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The map label for this gene is pyrI

Identifier: 150005842

GI number: 150005842

Start: 4173441

End: 4173908

Strand: Direct

Name: pyrI

Synonym: BVU_3338

Alternate gene names: 150005842

Gene position: 4173441-4173908 (Clockwise)

Preceding gene: 150005841

Following gene: 150005843

Centisome position: 80.83

GC content: 40.38

Gene sequence:

>468_bases
ATGAAGATGAGCGATAATAAACAAGCATTGCAGGTAGCCGCTTTGAAAAACGGCACTGTTATAGACCATATACCTTCCGA
TAAATTGTTTACTGTAGTCGCCCTATTGGGCTTGCAGGATTCTGACTCTAACATAACCATCGGAAACAACTTCGAGAGCA
AAAAATTAGGCAAAAAAGGAATTATAAAAGTGGCCGACCGCTTTTTTACTGATGAGGAAATAAGCCGCCTTTCCGTAGTA
GCCCCGAATGTAAAACTGAACATTATCCGTGACTATGAGGTGGTAGAGAAGAAACAAGTCCTGATGCCTGAGGAATTACG
TGGCATCGTAAAATGCGCCAATCCCAAATGTATCACCAACAATGAGCCAATGACCACCCTGTTTCATGTAATTGACAAAG
AACATGGAATCTTGAAATGTCATTACTGCGAAAAGGAACAAAGTAAAGAAGGTATCAAACTACTGTAA

Upstream 100 bases:

>100_bases
AGGCACAAAACGGACTTTATGCGCGCCAGGCCATCCTTTGTGATGTATTGGGCATAACCTTGAATGATGTTATAGAAGAT
GCAAAAAAGTAAAAACAAAA

Downstream 100 bases:

>100_bases
TGAATATGAAACAAGACTGGAAACCGGGAACTATGATTTACCCTCTTCCGGCCCTACTGGTAAGTTGCGGAAGTACGGAA
GAAGAATATAACATTATCAC

Product: aspartate carbamoyltransferase regulatory subunit

Products: phosphate; N-carbamoyl-L-aspartate [C]

Alternate protein names: NA

Number of amino acids: Translated: 155; Mature: 155

Protein sequence:

>155_residues
MKMSDNKQALQVAALKNGTVIDHIPSDKLFTVVALLGLQDSDSNITIGNNFESKKLGKKGIIKVADRFFTDEEISRLSVV
APNVKLNIIRDYEVVEKKQVLMPEELRGIVKCANPKCITNNEPMTTLFHVIDKEHGILKCHYCEKEQSKEGIKLL

Sequences:

>Translated_155_residues
MKMSDNKQALQVAALKNGTVIDHIPSDKLFTVVALLGLQDSDSNITIGNNFESKKLGKKGIIKVADRFFTDEEISRLSVV
APNVKLNIIRDYEVVEKKQVLMPEELRGIVKCANPKCITNNEPMTTLFHVIDKEHGILKCHYCEKEQSKEGIKLL
>Mature_155_residues
MKMSDNKQALQVAALKNGTVIDHIPSDKLFTVVALLGLQDSDSNITIGNNFESKKLGKKGIIKVADRFFTDEEISRLSVV
APNVKLNIIRDYEVVEKKQVLMPEELRGIVKCANPKCITNNEPMTTLFHVIDKEHGILKCHYCEKEQSKEGIKLL

Specific function: Involved in allosteric regulation of aspartate carbamoyltransferase

COG id: COG1781

COG function: function code F; Aspartate carbamoyltransferase, regulatory subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pyrI family

Homologues:

Organism=Escherichia coli, GI1790692, Length=145, Percent_Identity=42.0689655172414, Blast_Score=120, Evalue=4e-29,

Paralogues:

None

Copy number: 760 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 440 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): PYRI_BACV8 (A6L5K0)

Other databases:

- EMBL:   CP000139
- RefSeq:   YP_001300586.1
- ProteinModelPortal:   A6L5K0
- SMR:   A6L5K0
- STRING:   A6L5K0
- GeneID:   5304299
- GenomeReviews:   CP000139_GR
- KEGG:   bvu:BVU_3338
- NMPDR:   fig|435590.6.peg.3112
- eggNOG:   COG1781
- HOGENOM:   HBG305327
- OMA:   EGTVIDH
- ProtClustDB:   PRK00893
- HAMAP:   MF_00002
- InterPro:   IPR020545
- InterPro:   IPR002801
- InterPro:   IPR020542
- Gene3D:   G3DSA:2.30.30.20
- Gene3D:   G3DSA:3.30.70.140
- ProDom:   PD006194
- TIGRFAMs:   TIGR00240

Pfam domain/function: PF01948 PyrI; PF02748 PyrI_C; SSF54893 Asp_carbamoylTrfase_reg; SSF57825 Asp_transf_reg_C

EC number: NA

Molecular weight: Translated: 17408; Mature: 17408

Theoretical pI: Translated: 8.33; Mature: 8.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKMSDNKQALQVAALKNGTVIDHIPSDKLFTVVALLGLQDSDSNITIGNNFESKKLGKKG
CCCCCCCHHEEEEECCCCEEEECCCCCHHHHHHHHHCCCCCCCEEEECCCCCHHHCCHHH
IIKVADRFFTDEEISRLSVVAPNVKLNIIRDYEVVEKKQVLMPEELRGIVKCANPKCITN
HHHHHHHHCCHHHHCEEEEECCCEEEEEEECCHHHHHHHCCCCHHHHHHHHCCCCEEECC
NEPMTTLFHVIDKEHGILKCHYCEKEQSKEGIKLL
CCCHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCC
>Mature Secondary Structure
MKMSDNKQALQVAALKNGTVIDHIPSDKLFTVVALLGLQDSDSNITIGNNFESKKLGKKG
CCCCCCCHHEEEEECCCCEEEECCCCCHHHHHHHHHCCCCCCCEEEECCCCCHHHCCHHH
IIKVADRFFTDEEISRLSVVAPNVKLNIIRDYEVVEKKQVLMPEELRGIVKCANPKCITN
HHHHHHHHCCHHHHCEEEEECCCEEEEEEECCHHHHHHHCCCCHHHHHHHHCCCCEEECC
NEPMTTLFHVIDKEHGILKCHYCEKEQSKEGIKLL
CCCHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: carbamoyl phosphate; L-aspartate [C]

Specific reaction: carbamoyl phosphate + L-aspartate = phosphate + N-carbamoyl-L-aspartate [C]

General reaction: Transferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA