCGGGCATGTCGATTTAGGTCCGCGCACCGAGCGCGACTTTGAGATATGGCCGTTTCTGGA
GCCGATCGAGGGGCGCATGGCCGGCGAGCAGATACTGTGCGGCCGCGGCATCATGAATCTCTATCGCGCGGTCTGCGCCG
CCAATGGCGAAGCGGCGGTTCTCGCGGATCAGGCGGCGGTGACGACGAGTGCGTTGTCCGGTGCGGATGCCGCGGCGGTC
GAAACCGTGTCGCTCTTTGCGACTTATCTCGGGCGCGTTGCCGGCGATATGGCGCTTATCTTCATGGCGCGGGGCGGGGT
ATTCCTTGCCGGCGGCATTTCGCAGAAGATCCTGCCGGCGCTGATGAAGCCTGAGTTCCGCGCCGCCTTCGAGGACAAGG
CGCCACATTCGGCGCTGATGCGGACGATCCCGACCTTTGCCGTCATCCACCCGATGGCCGCGCTCTCCGGCCTCGCAGCC
TTTGCCCGCACGCCGAGGGACTTCGGTGTTGCAATGGAGGGACGCCGCTGGAGAAGGTGA

Upstream 100 bases:

>100_bases
GGGCAACGACATGCACAAGCAAGGATATAAATCGGGCGCATGAAATGCGGCCCGCTTTACCCCGGACATCCACGCCCGCG
ATCAGGACGGAAATTCTGCC

Downstream 100 bases:

>100_bases
CGCCGCGGCCGGCTCCGAGACTCGCCAAATCCGCAGCAAACCACTATAGAGCCCCGGAAAGCGATGCCGGTGTGCGGTAC
GCGAGCGGGCTCAGGGAAGA

Product: glucokinase

Products: NA

Alternate protein names: Glucose kinase [H]

Number of amino acids: Translated: 339; Mature: 338

Protein sequence:

>339_residues
MPNASDQSFPFPILIGDIGGTNARFALLTDAYGEPRQLEPIRTGDFATIEEAMQKSILDKTSVQPRSAILAVAGPIKGDE
IPLTNAHWVIRPKDMLASLGLEDVLIINDFEAQALAIAAPADQDVVQIGGGAVRPFNSRVVLGPGTGLGVAGLVYAQHSW
IPVPGEGGHVDLGPRTERDFEIWPFLEPIEGRMAGEQILCGRGIMNLYRAVCAANGEAAVLADQAAVTTSALSGADAAAV
ETVSLFATYLGRVAGDMALIFMARGGVFLAGGISQKILPALMKPEFRAAFEDKAPHSALMRTIPTFAVIHPMAALSGLAA
FARTPRDFGVAMEGRRWRR

Sequences:

>Translated_339_residues
MPNASDQSFPFPILIGDIGGTNARFALLTDAYGEPRQLEPIRTGDFATIEEAMQKSILDKTSVQPRSAILAVAGPIKGDE
IPLTNAHWVIRPKDMLASLGLEDVLIINDFEAQALAIAAPADQDVVQIGGGAVRPFNSRVVLGPGTGLGVAGLVYAQHSW
IPVPGEGGHVDLGPRTERDFEIWPFLEPIEGRMAGEQILCGRGIMNLYRAVCAANGEAAVLADQAAVTTSALSGADAAAV
ETVSLFATYLGRVAGDMALIFMARGGVFLAGGISQKILPALMKPEFRAAFEDKAPHSALMRTIPTFAVIHPMAALSGLAA
FARTPRDFGVAMEGRRWRR
>Mature_338_residues
PNASDQSFPFPILIGDIGGTNARFALLTDAYGEPRQLEPIRTGDFATIEEAMQKSILDKTSVQPRSAILAVAGPIKGDEI
PLTNAHWVIRPKDMLASLGLEDVLIINDFEAQALAIAAPADQDVVQIGGGAVRPFNSRVVLGPGTGLGVAGLVYAQHSWI
PVPGEGGHVDLGPRTERDFEIWPFLEPIEGRMAGEQILCGRGIMNLYRAVCAANGEAAVLADQAAVTTSALSGADAAAVE
TVSLFATYLGRVAGDMALIFMARGGVFLAGGISQKILPALMKPEFRAAFEDKAPHSALMRTIPTFAVIHPMAALSGLAAF
ARTPRDFGVAMEGRRWRR

Specific function: Not Highly Important In E.Coli As Glucose Is Transported Into The Cell By The Pts System Already As Glucose 6-Phosphate. [C]

COG id: COG0837

COG function: function code G; Glucokinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial glucokinase family [H]

Homologues:

Organism=Escherichia coli, GI1788732, Length=310, Percent_Identity=36.4516129032258, Blast_Score=196, Evalue=1e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003836 [H]

Pfam domain/function: PF02685 Glucokinase [H]

EC number: =2.7.1.2 [H]

Molecular weight: Translated: 35926; Mature: 35795

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNASDQSFPFPILIGDIGGTNARFALLTDAYGEPRQLEPIRTGDFATIEEAMQKSILDK
CCCCCCCCCCCEEEEECCCCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
TSVQPRSAILAVAGPIKGDEIPLTNAHWVIRPKDMLASLGLEDVLIINDFEAQALAIAAP
CCCCCCCEEEEEECCCCCCCCCCCCCEEEECCHHHHHHCCCCEEEEEECCCCCEEEEECC
ADQDVVQIGGGAVRPFNSRVVLGPGTGLGVAGLVYAQHSWIPVPGEGGHVDLGPRTERDF
CCCCCEEECCCEECCCCCEEEEECCCCCCHHHHEEECCCEEECCCCCCEECCCCCCCCCC
EIWPFLEPIEGRMAGEQILCGRGIMNLYRAVCAANGEAAVLADQAAVTTSALSGADAAAV
EECCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHCCCCHHHH
ETVSLFATYLGRVAGDMALIFMARGGVFLAGGISQKILPALMKPEFRAAFEDKAPHSALM
HHHHHHHHHHHHHHHHEEEEEEECCCEEEECCCHHHHHHHHHCCHHHHHHCCCCCHHHHH
RTIPTFAVIHPMAALSGLAAFARTPRDFGVAMEGRRWRR
HHHHHHHHHHHHHHHHHHHHHHCCCHHHCEEECCCCCCC
>Mature Secondary Structure 
PNASDQSFPFPILIGDIGGTNARFALLTDAYGEPRQLEPIRTGDFATIEEAMQKSILDK
CCCCCCCCCCEEEEECCCCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
TSVQPRSAILAVAGPIKGDEIPLTNAHWVIRPKDMLASLGLEDVLIINDFEAQALAIAAP
CCCCCCCEEEEEECCCCCCCCCCCCCEEEECCHHHHHHCCCCEEEEEECCCCCEEEEECC
ADQDVVQIGGGAVRPFNSRVVLGPGTGLGVAGLVYAQHSWIPVPGEGGHVDLGPRTERDF
CCCCCEEECCCEECCCCCEEEEECCCCCCHHHHEEECCCEEECCCCCCEECCCCCCCCCC
EIWPFLEPIEGRMAGEQILCGRGIMNLYRAVCAANGEAAVLADQAAVTTSALSGADAAAV
EECCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHCCCCHHHH
ETVSLFATYLGRVAGDMALIFMARGGVFLAGGISQKILPALMKPEFRAAFEDKAPHSALM
HHHHHHHHHHHHHHHHEEEEEEECCCEEEECCCHHHHHHHHHCCHHHHHHCCCCCHHHHH
RTIPTFAVIHPMAALSGLAAFARTPRDFGVAMEGRRWRR
HHHHHHHHHHHHHHHHHHHHHHCCCHHHCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]