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The map label for this gene is nuoE1 [H]

Identifier: 150396116

GI number: 150396116

Start: 963468

End: 964289

Strand: Direct

Name: nuoE1 [H]

Synonym: Smed_0893

Alternate gene names: 150396116

Gene position: 963468-964289 (Clockwise)

Preceding gene: 150396115

Following gene: 150396117

Centisome position: 25.48

GC content: 62.77

Gene sequence:

>822_bases
ATGTCCGTTCGTCGACTAGCCGAAGACACTGTCCAGCCAGCGACCTTCGCGTTCAGCAAGGAAAACGCTGCCTGGGCCGA
GGCAACGATCAAGAAATACCCCGAGGGCCGCGAGCAGTCGGCGGTCATTCCCCTGCTGATGCGTGCTCAGGAGCAGGATG
GCTGGGTTACGCGCGCGGCGATCGAGAAGATCGCAGACATGCTCGGCATGGCCTATATCCGCGTCCTCGAAGTCGCCACC
TTCTATACCCAGTTCCAGCTGCAGCCGGTCGGGACGCGTGCGCATGTCCAGGTCTGTGGCACGACGCCCTGCATGCTGCG
CGGCGCCGAGGATCTGATCAAGGTCTGCAAGAAGAAGATCGCCGGCGATCCGTTCACGCTCAATGAAGGCGGCACGCTTT
CGTGGGAAGAGGTCGAATGTCAGGGCGCCTGCGTCAATGCGCCGATGGTCATGATCTTCAAGGACACGTTCGAGGATCTG
ACGCCGGAGCGGCTTGAGGAGATCATCGACCTCTTCGAGGCCGGCAAGGGGACGGACGTCGTGCCGGGCCCGCAGATCGA
CCGCATCTATTCCGCGCCGATCGGCGGTTTGACGACCTTGCAGGCGCCTGCGGAAGAGAAGAAGCCCGCCCGCGCAAGCA
AGGCGAAGGAAGAACAGGCGGTGAGCGTGCCGCCTTCGAATGCGGCGAAGCCATCGACCGTCGCGGACATTACCAATCCG
ACGTTGAAGACCCCGGCCACCGCGAAGAAAGCGGCGGCGAAGAACGTCAAGGTTGAGGGCGAAACGGTCGACAAGTCGAA
GCCCGCGAAGAAGCCGCGGTGA

Upstream 100 bases:

>100_bases
ATCGTGTTTTTGCAGAAAGACCAGTCAGCCTATGCCTGCGAATTTGTCTCGCTGACGAAATCGCGGTGCGGTTCGATTAA
CTGATAAGGTGTCCACTAGA

Downstream 100 bases:

>100_bases
AGAGGTGATACCCCATGCTTAAAGACGAAGATCGCATCTTTACCAACATCTACGGCCTCATGGACAAGTCGCTCAAGGGC
GCGATGGCGCGAGGCCATTG

Product: NADH dehydrogenase subunit E

Products: NA

Alternate protein names: NADH dehydrogenase I subunit E 1; NDH-1 subunit E 1 [H]

Number of amino acids: Translated: 273; Mature: 272

Protein sequence:

>273_residues
MSVRRLAEDTVQPATFAFSKENAAWAEATIKKYPEGREQSAVIPLLMRAQEQDGWVTRAAIEKIADMLGMAYIRVLEVAT
FYTQFQLQPVGTRAHVQVCGTTPCMLRGAEDLIKVCKKKIAGDPFTLNEGGTLSWEEVECQGACVNAPMVMIFKDTFEDL
TPERLEEIIDLFEAGKGTDVVPGPQIDRIYSAPIGGLTTLQAPAEEKKPARASKAKEEQAVSVPPSNAAKPSTVADITNP
TLKTPATAKKAAAKNVKVEGETVDKSKPAKKPR

Sequences:

>Translated_273_residues
MSVRRLAEDTVQPATFAFSKENAAWAEATIKKYPEGREQSAVIPLLMRAQEQDGWVTRAAIEKIADMLGMAYIRVLEVAT
FYTQFQLQPVGTRAHVQVCGTTPCMLRGAEDLIKVCKKKIAGDPFTLNEGGTLSWEEVECQGACVNAPMVMIFKDTFEDL
TPERLEEIIDLFEAGKGTDVVPGPQIDRIYSAPIGGLTTLQAPAEEKKPARASKAKEEQAVSVPPSNAAKPSTVADITNP
TLKTPATAKKAAAKNVKVEGETVDKSKPAKKPR
>Mature_272_residues
SVRRLAEDTVQPATFAFSKENAAWAEATIKKYPEGREQSAVIPLLMRAQEQDGWVTRAAIEKIADMLGMAYIRVLEVATF
YTQFQLQPVGTRAHVQVCGTTPCMLRGAEDLIKVCKKKIAGDPFTLNEGGTLSWEEVECQGACVNAPMVMIFKDTFEDLT
PERLEEIIDLFEAGKGTDVVPGPQIDRIYSAPIGGLTTLQAPAEEKKPARASKAKEEQAVSVPPSNAAKPSTVADITNPT
LKTPATAKKAAAKNVKVEGETVDKSKPAKKPR

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1905

COG function: function code C; NADH:ubiquinone oxidoreductase 24 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 24 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI222080062, Length=188, Percent_Identity=45.7446808510638, Blast_Score=165, Evalue=4e-41,
Organism=Escherichia coli, GI1788621, Length=163, Percent_Identity=34.3558282208589, Blast_Score=80, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17561328, Length=201, Percent_Identity=42.7860696517413, Blast_Score=162, Evalue=1e-40,
Organism=Drosophila melanogaster, GI18859877, Length=185, Percent_Identity=44.3243243243243, Blast_Score=159, Evalue=1e-39,
Organism=Drosophila melanogaster, GI21355353, Length=188, Percent_Identity=36.1702127659575, Blast_Score=122, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002023
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF01257 Complex1_24kDa [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 29616; Mature: 29485

Theoretical pI: Translated: 7.10; Mature: 7.10

Prosite motif: PS01099 COMPLEX1_24K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVRRLAEDTVQPATFAFSKENAAWAEATIKKYPEGREQSAVIPLLMRAQEQDGWVTRAA
CCHHHHHHHHCCCHHEEECCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCHHHHHH
IEKIADMLGMAYIRVLEVATFYTQFQLQPVGTRAHVQVCGTTPCMLRGAEDLIKVCKKKI
HHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCEEEEEECCCCHHHHCCHHHHHHHHHHHH
AGDPFTLNEGGTLSWEEVECQGACVNAPMVMIFKDTFEDLTPERLEEIIDLFEAGKGTDV
CCCCEEECCCCCCCHHHHCCCCEECCCCEEEEEHHHHHCCCHHHHHHHHHHHHCCCCCCC
VPGPQIDRIYSAPIGGLTTLQAPAEEKKPARASKAKEEQAVSVPPSNAAKPSTVADITNP
CCCCCHHHHHCCCCCCCEECCCCCHHCCCCHHHHHHHHCCCCCCCCCCCCCCCHHHCCCC
TLKTPATAKKAAAKNVKVEGETVDKSKPAKKPR
CCCCCCHHHHHHHCCCEECCCCCCCCCCCCCCC
>Mature Secondary Structure 
SVRRLAEDTVQPATFAFSKENAAWAEATIKKYPEGREQSAVIPLLMRAQEQDGWVTRAA
CHHHHHHHHCCCHHEEECCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCHHHHHH
IEKIADMLGMAYIRVLEVATFYTQFQLQPVGTRAHVQVCGTTPCMLRGAEDLIKVCKKKI
HHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCEEEEEECCCCHHHHCCHHHHHHHHHHHH
AGDPFTLNEGGTLSWEEVECQGACVNAPMVMIFKDTFEDLTPERLEEIIDLFEAGKGTDV
CCCCEEECCCCCCCHHHHCCCCEECCCCEEEEEHHHHHCCCHHHHHHHHHHHHCCCCCCC
VPGPQIDRIYSAPIGGLTTLQAPAEEKKPARASKAKEEQAVSVPPSNAAKPSTVADITNP
CCCCCHHHHHCCCCCCCEECCCCCHHCCCCHHHHHHHHCCCCCCCCCCCCCCCHHHCCCC
TLKTPATAKKAAAKNVKVEGETVDKSKPAKKPR
CCCCCCHHHHHHHCCCEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]