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The map label for this gene is mtlR [H]

Identifier: 150394667

GI number: 150394667

Start: 2313752

End: 2315884

Strand: Direct

Name: mtlR [H]

Synonym: SaurJH1_2227

Alternate gene names: 150394667

Gene position: 2313752-2315884 (Clockwise)

Preceding gene: 150394666

Following gene: 150394668

Centisome position: 79.61

GC content: 33.38

Gene sequence:

>2133_bases
ATGTTATTGAGTACACGTGAAAAAGAAATGATAGCCCTATTGATTAAGTACCACAGTCAATATATCACTATACACGACAT
TGCTCAGCAACTTGCGGTGTCCTCTCGTACTATTCACCGTGAATTAAAAGGTGTTGAAGCATATTTAACTTCATTTTCAT
TAACTTTAGAACGCGCAAACAAAAAAGGGCTACGCATTGCTGGCGCAGATTCTGATTTAAACGATTTGAAGCAATCGATT
GCACAACATCAAACCATTGACTTATCTGTTGAAGAGCAGAAAGTAATTATTATATACGCTTTGATACAAGCCAAGGAGCC
AGTTAAACAATATAGTTTAGCGCAAGAAATTGGCGTTTCTGTCCAGACTTTAGCAAAGATGTTAGATGATTTAGAGCTTG
ATTTAAATAAGTACCAACTATCTTTATCTCGAAAGCGTGGCGAAGGCATTTACTTGGTAGGTACTGAATCAAAGAAACGT
GAATTTTTAAGTCAATTAATGGTGAATAACTTAAATAGTACTAGCGTTTATTCAGTAATTGAAAATCATTTTGTCTTTCA
TTCATTAAATCAAATCCACAAAGACTTTGTTGACTTAGAGCGCATTTTTAATGTTGAAAGACTATTAATGGACTACCTAA
GTGCCTTACCCTACCAACTTACCGAATCAAGTTATTTAACTTTAACTGTCCATATCGTGCTATCCATTTCACGTATAAAA
AATGGAGAGTATGTCGCATTAAACGATGATATTTATGATTCTGTACAAAACACATTTGAACACAAAGTAGCAAGCGAACT
TGCTGATAAACTTGGTCAAATATATGACGTCACGTTTAATCAGGCAGAAATTGCTTTCATTACTATCCATTTACGTGGAG
CTAAACGAAAAAATCTTAATGATACATCATTAAATAATCGTTGTGAAGAAAACAAAATTAAAGCGTTTGTTAACAAAGTA
GAAATGATTTCCGGTATGACATTTGCAGATTTGGATACTTTAGTAGATGGACTGACGCTACACCTTAATCCTGCAATCAA
TCGTTTGCAAGCTAATATCGAGACCTATAATCCGTTAACAGACATGATTAAGTTCAAATATCCAAGACTATTTGAAAATG
TAAGATTAGCTTTAAATGATTGTTGGCCTGATTTGATTTTTCCAGAGAGTGAAATTGCTTTTATAGTTTTACACTTTGGT
GGCTCGATTAAAAACCAAGGTAATCGATTTTTAAACATATTAGTCGTTTGCAGCAGTGGTATGGGAACTAGTCGTCTATT
ATCAACTCGTCTAGAGCAAGTTTTTAGTGAGATTGAGCGTATTACACAAGCATCAGTCAGCGATTTGAAGTCACTAGATT
TAAGTCAATATGATGGCATTATTTCTACTGTGAATTTAGACATCGACTCCCCCTATTTAACGGTAAACCCATTATTACCA
GATAGTGATATCAGTTATGTCGCACAGTTTTTAAATACAAAGTCTACGTTCCAAGAGACGCATGATAAATCATCAAACAT
GATTGATAAGGATGATGTTCATGTTGAAACGAAAGATGTTGATGGCAACACATCTTTTGAAAATGAACAAACTTCATACT
TAACTTCAGTTTTCGAAAAACATTTAAGTGACGAAAAATCAGAACAATTATTGCATCATATGCGTTCGGGTTTAACTTTG
CTTGATTCAGTGAAAATAGTTAGTACCGAAGTTAAACAGTGGCAAACATATATCGCAGATTATCTATATCAATGCGATGT
AATAAACGATCCAACGTCATTCGCTGAACTACTAGAGCAACGATTGATTGACAATCCAGGATGGATATTAAGTCCATATC
CTGTTGCAATACCACACCTAAGAGACAATATGATTAAACACCCTATGATTCTAATCACAGTTTTAGAAGAACCGTTAACA
TTGCCTAGTATTCAAAATGACAATCAAACAATTAAATATATGATTTCCATGTTTATTCCTGACAATGATTTTATGGCATC
ACTGGTAAGTGACTTGTCCGAATTTTTAAGTTTGAAATTAGAATCTATTGATACTTTTATGGAAAATCCACAGGAACTTG
AAACATTATTAAGAAACAAATTTTTAGAACGAATTAAAAAACAATTTATTTAG

Upstream 100 bases:

>100_bases
AATTTCCTTAATTCACCAAGATATGAAGAACTTTTAAATAATCTAAAAAAAGATGATCAAGCATAATAATTAAATAAATT
AAAAAATGGAGGATACCGCC

Downstream 100 bases:

>100_bases
GAGTGTACAAAATGAGCGAATTATTTAGTAATGACAATATCTTTTTAAATGTAAATGTTAACAGCCAAAATGAAGCAATT
GAAAAAGCAGGTAAAGCCTT

Product: PRD domain-containing protein

Products: NA

Alternate protein names: Mannitol operon transcriptional activator; Mtl operon transcriptional activator; Putative phosphotransferase enzyme IIB component; Putative PTS system EIIB component; Putative phosphotransferase enzyme IIA component; Putative PTS system EIIA component [H]

Number of amino acids: Translated: 710; Mature: 710

Protein sequence:

>710_residues
MLLSTREKEMIALLIKYHSQYITIHDIAQQLAVSSRTIHRELKGVEAYLTSFSLTLERANKKGLRIAGADSDLNDLKQSI
AQHQTIDLSVEEQKVIIIYALIQAKEPVKQYSLAQEIGVSVQTLAKMLDDLELDLNKYQLSLSRKRGEGIYLVGTESKKR
EFLSQLMVNNLNSTSVYSVIENHFVFHSLNQIHKDFVDLERIFNVERLLMDYLSALPYQLTESSYLTLTVHIVLSISRIK
NGEYVALNDDIYDSVQNTFEHKVASELADKLGQIYDVTFNQAEIAFITIHLRGAKRKNLNDTSLNNRCEENKIKAFVNKV
EMISGMTFADLDTLVDGLTLHLNPAINRLQANIETYNPLTDMIKFKYPRLFENVRLALNDCWPDLIFPESEIAFIVLHFG
GSIKNQGNRFLNILVVCSSGMGTSRLLSTRLEQVFSEIERITQASVSDLKSLDLSQYDGIISTVNLDIDSPYLTVNPLLP
DSDISYVAQFLNTKSTFQETHDKSSNMIDKDDVHVETKDVDGNTSFENEQTSYLTSVFEKHLSDEKSEQLLHHMRSGLTL
LDSVKIVSTEVKQWQTYIADYLYQCDVINDPTSFAELLEQRLIDNPGWILSPYPVAIPHLRDNMIKHPMILITVLEEPLT
LPSIQNDNQTIKYMISMFIPDNDFMASLVSDLSEFLSLKLESIDTFMENPQELETLLRNKFLERIKKQFI

Sequences:

>Translated_710_residues
MLLSTREKEMIALLIKYHSQYITIHDIAQQLAVSSRTIHRELKGVEAYLTSFSLTLERANKKGLRIAGADSDLNDLKQSI
AQHQTIDLSVEEQKVIIIYALIQAKEPVKQYSLAQEIGVSVQTLAKMLDDLELDLNKYQLSLSRKRGEGIYLVGTESKKR
EFLSQLMVNNLNSTSVYSVIENHFVFHSLNQIHKDFVDLERIFNVERLLMDYLSALPYQLTESSYLTLTVHIVLSISRIK
NGEYVALNDDIYDSVQNTFEHKVASELADKLGQIYDVTFNQAEIAFITIHLRGAKRKNLNDTSLNNRCEENKIKAFVNKV
EMISGMTFADLDTLVDGLTLHLNPAINRLQANIETYNPLTDMIKFKYPRLFENVRLALNDCWPDLIFPESEIAFIVLHFG
GSIKNQGNRFLNILVVCSSGMGTSRLLSTRLEQVFSEIERITQASVSDLKSLDLSQYDGIISTVNLDIDSPYLTVNPLLP
DSDISYVAQFLNTKSTFQETHDKSSNMIDKDDVHVETKDVDGNTSFENEQTSYLTSVFEKHLSDEKSEQLLHHMRSGLTL
LDSVKIVSTEVKQWQTYIADYLYQCDVINDPTSFAELLEQRLIDNPGWILSPYPVAIPHLRDNMIKHPMILITVLEEPLT
LPSIQNDNQTIKYMISMFIPDNDFMASLVSDLSEFLSLKLESIDTFMENPQELETLLRNKFLERIKKQFI
>Mature_710_residues
MLLSTREKEMIALLIKYHSQYITIHDIAQQLAVSSRTIHRELKGVEAYLTSFSLTLERANKKGLRIAGADSDLNDLKQSI
AQHQTIDLSVEEQKVIIIYALIQAKEPVKQYSLAQEIGVSVQTLAKMLDDLELDLNKYQLSLSRKRGEGIYLVGTESKKR
EFLSQLMVNNLNSTSVYSVIENHFVFHSLNQIHKDFVDLERIFNVERLLMDYLSALPYQLTESSYLTLTVHIVLSISRIK
NGEYVALNDDIYDSVQNTFEHKVASELADKLGQIYDVTFNQAEIAFITIHLRGAKRKNLNDTSLNNRCEENKIKAFVNKV
EMISGMTFADLDTLVDGLTLHLNPAINRLQANIETYNPLTDMIKFKYPRLFENVRLALNDCWPDLIFPESEIAFIVLHFG
GSIKNQGNRFLNILVVCSSGMGTSRLLSTRLEQVFSEIERITQASVSDLKSLDLSQYDGIISTVNLDIDSPYLTVNPLLP
DSDISYVAQFLNTKSTFQETHDKSSNMIDKDDVHVETKDVDGNTSFENEQTSYLTSVFEKHLSDEKSEQLLHHMRSGLTL
LDSVKIVSTEVKQWQTYIADYLYQCDVINDPTSFAELLEQRLIDNPGWILSPYPVAIPHLRDNMIKHPMILITVLEEPLT
LPSIQNDNQTIKYMISMFIPDNDFMASLVSDLSEFLSLKLESIDTFMENPQELETLLRNKFLERIKKQFI

Specific function: Positively regulates the expression of the mtlAFD operon involved in the uptake and catabolism of mannitol [H]

COG id: COG3711

COG function: function code K; Transcriptional antiterminator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIB type-2 domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013196
- InterPro:   IPR007737
- InterPro:   IPR011608
- InterPro:   IPR016152
- InterPro:   IPR002178
- InterPro:   IPR013011
- InterPro:   IPR003501
- InterPro:   IPR011991 [H]

Pfam domain/function: PF08279 HTH_11; PF05043 Mga; PF00874 PRD; PF02302 PTS_IIB [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 81157; Mature: 81157

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: PS51094 PTS_EIIA_TYPE_2 ; PS51099 PTS_EIIB_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLSTREKEMIALLIKYHSQYITIHDIAQQLAVSSRTIHRELKGVEAYLTSFSLTLERAN
CCCCCCHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
KKGLRIAGADSDLNDLKQSIAQHQTIDLSVEEQKVIIIYALIQAKEPVKQYSLAQEIGVS
CCCCEEECCCCCHHHHHHHHHHCCEEEEEECCCEEEEEEEEHHCCCHHHHHHHHHHHCCC
VQTLAKMLDDLELDLNKYQLSLSRKRGEGIYLVGTESKKREFLSQLMVNNLNSTSVYSVI
HHHHHHHHHHHHCCHHHHHEEEHHCCCCEEEEEECCHHHHHHHHHHHHCCCCCHHHHHHH
ENHFVFHSLNQIHKDFVDLERIFNVERLLMDYLSALPYQLTESSYLTLTVHIVLSISRIK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCEEEEEHEEHHHHHHCC
NGEYVALNDDIYDSVQNTFEHKVASELADKLGQIYDVTFNQAEIAFITIHLRGAKRKNLN
CCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCEEEEEEEEEECCCCCCCC
DTSLNNRCEENKIKAFVNKVEMISGMTFADLDTLVDGLTLHLNPAINRLQANIETYNPLT
CCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCEEEEECHHHHHHHHCCHHCCCHH
DMIKFKYPRLFENVRLALNDCWPDLIFPESEIAFIVLHFGGSIKNQGNRFLNILVVCSSG
HHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCCCCCCCCCEEEEEEEECCC
MGTSRLLSTRLEQVFSEIERITQASVSDLKSLDLSQYDGIISTVNLDIDSPYLTVNPLLP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCEEEEEEEECCCCEEEECCCCC
DSDISYVAQFLNTKSTFQETHDKSSNMIDKDDVHVETKDVDGNTSFENEQTSYLTSVFEK
CCCHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHH
HLSDEKSEQLLHHMRSGLTLLDSVKIVSTEVKQWQTYIADYLYQCDVINDPTSFAELLEQ
HHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
RLIDNPGWILSPYPVAIPHLRDNMIKHPMILITVLEEPLTLPSIQNDNQTIKYMISMFIP
HHCCCCCEEECCCCCCCCHHHHHHHCCCEEEEEEHHCCCCCCCCCCCCHHHHHHHHHHCC
DNDFMASLVSDLSEFLSLKLESIDTFMENPQELETLLRNKFLERIKKQFI
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLLSTREKEMIALLIKYHSQYITIHDIAQQLAVSSRTIHRELKGVEAYLTSFSLTLERAN
CCCCCCHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
KKGLRIAGADSDLNDLKQSIAQHQTIDLSVEEQKVIIIYALIQAKEPVKQYSLAQEIGVS
CCCCEEECCCCCHHHHHHHHHHCCEEEEEECCCEEEEEEEEHHCCCHHHHHHHHHHHCCC
VQTLAKMLDDLELDLNKYQLSLSRKRGEGIYLVGTESKKREFLSQLMVNNLNSTSVYSVI
HHHHHHHHHHHHCCHHHHHEEEHHCCCCEEEEEECCHHHHHHHHHHHHCCCCCHHHHHHH
ENHFVFHSLNQIHKDFVDLERIFNVERLLMDYLSALPYQLTESSYLTLTVHIVLSISRIK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCEEEEEHEEHHHHHHCC
NGEYVALNDDIYDSVQNTFEHKVASELADKLGQIYDVTFNQAEIAFITIHLRGAKRKNLN
CCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCEEEEEEEEEECCCCCCCC
DTSLNNRCEENKIKAFVNKVEMISGMTFADLDTLVDGLTLHLNPAINRLQANIETYNPLT
CCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCEEEEECHHHHHHHHCCHHCCCHH
DMIKFKYPRLFENVRLALNDCWPDLIFPESEIAFIVLHFGGSIKNQGNRFLNILVVCSSG
HHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCCCCCCCCCEEEEEEEECCC
MGTSRLLSTRLEQVFSEIERITQASVSDLKSLDLSQYDGIISTVNLDIDSPYLTVNPLLP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCEEEEEEEECCCCEEEECCCCC
DSDISYVAQFLNTKSTFQETHDKSSNMIDKDDVHVETKDVDGNTSFENEQTSYLTSVFEK
CCCHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHH
HLSDEKSEQLLHHMRSGLTLLDSVKIVSTEVKQWQTYIADYLYQCDVINDPTSFAELLEQ
HHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
RLIDNPGWILSPYPVAIPHLRDNMIKHPMILITVLEEPLTLPSIQNDNQTIKYMISMFIP
HHCCCCCEEECCCCCCCCHHHHHHHCCCEEEEEEHHCCCCCCCCCCCCHHHHHHHHHHCC
DNDFMASLVSDLSEFLSLKLESIDTFMENPQELETLLRNKFLERIKKQFI
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]