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The map label for this gene is ltaE [H]

Identifier: 150008139

GI number: 150008139

Start: 1756336

End: 1757358

Strand: Reverse

Name: ltaE [H]

Synonym: BDI_1505

Alternate gene names: 150008139

Gene position: 1757358-1756336 (Counterclockwise)

Preceding gene: 150008140

Following gene: 150008138

Centisome position: 36.53

GC content: 51.71

Gene sequence:

>1023_bases
ATGAGAAGTTTCGCTAGTGACAACAATTCCGGCGTGCATCCCCGGGTAATGGATGCGATCATCAAGGCAAATGATAATCA
TGCGGTTGGATATGGTGATGATCCTTGGACAGAGGCCGCTACGAGTAAGATACAAGAAGTGTTCGGCAAGGATGCTTCTC
CTTTTTTCGTGTTTAACGGGACGGGGGCGAACTCCGTGGCCCTGCAAGCCGTGACCCGTCCGTTTAATAGCATCCTGTGC
GCCGAGACCGCCCATATCAACGTAGACGAATGTGGAGCCCCCGCACGGATGACCGGTTGCGCCATCGTCACGATTCCTAC
GACGGATGGTAAGCTGACACCGGAATTGATCCGTCCCCATCTGAAGAACTTCGGGGTTTGCCACCATTCGCAACCCAAGG
CCGTTTATATCTCCCAAGTATCGGAATTAGGTACGATCTATACGATAGAGGAAGTGAAAGCGATCGCCGATCTCTTACAT
TCGTACGATATGTATCTGCATATGGACGGAGCACGCTTGGCGAACGCCTGCGCTTACCTGAATTGCTCGATGCGCCAAGT
GACTGTAGACGCAGGCGTGGATATCTTGAGCTTCGGAGGCACGAAAAACGGTATGATGATGGGAGAGGCCGTGGTCTCGT
TCCGCCCGGAGATCACGGAGAACCTGCGATTTTACCGGAAGCAATCCGCCCAGCTAGCCTCGAAGCTACGTTATCTCTCC
GCCCAGTTCATCCCTTATCTGGAAAATAACCTCTGGTTGGAGAACGCTATGAAAGCGAATATCAGCGCCGCCAAGCTAGC
GGACGTGCTACGACAATACCCGGAAATTCATTTTACGCAGAAGATCGAGTCCAACCAGCTCTTCTTCACGATCCCTGCCG
AGGCGTTGAGGAAGTTGCAAGATAAATATTTCTTCTATATGTGGAACGAGGAGATCAACGAGGCCCGTCTCGTTACCTCT
TGGGATACTTCCGGCGAGGATATCGCTGAGTTCGAGCAGTCATTGAAAGAGATATTCGGTTAA

Upstream 100 bases:

>100_bases
ATACAAATAAGAATAACATAATGGATAGCGATAAATAGTTACTTGGATATCCTCATTCTCATCTTAAATCCGTACTTTTG
GCGAAAAATCAGATTTAAAG

Downstream 100 bases:

>100_bases
GGTATAGATATAAAATGAATATAAACATTAGATCGAATCCTATGAGGAAATGGTTTATTTGGGCGATCGTTATGATCGGA
TGTTTGCCCATAAATAAGGC

Product: L-threonine aldolase

Products: NA

Alternate protein names: Low specificity L-TA [H]

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MRSFASDNNSGVHPRVMDAIIKANDNHAVGYGDDPWTEAATSKIQEVFGKDASPFFVFNGTGANSVALQAVTRPFNSILC
AETAHINVDECGAPARMTGCAIVTIPTTDGKLTPELIRPHLKNFGVCHHSQPKAVYISQVSELGTIYTIEEVKAIADLLH
SYDMYLHMDGARLANACAYLNCSMRQVTVDAGVDILSFGGTKNGMMMGEAVVSFRPEITENLRFYRKQSAQLASKLRYLS
AQFIPYLENNLWLENAMKANISAAKLADVLRQYPEIHFTQKIESNQLFFTIPAEALRKLQDKYFFYMWNEEINEARLVTS
WDTSGEDIAEFEQSLKEIFG

Sequences:

>Translated_340_residues
MRSFASDNNSGVHPRVMDAIIKANDNHAVGYGDDPWTEAATSKIQEVFGKDASPFFVFNGTGANSVALQAVTRPFNSILC
AETAHINVDECGAPARMTGCAIVTIPTTDGKLTPELIRPHLKNFGVCHHSQPKAVYISQVSELGTIYTIEEVKAIADLLH
SYDMYLHMDGARLANACAYLNCSMRQVTVDAGVDILSFGGTKNGMMMGEAVVSFRPEITENLRFYRKQSAQLASKLRYLS
AQFIPYLENNLWLENAMKANISAAKLADVLRQYPEIHFTQKIESNQLFFTIPAEALRKLQDKYFFYMWNEEINEARLVTS
WDTSGEDIAEFEQSLKEIFG
>Mature_340_residues
MRSFASDNNSGVHPRVMDAIIKANDNHAVGYGDDPWTEAATSKIQEVFGKDASPFFVFNGTGANSVALQAVTRPFNSILC
AETAHINVDECGAPARMTGCAIVTIPTTDGKLTPELIRPHLKNFGVCHHSQPKAVYISQVSELGTIYTIEEVKAIADLLH
SYDMYLHMDGARLANACAYLNCSMRQVTVDAGVDILSFGGTKNGMMMGEAVVSFRPEITENLRFYRKQSAQLASKLRYLS
AQFIPYLENNLWLENAMKANISAAKLADVLRQYPEIHFTQKIESNQLFFTIPAEALRKLQDKYFFYMWNEEINEARLVTS
WDTSGEDIAEFEQSLKEIFG

Specific function: Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde. Can also act on L-erythro- phenylserine, L-threo-phenylserine, L-beta-3,4- methylenedioxyphenylserine and L-beta-3,4-dihydroxyphenylserine [H]

COG id: COG2008

COG function: function code E; Threonine aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the threonine aldolase family [H]

Homologues:

Organism=Escherichia coli, GI1787095, Length=306, Percent_Identity=27.4509803921569, Blast_Score=67, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI193206522, Length=160, Percent_Identity=29.375, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI193206520, Length=160, Percent_Identity=29.375, Blast_Score=65, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI193206524, Length=160, Percent_Identity=29.375, Blast_Score=65, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001597
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF01212 Beta_elim_lyase [H]

EC number: =4.1.2.5 [H]

Molecular weight: Translated: 37934; Mature: 37934

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSFASDNNSGVHPRVMDAIIKANDNHAVGYGDDPWTEAATSKIQEVFGKDASPFFVFNG
CCCCCCCCCCCCCHHHHHHHHHCCCCCEECCCCCCHHHHHHHHHHHHHCCCCCCEEEEEC
TGANSVALQAVTRPFNSILCAETAHINVDECGAPARMTGCAIVTIPTTDGKLTPELIRPH
CCCCHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCEECCEEEEEEECCCCCCCHHHHHHH
LKNFGVCHHSQPKAVYISQVSELGTIYTIEEVKAIADLLHSYDMYLHMDGARLANACAYL
HHHCCCCCCCCCCEEHHHHHHHCCCEEEHHHHHHHHHHHHHCCEEEEECCHHHHHHHHHE
NCSMRQVTVDAGVDILSFGGTKNGMMMGEAVVSFRPEITENLRFYRKQSAQLASKLRYLS
ECCCEEEEECCCCEEEECCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
AQFIPYLENNLWLENAMKANISAAKLADVLRQYPEIHFTQKIESNQLFFTIPAEALRKLQ
HHHHHHHCCCEEHHHHHHCCCHHHHHHHHHHHCCCCEEEEEECCCEEEEEECHHHHHHHH
DKYFFYMWNEEINEARLVTSWDTSGEDIAEFEQSLKEIFG
HCEEEEEECCCCCCEEEEEECCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRSFASDNNSGVHPRVMDAIIKANDNHAVGYGDDPWTEAATSKIQEVFGKDASPFFVFNG
CCCCCCCCCCCCCHHHHHHHHHCCCCCEECCCCCCHHHHHHHHHHHHHCCCCCCEEEEEC
TGANSVALQAVTRPFNSILCAETAHINVDECGAPARMTGCAIVTIPTTDGKLTPELIRPH
CCCCHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCEECCEEEEEEECCCCCCCHHHHHHH
LKNFGVCHHSQPKAVYISQVSELGTIYTIEEVKAIADLLHSYDMYLHMDGARLANACAYL
HHHCCCCCCCCCCEEHHHHHHHCCCEEEHHHHHHHHHHHHHCCEEEEECCHHHHHHHHHE
NCSMRQVTVDAGVDILSFGGTKNGMMMGEAVVSFRPEITENLRFYRKQSAQLASKLRYLS
ECCCEEEEECCCCEEEECCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
AQFIPYLENNLWLENAMKANISAAKLADVLRQYPEIHFTQKIESNQLFFTIPAEALRKLQ
HHHHHHHCCCEEHHHHHHCCCHHHHHHHHHHHCCCCEEEEEECCCEEEEEECHHHHHHHH
DKYFFYMWNEEINEARLVTSWDTSGEDIAEFEQSLKEIFG
HCEEEEEECCCCCCEEEEEECCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9464392 [H]