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The map label for this gene is serC

Identifier: 150005748

GI number: 150005748

Start: 4069049

End: 4070119

Strand: Direct

Name: serC

Synonym: BVU_3241

Alternate gene names: 150005748

Gene position: 4069049-4070119 (Clockwise)

Preceding gene: 150005747

Following gene: 150005749

Centisome position: 78.81

GC content: 44.16

Gene sequence:

>1071_bases
ATGAAAAAGCATAATTTCAATGCGGGACCATCTATCTTGCCTCGCGAGGTAATTGAGAAGACAGCACAAGCCGTTCTTGA
TTTTAATGGGTCAGGCCTTTCCATCATGGAAATCAGTCACCGTGCTAAAGATTTTCAGCCTGTAGTAGACGAAGCTGTTG
CTTTGTTTAAGGAACTGTTGAACATCCCGGAAGGGTACTCGGTACTATTCTTGGGGGGTGGAGCCAGCTTGGAATTCTGT
ATGATACCTTTCAACTTCCTCGAAAAAAAAGCTGCTTACCTGAACACAGGCGTATGGGCTAAGAAAGCGATGAAAGAAGC
CAAGGCTTTCGGCGAGGTAGTAGAAGTGGCATCTTCCGCTGAAGCGACCTATACCTATATTCCCAAAGATTATACGGTTC
CCGCCGATGCAGATTATTTCCACGTCACAACGAATAACACAATCTATGGAACAGAACTTCATGAAGATCTGGATTCTCCG
GTTCCTATGATTGCTGATATGTCATCTGATATTTTCTCTCGTCCTATCGACGTTTCTAAATATATTTGTATCTATGGCGG
TGCGCAGAAGAATTTGGCTCCGGCCGGTGTCACTTTCGTTATTGTAAAGAACGATGCTGTGGGCAAGGTATCACGCTATA
TTCCTACTATGCTGAATTATCAGACTCACATTGACGGCGGCTCTATGTTCAACACACCTCCTGTACTTCCTATTTATGCC
GCTTTGCAGACTTTACGCTGGATAAAAGCCAACGGTGGTGTAGCAGAAATGCAGAAACGTGCTAAAGAGAAGGCAGACAT
GCTGTATGCTGAAATAGACCGTAACAAAATGTTCCGTGGCACAGTAACGGATAAAGCCGACCGCTCTTATATGAACATTT
GCTTTGTAATGAATGACGAATACAAAGACCTGGAAGCCGATTTCTTGAAATTTGCCACAGAAAAAGGTATGGTGGGTATT
AAGGGACACCGTTCTGTAGGCGGTTTCCGTGCATCTTGCTACAACGCTATGCCGAAGGAAAGCGTTCAGGCTTTGATTGA
CTGCATGCAGGAATTTGAGAAACTTCATTAA

Upstream 100 bases:

>100_bases
TTCGTAAATTTATTAGCGATTTTTTTGGAAAACTGAAAATAATGTGTAATTTCGCCCAATGTAAGATATAAACAAATTGT
ATAACCAAAACAAACGTCAA

Downstream 100 bases:

>100_bases
TAATTATGTTCACCACAGATTATACGAATTGCACAGATAGGAACAATAAATGGAATCTGTGATAATCCGTGATAATCTGT
GGTGAACCTTTTTAATACAA

Product: phosphoserine aminotransferase

Products: NA

Alternate protein names: Phosphohydroxythreonine aminotransferase; PSAT

Number of amino acids: Translated: 356; Mature: 356

Protein sequence:

>356_residues
MKKHNFNAGPSILPREVIEKTAQAVLDFNGSGLSIMEISHRAKDFQPVVDEAVALFKELLNIPEGYSVLFLGGGASLEFC
MIPFNFLEKKAAYLNTGVWAKKAMKEAKAFGEVVEVASSAEATYTYIPKDYTVPADADYFHVTTNNTIYGTELHEDLDSP
VPMIADMSSDIFSRPIDVSKYICIYGGAQKNLAPAGVTFVIVKNDAVGKVSRYIPTMLNYQTHIDGGSMFNTPPVLPIYA
ALQTLRWIKANGGVAEMQKRAKEKADMLYAEIDRNKMFRGTVTDKADRSYMNICFVMNDEYKDLEADFLKFATEKGMVGI
KGHRSVGGFRASCYNAMPKESVQALIDCMQEFEKLH

Sequences:

>Translated_356_residues
MKKHNFNAGPSILPREVIEKTAQAVLDFNGSGLSIMEISHRAKDFQPVVDEAVALFKELLNIPEGYSVLFLGGGASLEFC
MIPFNFLEKKAAYLNTGVWAKKAMKEAKAFGEVVEVASSAEATYTYIPKDYTVPADADYFHVTTNNTIYGTELHEDLDSP
VPMIADMSSDIFSRPIDVSKYICIYGGAQKNLAPAGVTFVIVKNDAVGKVSRYIPTMLNYQTHIDGGSMFNTPPVLPIYA
ALQTLRWIKANGGVAEMQKRAKEKADMLYAEIDRNKMFRGTVTDKADRSYMNICFVMNDEYKDLEADFLKFATEKGMVGI
KGHRSVGGFRASCYNAMPKESVQALIDCMQEFEKLH
>Mature_356_residues
MKKHNFNAGPSILPREVIEKTAQAVLDFNGSGLSIMEISHRAKDFQPVVDEAVALFKELLNIPEGYSVLFLGGGASLEFC
MIPFNFLEKKAAYLNTGVWAKKAMKEAKAFGEVVEVASSAEATYTYIPKDYTVPADADYFHVTTNNTIYGTELHEDLDSP
VPMIADMSSDIFSRPIDVSKYICIYGGAQKNLAPAGVTFVIVKNDAVGKVSRYIPTMLNYQTHIDGGSMFNTPPVLPIYA
ALQTLRWIKANGGVAEMQKRAKEKADMLYAEIDRNKMFRGTVTDKADRSYMNICFVMNDEYKDLEADFLKFATEKGMVGI
KGHRSVGGFRASCYNAMPKESVQALIDCMQEFEKLH

Specific function: Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine

COG id: COG1932

COG function: function code HE; Phosphoserine aminotransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily

Homologues:

Organism=Homo sapiens, GI17402893, Length=362, Percent_Identity=39.7790055248619, Blast_Score=267, Evalue=1e-71,
Organism=Homo sapiens, GI10863955, Length=360, Percent_Identity=35, Blast_Score=222, Evalue=4e-58,
Organism=Escherichia coli, GI1787136, Length=359, Percent_Identity=44.8467966573816, Blast_Score=299, Evalue=2e-82,
Organism=Caenorhabditis elegans, GI17506897, Length=366, Percent_Identity=39.0710382513661, Blast_Score=271, Evalue=4e-73,
Organism=Saccharomyces cerevisiae, GI6324758, Length=385, Percent_Identity=34.8051948051948, Blast_Score=214, Evalue=2e-56,
Organism=Drosophila melanogaster, GI21356589, Length=358, Percent_Identity=40.5027932960894, Blast_Score=270, Evalue=9e-73,

Paralogues:

None

Copy number: 2500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): SERC_BACV8 (A6L5A6)

Other databases:

- EMBL:   CP000139
- RefSeq:   YP_001300492.1
- ProteinModelPortal:   A6L5A6
- SMR:   A6L5A6
- STRING:   A6L5A6
- GeneID:   5304202
- GenomeReviews:   CP000139_GR
- KEGG:   bvu:BVU_3241
- NMPDR:   fig|435590.6.peg.3021
- eggNOG:   COG1932
- HOGENOM:   HBG289982
- OMA:   TFAWYLA
- ProtClustDB:   PRK05355
- GO:   GO:0005737
- HAMAP:   MF_00160
- InterPro:   IPR000192
- InterPro:   IPR022278
- InterPro:   IPR003248
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- Gene3D:   G3DSA:3.40.640.10
- Gene3D:   G3DSA:3.90.1150.10
- PIRSF:   PIRSF000525
- TIGRFAMs:   TIGR01364

Pfam domain/function: PF00266 Aminotran_5; SSF53383 PyrdxlP-dep_Trfase_major

EC number: =2.6.1.52

Molecular weight: Translated: 39556; Mature: 39556

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: BINDING 41-41 BINDING 99-99 BINDING 147-147 BINDING 166-166 BINDING 189-189

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKHNFNAGPSILPREVIEKTAQAVLDFNGSGLSIMEISHRAKDFQPVVDEAVALFKELL
CCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHCCHHHHHHHHHHHHHHH
NIPEGYSVLFLGGGASLEFCMIPFNFLEKKAAYLNTGVWAKKAMKEAKAFGEVVEVASSA
CCCCCCEEEEEECCCCEEEEEECHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCC
EATYTYIPKDYTVPADADYFHVTTNNTIYGTELHEDLDSPVPMIADMSSDIFSRPIDVSK
CCEEEECCCCCCCCCCCCEEEEECCCEEEECHHHHHHCCCCCHHHHCCHHHHCCCCCCCE
YICIYGGAQKNLAPAGVTFVIVKNDAVGKVSRYIPTMLNYQTHIDGGSMFNTPPVLPIYA
EEEEECCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHCCEEECCCCCCCCCCCCHHHHH
ALQTLRWIKANGGVAEMQKRAKEKADMLYAEIDRNKMFRGTVTDKADRSYMNICFVMNDE
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCEEEEEEEECCC
YKDLEADFLKFATEKGMVGIKGHRSVGGFRASCYNAMPKESVQALIDCMQEFEKLH
CCHHHHHHHHHHHHCCCEEECCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKKHNFNAGPSILPREVIEKTAQAVLDFNGSGLSIMEISHRAKDFQPVVDEAVALFKELL
CCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHCCHHHHHHHHHHHHHHH
NIPEGYSVLFLGGGASLEFCMIPFNFLEKKAAYLNTGVWAKKAMKEAKAFGEVVEVASSA
CCCCCCEEEEEECCCCEEEEEECHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCC
EATYTYIPKDYTVPADADYFHVTTNNTIYGTELHEDLDSPVPMIADMSSDIFSRPIDVSK
CCEEEECCCCCCCCCCCCEEEEECCCEEEECHHHHHHCCCCCHHHHCCHHHHCCCCCCCE
YICIYGGAQKNLAPAGVTFVIVKNDAVGKVSRYIPTMLNYQTHIDGGSMFNTPPVLPIYA
EEEEECCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHCCEEECCCCCCCCCCCCHHHHH
ALQTLRWIKANGGVAEMQKRAKEKADMLYAEIDRNKMFRGTVTDKADRSYMNICFVMNDE
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCEEEEEEEECCC
YKDLEADFLKFATEKGMVGIKGHRSVGGFRASCYNAMPKESVQALIDCMQEFEKLH
CCHHHHHHHHHHHHCCCEEECCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA