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The map label for this gene is lytS [H]

Identifier: 150006091

GI number: 150006091

Start: 4466449

End: 4467477

Strand: Direct

Name: lytS [H]

Synonym: BVU_3600

Alternate gene names: 150006091

Gene position: 4466449-4467477 (Clockwise)

Preceding gene: 150006090

Following gene: 150006092

Centisome position: 86.51

GC content: 38.97

Gene sequence:

>1029_bases
ATGAAATGGAATGTTACATTATATGGCCTTTTATTCTCCGGACTAGGAGCATTTTCCTATCTTCTTCTAGCCAATTATTC
CGATTTGTCACCCCATGTGGCAGATATGCTATTTTCCAAAGGTGCTTTTATCTTCTTCATCACAGCCTTCAATATTCTTG
GCTACTCAACGTTGCGGCTCAGTTCCTGGCTAAACAGTCAATATGCATTGAATATCCGCAAACGTTGGAAAATTATTACC
ATTTATATAGCCGTAACTCTTCTGTTCTTTCTTTTGAATTATAGTTTATTGATTGTCGGAAAACTTCTGGTAGGTTCCTA
CAACATATTTATTTTCCCAAATGGCGGCTGGCGCATCCTCTTTCTGGTATGGTTGGTGGAGTTAGTTATTGTAGGACTAC
TTTTATCTAACCGTTCTATTCAGAACACATTAAAACTGCAACAAGAAGCTGCCGAACTTCAAAAAGAAAATAACACAGCC
CGTTACACCGCCCTGCAAAACCAACTCAATCCACACTTTCTGTTCAACAGTCTTAACACGCTGATTGCAGAAATAGAATA
CAATCCCGCCAATGCAGTCCGCTTCACTAAGCATCTGTCCAGCGTTTACCGCTATGTCCTTCAAAGTCAAGATAAAGTCT
TGGTACCTTTAAGCGAAGAATTGGAATTTATGAGATCCTACCTCTTTCTTCACGAAGTCCGATTAGGAAATTGCATCAGT
TACAAATGTCATCTTCCCGAAGACTATCCTGAAGCCATGCTCCCGCCACTAACTTTGCAACTGCTGGTAGAAAATGTCAT
CAAGCATAATTCCATCACCTCAAACAAGCCTATGCAAATTAATATAGAAATTGAAAATTATTTCCTGACAGTAAGTAACC
CTATCCAACCTAAAAAGAGTAATGACACCTCTTCGGGAGTAGGATTGAATAATCTTTCCAACCGTTGCAAACTACTGCTC
GGTGAAGGAATCATTGTCACTAAAGCAAACAATTTGTTTACCGTAAAAGTACCTTTAGCATATGAATAA

Upstream 100 bases:

>100_bases
CAAGGAACGGAATTTATCCGTACCTATAGTGAATGGAAAATATTAATTTAACACCTCTCCAGTCTATGATTATTCTGTAA
AATATTGTAGCTTTGTTCAC

Downstream 100 bases:

>100_bases
ACTAAACGCAATCATTATAGAAGATGAAGTGCCAGCAGCACGTTTGTTACATTCCATGATTACCCGTCTGCGCCCGCAAT
GGACACTGACCATTATACCG

Product: putative two-component system sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MKWNVTLYGLLFSGLGAFSYLLLANYSDLSPHVADMLFSKGAFIFFITAFNILGYSTLRLSSWLNSQYALNIRKRWKIIT
IYIAVTLLFFLLNYSLLIVGKLLVGSYNIFIFPNGGWRILFLVWLVELVIVGLLLSNRSIQNTLKLQQEAAELQKENNTA
RYTALQNQLNPHFLFNSLNTLIAEIEYNPANAVRFTKHLSSVYRYVLQSQDKVLVPLSEELEFMRSYLFLHEVRLGNCIS
YKCHLPEDYPEAMLPPLTLQLLVENVIKHNSITSNKPMQINIEIENYFLTVSNPIQPKKSNDTSSGVGLNNLSNRCKLLL
GEGIIVTKANNLFTVKVPLAYE

Sequences:

>Translated_342_residues
MKWNVTLYGLLFSGLGAFSYLLLANYSDLSPHVADMLFSKGAFIFFITAFNILGYSTLRLSSWLNSQYALNIRKRWKIIT
IYIAVTLLFFLLNYSLLIVGKLLVGSYNIFIFPNGGWRILFLVWLVELVIVGLLLSNRSIQNTLKLQQEAAELQKENNTA
RYTALQNQLNPHFLFNSLNTLIAEIEYNPANAVRFTKHLSSVYRYVLQSQDKVLVPLSEELEFMRSYLFLHEVRLGNCIS
YKCHLPEDYPEAMLPPLTLQLLVENVIKHNSITSNKPMQINIEIENYFLTVSNPIQPKKSNDTSSGVGLNNLSNRCKLLL
GEGIIVTKANNLFTVKVPLAYE
>Mature_342_residues
MKWNVTLYGLLFSGLGAFSYLLLANYSDLSPHVADMLFSKGAFIFFITAFNILGYSTLRLSSWLNSQYALNIRKRWKIIT
IYIAVTLLFFLLNYSLLIVGKLLVGSYNIFIFPNGGWRILFLVWLVELVIVGLLLSNRSIQNTLKLQQEAAELQKENNTA
RYTALQNQLNPHFLFNSLNTLIAEIEYNPANAVRFTKHLSSVYRYVLQSQDKVLVPLSEELEFMRSYLFLHEVRLGNCIS
YKCHLPEDYPEAMLPPLTLQLLVENVIKHNSITSNKPMQINIEIENYFLTVSNPIQPKKSNDTSSGVGLNNLSNRCKLLL
GEGIIVTKANNLFTVKVPLAYE

Specific function: Member of the two-component regulatory system lytS/lytT that probably regulates genes involved in cell wall metabolism [H]

COG id: COG3275

COG function: function code T; Putative regulator of cell autolysis

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788723, Length=193, Percent_Identity=28.4974093264249, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1788446, Length=176, Percent_Identity=28.9772727272727, Blast_Score=80, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR010559
- InterPro:   IPR005467
- InterPro:   IPR011620 [H]

Pfam domain/function: PF07694 5TM-5TMR_LYT; PF01590 GAF; PF02518 HATPase_c; PF06580 His_kinase [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 39032; Mature: 39032

Theoretical pI: Translated: 9.26; Mature: 9.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKWNVTLYGLLFSGLGAFSYLLLANYSDLSPHVADMLFSKGAFIFFITAFNILGYSTLRL
CEEEEEEHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCEEHEEHHHHHHHHHHHH
SSWLNSQYALNIRKRWKIITIYIAVTLLFFLLNYSLLIVGKLLVGSYNIFIFPNGGWRIL
HHHCCCCEEEEEECCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCHHHH
FLVWLVELVIVGLLLSNRSIQNTLKLQQEAAELQKENNTARYTALQNQLNPHFLFNSLNT
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHH
LIAEIEYNPANAVRFTKHLSSVYRYVLQSQDKVLVPLSEELEFMRSYLFLHEVRLGNCIS
HHEEEECCCCHHHHHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHHHHHCCCEEE
YKCHLPEDYPEAMLPPLTLQLLVENVIKHNSITSNKPMQINIEIENYFLTVSNPIQPKKS
EEECCCCCCCHHHCCHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEEEEEEECCCCCCCCC
NDTSSGVGLNNLSNRCKLLLGEGIIVTKANNLFTVKVPLAYE
CCCCCCCCCCCHHHHHEEEECCCEEEEECCCEEEEEEEEECC
>Mature Secondary Structure
MKWNVTLYGLLFSGLGAFSYLLLANYSDLSPHVADMLFSKGAFIFFITAFNILGYSTLRL
CEEEEEEHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCEEHEEHHHHHHHHHHHH
SSWLNSQYALNIRKRWKIITIYIAVTLLFFLLNYSLLIVGKLLVGSYNIFIFPNGGWRIL
HHHCCCCEEEEEECCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCHHHH
FLVWLVELVIVGLLLSNRSIQNTLKLQQEAAELQKENNTARYTALQNQLNPHFLFNSLNT
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHH
LIAEIEYNPANAVRFTKHLSSVYRYVLQSQDKVLVPLSEELEFMRSYLFLHEVRLGNCIS
HHEEEECCCCHHHHHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHHHHHCCCEEE
YKCHLPEDYPEAMLPPLTLQLLVENVIKHNSITSNKPMQINIEIENYFLTVSNPIQPKKS
EEECCCCCCCHHHCCHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEEEEEEECCCCCCCCC
NDTSSGVGLNNLSNRCKLLLGEGIIVTKANNLFTVKVPLAYE
CCCCCCCCCCCHHHHHEEEECCCEEEEECCCEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]