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The map label for this gene is xpt

Identifier: 150008136

GI number: 150008136

Start: 1752528

End: 1753094

Strand: Reverse

Name: xpt

Synonym: BDI_1502

Alternate gene names: 150008136

Gene position: 1753094-1752528 (Counterclockwise)

Preceding gene: 150008137

Following gene: 150008135

Centisome position: 36.44

GC content: 47.44

Gene sequence:

>567_bases
ATGGAATTATTGAAGCAACGCATCTTGCAAGACGGCCGCTGTTATCCCGGCGGTATCCTTAAAGTGGATAGTTTTATCAA
CCATCAAATGGACCCGATGTTGATGTATAAGATCGCCGAGGAATTTATCCGTCGCTTTCAAGATCGTAAGATTAACAAGA
TCGTGACCATCGAGGCGAGCGGCATCGCCCCGGCCATTATGGTGGGTTATATCATGCAGCTGCCGGTGGTCTTCGTAAAG
AAGAAGAAACCGAAGACGATGGAGAACATGCTCTCTACCGTGGTCCATTCCTTCACGAAGGATCGTGACTATACGGTATG
TATCAGCAATAATTTCCTGACTCCGGAGGATCATATCCTGTTTATCGATGATTTCTTGGCTTACGGAAACGCCGCCATGG
GAATGGTCGAGTTGGCGGAGCAATCGGGAGCCGTGATCGAGGGTATGGGTTTTATTATAGAGAAGGCGTTTCAAGATGGT
GGGAACCTGCTACGTGAAAAGGGCATACGTGTGGAGAGCCTCGCCATTATCGATAATCTGGATGATTGTAAGATAACGGT
TCGTTAA

Upstream 100 bases:

>100_bases
CCGTGGCATTTTCTCCTCCGGTATTACGACGGGGGGCTTGACGGCCATTCTGGCGAATTTATTTATACGTGTAAAAGAAG
ATCAAACAGAATAACAAATT

Downstream 100 bases:

>100_bases
AGGAAAAGATATGGATGAGAGAATAAAAGAAAAGTTGATTAACCGTGCGAAGACGAATCCTTATGTGAATTTTCTGGGGA
TCGACTTCACGGTTATCGAG

Product: xanthine phosphoribosyltransferase

Products: NA

Alternate protein names: XPRTase

Number of amino acids: Translated: 188; Mature: 188

Protein sequence:

>188_residues
MELLKQRILQDGRCYPGGILKVDSFINHQMDPMLMYKIAEEFIRRFQDRKINKIVTIEASGIAPAIMVGYIMQLPVVFVK
KKKPKTMENMLSTVVHSFTKDRDYTVCISNNFLTPEDHILFIDDFLAYGNAAMGMVELAEQSGAVIEGMGFIIEKAFQDG
GNLLREKGIRVESLAIIDNLDDCKITVR

Sequences:

>Translated_188_residues
MELLKQRILQDGRCYPGGILKVDSFINHQMDPMLMYKIAEEFIRRFQDRKINKIVTIEASGIAPAIMVGYIMQLPVVFVK
KKKPKTMENMLSTVVHSFTKDRDYTVCISNNFLTPEDHILFIDDFLAYGNAAMGMVELAEQSGAVIEGMGFIIEKAFQDG
GNLLREKGIRVESLAIIDNLDDCKITVR
>Mature_188_residues
MELLKQRILQDGRCYPGGILKVDSFINHQMDPMLMYKIAEEFIRRFQDRKINKIVTIEASGIAPAIMVGYIMQLPVVFVK
KKKPKTMENMLSTVVHSFTKDRDYTVCISNNFLTPEDHILFIDDFLAYGNAAMGMVELAEQSGAVIEGMGFIIEKAFQDG
GNLLREKGIRVESLAIIDNLDDCKITVR

Specific function: Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis

COG id: COG0503

COG function: function code F; Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family. XPT subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): XPT_PARD8 (A6LC43)

Other databases:

- EMBL:   CP000140
- RefSeq:   YP_001302879.1
- ProteinModelPortal:   A6LC43
- SMR:   A6LC43
- STRING:   A6LC43
- GeneID:   5306655
- GenomeReviews:   CP000140_GR
- KEGG:   pdi:BDI_1502
- eggNOG:   COG0503
- HOGENOM:   HBG288993
- OMA:   ATVYSFT
- ProtClustDB:   PRK09219
- BioCyc:   PDIS435591:BDI_1502-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01184
- InterPro:   IPR000836
- InterPro:   IPR010079
- TIGRFAMs:   TIGR01744

Pfam domain/function: PF00156 Pribosyltran

EC number: =2.4.2.22

Molecular weight: Translated: 21311; Mature: 21311

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: PS00103 PUR_PYR_PR_TRANSFER

Important sites: BINDING 20-20 BINDING 27-27 BINDING 155-155

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
5.9 %Met     (Translated Protein)
7.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
5.9 %Met     (Mature Protein)
7.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELLKQRILQDGRCYPGGILKVDSFINHQMDPMLMYKIAEEFIRRFQDRKINKIVTIEAS
CHHHHHHHHHCCCCCCCCEEEHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEEC
GIAPAIMVGYIMQLPVVFVKKKKPKTMENMLSTVVHSFTKDRDYTVCISNNFLTPEDHIL
CCCHHHHHHHHHHCCHHEEECCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCEE
FIDDFLAYGNAAMGMVELAEQSGAVIEGMGFIIEKAFQDGGNLLREKGIRVESLAIIDNL
EEEHHHHHCCHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCC
DDCKITVR
CCCEEEEC
>Mature Secondary Structure
MELLKQRILQDGRCYPGGILKVDSFINHQMDPMLMYKIAEEFIRRFQDRKINKIVTIEAS
CHHHHHHHHHCCCCCCCCEEEHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEEC
GIAPAIMVGYIMQLPVVFVKKKKPKTMENMLSTVVHSFTKDRDYTVCISNNFLTPEDHIL
CCCHHHHHHHHHHCCHHEEECCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCEE
FIDDFLAYGNAAMGMVELAEQSGAVIEGMGFIIEKAFQDGGNLLREKGIRVESLAIIDNL
EEEHHHHHCCHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCC
DDCKITVR
CCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA