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The map label for this gene is metA

Identifier: 150008125

GI number: 150008125

Start: 1739654

End: 1740586

Strand: Reverse

Name: metA

Synonym: BDI_1490

Alternate gene names: 150008125

Gene position: 1740586-1739654 (Counterclockwise)

Preceding gene: 150008126

Following gene: 150008124

Centisome position: 36.18

GC content: 51.34

Gene sequence:

>933_bases
ATGCCATTAAATTTACAAAAGAACTTACCGGCTATCGAGCTGCTGAAGAAGGAACATATCTTCGTGATGGATTCCTTGCG
TGCGTCGGAGCAGGATATCCGCCCCCTTCGGGTAGTCGTATTGAATTTGATGCCCCTTAAGATAACGACCGAGACGGACT
TGGTTCGCCTCCTCAGTAATACACCCCTGCAAGTGGAACTTGATTTCATGAAGATCAAGGGACATACGCCGAAGAATACG
CCCATCGAGCATATGCAAGAATTTTATAAGGATTTCGATGAGATGGCGGATGATTTCTACGACGGGATGATCGTGACGGG
CGCTCCCGTGGAGCAGATGCCTTTCGAGGAAGTTAGTTATTGGGAGGAGATCACGCAGATATTCGATTGGGCCCGTACGC
ACGTTACCTCCACGCTCTATATCTGCTGGGCGGCGCAAGCGGGGCTATACCATTTCTATGGGGTGCCTAAATATGATTTG
CCGGCCAAGATGTTCGGTGTCTTCCGTCATTCGCTCCGGGAACCGTTTGTTCCGATCTTCCGGGGGTTCGATGACGAGTT
CTTCGTGCCTCATAGCCGTCATACCGAGATTCGCCGGGAGGATATCATGAAGGTGCCCGAGCTCACCTTATTGTCCGAGA
GCGAGGAATCCGGCGTCTATATGGCGATGGCTCGTGGCGGACGGGAATTCTTCATCACCGGCCATTCCGAGTATTCGCCC
TATACGCTGAATGATGAGTATATGCGTGATTTGGGGAAGGGATTGCCCATCAACAAGCCTCGTAATTATTACCGGAATAA
CGATCCGGCGCAAGGTCCGGTGGTACGTTGGCGGGGGCACGCGAACCTGCTGTTCACCAATTGGCTGAACTACTACGTAT
ACCAAGAGACCCCGTTCCGCCGGGAAGATATTAAAAAACTAGGAAGCTTGTAA

Upstream 100 bases:

>100_bases
ATGCACGAGGAGGACAACCCGGTGATCATGGTGGCGAAGTATAAGCGATAATGAGAAAATTCTCATTATCTTTGCGCTCA
TATAAAATCAGAGATAGAAA

Downstream 100 bases:

>100_bases
ATGAGAAAAGAACCCCGTTCGATAGAACTGTTATCTCCCGCTAAGGATCTGATTTGCGGCAGGGAGGCGATTAACCATGG
TGCCGATGCCGTGTATATCG

Product: homoserine O-succinyltransferase

Products: NA

Alternate protein names: Homoserine O-transsuccinylase; HTS

Number of amino acids: Translated: 310; Mature: 309

Protein sequence:

>310_residues
MPLNLQKNLPAIELLKKEHIFVMDSLRASEQDIRPLRVVVLNLMPLKITTETDLVRLLSNTPLQVELDFMKIKGHTPKNT
PIEHMQEFYKDFDEMADDFYDGMIVTGAPVEQMPFEEVSYWEEITQIFDWARTHVTSTLYICWAAQAGLYHFYGVPKYDL
PAKMFGVFRHSLREPFVPIFRGFDDEFFVPHSRHTEIRREDIMKVPELTLLSESEESGVYMAMARGGREFFITGHSEYSP
YTLNDEYMRDLGKGLPINKPRNYYRNNDPAQGPVVRWRGHANLLFTNWLNYYVYQETPFRREDIKKLGSL

Sequences:

>Translated_310_residues
MPLNLQKNLPAIELLKKEHIFVMDSLRASEQDIRPLRVVVLNLMPLKITTETDLVRLLSNTPLQVELDFMKIKGHTPKNT
PIEHMQEFYKDFDEMADDFYDGMIVTGAPVEQMPFEEVSYWEEITQIFDWARTHVTSTLYICWAAQAGLYHFYGVPKYDL
PAKMFGVFRHSLREPFVPIFRGFDDEFFVPHSRHTEIRREDIMKVPELTLLSESEESGVYMAMARGGREFFITGHSEYSP
YTLNDEYMRDLGKGLPINKPRNYYRNNDPAQGPVVRWRGHANLLFTNWLNYYVYQETPFRREDIKKLGSL
>Mature_309_residues
PLNLQKNLPAIELLKKEHIFVMDSLRASEQDIRPLRVVVLNLMPLKITTETDLVRLLSNTPLQVELDFMKIKGHTPKNTP
IEHMQEFYKDFDEMADDFYDGMIVTGAPVEQMPFEEVSYWEEITQIFDWARTHVTSTLYICWAAQAGLYHFYGVPKYDLP
AKMFGVFRHSLREPFVPIFRGFDDEFFVPHSRHTEIRREDIMKVPELTLLSESEESGVYMAMARGGREFFITGHSEYSPY
TLNDEYMRDLGKGLPINKPRNYYRNNDPAQGPVVRWRGHANLLFTNWLNYYVYQETPFRREDIKKLGSL

Specific function: Methionine biosynthesis; HTS variant; first step. [C]

COG id: COG1897

COG function: function code E; Homoserine trans-succinylase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HTS family

Homologues:

Organism=Escherichia coli, GI1790443, Length=299, Percent_Identity=46.8227424749164, Blast_Score=308, Evalue=2e-85,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): META_PARD8 (A6LC32)

Other databases:

- EMBL:   CP000140
- RefSeq:   YP_001302868.1
- ProteinModelPortal:   A6LC32
- SMR:   A6LC32
- STRING:   A6LC32
- GeneID:   5306643
- GenomeReviews:   CP000140_GR
- KEGG:   pdi:BDI_1490
- eggNOG:   COG1897
- HOGENOM:   HBG362506
- OMA:   QAGLYYH
- ProtClustDB:   PRK05368
- BioCyc:   PDIS435591:BDI_1490-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00295
- InterPro:   IPR005697
- PANTHER:   PTHR20919
- PIRSF:   PIRSF000450
- ProDom:   PD037892
- TIGRFAMs:   TIGR01001

Pfam domain/function: PF04204 HTS

EC number: =2.3.1.46

Molecular weight: Translated: 36464; Mature: 36333

Theoretical pI: Translated: 5.81; Mature: 5.81

Prosite motif: NA

Important sites: ACT_SITE 142-142

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLNLQKNLPAIELLKKEHIFVMDSLRASEQDIRPLRVVVLNLMPLKITTETDLVRLLSN
CCCCCCCCCCHHHHHHHCCEEEEHHHCCCCCCCHHHHHHHHHHCCEEEECHHHHHHHHCC
TPLQVELDFMKIKGHTPKNTPIEHMQEFYKDFDEMADDFYDGMIVTGAPVEQMPFEEVSY
CCEEEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEECCCHHHCCHHHHHH
WEEITQIFDWARTHVTSTLYICWAAQAGLYHFYGVPKYDLPAKMFGVFRHSLREPFVPIF
HHHHHHHHHHHHHHHHHHEEEEEECCCCCEEECCCCCCCCCHHHHHHHHHHHHCCCHHHH
RGFDDEFFVPHSRHTEIRREDIMKVPELTLLSESEESGVYMAMARGGREFFITGHSEYSP
CCCCCCCCCCCCCCHHHHHHHHHCCCCEEEECCCCCCCEEEEEECCCCEEEEECCCCCCC
YTLNDEYMRDLGKGLPINKPRNYYRNNDPAQGPVVRWRGHANLLFTNWLNYYVYQETPFR
EECCHHHHHHHHCCCCCCCCHHHCCCCCCCCCCEEEECCCCCEEEEEEEEEEEEECCCCC
REDIKKLGSL
HHHHHHHCCC
>Mature Secondary Structure 
PLNLQKNLPAIELLKKEHIFVMDSLRASEQDIRPLRVVVLNLMPLKITTETDLVRLLSN
CCCCCCCCCHHHHHHHCCEEEEHHHCCCCCCCHHHHHHHHHHCCEEEECHHHHHHHHCC
TPLQVELDFMKIKGHTPKNTPIEHMQEFYKDFDEMADDFYDGMIVTGAPVEQMPFEEVSY
CCEEEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEECCCHHHCCHHHHHH
WEEITQIFDWARTHVTSTLYICWAAQAGLYHFYGVPKYDLPAKMFGVFRHSLREPFVPIF
HHHHHHHHHHHHHHHHHHEEEEEECCCCCEEECCCCCCCCCHHHHHHHHHHHHCCCHHHH
RGFDDEFFVPHSRHTEIRREDIMKVPELTLLSESEESGVYMAMARGGREFFITGHSEYSP
CCCCCCCCCCCCCCHHHHHHHHHCCCCEEEECCCCCCCEEEEEECCCCEEEEECCCCCCC
YTLNDEYMRDLGKGLPINKPRNYYRNNDPAQGPVVRWRGHANLLFTNWLNYYVYQETPFR
EECCHHHHHHHHCCCCCCCCHHHCCCCCCCCCCEEEECCCCCEEEEEEEEEEEEECCCCC
REDIKKLGSL
HHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA