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The map label for this gene is slyA [H]

Identifier: 150395959

GI number: 150395959

Start: 789989

End: 790441

Strand: Direct

Name: slyA [H]

Synonym: Smed_0735

Alternate gene names: 150395959

Gene position: 789989-790441 (Clockwise)

Preceding gene: 150395957

Following gene: 150395960

Centisome position: 20.89

GC content: 62.03

Gene sequence:

>453_bases
ATGTCTGAGACGAAGGTCAGTCGCGAACTGTTCGACGCGCTTGCGACGGTTAATCGCAAGCTGAGGTCGGTGTTCGACGC
GCGGGTCAAGGAGCGCGGTCTAACGCTGCCCCGTGCGCGGATGCTGTTCGCTCTCGCCAGGAAAGAAGGTCTCAATCAAC
GCGAATTGGCCGAAGAACTCGATATCGAAACGCCGACCATAGTCCGGCTTCTCGACGGCATGGAGAACCAGGGGTTCATC
GAGCGCCGCGTCGAACTTTCCGACCGGCGTGCGAAGCAGATCTACATGACGGTCTCCGGCCGCGCGCTGGCGGAGGAGAT
CCAGAAGCTTGCAAGCGATATCCGCGAGGAGGTTCTGGGCGGGCTGCGGCCGGAGGAGATCGCCGGTGCGCTGAAGGTCG
TCAACACGATCGCAACGAACATCCAGTCGATCGGGCGGAGTGGCGGCCGATGA

Upstream 100 bases:

>100_bases
GCACGTCCGCGTCCCCGTGCGCGCATCTTGAAACAGGCCCGCCGCCGGATTAAATAGTGCCAAGATGGTTAGCATGCTAG
TAATATGGAAACGATATTAA

Downstream 100 bases:

>100_bases
CATCCAATGCGGCCCCGCAGCCGAGCCTTCCTGCTCAGATGGCGCCCGGTAAATCGGCCCTTTACATTGCCGGCTCCGCG
TTCCTTTTCCTGACGCAGGG

Product: MarR family transcriptional regulator

Products: NA

Alternate protein names: Regulator of antibiotic and pigment protein [H]

Number of amino acids: Translated: 150; Mature: 149

Protein sequence:

>150_residues
MSETKVSRELFDALATVNRKLRSVFDARVKERGLTLPRARMLFALARKEGLNQRELAEELDIETPTIVRLLDGMENQGFI
ERRVELSDRRAKQIYMTVSGRALAEEIQKLASDIREEVLGGLRPEEIAGALKVVNTIATNIQSIGRSGGR

Sequences:

>Translated_150_residues
MSETKVSRELFDALATVNRKLRSVFDARVKERGLTLPRARMLFALARKEGLNQRELAEELDIETPTIVRLLDGMENQGFI
ERRVELSDRRAKQIYMTVSGRALAEEIQKLASDIREEVLGGLRPEEIAGALKVVNTIATNIQSIGRSGGR
>Mature_149_residues
SETKVSRELFDALATVNRKLRSVFDARVKERGLTLPRARMLFALARKEGLNQRELAEELDIETPTIVRLLDGMENQGFIE
RRVELSDRRAKQIYMTVSGRALAEEIQKLASDIREEVLGGLRPEEIAGALKVVNTIATNIQSIGRSGGR

Specific function: Transcription regulator that either activates or represses expression of target genes. Participates in transcriptional activation of pig (prodigiosin pigment) and car (carbapenem antibiotic) gene clusters [H]

COG id: COG1846

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH marR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081950, Length=129, Percent_Identity=32.5581395348837, Blast_Score=65, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000835
- InterPro:   IPR023071
- InterPro:   IPR023187
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01047 MarR [H]

EC number: NA

Molecular weight: Translated: 16836; Mature: 16705

Theoretical pI: Translated: 10.19; Mature: 10.19

Prosite motif: PS01117 HTH_MARR_1 ; PS50995 HTH_MARR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSETKVSRELFDALATVNRKLRSVFDARVKERGLTLPRARMLFALARKEGLNQRELAEEL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHH
DIETPTIVRLLDGMENQGFIERRVELSDRRAKQIYMTVSGRALAEEIQKLASDIREEVLG
CCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHC
GLRPEEIAGALKVVNTIATNIQSIGRSGGR
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SETKVSRELFDALATVNRKLRSVFDARVKERGLTLPRARMLFALARKEGLNQRELAEEL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHH
DIETPTIVRLLDGMENQGFIERRVELSDRRAKQIYMTVSGRALAEEIQKLASDIREEVLG
CCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHC
GLRPEEIAGALKVVNTIATNIQSIGRSGGR
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9402023; 12519208 [H]