Click here to switch to the map view.

The map label for this gene is dnaC [H]

Identifier: 150005969

GI number: 150005969

Start: 4318180

End: 4319736

Strand: Direct

Name: dnaC [H]

Synonym: BVU_3467

Alternate gene names: 150005969

Gene position: 4318180-4319736 (Clockwise)

Preceding gene: 150005967

Following gene: 150005970

Centisome position: 83.63

GC content: 49.07

Gene sequence:

>1557_bases
ATGGCAGAAACGAGAAAAATGACACGTACTCCCAAAACTTCGAAAGCAAAGCCTGTTGACGAATACGGACATTTACAGCC
CCAGGCACCTGAGCTGGAGGAAGCTGTATTGGGAGCCTTAATGATAGAAAAAGATGCTTACTCATTAGTAAGTGAGATTC
TTCGTCCCGAATCTTTTTATGAACGCCGTCACCAACTTATTTATTCGGCTATTACCTCTTTGGCTTTACGCCAGCAACCA
GTCGATATCTTGACTGTGGCCGAACAATTACGCAGCACCGGTGAACTGGAAGATGCAGGCGGTCCTTTTTACATAACACA
GCTAAGCGGCAAGGTAGCCTCTTCCGCACACATAGAATATCACGCACGTATCATCGCGCAGAAGTTTCTTGCACGCGAAC
TGATTACCTTTACCAGCAACATCCAGACAAAGGCTTTCGACGAAACCCAAGACGTGGACGACCTGATGCAGGAAGCGGAA
GGAAAACTGTTCGAAATCTCGCAGCAGAACATGAAGAAGGATTATACGCAAATCAACCCTGTCATCCAGGAAGCGTATGA
GATGCTTCAAAAAGCGGCGGCACGAACGGACGGGCTGAGTGGTCTGGAAAGCGGTTTCCATGCATTGGACAAAATGACCT
CGGGCTGGCAAAATTCCGACCTGGTGATTATTGCCGCCCGCCCCGCTATGGGTAAAACGGCTTTTGTGCTTTCCATGGCA
AAGAACATGGCGGTAAATGCGAAAATCCCTGTGGCTTTGTTCTCTCTTGAAATGTCCAACGTACAGTTGGTCAACCGTAT
GATTGTCAACGTGTGCGAAATTCCGGGTGAGAAAATCAAGAGTGGTCAGTTGGCTCCGTATGAATGGGGACAACTGGATT
ATAAAATAAAAGAATTATACGATGCTCCGATGTATGTGGATGACACACCATCCTTGTCCGTCTTTGAATTACGCACCAAA
GCACGACGGCTTGTACGCGAGCATGGAGTAAAAATCATTATCATTGACTACCTTCAGTTAATGAATGCCAGCGGAATGTC
ATTCGGTAGCCGTCAGGAAGAGGTCAGTACCATTTCACGTTCACTGAAGGGGTTAGCCAAAGAACTGAACATCCCCATCA
TCGCACTGAGCCAGCTGAACCGTGGTGTGGAAAGTCGTGAGGGTATTGACGGAAAACGCCCCCAGCTCAGTGACCTCCGT
GAATCCGGAGCTATTGAGCAGGATGCCGATATGGTATGCTTTATCCACCGCCCGGAATACTATAAAATCTACTCGGATGA
AAAAGGGAACGACTTGCACGGTATGGCAGAAATCATTATCGCCAAGCACCGTAACGGTGCCGTAGGTGATGTACTGCTGC
GTTTCCGTGGCGAATTCGCCCGCTTCCAGAATCCGGACGATGATGTCATCGTGCCTATGCCGGGTGAGGCACCGGGTATT
ATCCGTTCCAAAATGAACGGTGGCGGCAACAGTGTACCTCCCCCATCTCCTGATGCCGCACCTGCCGACAATAATCCGTT
CGGAGCCCCTATTCCCGAAGGACCTTTACCGTTCTGA

Upstream 100 bases:

>100_bases
TCTGTAGATTCAGGTTCATATTTCTTTTATATTTTTGGGAATGGACGAGTGTCCAACTCAGCAAAAAGTTCTATCTTTGC
CCTACTTTAAACAGACGACA

Downstream 100 bases:

>100_bases
CATTTATTTATCCCTCACAGAATTAACACGGATTATTTCCCTCAAAGAAAAATCTGTGTTAATCTGAGTAATCTGTGATG
GATAAATAACAGGATAAAAG

Product: DNA helicase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 518; Mature: 517

Protein sequence:

>518_residues
MAETRKMTRTPKTSKAKPVDEYGHLQPQAPELEEAVLGALMIEKDAYSLVSEILRPESFYERRHQLIYSAITSLALRQQP
VDILTVAEQLRSTGELEDAGGPFYITQLSGKVASSAHIEYHARIIAQKFLARELITFTSNIQTKAFDETQDVDDLMQEAE
GKLFEISQQNMKKDYTQINPVIQEAYEMLQKAAARTDGLSGLESGFHALDKMTSGWQNSDLVIIAARPAMGKTAFVLSMA
KNMAVNAKIPVALFSLEMSNVQLVNRMIVNVCEIPGEKIKSGQLAPYEWGQLDYKIKELYDAPMYVDDTPSLSVFELRTK
ARRLVREHGVKIIIIDYLQLMNASGMSFGSRQEEVSTISRSLKGLAKELNIPIIALSQLNRGVESREGIDGKRPQLSDLR
ESGAIEQDADMVCFIHRPEYYKIYSDEKGNDLHGMAEIIIAKHRNGAVGDVLLRFRGEFARFQNPDDDVIVPMPGEAPGI
IRSKMNGGGNSVPPPSPDAAPADNNPFGAPIPEGPLPF

Sequences:

>Translated_518_residues
MAETRKMTRTPKTSKAKPVDEYGHLQPQAPELEEAVLGALMIEKDAYSLVSEILRPESFYERRHQLIYSAITSLALRQQP
VDILTVAEQLRSTGELEDAGGPFYITQLSGKVASSAHIEYHARIIAQKFLARELITFTSNIQTKAFDETQDVDDLMQEAE
GKLFEISQQNMKKDYTQINPVIQEAYEMLQKAAARTDGLSGLESGFHALDKMTSGWQNSDLVIIAARPAMGKTAFVLSMA
KNMAVNAKIPVALFSLEMSNVQLVNRMIVNVCEIPGEKIKSGQLAPYEWGQLDYKIKELYDAPMYVDDTPSLSVFELRTK
ARRLVREHGVKIIIIDYLQLMNASGMSFGSRQEEVSTISRSLKGLAKELNIPIIALSQLNRGVESREGIDGKRPQLSDLR
ESGAIEQDADMVCFIHRPEYYKIYSDEKGNDLHGMAEIIIAKHRNGAVGDVLLRFRGEFARFQNPDDDVIVPMPGEAPGI
IRSKMNGGGNSVPPPSPDAAPADNNPFGAPIPEGPLPF
>Mature_517_residues
AETRKMTRTPKTSKAKPVDEYGHLQPQAPELEEAVLGALMIEKDAYSLVSEILRPESFYERRHQLIYSAITSLALRQQPV
DILTVAEQLRSTGELEDAGGPFYITQLSGKVASSAHIEYHARIIAQKFLARELITFTSNIQTKAFDETQDVDDLMQEAEG
KLFEISQQNMKKDYTQINPVIQEAYEMLQKAAARTDGLSGLESGFHALDKMTSGWQNSDLVIIAARPAMGKTAFVLSMAK
NMAVNAKIPVALFSLEMSNVQLVNRMIVNVCEIPGEKIKSGQLAPYEWGQLDYKIKELYDAPMYVDDTPSLSVFELRTKA
RRLVREHGVKIIIIDYLQLMNASGMSFGSRQEEVSTISRSLKGLAKELNIPIIALSQLNRGVESREGIDGKRPQLSDLRE
SGAIEQDADMVCFIHRPEYYKIYSDEKGNDLHGMAEIIIAKHRNGAVGDVLLRFRGEFARFQNPDDDVIVPMPGEAPGII
RSKMNGGGNSVPPPSPDAAPADNNPFGAPIPEGPLPF

Specific function: Participates In Initiation And Elongation During Chromosome Replication; It Exhibits DNA-Dependent ATPase Activity And Contains Distinct Active Sites For ATP Binding, DNA Binding, And Interaction With DNAc Protein, Primase, And Other Prepriming Proteins.

COG id: COG0305

COG function: function code L; Replicative DNA helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SF4 helicase domain [H]

Homologues:

Organism=Escherichia coli, GI1790486, Length=449, Percent_Identity=39.8663697104677, Blast_Score=325, Evalue=3e-90,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR007692
- InterPro:   IPR007694
- InterPro:   IPR007693
- InterPro:   IPR016136 [H]

Pfam domain/function: PF00772 DnaB; PF03796 DnaB_C [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 57456; Mature: 57325

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAETRKMTRTPKTSKAKPVDEYGHLQPQAPELEEAVLGALMIEKDAYSLVSEILRPESFY
CCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
ERRHQLIYSAITSLALRQQPVDILTVAEQLRSTGELEDAGGPFYITQLSGKVASSAHIEY
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCHHCCHHHHH
HARIIAQKFLARELITFTSNIQTKAFDETQDVDDLMQEAEGKLFEISQQNMKKDYTQINP
HHHHHHHHHHHHHHHHHHCCCCHHCCCCCCCHHHHHHHHCCCEEEECHHHHHHHHHHHHH
VIQEAYEMLQKAAARTDGLSGLESGFHALDKMTSGWQNSDLVIIAARPAMGKTAFVLSMA
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHH
KNMAVNAKIPVALFSLEMSNVQLVNRMIVNVCEIPGEKIKSGQLAPYEWGQLDYKIKELY
HCCEECCCCCEEEEEECHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCCHHHHHHC
DAPMYVDDTPSLSVFELRTKARRLVREHGVKIIIIDYLQLMNASGMSFGSRQEEVSTISR
CCCCEECCCCCCHHHHHHHHHHHHHHHCCCEEEEHHHHHHHCCCCCCCCCHHHHHHHHHH
SLKGLAKELNIPIIALSQLNRGVESREGIDGKRPQLSDLRESGAIEQDADMVCFIHRPEY
HHHHHHHHCCCCEEEHHHHHCCCHHHCCCCCCCCCHHHHHHCCCCCCCCCEEEEEECCCE
YKIYSDEKGNDLHGMAEIIIAKHRNGAVGDVLLRFRGEFARFQNPDDDVIVPMPGEAPGI
EEEECCCCCCCHHHHHHHHHEECCCCCHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCH
IRSKMNGGGNSVPPPSPDAAPADNNPFGAPIPEGPLPF
HHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AETRKMTRTPKTSKAKPVDEYGHLQPQAPELEEAVLGALMIEKDAYSLVSEILRPESFY
CCCCCCCCCCCCCCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
ERRHQLIYSAITSLALRQQPVDILTVAEQLRSTGELEDAGGPFYITQLSGKVASSAHIEY
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCHHCCHHHHH
HARIIAQKFLARELITFTSNIQTKAFDETQDVDDLMQEAEGKLFEISQQNMKKDYTQINP
HHHHHHHHHHHHHHHHHHCCCCHHCCCCCCCHHHHHHHHCCCEEEECHHHHHHHHHHHHH
VIQEAYEMLQKAAARTDGLSGLESGFHALDKMTSGWQNSDLVIIAARPAMGKTAFVLSMA
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHH
KNMAVNAKIPVALFSLEMSNVQLVNRMIVNVCEIPGEKIKSGQLAPYEWGQLDYKIKELY
HCCEECCCCCEEEEEECHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCCHHHHHHC
DAPMYVDDTPSLSVFELRTKARRLVREHGVKIIIIDYLQLMNASGMSFGSRQEEVSTISR
CCCCEECCCCCCHHHHHHHHHHHHHHHCCCEEEEHHHHHHHCCCCCCCCCHHHHHHHHHH
SLKGLAKELNIPIIALSQLNRGVESREGIDGKRPQLSDLRESGAIEQDADMVCFIHRPEY
HHHHHHHHCCCCEEEHHHHHCCCHHHCCCCCCCCCHHHHHHCCCCCCCCCEEEEEECCCE
YKIYSDEKGNDLHGMAEIIIAKHRNGAVGDVLLRFRGEFARFQNPDDDVIVPMPGEAPGI
EEEECCCCCCCHHHHHHHHHEECCCCCHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCH
IRSKMNGGGNSVPPPSPDAAPADNNPFGAPIPEGPLPF
HHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 1312531 [H]