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The map label for this gene is dcp [H]

Identifier: 150005941

GI number: 150005941

Start: 4285114

End: 4287219

Strand: Direct

Name: dcp [H]

Synonym: BVU_3439

Alternate gene names: 150005941

Gene position: 4285114-4287219 (Clockwise)

Preceding gene: 150005937

Following gene: 150005942

Centisome position: 82.99

GC content: 44.92

Gene sequence:

>2106_bases
ATGAAACACATTCTTTTGGCAGCCTGTGCGGTTGCCATATTAAGCGGTTGCGGTTCGCAAGGGAAACAGGCAGCCCCTAC
CGAAAATCCATTCCTTTCAGAGTACACAACTCCCTTCCAGGTTCCTCCTTTCGACCAAATCAAGATGGAACATTACAAAC
CCGCCTTTTTGCAGGGCATGGAAGAACAACAGAAAGAGATTGACGCTATAGTAAACAACCCCGAACCCGCCACTTTCCAG
AATACCATTGCAGCACTGGATCAAAGCGGAGCGTTACTTCGTAAAGTCAGCACCGTATTCTACGGACTGAAAAGCGCCAA
TACCAATGATGAAATGGACGCACTGAGCCGTGAACTCTCTCCACTACAATCAAAACACAGCGATGACATCGCCTTAAATG
AAAAACTTTTTGCACGTATTAAAGCTGTCTATGAAAATCCCGGCAATTTGGACAAAGAGCAAAAGAAGTTGTTGGAAGAA
ACCTATAAAGATTTTGTACGTGGAGGTGCCAACCTGGATGCCGACAGTCAAAAAAAACTGCGTGAATTAAATAGTGAGAT
TTCCATGTTACAGCTCACCTTCGGCCAAAATATGCAGAAGGAAACCAATGCTTTCCAATTGATCGTGGACAAAGAAGAAG
ACTTAGCCGGATTACCCCAAAACCTGATTGCCAGTGCTGCCGAAACAGCTAAAGAAGCAGGCATGGAAGGCAAATGGATT
TTCACCCTGCATAATCCCAGCGTCATGCCTTTCCTGCAATATGCCGATAACCGAGACCTGCGTGAAAAGATATTCAAAGG
ATACATTAACAGAGGAAATAACGGAAATGAATACGACAACAAGGAAGTGGTACGCAAACTGCTCAAAGCCCGTCTGGAAA
AAGCCAAGCTGATGGGATATGAAAACTATGCTTCCTTTGCACTGGAAGAACGTATGGCGAAAACACCGGATGCCGTATAT
AAATTATTAGACCAGATTTGGACACCTACTCTGTCCAAAGCCAAAGAAGAACTGGCAGATATCAATGCCGAAATAAAGAA
AGACGGAAAAACCTTCACAGCCGAAGGTTGGGACTGGCGTTATTATGCAGACCGAGCCAAGAAAGCCAAATTCGACTTGG
ATGAAAATCAGGTACGTCCTTATCTGAAACTGGAAAACGTACGTGACGGTGTGTTCTATGTTGCCAACAAACTGTACGGT
ATCACTTTCACCCAGCTGGACAATCTTCCCCTCCCTCATCCCGATGCACAGGCATTCGAATGTAAGGACAAAGACGGTTC
TCATCTAGGTGTACTCTATATGGACTTCTTTCCGCGTGCCAGCAAGAAAGGTGGCGCATGGTGCGGAAGCTATCGTTCAC
AGACCTACAAGGACGGCAAGAAAGTGGCTCCTGTAGTAACCGTGGTATGCAACTTTACCAAACCGGCAGCCGGACAACCC
GCTTTGCTCAGTGCAGATGAAGCGAATACCTTGTTCCACGAATTCGGACACGCTTTACATAATCTTTTCAAAGATGTACA
TTATTATGGTGTGGCTAGTGTTCCGCGTGATTTTGTAGAACTGCCGTCACAGATAGATGAGCATTGGGCTTTTGAACCGG
AGGTATTGAATGTATATGCCAAACATTATCAGACAGGTGAAGTTATTCCTGCCGGACTGGTTGAAAAAATGGACAAGAGT
GGCAAATACGGACAAGGCTTCGCTACGGCTGAATATTTAGCTGCTTCCCTGCTGGATATGGATTATCATGTATTAAAAGA
AATTCCCGATGATATGGACGTTATGCAGTTCGAAGCAGAAACATTAGGTAAGCGCGGATTGCTGAAACAAATTCCGTCAC
GCTATCGCACCACTTATTTCAACCACACCATGGGTGGTGGATATACTGCCGGTTACTATAGTTATATTTGGGCAGAAGTG
CTGGATTGTGACGCATACGAGGCATACAAGGAAACAGGCGATATCTTTAATCAAGAAGTAGCAGGAAAGTTCCGCAAATA
TATCCTCACTCCCGGCTGCATTGACGATGCGATGGACATGTATGTCAATTTCCGTGGCAAAGAACCCGGTATTGATCCCT
TGTTAAAGAACAGAGGACTAAAATAA

Upstream 100 bases:

>100_bases
ACAGACTATGAAAACAAACAAATAGTTCTACGCTTCAAACTTATTGGAATTTGCCTTATTTTACTATCTTTGCATTATCA
CCTATATAAAACAAATTATT

Downstream 100 bases:

>100_bases
CCCTCTAACCCTAAATAGAATTCCTCCCCCTGCAAAAGACAAATGATTGTGACTCTTGCAGTGGGAGGATTCTCATTTTG
TAGTATGATTGCGGATAGTT

Product: peptidyl-dipeptidase

Products: NA

Alternate protein names: Dipeptidyl carboxypeptidase [H]

Number of amino acids: Translated: 701; Mature: 701

Protein sequence:

>701_residues
MKHILLAACAVAILSGCGSQGKQAAPTENPFLSEYTTPFQVPPFDQIKMEHYKPAFLQGMEEQQKEIDAIVNNPEPATFQ
NTIAALDQSGALLRKVSTVFYGLKSANTNDEMDALSRELSPLQSKHSDDIALNEKLFARIKAVYENPGNLDKEQKKLLEE
TYKDFVRGGANLDADSQKKLRELNSEISMLQLTFGQNMQKETNAFQLIVDKEEDLAGLPQNLIASAAETAKEAGMEGKWI
FTLHNPSVMPFLQYADNRDLREKIFKGYINRGNNGNEYDNKEVVRKLLKARLEKAKLMGYENYASFALEERMAKTPDAVY
KLLDQIWTPTLSKAKEELADINAEIKKDGKTFTAEGWDWRYYADRAKKAKFDLDENQVRPYLKLENVRDGVFYVANKLYG
ITFTQLDNLPLPHPDAQAFECKDKDGSHLGVLYMDFFPRASKKGGAWCGSYRSQTYKDGKKVAPVVTVVCNFTKPAAGQP
ALLSADEANTLFHEFGHALHNLFKDVHYYGVASVPRDFVELPSQIDEHWAFEPEVLNVYAKHYQTGEVIPAGLVEKMDKS
GKYGQGFATAEYLAASLLDMDYHVLKEIPDDMDVMQFEAETLGKRGLLKQIPSRYRTTYFNHTMGGGYTAGYYSYIWAEV
LDCDAYEAYKETGDIFNQEVAGKFRKYILTPGCIDDAMDMYVNFRGKEPGIDPLLKNRGLK

Sequences:

>Translated_701_residues
MKHILLAACAVAILSGCGSQGKQAAPTENPFLSEYTTPFQVPPFDQIKMEHYKPAFLQGMEEQQKEIDAIVNNPEPATFQ
NTIAALDQSGALLRKVSTVFYGLKSANTNDEMDALSRELSPLQSKHSDDIALNEKLFARIKAVYENPGNLDKEQKKLLEE
TYKDFVRGGANLDADSQKKLRELNSEISMLQLTFGQNMQKETNAFQLIVDKEEDLAGLPQNLIASAAETAKEAGMEGKWI
FTLHNPSVMPFLQYADNRDLREKIFKGYINRGNNGNEYDNKEVVRKLLKARLEKAKLMGYENYASFALEERMAKTPDAVY
KLLDQIWTPTLSKAKEELADINAEIKKDGKTFTAEGWDWRYYADRAKKAKFDLDENQVRPYLKLENVRDGVFYVANKLYG
ITFTQLDNLPLPHPDAQAFECKDKDGSHLGVLYMDFFPRASKKGGAWCGSYRSQTYKDGKKVAPVVTVVCNFTKPAAGQP
ALLSADEANTLFHEFGHALHNLFKDVHYYGVASVPRDFVELPSQIDEHWAFEPEVLNVYAKHYQTGEVIPAGLVEKMDKS
GKYGQGFATAEYLAASLLDMDYHVLKEIPDDMDVMQFEAETLGKRGLLKQIPSRYRTTYFNHTMGGGYTAGYYSYIWAEV
LDCDAYEAYKETGDIFNQEVAGKFRKYILTPGCIDDAMDMYVNFRGKEPGIDPLLKNRGLK
>Mature_701_residues
MKHILLAACAVAILSGCGSQGKQAAPTENPFLSEYTTPFQVPPFDQIKMEHYKPAFLQGMEEQQKEIDAIVNNPEPATFQ
NTIAALDQSGALLRKVSTVFYGLKSANTNDEMDALSRELSPLQSKHSDDIALNEKLFARIKAVYENPGNLDKEQKKLLEE
TYKDFVRGGANLDADSQKKLRELNSEISMLQLTFGQNMQKETNAFQLIVDKEEDLAGLPQNLIASAAETAKEAGMEGKWI
FTLHNPSVMPFLQYADNRDLREKIFKGYINRGNNGNEYDNKEVVRKLLKARLEKAKLMGYENYASFALEERMAKTPDAVY
KLLDQIWTPTLSKAKEELADINAEIKKDGKTFTAEGWDWRYYADRAKKAKFDLDENQVRPYLKLENVRDGVFYVANKLYG
ITFTQLDNLPLPHPDAQAFECKDKDGSHLGVLYMDFFPRASKKGGAWCGSYRSQTYKDGKKVAPVVTVVCNFTKPAAGQP
ALLSADEANTLFHEFGHALHNLFKDVHYYGVASVPRDFVELPSQIDEHWAFEPEVLNVYAKHYQTGEVIPAGLVEKMDKS
GKYGQGFATAEYLAASLLDMDYHVLKEIPDDMDVMQFEAETLGKRGLLKQIPSRYRTTYFNHTMGGGYTAGYYSYIWAEV
LDCDAYEAYKETGDIFNQEVAGKFRKYILTPGCIDDAMDMYVNFRGKEPGIDPLLKNRGLK

Specific function: Removes dipeptides from the C-termini of N-blocked tripeptides, tetrapeptides and larger peptides [H]

COG id: COG0339

COG function: function code E; Zn-dependent oligopeptidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M3 family [H]

Homologues:

Organism=Homo sapiens, GI4507491, Length=639, Percent_Identity=27.2300469483568, Blast_Score=265, Evalue=1e-70,
Organism=Homo sapiens, GI14149738, Length=640, Percent_Identity=29.375, Blast_Score=239, Evalue=5e-63,
Organism=Homo sapiens, GI156105687, Length=570, Percent_Identity=26.4912280701754, Blast_Score=154, Evalue=4e-37,
Organism=Escherichia coli, GI1787819, Length=680, Percent_Identity=41.6176470588235, Blast_Score=529, Evalue=1e-151,
Organism=Escherichia coli, GI1789913, Length=686, Percent_Identity=32.6530612244898, Blast_Score=386, Evalue=1e-108,
Organism=Caenorhabditis elegans, GI32565901, Length=542, Percent_Identity=19.5571955719557, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI71999758, Length=580, Percent_Identity=19.1379310344828, Blast_Score=74, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6319793, Length=666, Percent_Identity=29.7297297297297, Blast_Score=230, Evalue=5e-61,
Organism=Saccharomyces cerevisiae, GI6322715, Length=711, Percent_Identity=24.0506329113924, Blast_Score=133, Evalue=9e-32,
Organism=Drosophila melanogaster, GI21356111, Length=549, Percent_Identity=21.8579234972678, Blast_Score=147, Evalue=3e-35,
Organism=Drosophila melanogaster, GI20129717, Length=409, Percent_Identity=26.161369193154, Blast_Score=134, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001567 [H]

Pfam domain/function: PF01432 Peptidase_M3 [H]

EC number: =3.4.15.5 [H]

Molecular weight: Translated: 79160; Mature: 79160

Theoretical pI: Translated: 5.49; Mature: 5.49

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHILLAACAVAILSGCGSQGKQAAPTENPFLSEYTTPFQVPPFDQIKMEHYKPAFLQGM
CCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHCCCCCCCCCHHHHHHHHCCCHHHHCH
EEQQKEIDAIVNNPEPATFQNTIAALDQSGALLRKVSTVFYGLKSANTNDEMDALSRELS
HHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
PLQSKHSDDIALNEKLFARIKAVYENPGNLDKEQKKLLEETYKDFVRGGANLDADSQKKL
HHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
RELNSEISMLQLTFGQNMQKETNAFQLIVDKEEDLAGLPQNLIASAAETAKEAGMEGKWI
HHHHHHHHEEEEHHCCCCHHCCCCEEEEEECCHHHHCCCHHHHHHHHHHHHHCCCCCCEE
FTLHNPSVMPFLQYADNRDLREKIFKGYINRGNNGNEYDNKEVVRKLLKARLEKAKLMGY
EEECCCCCCHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCC
ENYASFALEERMAKTPDAVYKLLDQIWTPTLSKAKEELADINAEIKKDGKTFTAEGWDWR
HHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHCCCCEEECCCCCCH
YYADRAKKAKFDLDENQVRPYLKLENVRDGVFYVANKLYGITFTQLDNLPLPHPDAQAFE
HHHHHHHHCCCCCCHHHCCCHHEECCCCCHHHHHHHHHHCEEEHHCCCCCCCCCCCCCEE
CKDKDGSHLGVLYMDFFPRASKKGGAWCGSYRSQTYKDGKKVAPVVTVVCNFTKPAAGQP
CCCCCCCEEEEEEEECCCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHEECCCCCCCCCC
ALLSADEANTLFHEFGHALHNLFKDVHYYGVASVPRDFVELPSQIDEHWAFEPEVLNVYA
CEECCCHHHHHHHHHHHHHHHHHHHHHHHCCHHCCHHHHHHHHHHHHHCCCCHHHHHHHH
KHYQTGEVIPAGLVEKMDKSGKYGQGFATAEYLAASLLDMDYHVLKEIPDDMDVMQFEAE
HHCCCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
TLGKRGLLKQIPSRYRTTYFNHTMGGGYTAGYYSYIWAEVLDCDAYEAYKETGDIFNQEV
HHHHCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
AGKFRKYILTPGCIDDAMDMYVNFRGKEPGIDPLLKNRGLK
HHHHHHHHCCCCCHHHHHHHHEECCCCCCCCCHHHHCCCCC
>Mature Secondary Structure
MKHILLAACAVAILSGCGSQGKQAAPTENPFLSEYTTPFQVPPFDQIKMEHYKPAFLQGM
CCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHCCCCCCCCCHHHHHHHHCCCHHHHCH
EEQQKEIDAIVNNPEPATFQNTIAALDQSGALLRKVSTVFYGLKSANTNDEMDALSRELS
HHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
PLQSKHSDDIALNEKLFARIKAVYENPGNLDKEQKKLLEETYKDFVRGGANLDADSQKKL
HHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
RELNSEISMLQLTFGQNMQKETNAFQLIVDKEEDLAGLPQNLIASAAETAKEAGMEGKWI
HHHHHHHHEEEEHHCCCCHHCCCCEEEEEECCHHHHCCCHHHHHHHHHHHHHCCCCCCEE
FTLHNPSVMPFLQYADNRDLREKIFKGYINRGNNGNEYDNKEVVRKLLKARLEKAKLMGY
EEECCCCCCHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCC
ENYASFALEERMAKTPDAVYKLLDQIWTPTLSKAKEELADINAEIKKDGKTFTAEGWDWR
HHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHCCCCEEECCCCCCH
YYADRAKKAKFDLDENQVRPYLKLENVRDGVFYVANKLYGITFTQLDNLPLPHPDAQAFE
HHHHHHHHCCCCCCHHHCCCHHEECCCCCHHHHHHHHHHCEEEHHCCCCCCCCCCCCCEE
CKDKDGSHLGVLYMDFFPRASKKGGAWCGSYRSQTYKDGKKVAPVVTVVCNFTKPAAGQP
CCCCCCCEEEEEEEECCCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHEECCCCCCCCCC
ALLSADEANTLFHEFGHALHNLFKDVHYYGVASVPRDFVELPSQIDEHWAFEPEVLNVYA
CEECCCHHHHHHHHHHHHHHHHHHHHHHHCCHHCCHHHHHHHHHHHHHCCCCHHHHHHHH
KHYQTGEVIPAGLVEKMDKSGKYGQGFATAEYLAASLLDMDYHVLKEIPDDMDVMQFEAE
HHCCCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
TLGKRGLLKQIPSRYRTTYFNHTMGGGYTAGYYSYIWAEVLDCDAYEAYKETGDIFNQEV
HHHHCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
AGKFRKYILTPGCIDDAMDMYVNFRGKEPGIDPLLKNRGLK
HHHHHHHHCCCCCHHHHHHHHEECCCCCCCCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8226676; 9097039; 9278503 [H]