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The map label for this gene is hslV [H]

Identifier: 150398456

GI number: 150398456

Start: 3443126

End: 3443683

Strand: Direct

Name: hslV [H]

Synonym: Smed_3264

Alternate gene names: 150398456

Gene position: 3443126-3443683 (Clockwise)

Preceding gene: 150398448

Following gene: 150398457

Centisome position: 91.04

GC content: 62.19

Gene sequence:

>558_bases
ATGAGCGAACACAACCCTTACGGAACGATGCATGCGACCACCATCATCACGGTGCGCAAGGGCGGCAAGGTGGTGATGGC
CGGCGATGGCCAGGTGAGCCTTGGTCAGACGGTTATGAAAGGCAACGCCCGCAAGGTTCGCCGGCTGTCGAAGGGCGATG
TGATTGCAGGCTTCGCAGGCGCGACGGCGGACGCCTTCACCCTCCTCGAAAGGCTCGAGGTAAAGCTCGAGCAGTATCCC
GACCAGTTGATGCGAGCGGCCGTGGAACTCGCCAAGGACTGGCGCACCAACAAGTATCTGCGCAACCTCGAGGCCATGAT
GCTGGTCGCCGACAGATCGGTGACGCTGGCGATCACCGGAAACGGTGACGTTCTCGAGCCCGAGCACGGCACGATCGCTA
TCGGTTCGGGCGGTAACTACGCTTTTGCGGCAGCGCGGGCGCTCATGGATACCGACAGGTCGGCCGAGGAGATCGCCCGC
CGGGCGCTCGAGATCGCCGGCGACATATGCGTTTACACGAACCACAATGTCGTCTTGGAGACGCTGGATGCCGAATGA

Upstream 100 bases:

>100_bases
CACATTTGCAATCGCGCGGCCGCGACTTACATAGGCCTCAGCAACCAGGTTCATTCCGAGCCGCAATGCTCCCGGCTCCC
CGGGGACCCATAGGTATATC

Downstream 100 bases:

>100_bases
GCCGGCGGAGGTCAGCTTCGAGCCGGTGGCCGAGCGCCATCTGCCGATGCTCCTTGCCTGGCTTTCAGAGCCGCATGTCC
GGCAGTGGTGGGGCGATCCC

Product: ATP-dependent protease peptidase subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 185; Mature: 184

Protein sequence:

>185_residues
MSEHNPYGTMHATTIITVRKGGKVVMAGDGQVSLGQTVMKGNARKVRRLSKGDVIAGFAGATADAFTLLERLEVKLEQYP
DQLMRAAVELAKDWRTNKYLRNLEAMMLVADRSVTLAITGNGDVLEPEHGTIAIGSGGNYAFAAARALMDTDRSAEEIAR
RALEIAGDICVYTNHNVVLETLDAE

Sequences:

>Translated_185_residues
MSEHNPYGTMHATTIITVRKGGKVVMAGDGQVSLGQTVMKGNARKVRRLSKGDVIAGFAGATADAFTLLERLEVKLEQYP
DQLMRAAVELAKDWRTNKYLRNLEAMMLVADRSVTLAITGNGDVLEPEHGTIAIGSGGNYAFAAARALMDTDRSAEEIAR
RALEIAGDICVYTNHNVVLETLDAE
>Mature_184_residues
SEHNPYGTMHATTIITVRKGGKVVMAGDGQVSLGQTVMKGNARKVRRLSKGDVIAGFAGATADAFTLLERLEVKLEQYPD
QLMRAAVELAKDWRTNKYLRNLEAMMLVADRSVTLAITGNGDVLEPEHGTIAIGSGGNYAFAAARALMDTDRSAEEIARR
ALEIAGDICVYTNHNVVLETLDAE

Specific function: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery [H]

COG id: COG5405

COG function: function code O; ATP-dependent protease HslVU (ClpYQ), peptidase subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase T1B family. HslV subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790367, Length=171, Percent_Identity=64.327485380117, Blast_Score=218, Evalue=2e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022281
- InterPro:   IPR001353 [H]

Pfam domain/function: PF00227 Proteasome [H]

EC number: 3.4.25.-

Molecular weight: Translated: 19994; Mature: 19863

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEHNPYGTMHATTIITVRKGGKVVMAGDGQVSLGQTVMKGNARKVRRLSKGDVIAGFAG
CCCCCCCCCEEEEEEEEEECCCEEEEECCCCEECCHHHHCCCHHHHHHCCCCCEEEECCC
ATADAFTLLERLEVKLEQYPDQLMRAAVELAKDWRTNKYLRNLEAMMLVADRSVTLAITG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCEEEEEEC
NGDVLEPEHGTIAIGSGGNYAFAAARALMDTDRSAEEIARRALEIAGDICVYTNHNVVLE
CCCEECCCCCEEEEECCCCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEEEECCCEEEE
TLDAE
EECCC
>Mature Secondary Structure 
SEHNPYGTMHATTIITVRKGGKVVMAGDGQVSLGQTVMKGNARKVRRLSKGDVIAGFAG
CCCCCCCCEEEEEEEEEECCCEEEEECCCCEECCHHHHCCCHHHHHHCCCCCEEEECCC
ATADAFTLLERLEVKLEQYPDQLMRAAVELAKDWRTNKYLRNLEAMMLVADRSVTLAITG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCEEEEEEC
NGDVLEPEHGTIAIGSGGNYAFAAARALMDTDRSAEEIARRALEIAGDICVYTNHNVVLE
CCCEECCCCCEEEEECCCCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEEEECCCEEEE
TLDAE
EECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA