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The map label for this gene is yfcG [H]

Identifier: 150395886

GI number: 150395886

Start: 713791

End: 714492

Strand: Direct

Name: yfcG [H]

Synonym: Smed_0662

Alternate gene names: 150395886

Gene position: 713791-714492 (Clockwise)

Preceding gene: 150395881

Following gene: 150395888

Centisome position: 18.87

GC content: 59.4

Gene sequence:

>702_bases
ATGACCGCTCCGATCGAGCTCTATTATTGGCCCACGCCGAACGGCTGGAAGATCACCATAATGCTGGAGGAGCTCGGCGT
TCCCTACGTCGTCAAATACATCAATATCGGCCGGGGAGATCAGTTCCAACCAGACTTCCTGAAGATCTCGCCCAACAACC
GGATGCCGGCGATCGTCGACCCGGACGGCCCGGGGGGCGAGCCCATCTCCGTATTCGAATCAGGTGCAATCCTGCAGTAT
CTGGGCCGCAAATACGGCAAGTTCTATCCGACTGACGAGCGCGCCCGTGTCGACGTGGAGCAATGGCTGTTCTGGCAGGT
GGGAGGGCTCGGCCCGATGGCCGGACAAGCGCATCATTTCCGCCAATATGCCCCGGAAAGGATCGCCTACGGCATAGACC
GCTATACCAATGAAGTGAACCGCCTCTACGGCGTGATGAACAAGAGACTTGCCGACCGGCCGTTCCTCGCAGGCGATTAC
TCGATCGCCGACATGGCCGCAGTCGGCTGGGCGATCCCGCATGAAAACCAGGGACAGGACCTGAACGAGTTTCCTAATCT
GAAGCGCTGGTACGACGCCATGCTTGGGCGTCCAGCGGTGAAGAAGGCAATCGAAGTCGGCAAGGAGGAACGGGCTCGCC
AGAAAAGCCTTGCCGAGGATCAAGAGGCACAAAAGGTCCTGTTCGGACAACGCGCCCGCTGA

Upstream 100 bases:

>100_bases
AGTAAAGGCATGCACATAAACATGTCCATGGGGTTGGCGGACTTGCCGTGGAGCGGCCGTGTTCCTAAGTCAGGCTTTCC
GACAACCAGGAGAGAACGCG

Downstream 100 bases:

>100_bases
GGCGTGCGCCGCCGCCTGCATCGCGCTCCCATCGGCTCGACTCAGTCACTTTCACGATTTCAGGTCGATGCGACCTGAAA
TCATTGCGGTCTAAAGGCGT

Product: glutathione S-transferase domain-containing protein

Products: HX; R-S-glutathione

Alternate protein names: GST-like protein yfcG [H]

Number of amino acids: Translated: 233; Mature: 232

Protein sequence:

>233_residues
MTAPIELYYWPTPNGWKITIMLEELGVPYVVKYINIGRGDQFQPDFLKISPNNRMPAIVDPDGPGGEPISVFESGAILQY
LGRKYGKFYPTDERARVDVEQWLFWQVGGLGPMAGQAHHFRQYAPERIAYGIDRYTNEVNRLYGVMNKRLADRPFLAGDY
SIADMAAVGWAIPHENQGQDLNEFPNLKRWYDAMLGRPAVKKAIEVGKEERARQKSLAEDQEAQKVLFGQRAR

Sequences:

>Translated_233_residues
MTAPIELYYWPTPNGWKITIMLEELGVPYVVKYINIGRGDQFQPDFLKISPNNRMPAIVDPDGPGGEPISVFESGAILQY
LGRKYGKFYPTDERARVDVEQWLFWQVGGLGPMAGQAHHFRQYAPERIAYGIDRYTNEVNRLYGVMNKRLADRPFLAGDY
SIADMAAVGWAIPHENQGQDLNEFPNLKRWYDAMLGRPAVKKAIEVGKEERARQKSLAEDQEAQKVLFGQRAR
>Mature_232_residues
TAPIELYYWPTPNGWKITIMLEELGVPYVVKYINIGRGDQFQPDFLKISPNNRMPAIVDPDGPGGEPISVFESGAILQYL
GRKYGKFYPTDERARVDVEQWLFWQVGGLGPMAGQAHHFRQYAPERIAYGIDRYTNEVNRLYGVMNKRLADRPFLAGDYS
IADMAAVGWAIPHENQGQDLNEFPNLKRWYDAMLGRPAVKKAIEVGKEERARQKSLAEDQEAQKVLFGQRAR

Specific function: Has disulfide bond reductase activity (in vitro). Has low hydroperoxidase activity with cumene hydroperoxide. Has very low glutathione-S-transferase activity (in vitro) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GST N-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1788640, Length=202, Percent_Identity=51.980198019802, Blast_Score=209, Evalue=1e-55,
Organism=Escherichia coli, GI87082195, Length=235, Percent_Identity=39.5744680851064, Blast_Score=155, Evalue=2e-39,
Organism=Escherichia coli, GI87081789, Length=177, Percent_Identity=27.683615819209, Blast_Score=70, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6324100, Length=245, Percent_Identity=33.8775510204082, Blast_Score=132, Evalue=6e-32,
Organism=Drosophila melanogaster, GI17933730, Length=227, Percent_Identity=29.5154185022026, Blast_Score=88, Evalue=4e-18,
Organism=Drosophila melanogaster, GI28571670, Length=172, Percent_Identity=30.2325581395349, Blast_Score=88, Evalue=4e-18,
Organism=Drosophila melanogaster, GI45549270, Length=194, Percent_Identity=30.4123711340206, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI17864592, Length=195, Percent_Identity=29.2307692307692, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI17864598, Length=194, Percent_Identity=31.4432989690722, Blast_Score=85, Evalue=3e-17,
Organism=Drosophila melanogaster, GI221378983, Length=196, Percent_Identity=28.5714285714286, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24646259, Length=197, Percent_Identity=29.4416243654822, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI17864594, Length=196, Percent_Identity=28.0612244897959, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI85725204, Length=198, Percent_Identity=26.7676767676768, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI17737923, Length=198, Percent_Identity=26.7676767676768, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI17864596, Length=188, Percent_Identity=27.6595744680851, Blast_Score=71, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24646249, Length=199, Percent_Identity=29.1457286432161, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24646251, Length=179, Percent_Identity=26.2569832402235, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010987
- InterPro:   IPR004045
- InterPro:   IPR017933
- InterPro:   IPR004046
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00043 GST_C; PF02798 GST_N [H]

EC number: 2.5.1.18

Molecular weight: Translated: 26596; Mature: 26464

Theoretical pI: Translated: 7.71; Mature: 7.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAPIELYYWPTPNGWKITIMLEELGVPYVVKYINIGRGDQFQPDFLKISPNNRMPAIVD
CCCCEEEEEECCCCCEEEEEEHHHCCCCEEEEEEECCCCCCCCCCEEEECCCCCCCEEEC
PDGPGGEPISVFESGAILQYLGRKYGKFYPTDERARVDVEQWLFWQVGGLGPMAGQAHHF
CCCCCCCCHHHHHCCHHHHHHHHHHCCCCCCCCCHHCCHHHHHHHHCCCCCCCCCCHHHH
RQYAPERIAYGIDRYTNEVNRLYGVMNKRLADRPFLAGDYSIADMAAVGWAIPHENQGQD
HHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCCCCCC
LNEFPNLKRWYDAMLGRPAVKKAIEVGKEERARQKSLAEDQEAQKVLFGQRAR
HHHCCCHHHHHHHHHCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TAPIELYYWPTPNGWKITIMLEELGVPYVVKYINIGRGDQFQPDFLKISPNNRMPAIVD
CCCEEEEEECCCCCEEEEEEHHHCCCCEEEEEEECCCCCCCCCCEEEECCCCCCCEEEC
PDGPGGEPISVFESGAILQYLGRKYGKFYPTDERARVDVEQWLFWQVGGLGPMAGQAHHF
CCCCCCCCHHHHHCCHHHHHHHHHHCCCCCCCCCHHCCHHHHHHHHCCCCCCCCCCHHHH
RQYAPERIAYGIDRYTNEVNRLYGVMNKRLADRPFLAGDYSIADMAAVGWAIPHENQGQD
HHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCCCCCC
LNEFPNLKRWYDAMLGRPAVKKAIEVGKEERARQKSLAEDQEAQKVLFGQRAR
HHHCCCHHHHHHHHHCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: RX; glutathione

Specific reaction: RX + glutathione = HX + R-S-glutathione

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]