Click here to switch to the map view.

The map label for this gene is Not Available

Identifier: 15004780

GI number: 15004780

Start: 80094

End: 80870

Strand: Direct

Name: Not Available

Synonym: CA_P0076

Alternate gene names: 15004780

Gene position: 80094-80870 (Clockwise)

Preceding gene: 15004778

Following gene: 15004784

Centisome position: 41.72

GC content: 27.54

Gene sequence:

>777_bases
ATGCTAGAGAAAAGAAGCAAAAAAATAAATATAATAAAACGTTTATTTCTATATATCTTAGTATTTGCTGCTGTTTTTGG
TGGAATTGTTTATCTAAAATATGCTCCGACTGTTAAGGCTCTACATAATAGTGCAGCATTAAAAGTAAATAATTGTTCAG
AGATTACTTTTAAGAATAAATCTATGGATTTGAATAACGGTAAATTAATATATCTAAAATCAAATGAAATTCCTGAAGAA
GTAAAAAATGCTTTTATTGCTGTTGAAGATAGGAATTTTTATAAGCATGGAGGTATAAGTGTAGAAGCTGTTTTTAGAGC
TGTTTATTCGTTCTTTACAGATGGAGGTAAAATAACTCAGGGTGGAAGTACTATAACTCAACAGTTATCAAGAAATGTGT
TTTTAAATTTTAATAAGAATTACAAAAGAAAATTAGAAGAAATGTTTATTGCTAGTGATCTTGAAGAGAAATTCACAAAA
GATCAAATACTGGAATTCTATATAAATAATATTAATTTTAGCAATGGTGCATATGGTATTGAGGCAGCTTCTGAAAAATA
TTTCAGCACAGAATGCAGCAAATTAAATCTTTCTCAAATATGTTTATTAGCAGCTATTCCTAATGATCCAGAGTATTATA
ATCCCTTGGTACATTTGAATAATACTTTACAGAGAAGAAATTTAATACTGGAAAAGATGAAGGAAAATGACTACATAACG
GACAAACAATATAAGGAAGCTGTAAACTACAAAATAGTTTTAAATCCTAAAGATTAG

Upstream 100 bases:

>100_bases
AGGTTTATAGCTTTTATACTAAAAAAGGAGAAAAGTTTAAGAAAATAAGGTATACTAAATTTAATATTAAATTGTATTGC
TATATTGAAAGGAATATAAA

Downstream 100 bases:

>100_bases
TTAGGAATTTTAGTATTTTATATTATCTATTGCAGCCTTTAAAATAGCTAAAAACTTATCTATATTTTGCGGATAGATAA
GTTTTTTTATCAATAGATTA

Product: penicillin binding protein 1A

Products: NA

Alternate protein names: PBP-1F; Penicillin-binding protein F [H]

Number of amino acids: Translated: 258; Mature: 258

Protein sequence:

>258_residues
MLEKRSKKINIIKRLFLYILVFAAVFGGIVYLKYAPTVKALHNSAALKVNNCSEITFKNKSMDLNNGKLIYLKSNEIPEE
VKNAFIAVEDRNFYKHGGISVEAVFRAVYSFFTDGGKITQGGSTITQQLSRNVFLNFNKNYKRKLEEMFIASDLEEKFTK
DQILEFYINNINFSNGAYGIEAASEKYFSTECSKLNLSQICLLAAIPNDPEYYNPLVHLNNTLQRRNLILEKMKENDYIT
DKQYKEAVNYKIVLNPKD

Sequences:

>Translated_258_residues
MLEKRSKKINIIKRLFLYILVFAAVFGGIVYLKYAPTVKALHNSAALKVNNCSEITFKNKSMDLNNGKLIYLKSNEIPEE
VKNAFIAVEDRNFYKHGGISVEAVFRAVYSFFTDGGKITQGGSTITQQLSRNVFLNFNKNYKRKLEEMFIASDLEEKFTK
DQILEFYINNINFSNGAYGIEAASEKYFSTECSKLNLSQICLLAAIPNDPEYYNPLVHLNNTLQRRNLILEKMKENDYIT
DKQYKEAVNYKIVLNPKD
>Mature_258_residues
MLEKRSKKINIIKRLFLYILVFAAVFGGIVYLKYAPTVKALHNSAALKVNNCSEITFKNKSMDLNNGKLIYLKSNEIPEE
VKNAFIAVEDRNFYKHGGISVEAVFRAVYSFFTDGGKITQGGSTITQQLSRNVFLNFNKNYKRKLEEMFIASDLEEKFTK
DQILEFYINNINFSNGAYGIEAASEKYFSTECSKLNLSQICLLAAIPNDPEYYNPLVHLNNTLQRRNLILEKMKENDYIT
DKQYKEAVNYKIVLNPKD

Specific function: Cell wall formation. May be involved in outgrowth of the germinated spore or it could function in the synthesis of the germ cell wall [H]

COG id: COG0744

COG function: function code M; Membrane carboxypeptidase (penicillin-binding protein)

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the transpeptidase family [H]

Homologues:

Organism=Escherichia coli, GI87082258, Length=179, Percent_Identity=40.7821229050279, Blast_Score=150, Evalue=6e-38,
Organism=Escherichia coli, GI1786343, Length=167, Percent_Identity=34.7305389221557, Blast_Score=108, Evalue=5e-25,
Organism=Escherichia coli, GI1788867, Length=174, Percent_Identity=32.183908045977, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1789601, Length=235, Percent_Identity=28.936170212766, Blast_Score=96, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001264
- InterPro:   IPR011816
- InterPro:   IPR001460 [H]

Pfam domain/function: PF00912 Transgly; PF00905 Transpeptidase [H]

EC number: 2.4.2.-; 3.4.-.- [C]

Molecular weight: Translated: 29686; Mature: 29686

Theoretical pI: Translated: 9.39; Mature: 9.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEKRSKKINIIKRLFLYILVFAAVFGGIVYLKYAPTVKALHNSAALKVNNCSEITFKNK
CCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCHHHHHHCCCEEEECCCCEEEEECC
SMDLNNGKLIYLKSNEIPEEVKNAFIAVEDRNFYKHGGISVEAVFRAVYSFFTDGGKITQ
CCCCCCCEEEEEECCCCCHHHHCCEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCEEEC
GGSTITQQLSRNVFLNFNKNYKRKLEEMFIASDLEEKFTKDQILEFYINNINFSNGAYGI
CCHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
EAASEKYFSTECSKLNLSQICLLAAIPNDPEYYNPLVHLNNTLQRRNLILEKMKENDYIT
CHHCHHHHHCCCCCCCHHHEEEEEECCCCHHHHCCHHHHCHHHHHHHHHHHHHHCCCCCC
DKQYKEAVNYKIVLNPKD
CHHHHHHCCEEEEECCCC
>Mature Secondary Structure
MLEKRSKKINIIKRLFLYILVFAAVFGGIVYLKYAPTVKALHNSAALKVNNCSEITFKNK
CCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCHHHHHHCCCEEEECCCCEEEEECC
SMDLNNGKLIYLKSNEIPEEVKNAFIAVEDRNFYKHGGISVEAVFRAVYSFFTDGGKITQ
CCCCCCCEEEEEECCCCCHHHHCCEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCEEEC
GGSTITQQLSRNVFLNFNKNYKRKLEEMFIASDLEEKFTKDQILEFYINNINFSNGAYGI
CCHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
EAASEKYFSTECSKLNLSQICLLAAIPNDPEYYNPLVHLNNTLQRRNLILEKMKENDYIT
CHHCHHHHHCCCCCCCHHHEEEEEECCCCHHHHCCHHHHCHHHHHHHHHHHHHHCCCCCC
DKQYKEAVNYKIVLNPKD
CHHHHHHCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferases; Acyltransferases; Aminoacyltransferases [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377; 8335642; 1459957 [H]