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The map label for this gene is xanP [H]

Identifier: 150008137

GI number: 150008137

Start: 1753101

End: 1754426

Strand: Reverse

Name: xanP [H]

Synonym: BDI_1503

Alternate gene names: 150008137

Gene position: 1754426-1753101 (Counterclockwise)

Preceding gene: 150008138

Following gene: 150008136

Centisome position: 36.46

GC content: 52.34

Gene sequence:

>1326_bases
ATGGATACGGATTTGATTTACGGGATCGATGACCGTCCGCCTTTGAAAGAGACGCTTTTTGCCGCCATCCAGCATCTACT
GGCTATTTTCGTGGCGATCATAACACCTCCCTTGATTATCGCCGGGGCGCTGAAACTGGATCTGGAGACGACCGGTTTCT
TGGTTTCCATGGCCCTATTCGCCTCCGGGGTATCCACATTCGTTCAATGTCGTAAATTAGGACCGGTCGGGGCGGGGCTG
CTATGTATCCAAGGAACCAGCTTCTCGTTTATCGGCCCGATTATCACGGCTGGTTTGGCGGGAGGGCTTCCCCTTATTTT
CGGCGTTTGTATCGCCGCCTCTCCGGTAGAGATGATCGTGAGCCGTACTTTTAAGTATCTGCGCTCGGTGATTACTCCCT
TGGTATCGGGTATCGTGGTGTTGCTCATCGGCTTGAGCTTGATCAAGGTAGGAGTGGTCGCTTGCGGCGGGGGGTATACG
GCTATGGATAACGGTACGTTCGGTAGTTTGCGTAATATTGGGGTAGCTGTGTGCGTCTTGTTGAGTGTCTTGTTCTTCAA
TCGTTGTAAGAACAAGTACTTGCGGATGAGTTCCATCGTACTGGGGTTGTGTATCGGTTATGCGATCGCTTTCGCCATGG
GGATGGTGGATATGGAGGCTGTCTCCTCGCAAAACCTGAGAGGGTTTAATATCCCGGTTCCTTTCAAATATGGATTGGAT
TTTAATATCTCTTCATTCGTGGCGATCGCATTGATCTATCTGATCACGGCGATCGAGGCTACGGGGGATATTACGGCCAA
CTCGATGATATCGGGAAAATCGATCGAGGGAGAAGGGTACCTGAAGCGAGTCTCCGGCGGGGTGCTGGCGGATGGGGTGA
ACTCGTTTATCTCCGGTGTTTTTAACTCTTTCCCGAACTCTATCTTCGCCCAGAATAACGGGATCATCCAGCTGACGGGA
GTCGCCAGCCGGTACGTAGGGTATTATATCGCAGGTATGCTGATCCTGTTGGGATTATTCCCGGTTGTCGGCGTTATCTT
CTCCTTGATGCCCGATCCGGTGCTGGGAGGGGCTACCCTGCTGATGTTCGGTACGGTGGCGGCGGCAGGTATCCGTATTA
TCGCCGCCCAAGATATCAACCGGAAGGCCACGTTGGTGTTGGCGGTTAGTTTGTCCTTGGGGCTGGGGGTGGAGCTGATG
CCGGATATTTTAGGGGCCGCCCCTCAGGTGATCCGTGGCATTTTCTCCTCCGGTATTACGACGGGGGGCTTGACGGCCAT
TCTGGCGAATTTATTTATACGTGTAAAAGAAGATCAAACAGAATAA

Upstream 100 bases:

>100_bases
CTACGGTGATGGTATTGCGGAAGAAAGGAAACGAGATGAGTGTACGGGTGTTGAACGCAAGAGGAGAGACCTTATTAGAC
TTGAAATTATAAGAGACAGT

Downstream 100 bases:

>100_bases
CAAATTATGGAATTATTGAAGCAACGCATCTTGCAAGACGGCCGCTGTTATCCCGGCGGTATCCTTAAAGTGGATAGTTT
TATCAACCATCAAATGGACC

Product: putative purine permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 441; Mature: 441

Protein sequence:

>441_residues
MDTDLIYGIDDRPPLKETLFAAIQHLLAIFVAIITPPLIIAGALKLDLETTGFLVSMALFASGVSTFVQCRKLGPVGAGL
LCIQGTSFSFIGPIITAGLAGGLPLIFGVCIAASPVEMIVSRTFKYLRSVITPLVSGIVVLLIGLSLIKVGVVACGGGYT
AMDNGTFGSLRNIGVAVCVLLSVLFFNRCKNKYLRMSSIVLGLCIGYAIAFAMGMVDMEAVSSQNLRGFNIPVPFKYGLD
FNISSFVAIALIYLITAIEATGDITANSMISGKSIEGEGYLKRVSGGVLADGVNSFISGVFNSFPNSIFAQNNGIIQLTG
VASRYVGYYIAGMLILLGLFPVVGVIFSLMPDPVLGGATLLMFGTVAAAGIRIIAAQDINRKATLVLAVSLSLGLGVELM
PDILGAAPQVIRGIFSSGITTGGLTAILANLFIRVKEDQTE

Sequences:

>Translated_441_residues
MDTDLIYGIDDRPPLKETLFAAIQHLLAIFVAIITPPLIIAGALKLDLETTGFLVSMALFASGVSTFVQCRKLGPVGAGL
LCIQGTSFSFIGPIITAGLAGGLPLIFGVCIAASPVEMIVSRTFKYLRSVITPLVSGIVVLLIGLSLIKVGVVACGGGYT
AMDNGTFGSLRNIGVAVCVLLSVLFFNRCKNKYLRMSSIVLGLCIGYAIAFAMGMVDMEAVSSQNLRGFNIPVPFKYGLD
FNISSFVAIALIYLITAIEATGDITANSMISGKSIEGEGYLKRVSGGVLADGVNSFISGVFNSFPNSIFAQNNGIIQLTG
VASRYVGYYIAGMLILLGLFPVVGVIFSLMPDPVLGGATLLMFGTVAAAGIRIIAAQDINRKATLVLAVSLSLGLGVELM
PDILGAAPQVIRGIFSSGITTGGLTAILANLFIRVKEDQTE
>Mature_441_residues
MDTDLIYGIDDRPPLKETLFAAIQHLLAIFVAIITPPLIIAGALKLDLETTGFLVSMALFASGVSTFVQCRKLGPVGAGL
LCIQGTSFSFIGPIITAGLAGGLPLIFGVCIAASPVEMIVSRTFKYLRSVITPLVSGIVVLLIGLSLIKVGVVACGGGYT
AMDNGTFGSLRNIGVAVCVLLSVLFFNRCKNKYLRMSSIVLGLCIGYAIAFAMGMVDMEAVSSQNLRGFNIPVPFKYGLD
FNISSFVAIALIYLITAIEATGDITANSMISGKSIEGEGYLKRVSGGVLADGVNSFISGVFNSFPNSIFAQNNGIIQLTG
VASRYVGYYIAGMLILLGLFPVVGVIFSLMPDPVLGGATLLMFGTVAAAGIRIIAAQDINRKATLVLAVSLSLGLGVELM
PDILGAAPQVIRGIFSSGITTGGLTAILANLFIRVKEDQTE

Specific function: Specific, proton motive force-dependent high-affinity transporter for xanthine [H]

COG id: COG2233

COG function: function code F; Xanthine/uracil permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. Nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) subfamily [H]

Homologues:

Organism=Homo sapiens, GI44680148, Length=504, Percent_Identity=23.4126984126984, Blast_Score=90, Evalue=5e-18,
Organism=Homo sapiens, GI40316845, Length=504, Percent_Identity=23.4126984126984, Blast_Score=90, Evalue=5e-18,
Organism=Homo sapiens, GI44680145, Length=483, Percent_Identity=23.6024844720497, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI44680143, Length=487, Percent_Identity=23.4086242299795, Blast_Score=78, Evalue=1e-14,
Organism=Escherichia coli, GI1790087, Length=446, Percent_Identity=50.2242152466368, Blast_Score=437, Evalue=1e-124,
Organism=Escherichia coli, GI87082178, Length=440, Percent_Identity=49.3181818181818, Blast_Score=371, Evalue=1e-104,
Organism=Escherichia coli, GI87082181, Length=425, Percent_Identity=31.0588235294118, Blast_Score=187, Evalue=9e-49,
Organism=Escherichia coli, GI1788843, Length=397, Percent_Identity=29.9748110831234, Blast_Score=110, Evalue=3e-25,
Organism=Escherichia coli, GI87081818, Length=405, Percent_Identity=24.9382716049383, Blast_Score=82, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17558856, Length=404, Percent_Identity=23.7623762376238, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006042
- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 46074; Mature: 46074

Theoretical pI: Translated: 8.01; Mature: 8.01

Prosite motif: PS01116 XANTH_URACIL_PERMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTDLIYGIDDRPPLKETLFAAIQHLLAIFVAIITPPLIIAGALKLDLETTGFLVSMALF
CCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHEECCCHHHHHHHHHHH
ASGVSTFVQCRKLGPVGAGLLCIQGTSFSFIGPIITAGLAGGLPLIFGVCIAASPVEMIV
HHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHH
SRTFKYLRSVITPLVSGIVVLLIGLSLIKVGVVACGGGYTAMDNGTFGSLRNIGVAVCVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCEECCCCCCHHHHHHHHHHHHH
LSVLFFNRCKNKYLRMSSIVLGLCIGYAIAFAMGMVDMEAVSSQNLRGFNIPVPFKYGLD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEECCCC
FNISSFVAIALIYLITAIEATGDITANSMISGKSIEGEGYLKRVSGGVLADGVNSFISGV
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHH
FNSFPNSIFAQNNGIIQLTGVASRYVGYYIAGMLILLGLFPVVGVIFSLMPDPVLGGATL
HHHCCCCEEECCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
LMFGTVAAAGIRIIAAQDINRKATLVLAVSLSLGLGVELMPDILGAAPQVIRGIFSSGIT
HHHHHHHHHCEEEEEECCCCCCEEEEEEEEHHHCCCHHHHHHHHCCCHHHHHHHHHCCCC
TGGLTAILANLFIRVKEDQTE
CCHHHHHHHHHHEEECCCCCC
>Mature Secondary Structure
MDTDLIYGIDDRPPLKETLFAAIQHLLAIFVAIITPPLIIAGALKLDLETTGFLVSMALF
CCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHEECCCHHHHHHHHHHH
ASGVSTFVQCRKLGPVGAGLLCIQGTSFSFIGPIITAGLAGGLPLIFGVCIAASPVEMIV
HHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHH
SRTFKYLRSVITPLVSGIVVLLIGLSLIKVGVVACGGGYTAMDNGTFGSLRNIGVAVCVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCEECCCCCCHHHHHHHHHHHHH
LSVLFFNRCKNKYLRMSSIVLGLCIGYAIAFAMGMVDMEAVSSQNLRGFNIPVPFKYGLD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEECCCC
FNISSFVAIALIYLITAIEATGDITANSMISGKSIEGEGYLKRVSGGVLADGVNSFISGV
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHH
FNSFPNSIFAQNNGIIQLTGVASRYVGYYIAGMLILLGLFPVVGVIFSLMPDPVLGGATL
HHHCCCCEEECCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
LMFGTVAAAGIRIIAAQDINRKATLVLAVSLSLGLGVELMPDILGAAPQVIRGIFSSGIT
HHHHHHHHHCEEEEEECCCCCCEEEEEEEEHHHCCCHHHHHHHHCCCHHHHHHHHHCCCC
TGGLTAILANLFIRVKEDQTE
CCHHHHHHHHHHEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]