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The map label for this gene is lysC [H]

Identifier: 150005767

GI number: 150005767

Start: 4091588

End: 4092934

Strand: Direct

Name: lysC [H]

Synonym: BVU_3260

Alternate gene names: 150005767

Gene position: 4091588-4092934 (Clockwise)

Preceding gene: 150005761

Following gene: 150005768

Centisome position: 79.25

GC content: 38.38

Gene sequence:

>1347_bases
ATGAAAGTATATAATTTAGAAAATATTAAATCTGCTGCCGAACTGAAACATCGGACTGAAGTAATTAGCATGAACGAACG
TTCTATTATAGTGCTCGACACTTTTACCGGCATTGCCCAAAAGCTGCAAGCTGTTTCTATTTCTTTATTCCATCTCGATA
TCGAAAAGGTTATGAATCAATTGCAGGATTTCGAGAATGATTGTGGAAATTGGCTGGACAATCTTCTTTCCTCCGAAATG
CAGAAAGCAGAAGCTGCCAAAGAAATAAAAGTACACATCGATCAAATTTCCCGTTTATGTAATGAAAATCCGAACATCAT
TGACGATCATGAGATTATGGCTCACGGAGCAATGATATCCTCTCTTATTCTGTCACATTATTTAGAAGAATGTACGAAAA
AGAACTTCATCTTGAACTCATGTCATTTCATGCGGCTAGGGCTTGATCGGAAACCGGATATAAAGTATGTGAAAAAAAAT
GTAGAAGAACTGATGAAAGCCTGTCCCGATGTCCCCATTCTTATTACCCAAAGCCGTTTGTGTAAAAATGCATATGATGA
AGTGGATTTATTCCCACAAATAGGAAATGAGTATTATGCCACTGTTATCGGGGCTGTATTCCATGCGGATGAAATTATAA
CATCCTTACGTTCTGATGAAATTTGTTTCCAAGGTATGGAACATACTCGGACTCTTACATACGGTGAAGCCGAGAATTTT
ATTGATAGCGGCATTGCATTGCTTCATCCGGAATGTATTCTGCTGGCGCGCACCGTCGGTATGGCCATTGTATTGATAAA
AACACCGGAAGATACATTACGGATATCATCAGAAAAAACAGGAACAAAAGTAAAAGCTGCTGTTTCACGCAGAGGTGTGG
TCTTTGTCAAACTTCGTTCGTTAGGGGTTCTTACTTCTTATCTATTTATTGGAAAAGTATTTGATGTGTTCGAGAAATAT
AAGGTTCCTGTCTATTTAGCGACTTCCTCTAATGTGAGTGTTTCATTGGCTGTGAAATGTAGCAACGACACATTACGCCT
GATATATCGTGAATTACATAAGTATGCGGAAATAGGAATGGAAACAGAAATGTCTGTGGTCAGCGTTATTGGCGATCTAA
ATTGGGAAAAGCATACAGGGTTGGAAGCCAGAATTATAGAAACGCTGAAAGAGATGCCGGTATGCATGATTTCATATGGC
AGCAGCACTCACAATCTTTCAGTGCTGGTACGGGAACAAGATAGAGAAAAGGCATTAATGACACTGTGCAAAGCCTTTCT
AGATATTCCATCAGAAAAATTTGATGTAATAAAACAAACTCAATTACAAGACTCTTTTGTCATGTGA

Upstream 100 bases:

>100_bases
ACTAATAAAGATGAAACTAGTAAGAATATAGCTTTCCAATATGGAAATTTGCCTGTTAAAATGAAAAAGAAACTCGAAAA
GAATAAAATGCAATACAAAA

Downstream 100 bases:

>100_bases
CCTTCTTGAATAAACAGAAGCAACAAATTTGCCCGACAGGTATTTGTTGCTTTTGTTTTTGATTAAATAAAATATTATTT
TATCCTTATAGCGATTTATA

Product: lysine-sensitive aspartokinase III

Products: NA

Alternate protein names: Aspartate kinase III; AKIII; Lysine-sensitive aspartokinase III [H]

Number of amino acids: Translated: 448; Mature: 448

Protein sequence:

>448_residues
MKVYNLENIKSAAELKHRTEVISMNERSIIVLDTFTGIAQKLQAVSISLFHLDIEKVMNQLQDFENDCGNWLDNLLSSEM
QKAEAAKEIKVHIDQISRLCNENPNIIDDHEIMAHGAMISSLILSHYLEECTKKNFILNSCHFMRLGLDRKPDIKYVKKN
VEELMKACPDVPILITQSRLCKNAYDEVDLFPQIGNEYYATVIGAVFHADEIITSLRSDEICFQGMEHTRTLTYGEAENF
IDSGIALLHPECILLARTVGMAIVLIKTPEDTLRISSEKTGTKVKAAVSRRGVVFVKLRSLGVLTSYLFIGKVFDVFEKY
KVPVYLATSSNVSVSLAVKCSNDTLRLIYRELHKYAEIGMETEMSVVSVIGDLNWEKHTGLEARIIETLKEMPVCMISYG
SSTHNLSVLVREQDREKALMTLCKAFLDIPSEKFDVIKQTQLQDSFVM

Sequences:

>Translated_448_residues
MKVYNLENIKSAAELKHRTEVISMNERSIIVLDTFTGIAQKLQAVSISLFHLDIEKVMNQLQDFENDCGNWLDNLLSSEM
QKAEAAKEIKVHIDQISRLCNENPNIIDDHEIMAHGAMISSLILSHYLEECTKKNFILNSCHFMRLGLDRKPDIKYVKKN
VEELMKACPDVPILITQSRLCKNAYDEVDLFPQIGNEYYATVIGAVFHADEIITSLRSDEICFQGMEHTRTLTYGEAENF
IDSGIALLHPECILLARTVGMAIVLIKTPEDTLRISSEKTGTKVKAAVSRRGVVFVKLRSLGVLTSYLFIGKVFDVFEKY
KVPVYLATSSNVSVSLAVKCSNDTLRLIYRELHKYAEIGMETEMSVVSVIGDLNWEKHTGLEARIIETLKEMPVCMISYG
SSTHNLSVLVREQDREKALMTLCKAFLDIPSEKFDVIKQTQLQDSFVM
>Mature_448_residues
MKVYNLENIKSAAELKHRTEVISMNERSIIVLDTFTGIAQKLQAVSISLFHLDIEKVMNQLQDFENDCGNWLDNLLSSEM
QKAEAAKEIKVHIDQISRLCNENPNIIDDHEIMAHGAMISSLILSHYLEECTKKNFILNSCHFMRLGLDRKPDIKYVKKN
VEELMKACPDVPILITQSRLCKNAYDEVDLFPQIGNEYYATVIGAVFHADEIITSLRSDEICFQGMEHTRTLTYGEAENF
IDSGIALLHPECILLARTVGMAIVLIKTPEDTLRISSEKTGTKVKAAVSRRGVVFVKLRSLGVLTSYLFIGKVFDVFEKY
KVPVYLATSSNVSVSLAVKCSNDTLRLIYRELHKYAEIGMETEMSVVSVIGDLNWEKHTGLEARIIETLKEMPVCMISYG
SSTHNLSVLVREQDREKALMTLCKAFLDIPSEKFDVIKQTQLQDSFVM

Specific function: Lysine biosynthesis; first step. [C]

COG id: COG0527

COG function: function code E; Aspartokinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ACT domain [H]

Homologues:

Organism=Escherichia coli, GI1790455, Length=353, Percent_Identity=23.7960339943343, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002912
- InterPro:   IPR001048
- InterPro:   IPR005260
- InterPro:   IPR001341
- InterPro:   IPR018042 [H]

Pfam domain/function: PF00696 AA_kinase; PF01842 ACT [H]

EC number: =2.7.2.4 [H]

Molecular weight: Translated: 50718; Mature: 50718

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVYNLENIKSAAELKHRTEVISMNERSIIVLDTFTGIAQKLQAVSISLFHLDIEKVMNQ
CCCCCCHHHHHHHHHHHHHHHEEECCCEEEEEECHHHHHHHHHHHHHHEEEEEHHHHHHH
LQDFENDCGNWLDNLLSSEMQKAEAAKEIKVHIDQISRLCNENPNIIDDHEIMAHGAMIS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
SLILSHYLEECTKKNFILNSCHFMRLGLDRKPDIKYVKKNVEELMKACPDVPILITQSRL
HHHHHHHHHHHHHCCCCCCCCHHEEECCCCCCCHHHHHHHHHHHHHHCCCCCEEEEHHHH
CKNAYDEVDLFPQIGNEYYATVIGAVFHADEIITSLRSDEICFQGMEHTRTLTYGEAENF
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHCCEEECCCHHHH
IDSGIALLHPECILLARTVGMAIVLIKTPEDTLRISSEKTGTKVKAAVSRRGVVFVKLRS
HHCCHHHHCHHHHHHHHHHCEEEEEEECCCHHEEECCCCCCCHHHHHHHHCCEEEEEEHH
LGVLTSYLFIGKVFDVFEKYKVPVYLATSSNVSVSLAVKCSNDTLRLIYRELHKYAEIGM
HHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEEEEEECCCHHHHHHHHHHHHHHCCC
ETEMSVVSVIGDLNWEKHTGLEARIIETLKEMPVCMISYGSSTHNLSVLVREQDREKALM
CCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCEEEEECCCCCCCEEEEEECCHHHHHHH
TLCKAFLDIPSEKFDVIKQTQLQDSFVM
HHHHHHHCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKVYNLENIKSAAELKHRTEVISMNERSIIVLDTFTGIAQKLQAVSISLFHLDIEKVMNQ
CCCCCCHHHHHHHHHHHHHHHEEECCCEEEEEECHHHHHHHHHHHHHHEEEEEHHHHHHH
LQDFENDCGNWLDNLLSSEMQKAEAAKEIKVHIDQISRLCNENPNIIDDHEIMAHGAMIS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
SLILSHYLEECTKKNFILNSCHFMRLGLDRKPDIKYVKKNVEELMKACPDVPILITQSRL
HHHHHHHHHHHHHCCCCCCCCHHEEECCCCCCCHHHHHHHHHHHHHHCCCCCEEEEHHHH
CKNAYDEVDLFPQIGNEYYATVIGAVFHADEIITSLRSDEICFQGMEHTRTLTYGEAENF
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHCCEEECCCHHHH
IDSGIALLHPECILLARTVGMAIVLIKTPEDTLRISSEKTGTKVKAAVSRRGVVFVKLRS
HHCCHHHHCHHHHHHHHHHCEEEEEEECCCHHEEECCCCCCCHHHHHHHHCCEEEEEEHH
LGVLTSYLFIGKVFDVFEKYKVPVYLATSSNVSVSLAVKCSNDTLRLIYRELHKYAEIGM
HHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEEEEEECCCHHHHHHHHHHHHHHCCC
ETEMSVVSVIGDLNWEKHTGLEARIIETLKEMPVCMISYGSSTHNLSVLVREQDREKALM
CCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCEEEEECCCCCCCEEEEEECCHHHHHHH
TLCKAFLDIPSEKFDVIKQTQLQDSFVM
HHHHHHHCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3003049; 8265357; 9278503; 6312411 [H]