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The map label for this gene is crp [C]

Identifier: 150006071

GI number: 150006071

Start: 4443344

End: 4444045

Strand: Direct

Name: crp [C]

Synonym: BVU_3580

Alternate gene names: 150006071

Gene position: 4443344-4444045 (Clockwise)

Preceding gene: 150006070

Following gene: 150006072

Centisome position: 86.06

GC content: 37.46

Gene sequence:

>702_bases
ATGGTTAGAAAAGAATTATCAGAAACTGAGATTGCTGAAAGTATACCAGACTTATGGCAACCTTTAACACAGGAACAAAG
AGAGTTCTTGGCTCAGAACTTTACGATACAGAAGTATAAAAAGAATGAGACGATATACTGCGAAGGAGAAACTCCGATGC
ACCTTATGTGTCTTCTTAGTGGAAAAGTAAAAATCTACAAAGAAGGTGTGGGAGGACGTAGCCAGATTATCCGCGTATTA
AAGACGAAAGAATATTTCGCATACCGAGCTTTTTTTGCCGAAGGGAACTTCGTGACAGCTGCTTCCGCTTTCGAGCCTTG
CACTATCTGCCTTATTCCCATGCCGGCCATTATGAAACTGATAAAAGACAACTCTGAATTAGCTTTGTTCTTTATCCGCC
AACTTTCTATAGATTTGGGAATTTCTGATGAAAGAACCGTAAATCTTACGCAAAAACATATTCGTGGACGATTGGCGGAA
TCTCTGTTATTTTTGAAAGATACTTATGGAGTAGAAGAAGATGAATCTACACTAAGCATTTACCTTTCACGAGAAGATTT
GGCAAACTTATCAAATATGACTACTTCGAACGCAATCCGTACGCTTTCTAACTTTGCAACTGAAAAACTGATTACCATCG
ACGGTAGAAAAATTAAAATCATTGATGAAGAGAAACTAAAAAAAATCAGCAAAATAGGATAA

Upstream 100 bases:

>100_bases
ATAAATTAATAATATATCTTTCTTTTTTCTTCTGATTACTTCGTCCTTTTATTTTTTCTTCTTATATTTGTGCTCTATAA
CACGGTTTTATAGCACGTTT

Downstream 100 bases:

>100_bases
AATCTAATATCAATTCATACTTCACACACACAGGCGTCCGTTTTTCCATAACAGACGCCTGTTTTTTCTCTACTTACAAA
ACCTTTTTCAGTACCAGCTG

Product: transcriptional regulator

Products: NA

Alternate protein names: Crp/FNR Family Transcriptional Regulator; Transcriptional Regulator; CRP/FNR Family Transcriptional Regulator; Crp/Fnr Family Transcriptional Regulator; Transcriptional Regulatory Protein; Transcriptional Regulator CAP Family; Crp-Family Transcriptional Regulator; Crp Family Transcriptional Regulator; Fumarate And Nitrate Reduction Regulatory Protein; Response Regulator Receiver; Crp Family Regulatory Protein; DNR Protein; FNR Family Transcriptional Regulator Protein; Transcription Regulator; Global Nitrogen Regulator NtcA

Number of amino acids: Translated: 233; Mature: 233

Protein sequence:

>233_residues
MVRKELSETEIAESIPDLWQPLTQEQREFLAQNFTIQKYKKNETIYCEGETPMHLMCLLSGKVKIYKEGVGGRSQIIRVL
KTKEYFAYRAFFAEGNFVTAASAFEPCTICLIPMPAIMKLIKDNSELALFFIRQLSIDLGISDERTVNLTQKHIRGRLAE
SLLFLKDTYGVEEDESTLSIYLSREDLANLSNMTTSNAIRTLSNFATEKLITIDGRKIKIIDEEKLKKISKIG

Sequences:

>Translated_233_residues
MVRKELSETEIAESIPDLWQPLTQEQREFLAQNFTIQKYKKNETIYCEGETPMHLMCLLSGKVKIYKEGVGGRSQIIRVL
KTKEYFAYRAFFAEGNFVTAASAFEPCTICLIPMPAIMKLIKDNSELALFFIRQLSIDLGISDERTVNLTQKHIRGRLAE
SLLFLKDTYGVEEDESTLSIYLSREDLANLSNMTTSNAIRTLSNFATEKLITIDGRKIKIIDEEKLKKISKIG
>Mature_233_residues
MVRKELSETEIAESIPDLWQPLTQEQREFLAQNFTIQKYKKNETIYCEGETPMHLMCLLSGKVKIYKEGVGGRSQIIRVL
KTKEYFAYRAFFAEGNFVTAASAFEPCTICLIPMPAIMKLIKDNSELALFFIRQLSIDLGISDERTVNLTQKHIRGRLAE
SLLFLKDTYGVEEDESTLSIYLSREDLANLSNMTTSNAIRTLSNFATEKLITIDGRKIKIIDEEKLKKISKIG

Specific function: This Protein Complexes With Cyclic AMP And Binds To Specific DNA Sites Near The Promoter To Regulate The Transcription Of Several Catabolite-Sensitive Operons. The Protein Induces A Severe Bend In The DNA. Acts As A Negative Regulator Of Its Own Synthesi

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 26604; Mature: 26604

Theoretical pI: Translated: 7.29; Mature: 7.29

Prosite motif: PS50042 CNMP_BINDING_3 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVRKELSETEIAESIPDLWQPLTQEQREFLAQNFTIQKYKKNETIYCEGETPMHLMCLLS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCEEEECCCCCEEEEEEEC
GKVKIYKEGVGGRSQIIRVLKTKEYFAYRAFFAEGNFVTAASAFEPCTICLIPMPAIMKL
CCEEEEECCCCCHHHHHHHHHHHHHHHEEEEEECCCEEEECCCCCCEEEEEECHHHHHHH
IKDNSELALFFIRQLSIDLGISDERTVNLTQKHIRGRLAESLLFLKDTYGVEEDESTLSI
HCCCCHHHHHEEHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEE
YLSREDLANLSNMTTSNAIRTLSNFATEKLITIDGRKIKIIDEEKLKKISKIG
EEEHHHHHHHHHCHHHHHHHHHHHHHHCEEEEECCCEEEEECHHHHHHHHCCC
>Mature Secondary Structure
MVRKELSETEIAESIPDLWQPLTQEQREFLAQNFTIQKYKKNETIYCEGETPMHLMCLLS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCEEEECCCCCEEEEEEEC
GKVKIYKEGVGGRSQIIRVLKTKEYFAYRAFFAEGNFVTAASAFEPCTICLIPMPAIMKL
CCEEEEECCCCCHHHHHHHHHHHHHHHEEEEEECCCEEEECCCCCCEEEEEECHHHHHHH
IKDNSELALFFIRQLSIDLGISDERTVNLTQKHIRGRLAESLLFLKDTYGVEEDESTLSI
HCCCCHHHHHEEHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEE
YLSREDLANLSNMTTSNAIRTLSNFATEKLITIDGRKIKIIDEEKLKKISKIG
EEEHHHHHHHHHCHHHHHHHHHHHHHHCEEEEECCCEEEEECHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA