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The map label for this gene is mtlD

Identifier: 150394669

GI number: 150394669

Start: 2316330

End: 2317436

Strand: Direct

Name: mtlD

Synonym: SaurJH1_2229

Alternate gene names: 150394669

Gene position: 2316330-2317436 (Clockwise)

Preceding gene: 150394668

Following gene: 150394682

Centisome position: 79.69

GC content: 33.33

Gene sequence:

>1107_bases
ATGAAAGCAGTTCACTTTGGTGCTGGTAACATAGGTCGTGGTTTCATTGGTTATATTCTTGCAGACAACAATGTTAAAGT
AACATTTGCAGACGTCAATGAAGAAATCATTAATGCTTTAGCTCATGATCATCAATACGATGTTATTTTAGCTGATGAGT
CTAAAACAACGACGCGCGTGAATAATGTTGATGCAATTAATTCAATGCAACCTTCTGAAGCGTTGAAACAAGCAATTCTA
GAAGCTGATATTATTACAACAGCTGTTGGTGTTAACATACTACCTATTATTGCTAAATCTTTTGCGCCTTTCTTAAAAGA
AAAAACAAACCATGTTAATATTGTTGCTTGTGAGAATGCTATTATGGCAACTGATACATTGAAAAAAGCAGTACTTGATA
TTACTGGCCCTCTTGGTAACAATATTCATTTTGCTAACTCAGCAGTTGATAGAATTGTACCATTACAAAAGAATGAAAAT
ATATTAGACGTTATGGTTGAGCCATTTTACGAATGGGTTGTTGAAAAAGATGCATGGTATGGTCCAGAACTAAACCATAT
TAAATATGTTGATGATTTAACACCATATATTGAGCGTAAATTATTAACTGTGAATACAGGACATGCATATTTAGCGTATG
CTGGTAAATTTGCAGGTAAAGCTACCGTATTAGACGCTGTAAAAGATAGTTCAATTGAAGCTGGCTTACGCCGTGTTTTA
GCTGAAACAAGTCAATATATTACTAATGAATTTGATTTTACTGAAGCGGAACAAGCTGGTTATGTTGAAAAAATAATAGA
CCGTTTCAACAATTCTTATTTATCTGATGAAGTGACACGTGTCGGACGAGGTACGTTACGTAAAATTGGCCCTAAAGATA
GAATTATAAAACCATTAACATATCTTTATAATAAAGATTTAGAACGCACTGGTTTATTAAATACAGCTGCATTGTTATTG
AAGTATGATGATACAGCAGACCAAGAAACTGTTGAGAAAAATAATTACATTAAAGAACACGGTTTAAAAGCGTTTTTAAG
CGAATATGCTAAAGTTGACGATGGCTTAGCCGATGAAATAATTGAAGCGTACAATTCACTTTCATAA

Upstream 100 bases:

>100_bases
AAATTGCAATTACATTTAGCGAAGAAGAAAATGTGGATCGTATCGTTCAAGCAAAATCTGCAGAAGAAATTAAACAAGTA
TTCGAGGAGGCAGATGCATA

Downstream 100 bases:

>100_bases
TTTATTGAGCTTTGTTTGAAACAAGAAGTTTCCAACGTTATTCGTTAACAATCAGTAATAATGTAGTAGTTCCGTTGAAT
TAACAATATTAAATTTCTGA

Product: mannitol-1-phosphate 5-dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 368; Mature: 368

Protein sequence:

>368_residues
MKAVHFGAGNIGRGFIGYILADNNVKVTFADVNEEIINALAHDHQYDVILADESKTTTRVNNVDAINSMQPSEALKQAIL
EADIITTAVGVNILPIIAKSFAPFLKEKTNHVNIVACENAIMATDTLKKAVLDITGPLGNNIHFANSAVDRIVPLQKNEN
ILDVMVEPFYEWVVEKDAWYGPELNHIKYVDDLTPYIERKLLTVNTGHAYLAYAGKFAGKATVLDAVKDSSIEAGLRRVL
AETSQYITNEFDFTEAEQAGYVEKIIDRFNNSYLSDEVTRVGRGTLRKIGPKDRIIKPLTYLYNKDLERTGLLNTAALLL
KYDDTADQETVEKNNYIKEHGLKAFLSEYAKVDDGLADEIIEAYNSLS

Sequences:

>Translated_368_residues
MKAVHFGAGNIGRGFIGYILADNNVKVTFADVNEEIINALAHDHQYDVILADESKTTTRVNNVDAINSMQPSEALKQAIL
EADIITTAVGVNILPIIAKSFAPFLKEKTNHVNIVACENAIMATDTLKKAVLDITGPLGNNIHFANSAVDRIVPLQKNEN
ILDVMVEPFYEWVVEKDAWYGPELNHIKYVDDLTPYIERKLLTVNTGHAYLAYAGKFAGKATVLDAVKDSSIEAGLRRVL
AETSQYITNEFDFTEAEQAGYVEKIIDRFNNSYLSDEVTRVGRGTLRKIGPKDRIIKPLTYLYNKDLERTGLLNTAALLL
KYDDTADQETVEKNNYIKEHGLKAFLSEYAKVDDGLADEIIEAYNSLS
>Mature_368_residues
MKAVHFGAGNIGRGFIGYILADNNVKVTFADVNEEIINALAHDHQYDVILADESKTTTRVNNVDAINSMQPSEALKQAIL
EADIITTAVGVNILPIIAKSFAPFLKEKTNHVNIVACENAIMATDTLKKAVLDITGPLGNNIHFANSAVDRIVPLQKNEN
ILDVMVEPFYEWVVEKDAWYGPELNHIKYVDDLTPYIERKLLTVNTGHAYLAYAGKFAGKATVLDAVKDSSIEAGLRRVL
AETSQYITNEFDFTEAEQAGYVEKIIDRFNNSYLSDEVTRVGRGTLRKIGPKDRIIKPLTYLYNKDLERTGLLNTAALLL
KYDDTADQETVEKNNYIKEHGLKAFLSEYAKVDDGLADEIIEAYNSLS

Specific function: Unknown

COG id: COG0246

COG function: function code G; Mannitol-1-phosphate/altronate dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mannitol dehydrogenase family

Homologues:

Organism=Escherichia coli, GI1790028, Length=388, Percent_Identity=36.5979381443299, Blast_Score=242, Evalue=2e-65,
Organism=Escherichia coli, GI1788497, Length=206, Percent_Identity=26.6990291262136, Blast_Score=78, Evalue=9e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MTLD_STAA1 (A7X522)

Other databases:

- EMBL:   AP009324
- RefSeq:   YP_001442733.1
- ProteinModelPortal:   A7X522
- STRING:   A7X522
- EnsemblBacteria:   EBSTAT00000002807
- GeneID:   5560450
- GenomeReviews:   AP009324_GR
- KEGG:   saw:SAHV_2143
- eggNOG:   COG0246
- GeneTree:   EBGT00050000024485
- HOGENOM:   HBG568825
- OMA:   FTVNTGH
- ProtClustDB:   PRK02318
- BioCyc:   SAUR418127:SAHV_2143-MONOMER
- HAMAP:   MF_00196
- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR023028
- InterPro:   IPR000669
- InterPro:   IPR013118
- InterPro:   IPR023027
- InterPro:   IPR013131
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- Gene3D:   G3DSA:1.10.1040.10
- PRINTS:   PR00084

Pfam domain/function: PF01232 Mannitol_dh; PF08125 Mannitol_dh_C; SSF48179 6DGDH_C_like

EC number: =1.1.1.17

Molecular weight: Translated: 40937; Mature: 40937

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: PS00974 MANNITOL_DHGENASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAVHFGAGNIGRGFIGYILADNNVKVTFADVNEEIINALAHDHQYDVILADESKTTTRV
CCEEEECCCCCCCCEEEEEEECCCEEEEEECCCHHHHHHHHCCCCEEEEEECCCCCCEEC
NNVDAINSMQPSEALKQAILEADIITTAVGVNILPIIAKSFAPFLKEKTNHVNIVACENA
CCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCC
IMATDTLKKAVLDITGPLGNNIHFANSAVDRIVPLQKNENILDVMVEPFYEWVVEKDAWY
HHHHHHHHHHHHHHCCCCCCCEEECCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCC
GPELNHIKYVDDLTPYIERKLLTVNTGHAYLAYAGKFAGKATVLDAVKDSSIEAGLRRVL
CCCCCCEEEHHHHHHHHCCEEEEEECCCEEEEEHHHCCCCHHHHHHHHCCHHHHHHHHHH
AETSQYITNEFDFTEAEQAGYVEKIIDRFNNSYLSDEVTRVGRGTLRKIGPKDRIIKPLT
HHHHHHHHCCCCCCCHHHCCHHHHHHHHHCCCHHHHHHHHHCCHHHHHCCCHHHHHHHHH
YLYNKDLERTGLLNTAALLLKYDDTADQETVEKNNYIKEHGLKAFLSEYAKVDDGLADEI
HHHCCCCHHHCCHHHEEEEEEECCCCCHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHH
IEAYNSLS
HHHHHCCC
>Mature Secondary Structure
MKAVHFGAGNIGRGFIGYILADNNVKVTFADVNEEIINALAHDHQYDVILADESKTTTRV
CCEEEECCCCCCCCEEEEEEECCCEEEEEECCCHHHHHHHHCCCCEEEEEECCCCCCEEC
NNVDAINSMQPSEALKQAILEADIITTAVGVNILPIIAKSFAPFLKEKTNHVNIVACENA
CCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCC
IMATDTLKKAVLDITGPLGNNIHFANSAVDRIVPLQKNENILDVMVEPFYEWVVEKDAWY
HHHHHHHHHHHHHHCCCCCCCEEECCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCC
GPELNHIKYVDDLTPYIERKLLTVNTGHAYLAYAGKFAGKATVLDAVKDSSIEAGLRRVL
CCCCCCEEEHHHHHHHHCCEEEEEECCCEEEEEHHHCCCCHHHHHHHHCCHHHHHHHHHH
AETSQYITNEFDFTEAEQAGYVEKIIDRFNNSYLSDEVTRVGRGTLRKIGPKDRIIKPLT
HHHHHHHHCCCCCCCHHHCCHHHHHHHHHCCCHHHHHHHHHCCHHHHHCCCHHHHHHHHH
YLYNKDLERTGLLNTAALLLKYDDTADQETVEKNNYIKEHGLKAFLSEYAKVDDGLADEI
HHHCCCCHHHCCHHHEEEEEEECCCCCHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHH
IEAYNSLS
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA