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The map label for this gene is acpS [H]

Identifier: 150395904

GI number: 150395904

Start: 732250

End: 732669

Strand: Direct

Name: acpS [H]

Synonym: Smed_0680

Alternate gene names: 150395904

Gene position: 732250-732669 (Clockwise)

Preceding gene: 150395903

Following gene: 150395905

Centisome position: 19.36

GC content: 62.38

Gene sequence:

>420_bases
ATGATCATCGGCATAGGCAGCGATCTCATCGATATCAGACGCATCGAAAATTCGCTCCAGCGCTTCGGCGAGCGTTTCGT
AAACCGGTGTTTCACCGACATCGAGATCGCCAAATCCGACGGCCGCAAGAACCGCGCGGCGTCCTATGCCAAGCGCTTCG
CCGCCAAGGAGGCCTGCTCCAAGGCACTCGGCACCGGCTTAGCGCAGGGCGTATTCTGGAAAGAAATGGGGGTCGTCAAC
CTGCCCGGCGGGAAGCCGACGATGCAACTGACCGGCGGCGCGGCAGCGCGCCTTCGGGAAATGTTGCCGGTCGGACACCG
CGCCGCGATCCATCTGACGATCACCGACGACTTCCCGCTTGCGCAAGCTTTCGTGATTATCGAGGCGCTGCCGGTTGCCC
CCGCCGAGGGAACGGTTTAG

Upstream 100 bases:

>100_bases
CGGCGGGTGGCCTGATATTCTACCCGCTTGCCTTTCAGACGGCGCGTCTCTTTCAGGAGCGCCGCCGGCGGGCCCGCGCG
CACAGACTTGGACATCCAAC

Downstream 100 bases:

>100_bases
AGCACTTGCCGAAAGACCGGCCCGCGGTCGCTTGAAGCTCGGATTTCCCGCGACATATAGCATCGAGTTGCGGGGAGACG
TGCGGCATGAGTTCGGGCGC

Product: 4'-phosphopantetheinyl transferase

Products: NA

Alternate protein names: Holo-ACP synthase; 4'-phosphopantetheinyl transferase AcpS [H]

Number of amino acids: Translated: 139; Mature: 139

Protein sequence:

>139_residues
MIIGIGSDLIDIRRIENSLQRFGERFVNRCFTDIEIAKSDGRKNRAASYAKRFAAKEACSKALGTGLAQGVFWKEMGVVN
LPGGKPTMQLTGGAAARLREMLPVGHRAAIHLTITDDFPLAQAFVIIEALPVAPAEGTV

Sequences:

>Translated_139_residues
MIIGIGSDLIDIRRIENSLQRFGERFVNRCFTDIEIAKSDGRKNRAASYAKRFAAKEACSKALGTGLAQGVFWKEMGVVN
LPGGKPTMQLTGGAAARLREMLPVGHRAAIHLTITDDFPLAQAFVIIEALPVAPAEGTV
>Mature_139_residues
MIIGIGSDLIDIRRIENSLQRFGERFVNRCFTDIEIAKSDGRKNRAASYAKRFAAKEACSKALGTGLAQGVFWKEMGVVN
LPGGKPTMQLTGGAAARLREMLPVGHRAAIHLTITDDFPLAQAFVIIEALPVAPAEGTV

Specific function: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein [H]

COG id: COG0736

COG function: function code I; Phosphopantetheinyl transferase (holo-ACP synthase)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the P-Pant transferase superfamily. AcpS family [H]

Homologues:

Organism=Escherichia coli, GI1788916, Length=128, Percent_Identity=39.84375, Blast_Score=80, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008278
- InterPro:   IPR002582
- InterPro:   IPR004568
- ProDom:   PD004282 [H]

Pfam domain/function: PF01648 ACPS [H]

EC number: =2.7.8.7 [H]

Molecular weight: Translated: 14982; Mature: 14982

Theoretical pI: Translated: 9.87; Mature: 9.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIGIGSDLIDIRRIENSLQRFGERFVNRCFTDIEIAKSDGRKNRAASYAKRFAAKEACS
CEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHH
KALGTGLAQGVFWKEMGVVNLPGGKPTMQLTGGAAARLREMLPVGHRAAIHLTITDDFPL
HHHHHHHHHHHHHHHCCEEECCCCCCEEEECCCHHHHHHHHCCCCCCEEEEEEEECCCCH
AQAFVIIEALPVAPAEGTV
HHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MIIGIGSDLIDIRRIENSLQRFGERFVNRCFTDIEIAKSDGRKNRAASYAKRFAAKEACS
CEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHH
KALGTGLAQGVFWKEMGVVNLPGGKPTMQLTGGAAARLREMLPVGHRAAIHLTITDDFPL
HHHHHHHHHHHHHHHCCEEECCCCCCEEEECCCHHHHHHHHCCCCCCEEEEEEEECCCCH
AQAFVIIEALPVAPAEGTV
HHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]