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The map label for this gene is xerC

Identifier: 15004784

GI number: 15004784

Start: 84265

End: 85236

Strand: Direct

Name: xerC

Synonym: CA_P0080

Alternate gene names: 15004784

Gene position: 84265-85236 (Clockwise)

Preceding gene: 15004780

Following gene: 15004785

Centisome position: 43.89

GC content: 29.01

Gene sequence:

>972_bases
ATGCCTATGACCTTAACTGGGTTTCTTATTTACATGACTAATATTAAGGGAAAATCCAAAAGAACTCGAAATGAATACAA
GAATGATTTAATTCTTATGTTAAAATATATTAAAGTTATAAAATATGATATTAATACGAATGGTATAGAGAATGTGGATA
TCTCAGATATTGATAATGATTTTATAAAAGCCATATCTCTTGAAGATTTATATATTTTTTTAGAATACTGTGAAGATGAA
AGACGAAACGGAGCATATTCCCGTGCAAGAAAAGTTGCTGCTATACGCTCATTTTTTAATTATCTTACTACGAAAAAAAA
GATATTAGATTACAACCCAGCGCAGGAGCTGGAAAAACCTAAGCTTCCAAAACGTAATCCTGTTTATCTAACTATAGGAC
AAGCCAACACATTTTTGTCTGGAATAAAAATGAACAAACATTACTATAGAAATACCTGTATAGTCACCTTGTTTTTAAAT
TGCGGTATGAGAGTATCTGAGTTATGTAATATAAATATTAATTCTATAAAAAACGATATGATATCAATAATCGGAAAGGG
AGATAAAGAGCGTACTGTTTATTTAAATGATATGTGTATAGATGCAATTAATAAATACATAGAGAAGGAACGTTCACTAC
AGAAAAATATAAAATGCCAACAAGCTTTATTTATATCTCAAAAAGGAACTCGAATAAGTGTGCGAACTATCGAAAACCTA
GTAAAAAAAATAAATGAAGATTCAAAGCTTAATATAAATAAACTCACTCCCCACAAATTACGTCACACATTTGCTACAAC
AATGTATCAAGCAGGAACAGACATTATTAGTTTGCAGCAGTTACTAGGACATAGTAATGTTTCAACAACGCAAATATATA
CGCATGTTACGGATGATAGATTAAGAGAAGCCACAAATAAAAATCCTTTCAATATTCAATTTAATAAGAAGAAATCTATA
AAAGAACAATAA

Upstream 100 bases:

>100_bases
ATAAATTTGTCGTCATTTTATGGTATTATATAGTGTATGATAGTTATTAGTTTAGCTGTTATTCCAAATACCGAAGATTG
AGGTGATTTAATTGAATAAA

Downstream 100 bases:

>100_bases
AAAACTCCATAATTTTCTCTATATAGGATATTATTTCTGTACATAAGTATACAAAAGAAAAGGGTTGAATTGAGTATGAT
TTTATCATTCAGTATATTTT

Product: site-specific tyrosine recombinase XerC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 323; Mature: 322

Protein sequence:

>323_residues
MPMTLTGFLIYMTNIKGKSKRTRNEYKNDLILMLKYIKVIKYDINTNGIENVDISDIDNDFIKAISLEDLYIFLEYCEDE
RRNGAYSRARKVAAIRSFFNYLTTKKKILDYNPAQELEKPKLPKRNPVYLTIGQANTFLSGIKMNKHYYRNTCIVTLFLN
CGMRVSELCNININSIKNDMISIIGKGDKERTVYLNDMCIDAINKYIEKERSLQKNIKCQQALFISQKGTRISVRTIENL
VKKINEDSKLNINKLTPHKLRHTFATTMYQAGTDIISLQQLLGHSNVSTTQIYTHVTDDRLREATNKNPFNIQFNKKKSI
KEQ

Sequences:

>Translated_323_residues
MPMTLTGFLIYMTNIKGKSKRTRNEYKNDLILMLKYIKVIKYDINTNGIENVDISDIDNDFIKAISLEDLYIFLEYCEDE
RRNGAYSRARKVAAIRSFFNYLTTKKKILDYNPAQELEKPKLPKRNPVYLTIGQANTFLSGIKMNKHYYRNTCIVTLFLN
CGMRVSELCNININSIKNDMISIIGKGDKERTVYLNDMCIDAINKYIEKERSLQKNIKCQQALFISQKGTRISVRTIENL
VKKINEDSKLNINKLTPHKLRHTFATTMYQAGTDIISLQQLLGHSNVSTTQIYTHVTDDRLREATNKNPFNIQFNKKKSI
KEQ
>Mature_322_residues
PMTLTGFLIYMTNIKGKSKRTRNEYKNDLILMLKYIKVIKYDINTNGIENVDISDIDNDFIKAISLEDLYIFLEYCEDER
RNGAYSRARKVAAIRSFFNYLTTKKKILDYNPAQELEKPKLPKRNPVYLTIGQANTFLSGIKMNKHYYRNTCIVTLFLNC
GMRVSELCNININSIKNDMISIIGKGDKERTVYLNDMCIDAINKYIEKERSLQKNIKCQQALFISQKGTRISVRTIENLV
KKINEDSKLNINKLTPHKLRHTFATTMYQAGTDIISLQQLLGHSNVSTTQIYTHVTDDRLREATNKNPFNIQFNKKKSIK
EQ

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG0582

COG function: function code L; Integrase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=307, Percent_Identity=30.2931596091205, Blast_Score=147, Evalue=8e-37,
Organism=Escherichia coli, GI1790244, Length=216, Percent_Identity=33.7962962962963, Blast_Score=130, Evalue=1e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 37542; Mature: 37411

Theoretical pI: Translated: 10.02; Mature: 10.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPMTLTGFLIYMTNIKGKSKRTRNEYKNDLILMLKYIKVIKYDINTNGIENVDISDIDND
CCEEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCHH
FIKAISLEDLYIFLEYCEDERRNGAYSRARKVAAIRSFFNYLTTKKKILDYNPAQELEKP
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCC
KLPKRNPVYLTIGQANTFLSGIKMNKHYYRNTCIVTLFLNCGMRVSELCNININSIKNDM
CCCCCCCEEEEECCCHHHHHHEECCCHHHHHHHEEEEEHHCCCCHHHHHCCCHHHHHHHH
ISIIGKGDKERTVYLNDMCIDAINKYIEKERSLQKNIKCQQALFISQKGTRISVRTIENL
HHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCHHHHHEEECCCCEEEHHHHHHH
VKKINEDSKLNINKLTPHKLRHTFATTMYQAGTDIISLQQLLGHSNVSTTQIYTHVTDDR
HHHCCCCCCEEECCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCEEEEEECCHHH
LREATNKNPFNIQFNKKKSIKEQ
HHHHCCCCCEEEEECCCCCCCCC
>Mature Secondary Structure 
PMTLTGFLIYMTNIKGKSKRTRNEYKNDLILMLKYIKVIKYDINTNGIENVDISDIDND
CEEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCHH
FIKAISLEDLYIFLEYCEDERRNGAYSRARKVAAIRSFFNYLTTKKKILDYNPAQELEKP
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCC
KLPKRNPVYLTIGQANTFLSGIKMNKHYYRNTCIVTLFLNCGMRVSELCNININSIKNDM
CCCCCCCEEEEECCCHHHHHHEECCCHHHHHHHEEEEEHHCCCCHHHHHCCCHHHHHHHH
ISIIGKGDKERTVYLNDMCIDAINKYIEKERSLQKNIKCQQALFISQKGTRISVRTIENL
HHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCHHHHHEEECCCCEEEHHHHHHH
VKKINEDSKLNINKLTPHKLRHTFATTMYQAGTDIISLQQLLGHSNVSTTQIYTHVTDDR
HHHCCCCCCEEECCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCEEEEEECCHHH
LREATNKNPFNIQFNKKKSIKEQ
HHHHCCCCCEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]