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The map label for this gene is wecB [H]

Identifier: 150005855

GI number: 150005855

Start: 4185697

End: 4186785

Strand: Direct

Name: wecB [H]

Synonym: BVU_3351

Alternate gene names: 150005855

Gene position: 4185697-4186785 (Clockwise)

Preceding gene: 150005848

Following gene: 150005857

Centisome position: 81.07

GC content: 45.0

Gene sequence:

>1089_bases
ATGAAAGTAACAATTATCGCAGGTGCACGTCCCAATTTCATGAAAATTGCCCCATTAATGCGTGCTATCAAGGCTGCAAA
GGCAGCAGGAAAAAATATCACTGCCCGTCTGGTCTACACAGGTTCGGACGAAGATAAAAGTTTGGAACCTTCTCTGTTTA
CAGACCTGGATATGCCGCGTCCTGATGTATATCTGCATGTAGATAATACAGATTTTTTCCAGCAAATGGCAGGTATATTG
GTAGCTTTCGCCCGCGAACTGGAACAGCATCCTGCACAGGTAGTACTTGTAGTGGATGACCTGACTCCTACTATGGCGTG
CTCTATCGTAGCTAAAAAGAAAGGGATAAAAGTCGCTCATCTAGTGGCCGGAACCCGCTCTTTCGATATGGATATGCCAA
AGGAAGTGAACAGCATGATAACAGATGGCTTGTCCGATTATCTGTTCACGGCCGGAATGGTAGCCAACCGCAATCTGAAT
CAAACAGGAACCGAACAGGCACATGTACATTTTGTAGGAAACATCCTGATTGATACGCTGCGTTATAACCGTACCCGTTT
ACAGCGCCCGGTAGCGTTCTCCATTATGGGACTGAAAGAAAAAGAATACCTCTTGCTAACATTGAACAAGCATTCATTGC
TAAACAAGGACACAACACTGAAAGCCATCTTCCACACTATACTGGAAAAAACAGACAAGCCGATCGTGGCGCCGCTCCAT
ACATATGTAAAAAACAAGCTGTCTGCTTTAGGAATTACTTCCGAAAGGTTATATATATTACCACCGCAACCTTATTTGTC
ATTCGGATATTTAGTGAACCATGCCTGGGGTATCATTACAGATTCGGGCAATGTAGCGGAAGAAGCTACTTTTTTAGGAA
TCCCCTGCATGACATTAAGCACGTATGCAGAACATCCCGAAACAGTGACAATCGGCACAAACCGGCTGGTGGGGGAAAAC
TCTGAAATCCTGGCAGACGCCCTTGACATTCTGAATAAAGGAGAATGGCAGAAGGGACATTTGCCGGAACGCTGGGACGG
ACACGCAGCAGAAAGAATTGTGCAAACATTGCTGGGTGAACATAAATAA

Upstream 100 bases:

>100_bases
TGAACAAATGTTAGCATAATGGTTGTTATTTGTCTGCAAAGTAACGAATAAATTCGATAAGAAAATGTATTTTTGTGTTC
AGAAAATAGCTTAAAATAAG

Downstream 100 bases:

>100_bases
AATGGAGCACCAATAAAAACACGGATGCCGCAGAATTTGATATTCTGCGGCATCCGTGTTTTTATTGGTGCTCCATCGAT
ATCGCTTACACTCTCCTTTC

Product: putative UDP-N-acetylglucosamine 2-epimerase

Products: NA

Alternate protein names: UDP-GlcNAc-2-epimerase [H]

Number of amino acids: Translated: 362; Mature: 362

Protein sequence:

>362_residues
MKVTIIAGARPNFMKIAPLMRAIKAAKAAGKNITARLVYTGSDEDKSLEPSLFTDLDMPRPDVYLHVDNTDFFQQMAGIL
VAFARELEQHPAQVVLVVDDLTPTMACSIVAKKKGIKVAHLVAGTRSFDMDMPKEVNSMITDGLSDYLFTAGMVANRNLN
QTGTEQAHVHFVGNILIDTLRYNRTRLQRPVAFSIMGLKEKEYLLLTLNKHSLLNKDTTLKAIFHTILEKTDKPIVAPLH
TYVKNKLSALGITSERLYILPPQPYLSFGYLVNHAWGIITDSGNVAEEATFLGIPCMTLSTYAEHPETVTIGTNRLVGEN
SEILADALDILNKGEWQKGHLPERWDGHAAERIVQTLLGEHK

Sequences:

>Translated_362_residues
MKVTIIAGARPNFMKIAPLMRAIKAAKAAGKNITARLVYTGSDEDKSLEPSLFTDLDMPRPDVYLHVDNTDFFQQMAGIL
VAFARELEQHPAQVVLVVDDLTPTMACSIVAKKKGIKVAHLVAGTRSFDMDMPKEVNSMITDGLSDYLFTAGMVANRNLN
QTGTEQAHVHFVGNILIDTLRYNRTRLQRPVAFSIMGLKEKEYLLLTLNKHSLLNKDTTLKAIFHTILEKTDKPIVAPLH
TYVKNKLSALGITSERLYILPPQPYLSFGYLVNHAWGIITDSGNVAEEATFLGIPCMTLSTYAEHPETVTIGTNRLVGEN
SEILADALDILNKGEWQKGHLPERWDGHAAERIVQTLLGEHK
>Mature_362_residues
MKVTIIAGARPNFMKIAPLMRAIKAAKAAGKNITARLVYTGSDEDKSLEPSLFTDLDMPRPDVYLHVDNTDFFQQMAGIL
VAFARELEQHPAQVVLVVDDLTPTMACSIVAKKKGIKVAHLVAGTRSFDMDMPKEVNSMITDGLSDYLFTAGMVANRNLN
QTGTEQAHVHFVGNILIDTLRYNRTRLQRPVAFSIMGLKEKEYLLLTLNKHSLLNKDTTLKAIFHTILEKTDKPIVAPLH
TYVKNKLSALGITSERLYILPPQPYLSFGYLVNHAWGIITDSGNVAEEATFLGIPCMTLSTYAEHPETVTIGTNRLVGEN
SEILADALDILNKGEWQKGHLPERWDGHAAERIVQTLLGEHK

Specific function: Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) to produce UDP-N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues [H]

COG id: COG0381

COG function: function code M; UDP-N-acetylglucosamine 2-epimerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-N-acetylglucosamine 2-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI48994967, Length=385, Percent_Identity=29.3506493506493, Blast_Score=114, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003331 [H]

Pfam domain/function: PF02350 Epimerase_2 [H]

EC number: =5.1.3.14 [H]

Molecular weight: Translated: 40201; Mature: 40201

Theoretical pI: Translated: 7.21; Mature: 7.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVTIIAGARPNFMKIAPLMRAIKAAKAAGKNITARLVYTGSDEDKSLEPSLFTDLDMPR
CEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCHHCCCCCCC
PDVYLHVDNTDFFQQMAGILVAFARELEQHPAQVVLVVDDLTPTMACSIVAKKKGIKVAH
CCEEEEECCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHCCCEEEE
LVAGTRSFDMDMPKEVNSMITDGLSDYLFTAGMVANRNLNQTGTEQAHVHFVGNILIDTL
EEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEHHHHHHHHH
RYNRTRLQRPVAFSIMGLKEKEYLLLTLNKHSLLNKDTTLKAIFHTILEKTDKPIVAPLH
HHCHHHHCCCEEEEEECCCCCCEEEEEECCHHHCCCCHHHHHHHHHHHHHCCCCEEHHHH
TYVKNKLSALGITSERLYILPPQPYLSFGYLVNHAWGIITDSGNVAEEATFLGIPCMTLS
HHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHCCEEEEECCCCCHHHHEEECCCHHHHH
TYAEHPETVTIGTNRLVGENSEILADALDILNKGEWQKGHLPERWDGHAAERIVQTLLGE
HHHCCCCEEEECCCEECCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCC
HK
CC
>Mature Secondary Structure
MKVTIIAGARPNFMKIAPLMRAIKAAKAAGKNITARLVYTGSDEDKSLEPSLFTDLDMPR
CEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCHHCCCCCCC
PDVYLHVDNTDFFQQMAGILVAFARELEQHPAQVVLVVDDLTPTMACSIVAKKKGIKVAH
CCEEEEECCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHCCCEEEE
LVAGTRSFDMDMPKEVNSMITDGLSDYLFTAGMVANRNLNQTGTEQAHVHFVGNILIDTL
EEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEHHHHHHHHH
RYNRTRLQRPVAFSIMGLKEKEYLLLTLNKHSLLNKDTTLKAIFHTILEKTDKPIVAPLH
HHCHHHHCCCEEEEEECCCCCCEEEEEECCHHHCCCCHHHHHHHHHHHHHCCCCEEHHHH
TYVKNKLSALGITSERLYILPPQPYLSFGYLVNHAWGIITDSGNVAEEATFLGIPCMTLS
HHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHCCEEEEECCCCCHHHHEEECCCHHHHH
TYAEHPETVTIGTNRLVGENSEILADALDILNKGEWQKGHLPERWDGHAAERIVQTLLGE
HHHCCCCEEEECCCEECCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCC
HK
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]