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The map label for this gene is aidB [H]

Identifier: 150396160

GI number: 150396160

Start: 1014994

End: 1016646

Strand: Direct

Name: aidB [H]

Synonym: Smed_0937

Alternate gene names: 150396160

Gene position: 1014994-1016646 (Clockwise)

Preceding gene: 150396149

Following gene: 150396162

Centisome position: 26.84

GC content: 63.58

Gene sequence:

>1653_bases
ATGAATCAGATGAACCGGACCGAGCAGAAACTTGCAGAACTGAACCAGCCTAAGCCCTGGTCCGGTGTCAATGCCTTTCG
CTCCGACCCGCTGGTGGTCGACATCACCTCCAGTATGCCGAAGTCGCTACGCGACGAGTTCGATGGACTTGGGCGTTACG
TGACTTCGCCCGAGGCACAGGAATTGGCCCGTATGGCCAATGAAGGGGTGCCGAAACTGAAGACGCACGGGCCCCGCGGC
GAGCGCCTCGACGTCGTCGAGTTCCATCCCGCCTGGCATGCGCTGATGCGCCGCTCCATGACGACGGGGCTGCATTCCTC
AGCCTGGGAGAACCTGCCCGATGAGCGCGGCCGTTCGCACAAGGTTCGGGCAATCCGCTTCTACCTGACGGCGCAGCTCG
AATGTGGCCATCTATGCCCGCTGACGATGACCAGCGCATCGGTCGCGGCGATCACGTCATCGCCCGCCGTCCAGAAGGAA
TGGGCGCCGAAGATCCTCTCGCGCAAATATGATTCGACCAACCGGCCGTGGATGCAGAAATCCGCCGTCACGATCGGCAT
GGGCATGACCGAGAAGCAGGGCGGCACGGACGTGCGCGCCAATACCTCCACGGCCGAACGCGTGGGCGAGGGCATTTATC
GCCTCACGGGACACAAATGGTTCATGTCCGCGCCGATGAGTGATGCCTTCGTCATGCTGGCGCAGACCCGGGAGGGGCTC
GGCTGCTTCCTGGTCCCGCGGCTGCTGGAGGACGGAGGGGCGAACGGCCTGCGTTTTCAGCGCCTGAAAGACAAGCTCGG
CAACCGGTCGAATGCATCCTCCGAGGTCGAGTTTTCGGATACTTTCGGCTTCCTGCTCGGAGCGCCGGATGCCGGCATTC
GCACGATCCTCGATATGGTGACGCTGACCCGGCTCGATTGTGCGCTCGCCTCGGCCGGTATGATGCGCGCGTCGCTCGCC
GAAGCGGTGCATCATACACGCGGTCGCAAGGTCTTCGGCAAGGCGCTTGTCAGCCAGCCCATGATGACCAGGGTGCTTGC
CGACATGGCTCTGGATGTCGCAGCTGCAAGCGCGCTGTCGTTCCGGCTTGCCGAAGCTTTCGACAATGCCCATAGCAGCG
CGGAGGATGCTGCCTACGCCCGTATCATGACGCCGGTTGCGAAATACTGGTGCTGCAAGATCGCCCCCGCGCTGATCTAC
GAGGCCATGGAGTGCATGGGCGGCAATGGCTATGTCGAGGAGCGGGCGCTTGCCCGCCACTACCGCGAAGCGCCGGTCAA
TGCGATATGGGAAGGGTCCGGCAACGTCATGGCGCTCGATGTCCTGCGGGTACTTTCGCGACGGAAGGAACTGTTCGAGC
AGCTCTTCGCAACGATCGGCCGCGATCTCGGTCCCGCCGGGCGAAAGACGATTGAAGTTCTGCGTGCCGCCATGTCGCTC
TGCGAGCGTGACGAAGGCGCCGCGCGGATGCTGGTCGAGCAACTTGCGCTGGCCGCGGCTGCCGCCGAGCTCTACAGGCT
CGGGGCGGGGCGCATCGCCGATGCGTTCCTGGAATCCCGCCTCGCCGCGGGCTGGCGCTCGACTTACGGCATGCTCGATT
CGCGTTTCGATTCGGCCTACGTCCTCGATTTGCTTTATCCGGCCGCAACATAG

Upstream 100 bases:

>100_bases
GAAAACCGGGCGGCAAGCGCCGGTCTCCCGTTTGGAAGAAAACTTGCGTCGCCCAGGCGTCCCTGTTTCGCGCCTCGGAA
ACTTGCGCTAGAACCGGCCC

Downstream 100 bases:

>100_bases
CCGGTAATGAGAAGCACGAGCGGTATGGTCACGAACGAAGCCGCGGTCTGGATCGTCGCGACGGAAGCGTAAAGCCCTGC
ATCACCTCCCATTTGCTTGG

Product: acyl-CoA dehydrogenase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 550; Mature: 550

Protein sequence:

>550_residues
MNQMNRTEQKLAELNQPKPWSGVNAFRSDPLVVDITSSMPKSLRDEFDGLGRYVTSPEAQELARMANEGVPKLKTHGPRG
ERLDVVEFHPAWHALMRRSMTTGLHSSAWENLPDERGRSHKVRAIRFYLTAQLECGHLCPLTMTSASVAAITSSPAVQKE
WAPKILSRKYDSTNRPWMQKSAVTIGMGMTEKQGGTDVRANTSTAERVGEGIYRLTGHKWFMSAPMSDAFVMLAQTREGL
GCFLVPRLLEDGGANGLRFQRLKDKLGNRSNASSEVEFSDTFGFLLGAPDAGIRTILDMVTLTRLDCALASAGMMRASLA
EAVHHTRGRKVFGKALVSQPMMTRVLADMALDVAAASALSFRLAEAFDNAHSSAEDAAYARIMTPVAKYWCCKIAPALIY
EAMECMGGNGYVEERALARHYREAPVNAIWEGSGNVMALDVLRVLSRRKELFEQLFATIGRDLGPAGRKTIEVLRAAMSL
CERDEGAARMLVEQLALAAAAAELYRLGAGRIADAFLESRLAAGWRSTYGMLDSRFDSAYVLDLLYPAAT

Sequences:

>Translated_550_residues
MNQMNRTEQKLAELNQPKPWSGVNAFRSDPLVVDITSSMPKSLRDEFDGLGRYVTSPEAQELARMANEGVPKLKTHGPRG
ERLDVVEFHPAWHALMRRSMTTGLHSSAWENLPDERGRSHKVRAIRFYLTAQLECGHLCPLTMTSASVAAITSSPAVQKE
WAPKILSRKYDSTNRPWMQKSAVTIGMGMTEKQGGTDVRANTSTAERVGEGIYRLTGHKWFMSAPMSDAFVMLAQTREGL
GCFLVPRLLEDGGANGLRFQRLKDKLGNRSNASSEVEFSDTFGFLLGAPDAGIRTILDMVTLTRLDCALASAGMMRASLA
EAVHHTRGRKVFGKALVSQPMMTRVLADMALDVAAASALSFRLAEAFDNAHSSAEDAAYARIMTPVAKYWCCKIAPALIY
EAMECMGGNGYVEERALARHYREAPVNAIWEGSGNVMALDVLRVLSRRKELFEQLFATIGRDLGPAGRKTIEVLRAAMSL
CERDEGAARMLVEQLALAAAAAELYRLGAGRIADAFLESRLAAGWRSTYGMLDSRFDSAYVLDLLYPAAT
>Mature_550_residues
MNQMNRTEQKLAELNQPKPWSGVNAFRSDPLVVDITSSMPKSLRDEFDGLGRYVTSPEAQELARMANEGVPKLKTHGPRG
ERLDVVEFHPAWHALMRRSMTTGLHSSAWENLPDERGRSHKVRAIRFYLTAQLECGHLCPLTMTSASVAAITSSPAVQKE
WAPKILSRKYDSTNRPWMQKSAVTIGMGMTEKQGGTDVRANTSTAERVGEGIYRLTGHKWFMSAPMSDAFVMLAQTREGL
GCFLVPRLLEDGGANGLRFQRLKDKLGNRSNASSEVEFSDTFGFLLGAPDAGIRTILDMVTLTRLDCALASAGMMRASLA
EAVHHTRGRKVFGKALVSQPMMTRVLADMALDVAAASALSFRLAEAFDNAHSSAEDAAYARIMTPVAKYWCCKIAPALIY
EAMECMGGNGYVEERALARHYREAPVNAIWEGSGNVMALDVLRVLSRRKELFEQLFATIGRDLGPAGRKTIEVLRAAMSL
CERDEGAARMLVEQLALAAAAAELYRLGAGRIADAFLESRLAAGWRSTYGMLDSRFDSAYVLDLLYPAAT

Specific function: May help to prevent alkylation damage by protecting DNA and destroying alkylating agents [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=262, Percent_Identity=29.7709923664122, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI226958412, Length=307, Percent_Identity=25.4071661237785, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI226958414, Length=307, Percent_Identity=25.4071661237785, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI7656849, Length=265, Percent_Identity=28.3018867924528, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI4557235, Length=377, Percent_Identity=24.4031830238727, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI4501859, Length=252, Percent_Identity=23.8095238095238, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI76496475, Length=377, Percent_Identity=24.4031830238727, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI4501857, Length=276, Percent_Identity=25, Blast_Score=77, Evalue=5e-14,
Organism=Homo sapiens, GI4557231, Length=268, Percent_Identity=26.865671641791, Blast_Score=76, Evalue=9e-14,
Organism=Homo sapiens, GI187960098, Length=268, Percent_Identity=26.865671641791, Blast_Score=76, Evalue=1e-13,
Organism=Escherichia coli, GI87082384, Length=510, Percent_Identity=45.0980392156863, Blast_Score=417, Evalue=1e-118,
Organism=Escherichia coli, GI1786223, Length=264, Percent_Identity=23.4848484848485, Blast_Score=63, Evalue=4e-11,
Organism=Escherichia coli, GI87081958, Length=262, Percent_Identity=23.6641221374046, Blast_Score=63, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI86563383, Length=451, Percent_Identity=32.1507760532151, Blast_Score=186, Evalue=3e-47,
Organism=Caenorhabditis elegans, GI86563381, Length=451, Percent_Identity=32.1507760532151, Blast_Score=186, Evalue=3e-47,
Organism=Caenorhabditis elegans, GI17538396, Length=305, Percent_Identity=25.5737704918033, Blast_Score=88, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17569725, Length=269, Percent_Identity=24.5353159851301, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17508101, Length=287, Percent_Identity=22.9965156794425, Blast_Score=81, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17506239, Length=266, Percent_Identity=22.1804511278195, Blast_Score=78, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17534899, Length=269, Percent_Identity=23.7918215613383, Blast_Score=76, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17533517, Length=262, Percent_Identity=24.8091603053435, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71985184, Length=266, Percent_Identity=23.3082706766917, Blast_Score=69, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17570075, Length=293, Percent_Identity=23.5494880546075, Blast_Score=66, Evalue=4e-11,
Organism=Drosophila melanogaster, GI21356377, Length=262, Percent_Identity=26.7175572519084, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24646207, Length=285, Percent_Identity=25.2631578947368, Blast_Score=86, Evalue=5e-17,
Organism=Drosophila melanogaster, GI21355753, Length=296, Percent_Identity=23.9864864864865, Blast_Score=82, Evalue=8e-16,
Organism=Drosophila melanogaster, GI24660351, Length=327, Percent_Identity=24.7706422018349, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24666513, Length=263, Percent_Identity=21.2927756653992, Blast_Score=73, Evalue=6e-13,
Organism=Drosophila melanogaster, GI281363737, Length=302, Percent_Identity=21.523178807947, Blast_Score=72, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M [H]

EC number: NA

Molecular weight: Translated: 60442; Mature: 60442

Theoretical pI: Translated: 8.54; Mature: 8.54

Prosite motif: PS00072 ACYL_COA_DH_1 ; PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQMNRTEQKLAELNQPKPWSGVNAFRSDPLVVDITSSMPKSLRDEFDGLGRYVTSPEAQ
CCCCHHHHHHHHHCCCCCCCCCCHHHCCCCEEEEECHHCCHHHHHHHHHHCCCCCCCCHH
ELARMANEGVPKLKTHGPRGERLDVVEFHPAWHALMRRSMTTGLHSSAWENLPDERGRSH
HHHHHHHCCCCCCCCCCCCCCCCCEEEECHHHHHHHHHHHHCCCHHHHHHCCCHHCCCCC
KVRAIRFYLTAQLECGHLCPLTMTSASVAAITSSPAVQKEWAPKILSRKYDSTNRPWMQK
CCEEEEEEEEEECCCCCCCCCEECCCHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCHHH
SAVTIGMGMTEKQGGTDVRANTSTAERVGEGIYRLTGHKWFMSAPMSDAFVMLAQTREGL
CCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHCCCC
GCFLVPRLLEDGGANGLRFQRLKDKLGNRSNASSEVEFSDTFGFLLGAPDAGIRTILDMV
CHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCEEEHHHCHHHCCCCCHHHHHHHHHH
TLTRLDCALASAGMMRASLAEAVHHTRGRKVFGKALVSQPMMTRVLADMALDVAAASALS
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
FRLAEAFDNAHSSAEDAAYARIMTPVAKYWCCKIAPALIYEAMECMGGNGYVEERALARH
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
YREAPVNAIWEGSGNVMALDVLRVLSRRKELFEQLFATIGRDLGPAGRKTIEVLRAAMSL
HHHCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
CERDEGAARMLVEQLALAAAAAELYRLGAGRIADAFLESRLAAGWRSTYGMLDSRFDSAY
HHCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
VLDLLYPAAT
HHHHHHCCCC
>Mature Secondary Structure
MNQMNRTEQKLAELNQPKPWSGVNAFRSDPLVVDITSSMPKSLRDEFDGLGRYVTSPEAQ
CCCCHHHHHHHHHCCCCCCCCCCHHHCCCCEEEEECHHCCHHHHHHHHHHCCCCCCCCHH
ELARMANEGVPKLKTHGPRGERLDVVEFHPAWHALMRRSMTTGLHSSAWENLPDERGRSH
HHHHHHHCCCCCCCCCCCCCCCCCEEEECHHHHHHHHHHHHCCCHHHHHHCCCHHCCCCC
KVRAIRFYLTAQLECGHLCPLTMTSASVAAITSSPAVQKEWAPKILSRKYDSTNRPWMQK
CCEEEEEEEEEECCCCCCCCCEECCCHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCHHH
SAVTIGMGMTEKQGGTDVRANTSTAERVGEGIYRLTGHKWFMSAPMSDAFVMLAQTREGL
CCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHCCCC
GCFLVPRLLEDGGANGLRFQRLKDKLGNRSNASSEVEFSDTFGFLLGAPDAGIRTILDMV
CHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCEEEHHHCHHHCCCCCHHHHHHHHHH
TLTRLDCALASAGMMRASLAEAVHHTRGRKVFGKALVSQPMMTRVLADMALDVAAASALS
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
FRLAEAFDNAHSSAEDAAYARIMTPVAKYWCCKIAPALIYEAMECMGGNGYVEERALARH
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
YREAPVNAIWEGSGNVMALDVLRVLSRRKELFEQLFATIGRDLGPAGRKTIEVLRAAMSL
HHHCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
CERDEGAARMLVEQLALAAAAAELYRLGAGRIADAFLESRLAAGWRSTYGMLDSRFDSAY
HHCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
VLDLLYPAAT
HHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7961409; 7610040; 9278503 [H]