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The map label for this gene is pamO [H]

Identifier: 150398505

GI number: 150398505

Start: 3508630

End: 3509967

Strand: Direct

Name: pamO [H]

Synonym: Smed_3315

Alternate gene names: 150398505

Gene position: 3508630-3509967 (Clockwise)

Preceding gene: 150398504

Following gene: 150398507

Centisome position: 92.77

GC content: 57.77

Gene sequence:

>1338_bases
ATGACAAGAGTTGCCGTCATCGGTGCCGGTCCATCGGGCCTTGCTCAATTGCGGGCCTTTCAGTCGGCCGCCCAGAAGGG
CGCCGAGATTCCGGAAGTCGTATGCTATGAAAAGCAGGCCGACTGGGGAGGACTTTGGAATTATACCTGGCGTACCGGAC
TGGACGAATATGGCGAGCCCGTGCATGGCAGCATGTATCGCTACCTCTGGTCGAACGGCCCCAAGGAGTGCCTCGAGTTC
GCGGACTATACCTTCGAGGAGCATTTCGGCAAACCGATCGCTTCCTATCCGCCGCGCGCGGTGCTGTGGGATTATATAAA
GGGTCGCGTGGAGAAGGCGAATGTGCGCCACTGGGTGCGTTTCCACACGCCGGTTCGCATGGTGCGCTTCGACGGAGAGA
CGAAGAAGTTCACGGTGACCGCTCACAATCGTCTCGAAGACCGCATGTATGACGAAGAGTTCGACTATGTCGTCGTTGCG
AGCGGTCACTTCTCTACACCGCAGGTCCCCTATTTCGAAGGCGTGAAGACCTTCAACGGCCGGGTGCTGCATGCGCATGA
CTTCCGCGATGCGCTGGAGTTCAAGGGCAAGGACGTTCTCATCGTCGGCCGCAGCTATTCGGCCGAGGATATCGGCTCGC
AATGCTGGAAGTATGGGGCGAAATCGGTGACGACGAGCTATCGCTCCAAGCCGATGGGCTTCAACTGGCCGGAAAATTTC
GAGGAACGGCCACTGCTGACGAAGCTCGAAAACACGACGGCTCATTTCGCGGACGGCTCGACAAAGGAAGTGGACGCGCT
GATCCTGTGCACCGGCTACCAGCACCACTTTCCCTTCCTGCCCGACGAACTCAGACTCAAGACCGCAAACCGCCTTTGGG
CCGACCATCTCTACAAGGGCGTGGTCTTCGATGGGAATCCGCAGCTCTTCTACATCGGCATGCAGGATCAGTTCTATACC
TTCAACATGTTCGACGTGCAGGCCTGGTGGGCGCGCGATGTCATGATGGGCCGCATCGAGCTGCCGCCGGAAGAGGAACT
GAAGGCGAATTTCGACATGTGGCGTGCCCGCGAGGAAACGCTCGAGCATGCCGAGGAGATGATCTGGTACCAGGGCGACT
ATGTGAAGGAACTGCTCGCTGAAACCGATTATCCGAGCTTCGATATCGAAGGGGTCAACCGGACCTTCATGAAATGGGAG
CACCACAAGGCTGAAAACATCATGGGTTTTCGCAACCATGCCTATAGGTCGCTGATGACGGGCAACATGTCGCCCGAACA
CCACACTCCCTGGGTCGAAGCGCTTGACGATTCGCTCGAGGAATATCTGCGCGAGTGA

Upstream 100 bases:

>100_bases
TTTCGAAATTCGACGACGGCGAGCCGACCAGTCCCGGCACCTTTCCGGATTGACGCCCTATCCAGCGCCAAGACGACCAA
AATCAAAAGGGGAATGCTTC

Downstream 100 bases:

>100_bases
CGCTCTCCGATAATCCCGCGAAATCGCTTCGCCCTTCATCCGTATGCCGGATGAAGGGCGAAATTGTTTAGATCACGTTC
ATGTTTTTAGATCGATCCCA

Product: flavin-containing monooxygenase FMO

Products: NA

Alternate protein names: PAMO; Baeyer-Villiger monooxygenase; BVMO [H]

Number of amino acids: Translated: 445; Mature: 444

Protein sequence:

>445_residues
MTRVAVIGAGPSGLAQLRAFQSAAQKGAEIPEVVCYEKQADWGGLWNYTWRTGLDEYGEPVHGSMYRYLWSNGPKECLEF
ADYTFEEHFGKPIASYPPRAVLWDYIKGRVEKANVRHWVRFHTPVRMVRFDGETKKFTVTAHNRLEDRMYDEEFDYVVVA
SGHFSTPQVPYFEGVKTFNGRVLHAHDFRDALEFKGKDVLIVGRSYSAEDIGSQCWKYGAKSVTTSYRSKPMGFNWPENF
EERPLLTKLENTTAHFADGSTKEVDALILCTGYQHHFPFLPDELRLKTANRLWADHLYKGVVFDGNPQLFYIGMQDQFYT
FNMFDVQAWWARDVMMGRIELPPEEELKANFDMWRAREETLEHAEEMIWYQGDYVKELLAETDYPSFDIEGVNRTFMKWE
HHKAENIMGFRNHAYRSLMTGNMSPEHHTPWVEALDDSLEEYLRE

Sequences:

>Translated_445_residues
MTRVAVIGAGPSGLAQLRAFQSAAQKGAEIPEVVCYEKQADWGGLWNYTWRTGLDEYGEPVHGSMYRYLWSNGPKECLEF
ADYTFEEHFGKPIASYPPRAVLWDYIKGRVEKANVRHWVRFHTPVRMVRFDGETKKFTVTAHNRLEDRMYDEEFDYVVVA
SGHFSTPQVPYFEGVKTFNGRVLHAHDFRDALEFKGKDVLIVGRSYSAEDIGSQCWKYGAKSVTTSYRSKPMGFNWPENF
EERPLLTKLENTTAHFADGSTKEVDALILCTGYQHHFPFLPDELRLKTANRLWADHLYKGVVFDGNPQLFYIGMQDQFYT
FNMFDVQAWWARDVMMGRIELPPEEELKANFDMWRAREETLEHAEEMIWYQGDYVKELLAETDYPSFDIEGVNRTFMKWE
HHKAENIMGFRNHAYRSLMTGNMSPEHHTPWVEALDDSLEEYLRE
>Mature_444_residues
TRVAVIGAGPSGLAQLRAFQSAAQKGAEIPEVVCYEKQADWGGLWNYTWRTGLDEYGEPVHGSMYRYLWSNGPKECLEFA
DYTFEEHFGKPIASYPPRAVLWDYIKGRVEKANVRHWVRFHTPVRMVRFDGETKKFTVTAHNRLEDRMYDEEFDYVVVAS
GHFSTPQVPYFEGVKTFNGRVLHAHDFRDALEFKGKDVLIVGRSYSAEDIGSQCWKYGAKSVTTSYRSKPMGFNWPENFE
ERPLLTKLENTTAHFADGSTKEVDALILCTGYQHHFPFLPDELRLKTANRLWADHLYKGVVFDGNPQLFYIGMQDQFYTF
NMFDVQAWWARDVMMGRIELPPEEELKANFDMWRAREETLEHAEEMIWYQGDYVKELLAETDYPSFDIEGVNRTFMKWEH
HKAENIMGFRNHAYRSLMTGNMSPEHHTPWVEALDDSLEEYLRE

Specific function: Catalyzes a Baeyer-Villiger oxidation reaction, i.e., the insertion of an oxygen atom into a carbon-carbon bond adjacent to a carbonyl, which converts ketones to esters. Is most efficient with phenylacetone as substrate, leading to the formation of benzyl

COG id: COG2072

COG function: function code P; Predicted flavoprotein involved in K+ transport

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-binding monooxygenase family [H]

Homologues:

Organism=Homo sapiens, GI4503755, Length=462, Percent_Identity=24.6753246753247, Blast_Score=97, Evalue=4e-20,
Organism=Homo sapiens, GI4503759, Length=229, Percent_Identity=28.82096069869, Blast_Score=96, Evalue=9e-20,
Organism=Homo sapiens, GI4503757, Length=254, Percent_Identity=28.3464566929134, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI50541965, Length=232, Percent_Identity=31.0344827586207, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI50541961, Length=232, Percent_Identity=31.0344827586207, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI221316674, Length=231, Percent_Identity=28.1385281385281, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI221316672, Length=231, Percent_Identity=28.1385281385281, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI221316678, Length=231, Percent_Identity=28.1385281385281, Blast_Score=80, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI193202226, Length=419, Percent_Identity=25.7756563245823, Blast_Score=126, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI25145785, Length=233, Percent_Identity=33.9055793991416, Blast_Score=115, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI17506045, Length=321, Percent_Identity=29.2834890965732, Blast_Score=112, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI17541300, Length=233, Percent_Identity=29.1845493562232, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI25150462, Length=236, Percent_Identity=26.6949152542373, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17561948, Length=231, Percent_Identity=25.974025974026, Blast_Score=74, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6321970, Length=314, Percent_Identity=24.5222929936306, Blast_Score=93, Evalue=8e-20,
Organism=Drosophila melanogaster, GI19922866, Length=348, Percent_Identity=30.7471264367816, Blast_Score=155, Evalue=4e-38,
Organism=Drosophila melanogaster, GI19921694, Length=384, Percent_Identity=27.0833333333333, Blast_Score=142, Evalue=4e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020946 [H]

Pfam domain/function: PF00743 FMO-like [H]

EC number: =1.14.13.92 [H]

Molecular weight: Translated: 52020; Mature: 51889

Theoretical pI: Translated: 5.46; Mature: 5.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRVAVIGAGPSGLAQLRAFQSAAQKGAEIPEVVCYEKQADWGGLWNYTWRTGLDEYGEP
CCEEEEEECCCHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCHHHCCCHHHCCC
VHGSMYRYLWSNGPKECLEFADYTFEEHFGKPIASYPPRAVLWDYIKGRVEKANVRHWVR
CCCHHHHHHHCCCHHHHHHHHHCCHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCHHEEEE
FHTPVRMVRFDGETKKFTVTAHNRLEDRMYDEEFDYVVVASGHFSTPQVPYFEGVKTFNG
ECCCEEEEEECCCCEEEEEEECCHHHHHHCCCCCCEEEEECCCCCCCCCCHHCCCCCCCC
RVLHAHDFRDALEFKGKDVLIVGRSYSAEDIGSQCWKYGAKSVTTSYRSKPMGFNWPENF
EEEEECCHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCC
EERPLLTKLENTTAHFADGSTKEVDALILCTGYQHHFPFLPDELRLKTANRLWADHLYKG
CCCCCHHHHCCCEEECCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCC
VVFDGNPQLFYIGMQDQFYTFNMFDVQAWWARDVMMGRIELPPEEELKANFDMWRAREET
EEECCCCCEEEEECCCCEEEEEEEEEHHHHHHHHHCCEECCCCHHHHHCCHHHHHHHHHH
LEHAEEMIWYQGDYVKELLAETDYPSFDIEGVNRTFMKWEHHKAENIMGFRNHAYRSLMT
HHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
GNMSPEHHTPWVEALDDSLEEYLRE
CCCCCCCCCCHHHHHHHHHHHHHHC
>Mature Secondary Structure 
TRVAVIGAGPSGLAQLRAFQSAAQKGAEIPEVVCYEKQADWGGLWNYTWRTGLDEYGEP
CEEEEEECCCHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCHHHCCCHHHCCC
VHGSMYRYLWSNGPKECLEFADYTFEEHFGKPIASYPPRAVLWDYIKGRVEKANVRHWVR
CCCHHHHHHHCCCHHHHHHHHHCCHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCHHEEEE
FHTPVRMVRFDGETKKFTVTAHNRLEDRMYDEEFDYVVVASGHFSTPQVPYFEGVKTFNG
ECCCEEEEEECCCCEEEEEEECCHHHHHHCCCCCCEEEEECCCCCCCCCCHHCCCCCCCC
RVLHAHDFRDALEFKGKDVLIVGRSYSAEDIGSQCWKYGAKSVTTSYRSKPMGFNWPENF
EEEEECCHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCC
EERPLLTKLENTTAHFADGSTKEVDALILCTGYQHHFPFLPDELRLKTANRLWADHLYKG
CCCCCHHHHCCCEEECCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCC
VVFDGNPQLFYIGMQDQFYTFNMFDVQAWWARDVMMGRIELPPEEELKANFDMWRAREET
EEECCCCCEEEEECCCCEEEEEEEEEHHHHHHHHHCCEECCCCHHHHHCCHHHHHHHHHH
LEHAEEMIWYQGDYVKELLAETDYPSFDIEGVNRTFMKWEHHKAENIMGFRNHAYRSLMT
HHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
GNMSPEHHTPWVEALDDSLEEYLRE
CCCCCCCCCCHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA