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The map label for this gene is blaP [H]

Identifier: 150395818

GI number: 150395818

Start: 641373

End: 642263

Strand: Direct

Name: blaP [H]

Synonym: Smed_0594

Alternate gene names: 150395818

Gene position: 641373-642263 (Clockwise)

Preceding gene: 150395815

Following gene: 150395825

Centisome position: 16.96

GC content: 63.64

Gene sequence:

>891_bases
ATGCCTTTGCACATAACCCGCCGAGAAATGCTGGCCGCCTCGGCCATGCTCTATCCGGCGCTCGCCCTGGGAACGCCGGC
ACATGCGGCCACTGCGGCGGACGATGACGTTACGGAACGGCTTCGTCAGCTTGAAGAGCGTACCGGCGGACGTTTGGGCG
TCGCTGTGCTCGATATGGAAACGAATATCTCGTTCGGATACCGGGAGACCGAGCGTTTCGCAATGTGTTCTACCTTCAAG
GCGCTCGCGGCGGCTTGTGCGCTCGCCCGCGTGGATCGGGGGGAGGAAAAACTCGACCGGCGGATCACGTTCGGCAAGGA
GGTCTTGCTGCCTCATTCGCCGGTAACCGAAAAGCACGTCGGCGGAAACGGCATGACCATCGCGGAACTTTGCGAAGCGG
CGATCACCATCAGCGACAATGCCGCTGGCAACCTGCTGCTCGAAAGTTTCGGAGGTCCACAGGGGCTGACGTCGTGGCTA
CGCTCGATTGGCGACAATACCACGCGCCTCGACCGAACGGAGCCCGACCTGAACGAAGCCCGCAAGGGCGATCCGCGCGA
CACCACCACACCGGCCGCCATGCTGGACACGCTTGGAAAACTGGCTCTCGGCTCGGTCCTGTCCGAAAACGGGCGCGGAC
AGCTCGTCGACTGGTTGGTTGCCAACGAAACCGGTGACGCGCGCCTTCGCGCGGGGCTGCCCAAGGATTGGCGCATCGGC
GACAAGACAGGGACCAGCTCCACCGGCGCAGTCTCCGACATAGCGCTCGCCTGGCCGCCCGGCCGCGGCCCACTCCTGGT
TGCCGTCTATACCGGTGAAGCGAAAGCGCCGGTCAGCGACCTGAATCCGGTCTTTGCGGAAATAGGCAAGATCGCCGCCG
AGATCGTTTGA

Upstream 100 bases:

>100_bases
CGCCGTCTAGCGATTCGACCGTCGGAGTCGACAGGAATAACATTCAATATCAATAATTTAGCTATGTCTTGGCGCTTGAG
CCGCACAGACGGAGGAACAC

Downstream 100 bases:

>100_bases
CCATGCTCTCGCGAACGGAGCGCGCTCTGGCGAGCGCGCCCGTCGATTCGAACCTGTGCGTCAGGGCAGCGTATAGGCGA
TGACGTAATCGCCCGGCTTG

Product: beta-lactamase

Products: NA

Alternate protein names: Carbenicillinase [H]

Number of amino acids: Translated: 296; Mature: 295

Protein sequence:

>296_residues
MPLHITRREMLAASAMLYPALALGTPAHAATAADDDVTERLRQLEERTGGRLGVAVLDMETNISFGYRETERFAMCSTFK
ALAAACALARVDRGEEKLDRRITFGKEVLLPHSPVTEKHVGGNGMTIAELCEAAITISDNAAGNLLLESFGGPQGLTSWL
RSIGDNTTRLDRTEPDLNEARKGDPRDTTTPAAMLDTLGKLALGSVLSENGRGQLVDWLVANETGDARLRAGLPKDWRIG
DKTGTSSTGAVSDIALAWPPGRGPLLVAVYTGEAKAPVSDLNPVFAEIGKIAAEIV

Sequences:

>Translated_296_residues
MPLHITRREMLAASAMLYPALALGTPAHAATAADDDVTERLRQLEERTGGRLGVAVLDMETNISFGYRETERFAMCSTFK
ALAAACALARVDRGEEKLDRRITFGKEVLLPHSPVTEKHVGGNGMTIAELCEAAITISDNAAGNLLLESFGGPQGLTSWL
RSIGDNTTRLDRTEPDLNEARKGDPRDTTTPAAMLDTLGKLALGSVLSENGRGQLVDWLVANETGDARLRAGLPKDWRIG
DKTGTSSTGAVSDIALAWPPGRGPLLVAVYTGEAKAPVSDLNPVFAEIGKIAAEIV
>Mature_295_residues
PLHITRREMLAASAMLYPALALGTPAHAATAADDDVTERLRQLEERTGGRLGVAVLDMETNISFGYRETERFAMCSTFKA
LAAACALARVDRGEEKLDRRITFGKEVLLPHSPVTEKHVGGNGMTIAELCEAAITISDNAAGNLLLESFGGPQGLTSWLR
SIGDNTTRLDRTEPDLNEARKGDPRDTTTPAAMLDTLGKLALGSVLSENGRGQLVDWLVANETGDARLRAGLPKDWRIGD
KTGTSSTGAVSDIALAWPPGRGPLLVAVYTGEAKAPVSDLNPVFAEIGKIAAEIV

Specific function: Hydrolyzes carbenicillin [H]

COG id: COG2367

COG function: function code V; Beta-lactamase class A

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-A beta-lactamase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001466
- InterPro:   IPR000871 [H]

Pfam domain/function: PF00144 Beta-lactamase [H]

EC number: =3.5.2.6 [H]

Molecular weight: Translated: 31474; Mature: 31343

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: PS00572 GLYCOSYL_HYDROL_F1_1 ; PS00146 BETA_LACTAMASE_A

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLHITRREMLAASAMLYPALALGTPAHAATAADDDVTERLRQLEERTGGRLGVAVLDME
CCCCCCHHHHHHHHHHHHHHHHCCCCCHHCCCCCHHHHHHHHHHHHHCCCEEEEEEEEEE
TNISFGYRETERFAMCSTFKALAAACALARVDRGEEKLDRRITFGKEVLLPHSPVTEKHV
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCEEECCCCCCCHHCC
GGNGMTIAELCEAAITISDNAAGNLLLESFGGPQGLTSWLRSIGDNTTRLDRTEPDLNEA
CCCCCCHHHHHHHHEEECCCCCCCHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHH
RKGDPRDTTTPAAMLDTLGKLALGSVLSENGRGQLVDWLVANETGDARLRAGLPKDWRIG
CCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCEECCCCCCCCCC
DKTGTSSTGAVSDIALAWPPGRGPLLVAVYTGEAKAPVSDLNPVFAEIGKIAAEIV
CCCCCCCCCCHHHEEEECCCCCCCEEEEEEECCCCCCHHHCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
PLHITRREMLAASAMLYPALALGTPAHAATAADDDVTERLRQLEERTGGRLGVAVLDME
CCCCCHHHHHHHHHHHHHHHHCCCCCHHCCCCCHHHHHHHHHHHHHCCCEEEEEEEEEE
TNISFGYRETERFAMCSTFKALAAACALARVDRGEEKLDRRITFGKEVLLPHSPVTEKHV
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCEEECCCCCCCHHCC
GGNGMTIAELCEAAITISDNAAGNLLLESFGGPQGLTSWLRSIGDNTTRLDRTEPDLNEA
CCCCCCHHHHHHHHEEECCCCCCCHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHH
RKGDPRDTTTPAAMLDTLGKLALGSVLSENGRGQLVDWLVANETGDARLRAGLPKDWRIG
CCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCEECCCCCCCCCC
DKTGTSSTGAVSDIALAWPPGRGPLLVAVYTGEAKAPVSDLNPVFAEIGKIAAEIV
CCCCCCCCCCHHHEEEECCCCCCCEEEEEEECCCCCCHHHCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1840585 [H]