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The map label for this gene is fsr [H]

Identifier: 150008171

GI number: 150008171

Start: 1801430

End: 1801879

Strand: Reverse

Name: fsr [H]

Synonym: BDI_1537

Alternate gene names: 150008171

Gene position: 1801879-1801430 (Counterclockwise)

Preceding gene: 150008172

Following gene: 150008170

Centisome position: 37.45

GC content: 46.89

Gene sequence:

>450_bases
ATGGAGCAGGTTCCTAAACAGCAGCCGGTAAATAAAACAGCATTCCGGGTATTAGTGGCGTTAAGCGTTACGCATTGTTT
GAATGATTCGTTGCAATCCGTTATCTCGGCGGTTTATCCACTTTTCAAGGATGATTTAGCGTTGAGCTTCGCCCAAATCG
GGTTGATTACGCTTGTTTATCAATTATCCGCTTCTGTTTTCCAGCCTATAACCGGTTTGGTTTTTGATAAGCGTCCCGTG
GCTTGGTCGTTACCTATTGGTATGAGTTTTACGTTGGTCGGCTTGTTGAATCTCGCTTTTTCCTCTACGCTCCATTGGGT
CTTGATCTCCGTATTCTTGATAGGTATCGGGTCTTCGGTTTTGCATCCGGAAGCGTCCCGGATTACCTCGCTAGCGTCGG
GAGGGCGTAGGGGATTGGCACAATCGCTTTTTCAAGTGGGTGGTAATTAG

Upstream 100 bases:

>100_bases
AAATAGGCTCTTAGGGTTTGTTTTTCTAGAAATTAGCTAACTTTTTGTGTGGTTTTTGAAATGTTAATGAGCATGAGGTT
AAATAGAAATATGGACAGTC

Downstream 100 bases:

>100_bases
GGCGGATCGTTAGGTCCGCTACTGGTTGCTTTATTGGTGGCGCCTTATGGACGGACTCATATCGCTTTGTTTTCTATACT
GGCATTCGTCGCTATTTTGG

Product: putative fosmidomycin resistance protein

Products: fosmidomycin [Periplasm]; Proton [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 149; Mature: 149

Protein sequence:

>149_residues
MEQVPKQQPVNKTAFRVLVALSVTHCLNDSLQSVISAVYPLFKDDLALSFAQIGLITLVYQLSASVFQPITGLVFDKRPV
AWSLPIGMSFTLVGLLNLAFSSTLHWVLISVFLIGIGSSVLHPEASRITSLASGGRRGLAQSLFQVGGN

Sequences:

>Translated_149_residues
MEQVPKQQPVNKTAFRVLVALSVTHCLNDSLQSVISAVYPLFKDDLALSFAQIGLITLVYQLSASVFQPITGLVFDKRPV
AWSLPIGMSFTLVGLLNLAFSSTLHWVLISVFLIGIGSSVLHPEASRITSLASGGRRGLAQSLFQVGGN
>Mature_149_residues
MEQVPKQQPVNKTAFRVLVALSVTHCLNDSLQSVISAVYPLFKDDLALSFAQIGLITLVYQLSASVFQPITGLVFDKRPV
AWSLPIGMSFTLVGLLNLAFSSTLHWVLISVFLIGIGSSVLHPEASRITSLASGGRRGLAQSLFQVGGN

Specific function: Confers the resistance against fosmidomycin [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily [H]

Homologues:

Organism=Escherichia coli, GI1786686, Length=138, Percent_Identity=55.0724637681159, Blast_Score=160, Evalue=3e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 16012; Mature: 16012

Theoretical pI: Translated: 9.83; Mature: 9.83

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQVPKQQPVNKTAFRVLVALSVTHCLNDSLQSVISAVYPLFKDDLALSFAQIGLITLVY
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QLSASVFQPITGLVFDKRPVAWSLPIGMSFTLVGLLNLAFSSTLHWVLISVFLIGIGSSV
HHHHHHHHHHHHHHCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
LHPEASRITSLASGGRRGLAQSLFQVGGN
CCCCHHHHHHHHCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MEQVPKQQPVNKTAFRVLVALSVTHCLNDSLQSVISAVYPLFKDDLALSFAQIGLITLVY
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QLSASVFQPITGLVFDKRPVAWSLPIGMSFTLVGLLNLAFSSTLHWVLISVFLIGIGSSV
HHHHHHHHHHHHHHCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
LHPEASRITSLASGGRRGLAQSLFQVGGN
CCCCHHHHHHHHCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: fosmidomycin [Cytoplasm]; Proton [Periplasm] [C]

Specific reaction: fosmidomycin [Cytoplasm] + Proton [Periplasm] = fosmidomycin [Periplasm] + Proton [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8917080; 9278503 [H]