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The map label for this gene is zraR [H]

Identifier: 150005686

GI number: 150005686

Start: 4002300

End: 4003667

Strand: Direct

Name: zraR [H]

Synonym: BVU_3176

Alternate gene names: 150005686

Gene position: 4002300-4003667 (Clockwise)

Preceding gene: 150005677

Following gene: 150005687

Centisome position: 77.52

GC content: 41.81

Gene sequence:

>1368_bases
ATGAATGCAAAAGGAAAAATATTGATTATAGATGATAATGAGGACGTGCTTTTTGCACTAAACCTTTTATTGGATCCCTA
CGTGGAAAAAATAAAAGTTACTACTCAACCGACTCGTATTGAGCATTTCATGACTACTTTTCAACCTGATGTTATTCTGC
TTGATATGAATTTTCGTCGGGATGCTATCAGCGGGCAGGAAGGATTCGATTGTCTAGAGCAGATATTAAAGTTAGATCCG
CAGGCTATTGTCTTGTTTATGACTGCTTATGCGGATACAGATAAAGCAGTACGGGCCATTAAGGCTGGAGCTATTGACTT
TATTCCCAAACCTTGGGAAAAAGAAAAACTACTTGCTACGCTTTCATCGGCTATCAAACTTCGTGATTCTCGTAAAGAGG
TCAGGCAACTGAAAGAACAAGTTGTAGCATTGAGCGCGCAGGATGAAGAGATGCCTCAAATGATAGGTCACTCAGTGCCT
ATGCGAGAGGTTTTTGATACTATTCGGAAATTATCGGATACTGATGCTAATATTTTGATATTGGGTGAAAATGGAACCGG
TAAAGATTTGGTGGCCCGTTCTCTACGTTATTTTTCTCCTCGTCGTGAATGTCCTTTTATAACGATTGACTTGGGGAGCA
TACCTGAATCATTATTCGAAAGTGAATTGTTCGGCTATGAAAAAGGGGCTTTTACAGATGCCCGCAAAGCAAAGGCGGGA
CGTATGGAGGTGGCATCAGGAGGAACGCTTTTTTTGGATGAAATAGGGAATTTGTCATTACCTATGCAGGCCAAATTACT
AACAGCCATAGAAAAACGGCAGATTTCACGTTTGGGAGCAACGGATATAATTCCTATTGATGTTCGGTTGATAAGCGCAA
CGAATGTAAATATCCGAGAATTGGTGGAGGAGGGTAATTTCCGTCAAGACCTATTGTATCGTATCAATACGATTGAGATT
ACTATTCCTCCATTGCGGGAAAGGGGAGAGGATGTTCTCTTACTGGCTGATTATTTCTTACAACGGTATACTCATAAATA
TAAGAAAGAGATAAACGGACTGAGCCGCGAAGCCAAGCAGAAACTCATGCGTTACCATTGGCCGGGTAATGTCCGCGAAT
TGCAGCATGCCATAGAACGGGCAATTATTCTTTCGGACTCGCCATTGTTAAAGCCTGCAAATTTCATGTTGCAGCCACAA
CCCGAGAAGAGGGTGAATACGGATGAGATACTGAACTTGGAACAATTAGAACGCAATGCCATAGAACGTGCTATGAAACG
CAGCGAAGGGAACTTGAGTCGTGCAGCGGAATATTTGGGGATTACCCGTTACGCTCTTTATCGGAAACTTGAAAAATTAG
GGTTATGA

Upstream 100 bases:

>100_bases
CGTATCCGCACAGACAACACATTAAAAAAAACAATATCTTTGCAAAAAAGCGGATAGAAAATCTTTTATTCGTATAACAA
GATATATTGAGGATAAAATA

Downstream 100 bases:

>100_bases
GTCGTTTACAAACTTTACGGATGATAGCTTGTATGTTATTAATGGGGGTAGTAGCTATAGCTGCATATCTCTTTTATCAA
CATTCGCTCTATTTTTGCTT

Product: putative two-component system response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 455; Mature: 455

Protein sequence:

>455_residues
MNAKGKILIIDDNEDVLFALNLLLDPYVEKIKVTTQPTRIEHFMTTFQPDVILLDMNFRRDAISGQEGFDCLEQILKLDP
QAIVLFMTAYADTDKAVRAIKAGAIDFIPKPWEKEKLLATLSSAIKLRDSRKEVRQLKEQVVALSAQDEEMPQMIGHSVP
MREVFDTIRKLSDTDANILILGENGTGKDLVARSLRYFSPRRECPFITIDLGSIPESLFESELFGYEKGAFTDARKAKAG
RMEVASGGTLFLDEIGNLSLPMQAKLLTAIEKRQISRLGATDIIPIDVRLISATNVNIRELVEEGNFRQDLLYRINTIEI
TIPPLRERGEDVLLLADYFLQRYTHKYKKEINGLSREAKQKLMRYHWPGNVRELQHAIERAIILSDSPLLKPANFMLQPQ
PEKRVNTDEILNLEQLERNAIERAMKRSEGNLSRAAEYLGITRYALYRKLEKLGL

Sequences:

>Translated_455_residues
MNAKGKILIIDDNEDVLFALNLLLDPYVEKIKVTTQPTRIEHFMTTFQPDVILLDMNFRRDAISGQEGFDCLEQILKLDP
QAIVLFMTAYADTDKAVRAIKAGAIDFIPKPWEKEKLLATLSSAIKLRDSRKEVRQLKEQVVALSAQDEEMPQMIGHSVP
MREVFDTIRKLSDTDANILILGENGTGKDLVARSLRYFSPRRECPFITIDLGSIPESLFESELFGYEKGAFTDARKAKAG
RMEVASGGTLFLDEIGNLSLPMQAKLLTAIEKRQISRLGATDIIPIDVRLISATNVNIRELVEEGNFRQDLLYRINTIEI
TIPPLRERGEDVLLLADYFLQRYTHKYKKEINGLSREAKQKLMRYHWPGNVRELQHAIERAIILSDSPLLKPANFMLQPQ
PEKRVNTDEILNLEQLERNAIERAMKRSEGNLSRAAEYLGITRYALYRKLEKLGL
>Mature_455_residues
MNAKGKILIIDDNEDVLFALNLLLDPYVEKIKVTTQPTRIEHFMTTFQPDVILLDMNFRRDAISGQEGFDCLEQILKLDP
QAIVLFMTAYADTDKAVRAIKAGAIDFIPKPWEKEKLLATLSSAIKLRDSRKEVRQLKEQVVALSAQDEEMPQMIGHSVP
MREVFDTIRKLSDTDANILILGENGTGKDLVARSLRYFSPRRECPFITIDLGSIPESLFESELFGYEKGAFTDARKAKAG
RMEVASGGTLFLDEIGNLSLPMQAKLLTAIEKRQISRLGATDIIPIDVRLISATNVNIRELVEEGNFRQDLLYRINTIEI
TIPPLRERGEDVLLLADYFLQRYTHKYKKEINGLSREAKQKLMRYHWPGNVRELQHAIERAIILSDSPLLKPANFMLQPQ
PEKRVNTDEILNLEQLERNAIERAMKRSEGNLSRAAEYLGITRYALYRKLEKLGL

Specific function: Member of the two-component regulatory system zraS/zraR. When activated by zraS it acts in conjunction with sigma-54 to regulate the expression of zraP. Positively autoregulates the expression of the zraSR operon [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=467, Percent_Identity=36.830835117773, Blast_Score=304, Evalue=7e-84,
Organism=Escherichia coli, GI1790437, Length=450, Percent_Identity=37.5555555555556, Blast_Score=295, Evalue=6e-81,
Organism=Escherichia coli, GI1790299, Length=479, Percent_Identity=34.8643006263048, Blast_Score=275, Evalue=5e-75,
Organism=Escherichia coli, GI87082117, Length=341, Percent_Identity=38.7096774193548, Blast_Score=244, Evalue=8e-66,
Organism=Escherichia coli, GI1788905, Length=425, Percent_Identity=33.6470588235294, Blast_Score=243, Evalue=2e-65,
Organism=Escherichia coli, GI1789233, Length=330, Percent_Identity=40, Blast_Score=236, Evalue=2e-63,
Organism=Escherichia coli, GI87082152, Length=320, Percent_Identity=40, Blast_Score=226, Evalue=3e-60,
Organism=Escherichia coli, GI1789087, Length=336, Percent_Identity=37.202380952381, Blast_Score=224, Evalue=1e-59,
Organism=Escherichia coli, GI1786524, Length=320, Percent_Identity=39.375, Blast_Score=221, Evalue=5e-59,
Organism=Escherichia coli, GI87081872, Length=318, Percent_Identity=38.0503144654088, Blast_Score=212, Evalue=4e-56,
Organism=Escherichia coli, GI1787583, Length=344, Percent_Identity=34.8837209302326, Blast_Score=189, Evalue=3e-49,
Organism=Escherichia coli, GI87081858, Length=341, Percent_Identity=29.0322580645161, Blast_Score=141, Evalue=1e-34,
Organism=Escherichia coli, GI1789828, Length=221, Percent_Identity=35.2941176470588, Blast_Score=127, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 51903; Mature: 51903

Theoretical pI: Translated: 6.71; Mature: 6.71

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAKGKILIIDDNEDVLFALNLLLDPYVEKIKVTTQPTRIEHFMTTFQPDVILLDMNFRR
CCCCCCEEEEECCCCHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHCCCCEEEEECCCCC
DAISGQEGFDCLEQILKLDPQAIVLFMTAYADTDKAVRAIKAGAIDFIPKPWEKEKLLAT
CCCCCCCHHHHHHHHHHCCCHHEEEEEEHHCCHHHHHHHHHCCCCCCCCCCCCHHHHHHH
LSSAIKLRDSRKEVRQLKEQVVALSAQDEEMPQMIGHSVPMREVFDTIRKLSDTDANILI
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCHHHHHHHHHHHCCCCCCEEE
LGENGTGKDLVARSLRYFSPRRECPFITIDLGSIPESLFESELFGYEKGAFTDARKAKAG
ECCCCCCHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHCCCCCCCCCHHHHHCCC
RMEVASGGTLFLDEIGNLSLPMQAKLLTAIEKRQISRLGATDIIPIDVRLISATNVNIRE
CEEECCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEECCCHHHH
LVEEGNFRQDLLYRINTIEITIPPLRERGEDVLLLADYFLQRYTHKYKKEINGLSREAKQ
HHHCCCCHHHHHEEEEEEEEEECCHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHH
KLMRYHWPGNVRELQHAIERAIILSDSPLLKPANFMLQPQPEKRVNTDEILNLEQLERNA
HHHHHCCCCCHHHHHHHHHHEEEECCCCCCCCCCCCCCCCCCCCCCHHHHCCHHHHHHHH
IERAMKRSEGNLSRAAEYLGITRYALYRKLEKLGL
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNAKGKILIIDDNEDVLFALNLLLDPYVEKIKVTTQPTRIEHFMTTFQPDVILLDMNFRR
CCCCCCEEEEECCCCHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHCCCCEEEEECCCCC
DAISGQEGFDCLEQILKLDPQAIVLFMTAYADTDKAVRAIKAGAIDFIPKPWEKEKLLAT
CCCCCCCHHHHHHHHHHCCCHHEEEEEEHHCCHHHHHHHHHCCCCCCCCCCCCHHHHHHH
LSSAIKLRDSRKEVRQLKEQVVALSAQDEEMPQMIGHSVPMREVFDTIRKLSDTDANILI
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCHHHHHHHHHHHCCCCCCEEE
LGENGTGKDLVARSLRYFSPRRECPFITIDLGSIPESLFESELFGYEKGAFTDARKAKAG
ECCCCCCHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHCCCCCCCCCHHHHHCCC
RMEVASGGTLFLDEIGNLSLPMQAKLLTAIEKRQISRLGATDIIPIDVRLISATNVNIRE
CEEECCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEECCCHHHH
LVEEGNFRQDLLYRINTIEITIPPLRERGEDVLLLADYFLQRYTHKYKKEINGLSREAKQ
HHHCCCCHHHHHEEEEEEEEEECCHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHH
KLMRYHWPGNVRELQHAIERAIILSDSPLLKPANFMLQPQPEKRVNTDEILNLEQLERNA
HHHHHCCCCCHHHHHHHHHHEEEECCCCCCCCCCCCCCCCCCCCCCHHHHCCHHHHHHHH
IERAMKRSEGNLSRAAEYLGITRYALYRKLEKLGL
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11243806 [H]