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The map label for this gene is ydjJ [C]

Identifier: 150396072

GI number: 150396072

Start: 906704

End: 907738

Strand: Direct

Name: ydjJ [C]

Synonym: Smed_0849

Alternate gene names: 150396072

Gene position: 906704-907738 (Clockwise)

Preceding gene: 150396070

Following gene: 150396077

Centisome position: 23.97

GC content: 61.16

Gene sequence:

>1035_bases
ATGCCCAGAGCACTCGTCCTAGAGCAAATCCGGAAACTCTCGCTGCGCGATATCGACCTGCCGCAGGAAGTCGGACCCCA
CGACGTCCGCATCAAGATTCACACGGTCGGGATATGCGGGTCGGACGTGCATTATTACACGCACGGCCGGATAGGGCCTT
TTGTGGTGAATGCGCCGATGGTACTCGGGCATGAGGCGGCTGGCGTCGTCGTCGAAACCGGTAAGGACGTGACGCATCTC
AAGGCAGGGGATCGCGTGTGCATGGAGCCCGGAATTCCGGACGCGAATTCGCGCGCCAGTCGTCTTGGCCTTTACAATAT
CGACCCGGCTGTGACGTTTTGGGCGACGCCTCCTGTCCATGGCGTCCTGACTCCGCACGTCGTCCACTCGGCGAATTACA
CCTATAAGCTGCCGGACAAAGTCAGTTTCGCAGAAGGGGCGATGGTGGAGCCGTTTGCCGTCGGCATGCAGGCGGCGCAA
AAGGCGAAGATTGCTCCCGGCGATACTGCCGTGGTCACCGGCGCCGGGCCGATCGGCATCATGGTGGCGATCGCGGCGCT
CGCCGGAGGGTGCGCGCGGGTGATTGTTGCCGATTTCGCGCAACCGAAGCTAGACATTGCGGCGCAATACCAGGGCATCC
TGCCGATCAACATCGGCAAACGCGACCTCGCGGAGGAAGTGAAGCAGCTCACCGAGGGCTGGGGCGCCGATGTGGTGTTC
GAATGCTCAGGTTCGCCGAAGGCATGGGAGACATTGCTCGATCTTCCCCGGCCAGGCGGTGCCGTCGTTGCTGTGGGACT
CCCGGTCGAACCGGTTGGTCTGGATATATCCACCGCATCGACGAAGGAAATCCGGTTTGAGACGGTATTTCGCTATGCCC
ATCAATATGACCGCGCAATCGCTTTGATGGGATCTGGGCGCGTCGACCTGAAGCCGCTCATCACCGAGACGTTTCCGTTC
GAAGAAAGTGTCGCGGCTTTCGATCGCGCGGCGGAGGGTAGGCCGGGTGATGTGAAGCTGCAGATCACGCTGTAG

Upstream 100 bases:

>100_bases
GCCTTGACCATCTACCCGCGGAGAGTGCAGAAAATCAGCGGGGCCATCGTCGATCGCAACGGCGAACCTTGCGGAGTCCG
ACGGCCATCGAGGAGAAATC

Downstream 100 bases:

>100_bases
GGTTCACGGAACTCCTCCCGTGACGCGTCTTTCGGTGCGGGAGGAGTTTCTTCAGCTCAAGGACTTGGTCTGGCTGGTTC
CTGTGACGAGCACGGGAATG

Product: alcohol dehydrogenase

Products: NA

Alternate protein names: Xylitol dehydrogenase; XDH [H]

Number of amino acids: Translated: 344; Mature: 343

Protein sequence:

>344_residues
MPRALVLEQIRKLSLRDIDLPQEVGPHDVRIKIHTVGICGSDVHYYTHGRIGPFVVNAPMVLGHEAAGVVVETGKDVTHL
KAGDRVCMEPGIPDANSRASRLGLYNIDPAVTFWATPPVHGVLTPHVVHSANYTYKLPDKVSFAEGAMVEPFAVGMQAAQ
KAKIAPGDTAVVTGAGPIGIMVAIAALAGGCARVIVADFAQPKLDIAAQYQGILPINIGKRDLAEEVKQLTEGWGADVVF
ECSGSPKAWETLLDLPRPGGAVVAVGLPVEPVGLDISTASTKEIRFETVFRYAHQYDRAIALMGSGRVDLKPLITETFPF
EESVAAFDRAAEGRPGDVKLQITL

Sequences:

>Translated_344_residues
MPRALVLEQIRKLSLRDIDLPQEVGPHDVRIKIHTVGICGSDVHYYTHGRIGPFVVNAPMVLGHEAAGVVVETGKDVTHL
KAGDRVCMEPGIPDANSRASRLGLYNIDPAVTFWATPPVHGVLTPHVVHSANYTYKLPDKVSFAEGAMVEPFAVGMQAAQ
KAKIAPGDTAVVTGAGPIGIMVAIAALAGGCARVIVADFAQPKLDIAAQYQGILPINIGKRDLAEEVKQLTEGWGADVVF
ECSGSPKAWETLLDLPRPGGAVVAVGLPVEPVGLDISTASTKEIRFETVFRYAHQYDRAIALMGSGRVDLKPLITETFPF
EESVAAFDRAAEGRPGDVKLQITL
>Mature_343_residues
PRALVLEQIRKLSLRDIDLPQEVGPHDVRIKIHTVGICGSDVHYYTHGRIGPFVVNAPMVLGHEAAGVVVETGKDVTHLK
AGDRVCMEPGIPDANSRASRLGLYNIDPAVTFWATPPVHGVLTPHVVHSANYTYKLPDKVSFAEGAMVEPFAVGMQAAQK
AKIAPGDTAVVTGAGPIGIMVAIAALAGGCARVIVADFAQPKLDIAAQYQGILPINIGKRDLAEEVKQLTEGWGADVVFE
CSGSPKAWETLLDLPRPGGAVVAVGLPVEPVGLDISTASTKEIRFETVFRYAHQYDRAIALMGSGRVDLKPLITETFPFE
ESVAAFDRAAEGRPGDVKLQITL

Specific function: Unknown

COG id: COG1063

COG function: function code ER; Threonine dehydrogenase and related Zn-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI156627571, Length=332, Percent_Identity=39.7590361445783, Blast_Score=255, Evalue=4e-68,
Organism=Homo sapiens, GI4501933, Length=375, Percent_Identity=28.8, Blast_Score=101, Evalue=9e-22,
Organism=Homo sapiens, GI71743840, Length=372, Percent_Identity=27.4193548387097, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI262073058, Length=372, Percent_Identity=27.4193548387097, Blast_Score=81, Evalue=2e-15,
Organism=Escherichia coli, GI1788073, Length=333, Percent_Identity=37.8378378378378, Blast_Score=207, Evalue=8e-55,
Organism=Escherichia coli, GI1790045, Length=330, Percent_Identity=30.9090909090909, Blast_Score=148, Evalue=5e-37,
Organism=Escherichia coli, GI1790718, Length=323, Percent_Identity=28.4829721362229, Blast_Score=134, Evalue=9e-33,
Organism=Escherichia coli, GI1788075, Length=331, Percent_Identity=27.7945619335347, Blast_Score=108, Evalue=5e-25,
Organism=Escherichia coli, GI1787863, Length=346, Percent_Identity=26.0115606936416, Blast_Score=108, Evalue=8e-25,
Organism=Escherichia coli, GI226510992, Length=331, Percent_Identity=30.8157099697885, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1788407, Length=340, Percent_Identity=25.8823529411765, Blast_Score=95, Evalue=8e-21,
Organism=Escherichia coli, GI87081918, Length=255, Percent_Identity=29.8039215686275, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1786552, Length=366, Percent_Identity=28.9617486338798, Blast_Score=63, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17562876, Length=330, Percent_Identity=40.3030303030303, Blast_Score=268, Evalue=4e-72,
Organism=Caenorhabditis elegans, GI17562878, Length=314, Percent_Identity=42.6751592356688, Blast_Score=239, Evalue=1e-63,
Organism=Saccharomyces cerevisiae, GI6323099, Length=345, Percent_Identity=41.4492753623188, Blast_Score=270, Evalue=3e-73,
Organism=Saccharomyces cerevisiae, GI6322619, Length=332, Percent_Identity=39.4578313253012, Blast_Score=243, Evalue=4e-65,
Organism=Saccharomyces cerevisiae, GI6319955, Length=332, Percent_Identity=39.4578313253012, Blast_Score=243, Evalue=4e-65,
Organism=Saccharomyces cerevisiae, GI6319257, Length=325, Percent_Identity=26.4615384615385, Blast_Score=109, Evalue=7e-25,
Organism=Saccharomyces cerevisiae, GI6319258, Length=367, Percent_Identity=26.158038147139, Blast_Score=94, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6323729, Length=284, Percent_Identity=29.2253521126761, Blast_Score=70, Evalue=3e-13,
Organism=Drosophila melanogaster, GI17137530, Length=340, Percent_Identity=38.8235294117647, Blast_Score=241, Evalue=4e-64,
Organism=Drosophila melanogaster, GI17737897, Length=340, Percent_Identity=38.8235294117647, Blast_Score=235, Evalue=3e-62,
Organism=Drosophila melanogaster, GI45551930, Length=309, Percent_Identity=31.3915857605178, Blast_Score=141, Evalue=6e-34,
Organism=Drosophila melanogaster, GI45550770, Length=309, Percent_Identity=31.3915857605178, Blast_Score=141, Evalue=6e-34,
Organism=Drosophila melanogaster, GI221457811, Length=309, Percent_Identity=31.3915857605178, Blast_Score=141, Evalue=7e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.1.1.9 [H]

Molecular weight: Translated: 36677; Mature: 36545

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: PS00059 ADH_ZINC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRALVLEQIRKLSLRDIDLPQEVGPHDVRIKIHTVGICGSDVHYYTHGRIGPFVVNAPM
CCHHHHHHHHHHCCCCCCCCCHHCCCCEEEEEEEEEEEECCCCEEEECCCCCCEEEECCE
VLGHEAAGVVVETGKDVTHLKAGDRVCMEPGIPDANSRASRLGLYNIDPAVTFWATPPVH
EECCCCCCEEEECCCCEEEECCCCEEEECCCCCCCCCHHHHCCEEECCCCEEEEECCCCC
GVLTPHVVHSANYTYKLPDKVSFAEGAMVEPFAVGMQAAQKAKIAPGDTAVVTGAGPIGI
CCCCCEEEECCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEECCCHHHH
MVAIAALAGGCARVIVADFAQPKLDIAAQYQGILPINIGKRDLAEEVKQLTEGWGADVVF
HHHHHHHHCCHHEEHHHHCCCCCEEEHHHCCCEEEEECCHHHHHHHHHHHHCCCCCCEEE
ECSGSPKAWETLLDLPRPGGAVVAVGLPVEPVGLDISTASTKEIRFETVFRYAHQYDRAI
EECCCCHHHHHHHCCCCCCCEEEEEECCCCCCCEEEECCCCCHHHHHHHHHHHHHHCCEE
ALMGSGRVDLKPLITETFPFEESVAAFDRAAEGRPGDVKLQITL
EEECCCCCCCCHHHCCCCCCHHHHHHHHHHCCCCCCCEEEEEEC
>Mature Secondary Structure 
PRALVLEQIRKLSLRDIDLPQEVGPHDVRIKIHTVGICGSDVHYYTHGRIGPFVVNAPM
CHHHHHHHHHHCCCCCCCCCHHCCCCEEEEEEEEEEEECCCCEEEECCCCCCEEEECCE
VLGHEAAGVVVETGKDVTHLKAGDRVCMEPGIPDANSRASRLGLYNIDPAVTFWATPPVH
EECCCCCCEEEECCCCEEEECCCCEEEECCCCCCCCCHHHHCCEEECCCCEEEEECCCCC
GVLTPHVVHSANYTYKLPDKVSFAEGAMVEPFAVGMQAAQKAKIAPGDTAVVTGAGPIGI
CCCCCEEEECCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEECCCHHHH
MVAIAALAGGCARVIVADFAQPKLDIAAQYQGILPINIGKRDLAEEVKQLTEGWGADVVF
HHHHHHHHCCHHEEHHHHCCCCCEEEHHHCCCEEEEECCHHHHHHHHHHHHCCCCCCEEE
ECSGSPKAWETLLDLPRPGGAVVAVGLPVEPVGLDISTASTKEIRFETVFRYAHQYDRAI
EECCCCHHHHHHHCCCCCCCEEEEEECCCCCCCEEEECCCCCHHHHHHHHHHHHHHCCEE
ALMGSGRVDLKPLITETFPFEESVAAFDRAAEGRPGDVKLQITL
EEECCCCCCCCHHHCCCCCCHHHHHHHHHHCCCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]