Click here to switch to the map view.

The map label for this gene is holA

Identifier: 150398392

GI number: 150398392

Start: 3374425

End: 3375456

Strand: Direct

Name: holA

Synonym: Smed_3200

Alternate gene names: NA

Gene position: 3374425-3375456 (Clockwise)

Preceding gene: 150398391

Following gene: 150398401

Centisome position: 89.23

GC content: 62.5

Gene sequence:

>1032_bases
ATGAGCGAAATAAAGTCGCACGAGTTCGACAACTTTCTGCAGCGATCTGCGGCGGGCTACCGGCTTTTCCTGCTCTACGG
TCCGGACCGAGGACTTGTGTCCGAACGCGCAACAGCGCTCGCCGAAACTTTCGGGATCCCTCTCGACGATCCTTTTGCCG
TCGTCAAAATGGATGCCACGGGATTGCAGGGTGCCGGAAGCCTCCTTGACGAAGTGAATGCAATCGGCCTCTTCGGCGGC
GAGAAACTGGTGTGGATGCGTGGCGCCTCCACGGAGAAGGCGCTCATCGACGCCCTGCAGTTTCTCGCGTCAGATCCCCC
TGTCGGCGCCCGTCTCATCGTCGAAGCGGGAGATCTGAAGAAGGGAGCGGCGCTGAGGAAGGTTGGCGAGTCTTCCCGTT
CCGTCGCCTCAATCGCCTGCTACAGCGACGACGCCCGTGGCCTGCAAGCCCTTATAGACAAAGAACTTTCCGATGCGGGC
CTGCGCATCAGCCCGGCCGGGCGCGAGCGCCTCATGGACGCGCTCGGCGGCGACCGCATGGCCTCGCGCAACGAGCTTCG
CAAGCTAGCTCTCTATTGTCTCGGCAAGGATATGGTCGACGAGGTCGACGTCCTTGGGATCGTGGGCGACGCCAGCGCCA
TCTCGGTGGACGATGCGGTCGATGCGGTGCTGAAGGGCGATCCTGACGCGCTGTTGCATGCTATGAAGAAAATAACCACG
TCCAAGACGCCGCCGTTTCTCGTGCTTCAGGCTTGTCTCAGGCAGTTCCAGCAGCTCGACGTCATGCGCGCCGAAATGGA
TGCGAACCGCCAGCCTCCGGCCCAGGTGGTCGCGACCCTCGGGCGCGGCCTGCATTTCCGCCGCAAGCCGGTGGTCGAGG
CGGCGTTGAAGCACTGGACCGCACCGGCGATCCGGCGCGAATTGAGCCGCCTGCAATCAACGATCTACCAAAGCCGCAGC
CGCCAGAGCCTCGAGGAGAGCCTTGTGATACAGAATTTGCTGGCGATTACGATCCAGTCGGCTCGGCGCTGA

Upstream 100 bases:

>100_bases
TCGCGCCATCCGCGATGGCGAGAATCGCGCCGCGAAGGAACTGGCGGAGATTATCGGCGCCGATCTCGCAGCCGCCCTCG
GCCGCTGATCCGAACGTCAG

Downstream 100 bases:

>100_bases
GTTCCGGGACCCACCAACGCCGCCGCGCCACGCTTCAGCGCCGCTCGAGCAGCCTGCAGATCTCTTCCAGCTGATCGAGC
GTCTTATACGTGATCTTGAG

Product: DNA polymerase III subunit delta

Products: diphosphate; DNAn+1

Alternate protein names: DNA Polymerase III Delta Subunit

Number of amino acids: Translated: 343; Mature: 342

Protein sequence:

>343_residues
MSEIKSHEFDNFLQRSAAGYRLFLLYGPDRGLVSERATALAETFGIPLDDPFAVVKMDATGLQGAGSLLDEVNAIGLFGG
EKLVWMRGASTEKALIDALQFLASDPPVGARLIVEAGDLKKGAALRKVGESSRSVASIACYSDDARGLQALIDKELSDAG
LRISPAGRERLMDALGGDRMASRNELRKLALYCLGKDMVDEVDVLGIVGDASAISVDDAVDAVLKGDPDALLHAMKKITT
SKTPPFLVLQACLRQFQQLDVMRAEMDANRQPPAQVVATLGRGLHFRRKPVVEAALKHWTAPAIRRELSRLQSTIYQSRS
RQSLEESLVIQNLLAITIQSARR

Sequences:

>Translated_343_residues
MSEIKSHEFDNFLQRSAAGYRLFLLYGPDRGLVSERATALAETFGIPLDDPFAVVKMDATGLQGAGSLLDEVNAIGLFGG
EKLVWMRGASTEKALIDALQFLASDPPVGARLIVEAGDLKKGAALRKVGESSRSVASIACYSDDARGLQALIDKELSDAG
LRISPAGRERLMDALGGDRMASRNELRKLALYCLGKDMVDEVDVLGIVGDASAISVDDAVDAVLKGDPDALLHAMKKITT
SKTPPFLVLQACLRQFQQLDVMRAEMDANRQPPAQVVATLGRGLHFRRKPVVEAALKHWTAPAIRRELSRLQSTIYQSRS
RQSLEESLVIQNLLAITIQSARR
>Mature_342_residues
SEIKSHEFDNFLQRSAAGYRLFLLYGPDRGLVSERATALAETFGIPLDDPFAVVKMDATGLQGAGSLLDEVNAIGLFGGE
KLVWMRGASTEKALIDALQFLASDPPVGARLIVEAGDLKKGAALRKVGESSRSVASIACYSDDARGLQALIDKELSDAGL
RISPAGRERLMDALGGDRMASRNELRKLALYCLGKDMVDEVDVLGIVGDASAISVDDAVDAVLKGDPDALLHAMKKITTS
KTPPFLVLQACLRQFQQLDVMRAEMDANRQPPAQVVATLGRGLHFRRKPVVEAALKHWTAPAIRRELSRLQSTIYQSRSR
QSLEESLVIQNLLAITIQSARR

Specific function: Unknown

COG id: COG1466

COG function: function code L; DNA polymerase III, delta subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.7.7.7

Molecular weight: Translated: 37224; Mature: 37093

Theoretical pI: Translated: 7.51; Mature: 7.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEIKSHEFDNFLQRSAAGYRLFLLYGPDRGLVSERATALAETFGIPLDDPFAVVKMDAT
CCCCHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCEEEEECCC
GLQGAGSLLDEVNAIGLFGGEKLVWMRGASTEKALIDALQFLASDPPVGARLIVEAGDLK
CCCHHHHHHHHHHHHEECCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCC
KGAALRKVGESSRSVASIACYSDDARGLQALIDKELSDAGLRISPAGRERLMDALGGDRM
CCHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHCCCCEECCCHHHHHHHHHCCCCH
ASRNELRKLALYCLGKDMVDEVDVLGIVGDASAISVDDAVDAVLKGDPDALLHAMKKITT
HHHHHHHHHHHHHHCHHHHHHHHHHEEECCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHC
SKTPPFLVLQACLRQFQQLDVMRAEMDANRQPPAQVVATLGRGLHFRRKPVVEAALKHWT
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHCC
APAIRRELSRLQSTIYQSRSRQSLEESLVIQNLLAITIQSARR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SEIKSHEFDNFLQRSAAGYRLFLLYGPDRGLVSERATALAETFGIPLDDPFAVVKMDAT
CCCHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCEEEEECCC
GLQGAGSLLDEVNAIGLFGGEKLVWMRGASTEKALIDALQFLASDPPVGARLIVEAGDLK
CCCHHHHHHHHHHHHEECCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCC
KGAALRKVGESSRSVASIACYSDDARGLQALIDKELSDAGLRISPAGRERLMDALGGDRM
CCHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHCCCCEECCCHHHHHHHHHCCCCH
ASRNELRKLALYCLGKDMVDEVDVLGIVGDASAISVDDAVDAVLKGDPDALLHAMKKITT
HHHHHHHHHHHHHHCHHHHHHHHHHEEECCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHC
SKTPPFLVLQACLRQFQQLDVMRAEMDANRQPPAQVVATLGRGLHFRRKPVVEAALKHWT
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHCC
APAIRRELSRLQSTIYQSRSRQSLEESLVIQNLLAITIQSARR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: deoxynucleoside triphosphate; DNAn

Specific reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA