Click here to switch to the map view.

The map label for this gene is nudK [H]

Identifier: 150396014

GI number: 150396014

Start: 847968

End: 848564

Strand: Direct

Name: nudK [H]

Synonym: Smed_0790

Alternate gene names: 150396014

Gene position: 847968-848564 (Clockwise)

Preceding gene: 150396013

Following gene: 150396017

Centisome position: 22.42

GC content: 60.64

Gene sequence:

>597_bases
ATGGTCAAGAATACAGACCCGCGCTTCCGGATCATCGACCGCAAAACGCTCTGGGATGGTTTCATCAATCTCGAGCAGAT
CACGCTCGAACAGGAAATGTCCGACGGCAGCACCGCCCGCCTGGTGCGTGAAGTGCACGACCACGGCCGTGCCGCAACGA
TCCTGCTCTTTGACCCGGAGCGGCAGGTGGTGGTTCTCGTTCGCCAGCTTCGCCTTCCCGTCTTCCTGCAGGGGGAGACG
GGATACCTTCTCGAGGCACCGGCCGGTCTCCTTGACGGCGAAGCCCCGGAAGTTGCGATCTGCCGCGAGGCGATGGAGGA
AACCGGCTACCGAATCGAGAGCGCAATGCACCTCTTCGATGCCTATATGAGCCCCGGTTCGATTACGGAGCGCACGAGCT
TCTTCGTCGGTCTCGTCGATATTTCCAGGAAGGTCGCGGCCGGCGGCGGACTTGCGCAAGAGGGCGAGGACATCGAAGTG
CTGGAAATAGCCTTCGAGGAAGCAGTCGCGAAGATCGGCACCGGCGAGATCTGCGACGCCAAGACCATCATGCTGCTGCA
ATGGGCCATGCTCAACAGGGACTCTCTTTCGAAGTAG

Upstream 100 bases:

>100_bases
CGGTGCCGATGCCGTCGCACCCTATGGCGGCGCTGCATTCCATGACAACCGGGTCTGGATGCGCCGGGCCTGACCGGTCC
ACTCTTCTGAAGGATTCTCC

Downstream 100 bases:

>100_bases
CGCTCCGGGCAATTCGCGTTGAGGTCCACGGTGGCGAGCGTGGGGAAGCGACGAGCTTTCCTACATCACGGGTGAAATCA
GCATACCCGTTGCCTCTCGA

Product: NUDIX hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 198; Mature: 198

Protein sequence:

>198_residues
MVKNTDPRFRIIDRKTLWDGFINLEQITLEQEMSDGSTARLVREVHDHGRAATILLFDPERQVVVLVRQLRLPVFLQGET
GYLLEAPAGLLDGEAPEVAICREAMEETGYRIESAMHLFDAYMSPGSITERTSFFVGLVDISRKVAAGGGLAQEGEDIEV
LEIAFEEAVAKIGTGEICDAKTIMLLQWAMLNRDSLSK

Sequences:

>Translated_198_residues
MVKNTDPRFRIIDRKTLWDGFINLEQITLEQEMSDGSTARLVREVHDHGRAATILLFDPERQVVVLVRQLRLPVFLQGET
GYLLEAPAGLLDGEAPEVAICREAMEETGYRIESAMHLFDAYMSPGSITERTSFFVGLVDISRKVAAGGGLAQEGEDIEV
LEIAFEEAVAKIGTGEICDAKTIMLLQWAMLNRDSLSK
>Mature_198_residues
MVKNTDPRFRIIDRKTLWDGFINLEQITLEQEMSDGSTARLVREVHDHGRAATILLFDPERQVVVLVRQLRLPVFLQGET
GYLLEAPAGLLDGEAPEVAICREAMEETGYRIESAMHLFDAYMSPGSITERTSFFVGLVDISRKVAAGGGLAQEGEDIEV
LEIAFEEAVAKIGTGEICDAKTIMLLQWAMLNRDSLSK

Specific function: Catalyzes the hydrolysis of GDP-mannose [H]

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Escherichia coli, GI1788810, Length=179, Percent_Identity=45.8100558659218, Blast_Score=158, Evalue=3e-40,
Organism=Escherichia coli, GI1789412, Length=191, Percent_Identity=37.17277486911, Blast_Score=112, Evalue=2e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004385
- InterPro:   IPR000086
- InterPro:   IPR015797 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: NA

Molecular weight: Translated: 22014; Mature: 22014

Theoretical pI: Translated: 4.40; Mature: 4.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKNTDPRFRIIDRKTLWDGFINLEQITLEQEMSDGSTARLVREVHDHGRAATILLFDPE
CCCCCCCCEEEEECHHHHHHHCCHHHEEHHHHCCCCHHHHHHHHHHHCCCEEEEEEECCC
RQVVVLVRQLRLPVFLQGETGYLLEAPAGLLDGEAPEVAICREAMEETGYRIESAMHLFD
CHHHHHHHHHCCCEEEECCCCEEEECCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHH
AYMSPGSITERTSFFVGLVDISRKVAAGGGLAQEGEDIEVLEIAFEEAVAKIGTGEICDA
HHCCCCCCCHHHHHEEEHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCH
KTIMLLQWAMLNRDSLSK
HHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MVKNTDPRFRIIDRKTLWDGFINLEQITLEQEMSDGSTARLVREVHDHGRAATILLFDPE
CCCCCCCCEEEEECHHHHHHHCCHHHEEHHHHCCCCHHHHHHHHHHHCCCEEEEEEECCC
RQVVVLVRQLRLPVFLQGETGYLLEAPAGLLDGEAPEVAICREAMEETGYRIESAMHLFD
CHHHHHHHHHCCCEEEECCCCEEEECCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHH
AYMSPGSITERTSFFVGLVDISRKVAAGGGLAQEGEDIEVLEIAFEEAVAKIGTGEICDA
HHCCCCCCCHHHHHEEEHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCH
KTIMLLQWAMLNRDSLSK
HHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA