Click here to switch to the map view.

The map label for this gene is trpB [H]

Identifier: 150398429

GI number: 150398429

Start: 3411810

End: 3413030

Strand: Direct

Name: trpB [H]

Synonym: Smed_3237

Alternate gene names: 150398429

Gene position: 3411810-3413030 (Clockwise)

Preceding gene: 150398428

Following gene: 150398430

Centisome position: 90.21

GC content: 62.33

Gene sequence:

>1221_bases
GTGAATCAGCCGCCTAAACCGAATTCCTTCAGATCCGGACCCGATGAAGAGGGCCGTTTCGGCATATTCGGTGGCCGCTT
CGTCGCCGAGACGCTGATGCCGCTGATCCTCGACCTCCAGGACGAATGGGCGAGGGCAAAGAATGATCCGGCTTTCAAGG
CGGAGCTGGAAAATCTCGGCAGGCATTATATCGGCCGGCCGAGCCCGCTCTATTTCGCCGAGCGCCTGACGGCCGAACTC
GGCGGCGCGAAGATCTACTTCAAGCGCGAGGAGCTCAATCACACGGGCTCCCATAAGATCAATAACTGCATCGGCCAGAT
CCTGCTTGCCAAGCGCATGGGCAAGACCCGCATCATCGCCGAGACCGGCGCCGGCCAGCATGGTGTGGCATCGGCCACCG
TGGCGGCGCGTTTCGGGCTGCCTTGCGTCGTCTATATGGGGGCGACAGACGTGGAGCGGCAGGCACCGAACGTCTTCCGC
ATGAAGCTTCTCGGCGCCGAGGTGAAGCCGGTGACTGCGGGTCACGGCACCCTCAAGGACGCCATGAACGAGGCGCTGCG
GGACTGGGTGACCAATGTCGACAGCACCTATTACCTGATCGGCACGGCCGCCGGCCCGCATCCCTATCCGGAGATGGTAC
GCGACTTCCAGGCGGTCATCGGCGAGGAAGCCAAGCAGCAGATGCTCGAAGCCGAAGGCCGGCTTCCGGACCTCGTGGTT
GCAGCGGTCGGCGGTGGGTCAAATGCGATAGGCATCTTCCATCCATTCCTGGATGACGGGGGCGTCAGGATCGTCGGCGT
TGAAGCCGGTGGCAAGGGCCTGGACGGCGATGAGCATTGCGCCTCTCTCACAGCCGGCTCGCCGGGCGTGCTGCATGGCA
ACCGCACTTATCTGCTCCAGGACGGTGACGGCCAGATCAAGGAAGGCCACTCGATTTCGGCCGGGCTCGATTACCCGGGG
ATCGGACCGGAGCATGCCTGGCTGAACGATATCGGCCGCGTCGAATATGTGCCGATCATGGATCATGAGGCGCTGGAGGC
GTTTCAGATCCTGACGCGGCTCGAAGGCATCATTCCGGCGCTCGAGCCGTCCCACGCGCTTGCCGAAGTCATCAAGCGTG
CGCCGAAAATGGGCAAGGACGAGATCATCCTGATGAATCTCTCCGGTCGCGGCGACAAGGACATCTTCACCGTCGGCAAA
ATTCTCGGTATGGGGCAATAA

Upstream 100 bases:

>100_bases
GGTCGAAAGCGCACCGGGCATCAAGGATCTGACGCTCATGGATGCGTTTTTCGAGGCGATTCGCCGAGCGGAAGCTTAAG
CCACGATCAGGGAGCAAGAC

Downstream 100 bases:

>100_bases
CGAACATGACCGCACGCATGGAGCAAAGGTTCGCCGATGTGGCGGCTGAAGGGCGCCCGGTTCTCGTGACCTATTTCATG
GGCGGCGACCCGGATTTCGA

Product: tryptophan synthase subunit beta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 406; Mature: 406

Protein sequence:

>406_residues
MNQPPKPNSFRSGPDEEGRFGIFGGRFVAETLMPLILDLQDEWARAKNDPAFKAELENLGRHYIGRPSPLYFAERLTAEL
GGAKIYFKREELNHTGSHKINNCIGQILLAKRMGKTRIIAETGAGQHGVASATVAARFGLPCVVYMGATDVERQAPNVFR
MKLLGAEVKPVTAGHGTLKDAMNEALRDWVTNVDSTYYLIGTAAGPHPYPEMVRDFQAVIGEEAKQQMLEAEGRLPDLVV
AAVGGGSNAIGIFHPFLDDGGVRIVGVEAGGKGLDGDEHCASLTAGSPGVLHGNRTYLLQDGDGQIKEGHSISAGLDYPG
IGPEHAWLNDIGRVEYVPIMDHEALEAFQILTRLEGIIPALEPSHALAEVIKRAPKMGKDEIILMNLSGRGDKDIFTVGK
ILGMGQ

Sequences:

>Translated_406_residues
MNQPPKPNSFRSGPDEEGRFGIFGGRFVAETLMPLILDLQDEWARAKNDPAFKAELENLGRHYIGRPSPLYFAERLTAEL
GGAKIYFKREELNHTGSHKINNCIGQILLAKRMGKTRIIAETGAGQHGVASATVAARFGLPCVVYMGATDVERQAPNVFR
MKLLGAEVKPVTAGHGTLKDAMNEALRDWVTNVDSTYYLIGTAAGPHPYPEMVRDFQAVIGEEAKQQMLEAEGRLPDLVV
AAVGGGSNAIGIFHPFLDDGGVRIVGVEAGGKGLDGDEHCASLTAGSPGVLHGNRTYLLQDGDGQIKEGHSISAGLDYPG
IGPEHAWLNDIGRVEYVPIMDHEALEAFQILTRLEGIIPALEPSHALAEVIKRAPKMGKDEIILMNLSGRGDKDIFTVGK
ILGMGQ
>Mature_406_residues
MNQPPKPNSFRSGPDEEGRFGIFGGRFVAETLMPLILDLQDEWARAKNDPAFKAELENLGRHYIGRPSPLYFAERLTAEL
GGAKIYFKREELNHTGSHKINNCIGQILLAKRMGKTRIIAETGAGQHGVASATVAARFGLPCVVYMGATDVERQAPNVFR
MKLLGAEVKPVTAGHGTLKDAMNEALRDWVTNVDSTYYLIGTAAGPHPYPEMVRDFQAVIGEEAKQQMLEAEGRLPDLVV
AAVGGGSNAIGIFHPFLDDGGVRIVGVEAGGKGLDGDEHCASLTAGSPGVLHGNRTYLLQDGDGQIKEGHSISAGLDYPG
IGPEHAWLNDIGRVEYVPIMDHEALEAFQILTRLEGIIPALEPSHALAEVIKRAPKMGKDEIILMNLSGRGDKDIFTVGK
ILGMGQ

Specific function: The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine [H]

COG id: COG0133

COG function: function code E; Tryptophan synthase beta chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpB family [H]

Homologues:

Organism=Escherichia coli, GI1787515, Length=384, Percent_Identity=56.5104166666667, Blast_Score=437, Evalue=1e-124,
Organism=Saccharomyces cerevisiae, GI6321412, Length=385, Percent_Identity=56.1038961038961, Blast_Score=447, Evalue=1e-126,

Paralogues:

None

Copy number: 360 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR006653
- InterPro:   IPR006654
- InterPro:   IPR023026 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.1.20 [H]

Molecular weight: Translated: 43763; Mature: 43763

Theoretical pI: Translated: 5.91; Mature: 5.91

Prosite motif: PS00168 TRP_SYNTHASE_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQPPKPNSFRSGPDEEGRFGIFGGRFVAETLMPLILDLQDEWARAKNDPAFKAELENLG
CCCCCCCCCCCCCCCCCCCEEEECHHHHHHHHHHHHHCCCHHHHHCCCCCHHHHHHHHHH
RHYIGRPSPLYFAERLTAELGGAKIYFKREELNHTGSHKINNCIGQILLAKRMGKTRIIA
HHHCCCCCHHHHHHHHHHHCCCEEEEEEHHHCCCCCCHHHHHHHHHHHHHHHCCCEEEEE
ETGAGQHGVASATVAARFGLPCVVYMGATDVERQAPNVFRMKLLGAEVKPVTAGHGTLKD
ECCCCCCCCHHHHHHHHCCCCEEEEECCCCHHHHCCCCEEHHHHCCCCCEEECCCCHHHH
AMNEALRDWVTNVDSTYYLIGTAAGPHPYPEMVRDFQAVIGEEAKQQMLEAEGRLPDLVV
HHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEE
AAVGGGSNAIGIFHPFLDDGGVRIVGVEAGGKGLDGDEHCASLTAGSPGVLHGNRTYLLQ
EEECCCCCEEEEEECCCCCCCEEEEEEECCCCCCCCHHHHHHHCCCCCCEEECCEEEEEE
DGDGQIKEGHSISAGLDYPGIGPEHAWLNDIGRVEYVPIMDHEALEAFQILTRLEGIIPA
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHCCC
LEPSHALAEVIKRAPKMGKDEIILMNLSGRGDKDIFTVGKILGMGQ
CCCHHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCC
>Mature Secondary Structure
MNQPPKPNSFRSGPDEEGRFGIFGGRFVAETLMPLILDLQDEWARAKNDPAFKAELENLG
CCCCCCCCCCCCCCCCCCCEEEECHHHHHHHHHHHHHCCCHHHHHCCCCCHHHHHHHHHH
RHYIGRPSPLYFAERLTAELGGAKIYFKREELNHTGSHKINNCIGQILLAKRMGKTRIIA
HHHCCCCCHHHHHHHHHHHCCCEEEEEEHHHCCCCCCHHHHHHHHHHHHHHHCCCEEEEE
ETGAGQHGVASATVAARFGLPCVVYMGATDVERQAPNVFRMKLLGAEVKPVTAGHGTLKD
ECCCCCCCCHHHHHHHHCCCCEEEEECCCCHHHHCCCCEEHHHHCCCCCEEECCCCHHHH
AMNEALRDWVTNVDSTYYLIGTAAGPHPYPEMVRDFQAVIGEEAKQQMLEAEGRLPDLVV
HHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEE
AAVGGGSNAIGIFHPFLDDGGVRIVGVEAGGKGLDGDEHCASLTAGSPGVLHGNRTYLLQ
EEECCCCCEEEEEECCCCCCCEEEEEEECCCCCCCCHHHHHHHCCCCCCEEECCEEEEEE
DGDGQIKEGHSISAGLDYPGIGPEHAWLNDIGRVEYVPIMDHEALEAFQILTRLEGIIPA
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHCCC
LEPSHALAEVIKRAPKMGKDEIILMNLSGRGDKDIFTVGKILGMGQ
CCCHHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA