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The map label for this gene is hyuA [H]

Identifier: 150398461

GI number: 150398461

Start: 3448396

End: 3450399

Strand: Direct

Name: hyuA [H]

Synonym: Smed_3269

Alternate gene names: 150398461

Gene position: 3448396-3450399 (Clockwise)

Preceding gene: 150398460

Following gene: 150398462

Centisome position: 91.18

GC content: 66.32

Gene sequence:

>2004_bases
TTGACCCCGCATCTTCTCCTGGGCATCGACACCGGCGGCACCTATACCGACGCCGTTCTTTTCAGCGAAACGAAGGGCGT
CGTCGCCAAGGCCAAAGCGCTCACGACCCGTCACGATCTCGCCGAGGGCGTTTCCGGTGCGGTGGAGGCAGTGCTCGCAA
AGGCGGACGTGCCGGTATCGGCGATCAGCCTCGTATCGCTGTCGACGACGCTTGCCACCAATGCGCTGGTCGAAGGCCAG
GGCGGCAGGGCCGGCCTGATCATGATCGGTTTCGCTCCGGACGACCTGAAGCGCGACGGTCTTCAGGACGCGCTCGGATC
CGATCCTGTCCTCTTCCTTCCCGGCGGCCACAATGTCCATGGCGGCGAGACGACGCTGGACATGCGTGCGCTCGACGAGG
CGCTGCCGGCGCTCGGGTCCCAGGTGTCGTCCTTCGCCGTTGCCGGCTATTTCGCGGTGCGCAACCCGGATCACGAGAAG
CGTGTTCGCGATCGCATCCGCGAGGTCTCGCACCTGCCGGTAACCTGCAGCCATGAGCTTTCCTCCAAGCTTGGCGGACC
CCGTCGCGCGCTGACGACGCTTCTGAATGCGCGGCTGGTCTCGATGATCGACCGGCTGATCGTCTCCTGCGAAGACTTCC
TCAAGGCCCGCGGCATCGACGTGCCGATGATGGTGGTACGAGGCGACGGTGCGTTGATATCGGCCGCCGAGGCGCGGCTG
CGGCCGATCGAAACGATTTTGTCGGGTCCGGCTGCGAGCCTCGTCGGCGCTCGCTATCTGACCGGCTTTGACAGCGCCGT
GGTCTCCGATATCGGCGGCACGACCACCGACGTCGCCGTCCTCGAAAAAGGCCGGCCGCGCCTCGACGCCGACGGAGCTG
TCGTCGGCGGCTTTCGCACCATGGTCGAGGCGGTCGCCATGCGCACATACGGCCTTGGCGGCGACTCGGAGGTGAAGATC
AACGATCGTGGCCTCAAGGCCAGGCTTGATCTCGGGCCCCGCCGTTTCCTGCCCCTGAGCCTTGCGGCGGCGCTGCACGG
CGACGCGGTTCTTTCGGTGCTCCAAAAGCAGTTGCGGGCGCCCCATGCCGGCCGGCATGACGGTCGCCTGGCAGTCCGCA
CCGGTTTGCCCGACCATCTCGCCAGCGGGCTTCAGCCTCAGGAACAGGCCCTTTATGATCGCATAGGAATGATACCGGTG
GCGCTTGCTGATCTTCTCGTCACCACGCCGCAGAGGGCGACCCTCGACAGGCTTGTAGCTCGCGGTCTGGTGCATCTCTG
CGGGCTCACTCCTTCGGACGCGATGCATGTTCTCGGTCGGCAGGCGCAATGGAACGGCGAGGCCGCGCGCCTCGGCCTCG
AGATTGCCGCTCGAACGAAGGACGGATCCGGCCAGCCTATCGCGGCTTCTGTCGCGGCTCTGGCGCAGATGATCGTGGAC
CGGCTGACGCGGCAGTCGTCGGAGGCCATCCTGCAGGCGTGCCTCAACGAGGACGGCGCCGGAGCGATCGATCCTGCCGT
CTCGCTTTCCGTTGACCGTGCGCTGAAACGGGAGCCCGGAATCGTGCGTTTTTCGCTCGGTATCGACCGGCCGCTTGTCG
GGCTCGGCGCCTCCGCACCGGTCTATTATCCCGCGATCGCTGAAATGCTTTCCGCCGAACCGGCAATTCCGGCTGAAGCG
GACGTGGCAAACGCCGTCGGCGCGGTTGTCGGCCAAGTGCGTACGACGGTCACCGTTTTCGTGACGACGCCGGAAGAAGG
CATTTTCATCGTCAACGGTGCCGGCGCGAGCGAGCGTTTCGTCGATCAACAGGAGGCCTTCGGCGTTGCCCGCCGCCGCG
CGAAAACGATGGCGCTCGAGAGCGCCCGCGCGAACGGTGCAGAGGACCCCGCCGCGACCCTTCGGGAAGAGATCGACGCG
CCGGAAGTCGAGGGCAGCCGCAAGCTGATCGAGGCGCGCTTCATCGCCTCGGCAAGCGGCCGGCCGCGAATCGCACATGG
CTGA

Upstream 100 bases:

>100_bases
GAGGTAGAGCGGGTCGCGCTCGCGCGATGGTTTTTCCCAAGAATATGTCCTATCACCAGATGGATTTTTCCGGATTCTCA
CCATTGGACTGAGCAGAAAA

Downstream 100 bases:

>100_bases
TCTTTTCCGTTTTGGAAACAATTCTTCGCTTCCATGCGCAATTGACAAAGATGGGCCCGGTGGGAGATTTTCCGCGCGCG
CGAGCGGGCGACGCGCTTTT

Product: hydantoinase/oxoprolinase

Products: NA

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 667; Mature: 666

Protein sequence:

>667_residues
MTPHLLLGIDTGGTYTDAVLFSETKGVVAKAKALTTRHDLAEGVSGAVEAVLAKADVPVSAISLVSLSTTLATNALVEGQ
GGRAGLIMIGFAPDDLKRDGLQDALGSDPVLFLPGGHNVHGGETTLDMRALDEALPALGSQVSSFAVAGYFAVRNPDHEK
RVRDRIREVSHLPVTCSHELSSKLGGPRRALTTLLNARLVSMIDRLIVSCEDFLKARGIDVPMMVVRGDGALISAAEARL
RPIETILSGPAASLVGARYLTGFDSAVVSDIGGTTTDVAVLEKGRPRLDADGAVVGGFRTMVEAVAMRTYGLGGDSEVKI
NDRGLKARLDLGPRRFLPLSLAAALHGDAVLSVLQKQLRAPHAGRHDGRLAVRTGLPDHLASGLQPQEQALYDRIGMIPV
ALADLLVTTPQRATLDRLVARGLVHLCGLTPSDAMHVLGRQAQWNGEAARLGLEIAARTKDGSGQPIAASVAALAQMIVD
RLTRQSSEAILQACLNEDGAGAIDPAVSLSVDRALKREPGIVRFSLGIDRPLVGLGASAPVYYPAIAEMLSAEPAIPAEA
DVANAVGAVVGQVRTTVTVFVTTPEEGIFIVNGAGASERFVDQQEAFGVARRRAKTMALESARANGAEDPAATLREEIDA
PEVEGSRKLIEARFIASASGRPRIAHG

Sequences:

>Translated_667_residues
MTPHLLLGIDTGGTYTDAVLFSETKGVVAKAKALTTRHDLAEGVSGAVEAVLAKADVPVSAISLVSLSTTLATNALVEGQ
GGRAGLIMIGFAPDDLKRDGLQDALGSDPVLFLPGGHNVHGGETTLDMRALDEALPALGSQVSSFAVAGYFAVRNPDHEK
RVRDRIREVSHLPVTCSHELSSKLGGPRRALTTLLNARLVSMIDRLIVSCEDFLKARGIDVPMMVVRGDGALISAAEARL
RPIETILSGPAASLVGARYLTGFDSAVVSDIGGTTTDVAVLEKGRPRLDADGAVVGGFRTMVEAVAMRTYGLGGDSEVKI
NDRGLKARLDLGPRRFLPLSLAAALHGDAVLSVLQKQLRAPHAGRHDGRLAVRTGLPDHLASGLQPQEQALYDRIGMIPV
ALADLLVTTPQRATLDRLVARGLVHLCGLTPSDAMHVLGRQAQWNGEAARLGLEIAARTKDGSGQPIAASVAALAQMIVD
RLTRQSSEAILQACLNEDGAGAIDPAVSLSVDRALKREPGIVRFSLGIDRPLVGLGASAPVYYPAIAEMLSAEPAIPAEA
DVANAVGAVVGQVRTTVTVFVTTPEEGIFIVNGAGASERFVDQQEAFGVARRRAKTMALESARANGAEDPAATLREEIDA
PEVEGSRKLIEARFIASASGRPRIAHG
>Mature_666_residues
TPHLLLGIDTGGTYTDAVLFSETKGVVAKAKALTTRHDLAEGVSGAVEAVLAKADVPVSAISLVSLSTTLATNALVEGQG
GRAGLIMIGFAPDDLKRDGLQDALGSDPVLFLPGGHNVHGGETTLDMRALDEALPALGSQVSSFAVAGYFAVRNPDHEKR
VRDRIREVSHLPVTCSHELSSKLGGPRRALTTLLNARLVSMIDRLIVSCEDFLKARGIDVPMMVVRGDGALISAAEARLR
PIETILSGPAASLVGARYLTGFDSAVVSDIGGTTTDVAVLEKGRPRLDADGAVVGGFRTMVEAVAMRTYGLGGDSEVKIN
DRGLKARLDLGPRRFLPLSLAAALHGDAVLSVLQKQLRAPHAGRHDGRLAVRTGLPDHLASGLQPQEQALYDRIGMIPVA
LADLLVTTPQRATLDRLVARGLVHLCGLTPSDAMHVLGRQAQWNGEAARLGLEIAARTKDGSGQPIAASVAALAQMIVDR
LTRQSSEAILQACLNEDGAGAIDPAVSLSVDRALKREPGIVRFSLGIDRPLVGLGASAPVYYPAIAEMLSAEPAIPAEAD
VANAVGAVVGQVRTTVTVFVTTPEEGIFIVNGAGASERFVDQQEAFGVARRRAKTMALESARANGAEDPAATLREEIDAP
EVEGSRKLIEARFIASASGRPRIAHG

Specific function: HyuA and hyuB convert D- and L-substituted hydantoins to corresponding N-carbamyl-amino acids [H]

COG id: COG0145

COG function: function code EQ; N-methylhydantoinase A/acetone carboxylase, beta subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the oxoprolinase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008040
- InterPro:   IPR002821 [H]

Pfam domain/function: PF05378 Hydant_A_N; PF01968 Hydantoinase_A [H]

EC number: NA

Molecular weight: Translated: 69837; Mature: 69706

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPHLLLGIDTGGTYTDAVLFSETKGVVAKAKALTTRHDLAEGVSGAVEAVLAKADVPVS
CCCCEEEEECCCCCEEHEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
AISLVSLSTTLATNALVEGQGGRAGLIMIGFAPDDLKRDGLQDALGSDPVLFLPGGHNVH
HHHHHHHHHHHHHHHEEECCCCCEEEEEEECCCCHHHHCCHHHHHCCCCEEEECCCCCCC
GGETTLDMRALDEALPALGSQVSSFAVAGYFAVRNPDHEKRVRDRIREVSHLPVTCSHEL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHCCCCEECHHH
SSKLGGPRRALTTLLNARLVSMIDRLIVSCEDFLKARGIDVPMMVVRGDGALISAAEARL
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEEHHHHHH
RPIETILSGPAASLVGARYLTGFDSAVVSDIGGTTTDVAVLEKGRPRLDADGAVVGGFRT
HHHHHHHCCCHHHHHHHHHHHCCHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCEEHHHHH
MVEAVAMRTYGLGGDSEVKINDRGLKARLDLGPRRFLPLSLAAALHGDAVLSVLQKQLRA
HHHHHHHHHCCCCCCCEEEECCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
PHAGRHDGRLAVRTGLPDHLASGLQPQEQALYDRIGMIPVALADLLVTTPQRATLDRLVA
CCCCCCCCEEEEECCCCHHHHCCCCHHHHHHHHHHCHHHHHHHHHHHCCCCHHHHHHHHH
RGLVHLCGLTPSDAMHVLGRQAQWNGEAARLGLEIAARTKDGSGQPIAASVAALAQMIVD
HHHHHHHCCCCHHHHHHHCCCCCCCCHHHHEEEEEEEECCCCCCCCHHHHHHHHHHHHHH
RLTRQSSEAILQACLNEDGAGAIDPAVSLSVDRALKREPGIVRFSLGIDRPLVGLGASAP
HHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCC
VYYPAIAEMLSAEPAIPAEADVANAVGAVVGQVRTTVTVFVTTPEEGIFIVNGAGASERF
CHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHEEEEEEEEECCCCCEEEEECCCCCHHH
VDQQEAFGVARRRAKTMALESARANGAEDPAATLREEIDAPEVEGSRKLIEARFIASASG
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCC
RPRIAHG
CCCCCCC
>Mature Secondary Structure 
TPHLLLGIDTGGTYTDAVLFSETKGVVAKAKALTTRHDLAEGVSGAVEAVLAKADVPVS
CCCEEEEECCCCCEEHEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
AISLVSLSTTLATNALVEGQGGRAGLIMIGFAPDDLKRDGLQDALGSDPVLFLPGGHNVH
HHHHHHHHHHHHHHHEEECCCCCEEEEEEECCCCHHHHCCHHHHHCCCCEEEECCCCCCC
GGETTLDMRALDEALPALGSQVSSFAVAGYFAVRNPDHEKRVRDRIREVSHLPVTCSHEL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHCCCCEECHHH
SSKLGGPRRALTTLLNARLVSMIDRLIVSCEDFLKARGIDVPMMVVRGDGALISAAEARL
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEEHHHHHH
RPIETILSGPAASLVGARYLTGFDSAVVSDIGGTTTDVAVLEKGRPRLDADGAVVGGFRT
HHHHHHHCCCHHHHHHHHHHHCCHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCEEHHHHH
MVEAVAMRTYGLGGDSEVKINDRGLKARLDLGPRRFLPLSLAAALHGDAVLSVLQKQLRA
HHHHHHHHHCCCCCCCEEEECCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
PHAGRHDGRLAVRTGLPDHLASGLQPQEQALYDRIGMIPVALADLLVTTPQRATLDRLVA
CCCCCCCCEEEEECCCCHHHHCCCCHHHHHHHHHHCHHHHHHHHHHHCCCCHHHHHHHHH
RGLVHLCGLTPSDAMHVLGRQAQWNGEAARLGLEIAARTKDGSGQPIAASVAALAQMIVD
HHHHHHHCCCCHHHHHHHCCCCCCCCHHHHEEEEEEEECCCCCCCCHHHHHHHHHHHHHH
RLTRQSSEAILQACLNEDGAGAIDPAVSLSVDRALKREPGIVRFSLGIDRPLVGLGASAP
HHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCC
VYYPAIAEMLSAEPAIPAEADVANAVGAVVGQVRTTVTVFVTTPEEGIFIVNGAGASERF
CHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHEEEEEEEEECCCCCEEEEECCCCCHHH
VDQQEAFGVARRRAKTMALESARANGAEDPAATLREEIDAPEVEGSRKLIEARFIASASG
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCC
RPRIAHG
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1732229 [H]