Click here to switch to the map view.

The map label for this gene is ycbL [H]

Identifier: 150005536

GI number: 150005536

Start: 3826997

End: 3827635

Strand: Reverse

Name: ycbL [H]

Synonym: BVU_3020

Alternate gene names: 150005536

Gene position: 3827635-3826997 (Counterclockwise)

Preceding gene: 150005537

Following gene: 150005535

Centisome position: 74.13

GC content: 44.29

Gene sequence:

>639_bases
ATGAAAATAAAGAAATTTGAATTCAATATGTTTCCGGTAAACTGCTACGTGCTATCGGACGAAACAAAGGAAGCCGTCAT
TATTGATGCCGGTTGCTTTTATGAAGAAGAAAAGCAAGCCTTAAAAAGATATATTGACAGCAATAGCCTGACAGTGAAAC
ATTTGTTGAATACGCACCTCCATCTGGACCATATTTTCGGCAACCCATTCCTGTTGCAAGAATACGGGCTAAAAGCCGAA
GCAAATCAAGCGGATGAATTTTGGCTGGAACAAGCACCGGCACAATCACGTATGTTTGGTTTCCAATTGCCCGAAGCACC
CGTGCCATTAGGAAAATATATCTTTGATGGAGATATCATTACTTTCGGCAATACCCAACTGGAAGCTATCCATGTACCGG
GTCATTCGCCGGGAAGCATTGTTTTTTACTGCAAAGAAGCCCACTGTATCTTCAGCGGTGATGTATTGTTCCAAGGAAGT
ATAGGACGTGCAGACCTTACAGGAGGTAACTTCGACGAACTTCGCGAGCATATATGCAGTCGTTTGTTTGTACTCCCCCC
CGACACGGTAGTCTATCCCGGTCATGGAGACCCGACCACTGTGGGAGCAGAAAAAGCGAACAACCCTTTTTTCCGATAA

Upstream 100 bases:

>100_bases
TGCTTTATGATCTGAAAAATGAATTCACGGAAGATTTTTTTAAAACCAAGAAAGTGGTTTATGTAACCATCAGCGGTTTA
TAATTATAGATAAAAAAAAC

Downstream 100 bases:

>100_bases
GATAAAACTTAAAATTCAACTTATATACTACTACCATGAAAACAGATTTATTAGCAGACCGACATATCGGTATACAGGAA
GAAGACCTTCCCGTTATGTT

Product: putative metallo-beta-lactamase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 212; Mature: 212

Protein sequence:

>212_residues
MKIKKFEFNMFPVNCYVLSDETKEAVIIDAGCFYEEEKQALKRYIDSNSLTVKHLLNTHLHLDHIFGNPFLLQEYGLKAE
ANQADEFWLEQAPAQSRMFGFQLPEAPVPLGKYIFDGDIITFGNTQLEAIHVPGHSPGSIVFYCKEAHCIFSGDVLFQGS
IGRADLTGGNFDELREHICSRLFVLPPDTVVYPGHGDPTTVGAEKANNPFFR

Sequences:

>Translated_212_residues
MKIKKFEFNMFPVNCYVLSDETKEAVIIDAGCFYEEEKQALKRYIDSNSLTVKHLLNTHLHLDHIFGNPFLLQEYGLKAE
ANQADEFWLEQAPAQSRMFGFQLPEAPVPLGKYIFDGDIITFGNTQLEAIHVPGHSPGSIVFYCKEAHCIFSGDVLFQGS
IGRADLTGGNFDELREHICSRLFVLPPDTVVYPGHGDPTTVGAEKANNPFFR
>Mature_212_residues
MKIKKFEFNMFPVNCYVLSDETKEAVIIDAGCFYEEEKQALKRYIDSNSLTVKHLLNTHLHLDHIFGNPFLLQEYGLKAE
ANQADEFWLEQAPAQSRMFGFQLPEAPVPLGKYIFDGDIITFGNTQLEAIHVPGHSPGSIVFYCKEAHCIFSGDVLFQGS
IGRADLTGGNFDELREHICSRLFVLPPDTVVYPGHGDPTTVGAEKANNPFFR

Specific function: Unknown

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family [H]

Homologues:

Organism=Homo sapiens, GI41327741, Length=210, Percent_Identity=31.4285714285714, Blast_Score=80, Evalue=1e-15,
Organism=Escherichia coli, GI1787158, Length=214, Percent_Identity=35.981308411215, Blast_Score=149, Evalue=9e-38,
Organism=Caenorhabditis elegans, GI17538952, Length=193, Percent_Identity=32.1243523316062, Blast_Score=74, Evalue=5e-14,
Organism=Drosophila melanogaster, GI221330176, Length=199, Percent_Identity=27.6381909547739, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI21356335, Length=258, Percent_Identity=24.4186046511628, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24667703, Length=258, Percent_Identity=24.4186046511628, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24667711, Length=237, Percent_Identity=24.8945147679325, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279 [H]

Pfam domain/function: PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 23831; Mature: 23831

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIKKFEFNMFPVNCYVLSDETKEAVIIDAGCFYEEEKQALKRYIDSNSLTVKHLLNTHL
CCEEEEEEEEEEEEEEEECCCCCCEEEEECCCCCHHHHHHHHHHHCCCCEEHHHHHHCCE
HLDHIFGNPFLLQEYGLKAEANQADEFWLEQAPAQSRMFGFQLPEAPVPLGKYIFDGDII
EEEECCCCEEEEECCCCCCCCCCCHHHHHHCCCCCCCEEEEECCCCCCCCCCEEECCCEE
TFGNTQLEAIHVPGHSPGSIVFYCKEAHCIFSGDVLFQGSIGRADLTGGNFDELREHICS
EECCCEEEEEECCCCCCCCEEEEEECCEEEEECCEEEECCCCCEECCCCCHHHHHHHHHH
RLFVLPPDTVVYPGHGDPTTVGAEKANNPFFR
CEEEECCCCEEECCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKIKKFEFNMFPVNCYVLSDETKEAVIIDAGCFYEEEKQALKRYIDSNSLTVKHLLNTHL
CCEEEEEEEEEEEEEEEECCCCCCEEEEECCCCCHHHHHHHHHHHCCCCEEHHHHHHCCE
HLDHIFGNPFLLQEYGLKAEANQADEFWLEQAPAQSRMFGFQLPEAPVPLGKYIFDGDII
EEEECCCCEEEEECCCCCCCCCCCHHHHHHCCCCCCCEEEEECCCCCCCCCCEEECCCEE
TFGNTQLEAIHVPGHSPGSIVFYCKEAHCIFSGDVLFQGSIGRADLTGGNFDELREHICS
EECCCEEEEEECCCCCCCCEEEEEECCEEEEECCEEEECCCCCEECCCCCHHHHHHHHHH
RLFVLPPDTVVYPGHGDPTTVGAEKANNPFFR
CEEEECCCCEEECCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]