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The map label for this gene is sglT [H]

Identifier: 150005446

GI number: 150005446

Start: 3718343

End: 3719914

Strand: Reverse

Name: sglT [H]

Synonym: BVU_2929

Alternate gene names: 150005446

Gene position: 3719914-3718343 (Counterclockwise)

Preceding gene: 150005447

Following gene: 150005443

Centisome position: 72.05

GC content: 50.0

Gene sequence:

>1572_bases
ATGCACGCTAATTATTTAGATACGTTAGATTGGGGCATTCTTATTGCCTACTTTCTGATTCTTATAGGCATCGGTATATG
GGCCAGTCTGAAACGCAAAAAAGGCAGCAGCCTTTTTCTCGCCGAGCGTTCCCTGAAGTGGCATCACATCGGTTTCTCCA
TGTGGGGAACCAATGTGGGCCCCTCCATGCTGATAGCCTCAGCCAGTGCCGGATTCACCACCGGCATCGTTTCGGGCAAT
TATGCCTGGTATGCGTTTGTTTTCATCTGCTTGCTGGCTTTTGTCTTTGCCCCCCGTTATTTGGGAGCGCGTATCACCAC
CTTGCCGGAGTTCATGGGGCGGCGTTTCGGACAGTCCACCCGCAACATTCTTGCCTGGTACACCATTGTGACGATCCTTA
TCTCGTGGCTTGCCCTGACCTTATTCGCCGGAGGTATCCTTATCCGTCAGGTTTTCGATATTCCCATGTGGCAATCGGCA
TTGATCCTGCTCGTTATCTCCGCATTCTTCACCATGGCCGGAGGGCTGAAAGCGGTAGCCTATACCAATGTATTCCAGAT
GCTTCTGCTTATTTTCGTATCGGCCACGCTTACTATAGCAGGGCTTTACAAGGTGGGTGGAGTCAGCGCATTGGCCGAAG
CGGTTCCGGCCGATTACTGGAACCTGTTCCGCCCGAATGACGATCCTGCCTTCCCGTGGCTGCCCATCATTCTGGGTTAT
CCCATCATGGGAGTCTGGTTCTGGTGCACAGACCAATCCATGGTACAGCCTGTATTGGCTGCCAAGAATCTGAAAGAAGG
CCAAATGGGTGCCAACTTCACCGGCTGGTTGAAGATACTGGATGTTCCTCTCTATATCCTTCCGGGTATCATCTGTCTGG
CACTCTACCCGGGCTTGAAGAACCCCGATGAGGCCTACATGACTATGGTCACTAACTTATTTCCTGTAGGCATGGTGGGA
TTAGTACTGGCCGTATTGACCGCCGCACTGATCAGCACTGTCGGCTCTGCCCTGAATGCGCTGAGTACCGTCTTCACGAT
GGATATTTATGTCAAGAAATTCAGGCCACTTGCCAGCCAGAAAGAGATCATCCGTACGGGACACGTGGTTACAGTGGCGG
GAGCACTGATTTCGGTGATCATCACCATTGCCATAGACAGTATCAAAGGATTGAATCTGTTCAATGTATTCCAATCGGTA
CTGGGATTTATCGCACCGCCTATGGCGGCTGTTTTCCTGTTCGGCATCTTCTGGAAACGAACTACCACGATGGCTGCCAA
CATGGCATTGACGCTTGGCACGGCGTTCAGCATGGGAGTGGGTATTCTCTATTTATGGGTATTTCCTGCGGAAAAATATA
CAGCATGGCCTCACTTCATGATGCTGTCTTTCTACCTGTTCGTTATCATCAGCGCAGGCATGATCTTGGTATCCTTATGG
GATAAACATCGACAAGAATGTACATTAAATATGAAGAAAGTCATGGAGAAGCCGGCTAAATCCGTTATCCTTGCATGGGC
GTTACTGGCTATTGTCATGGTCGGGCTTTATCTATTCTTCAATGGGCATTAA

Upstream 100 bases:

>100_bases
CGGGTATAGCGACAATGCCAATACGGCCGTAGCGGTAGCCAAGGAACTGATGGGGCTTCATAAATAAACGGAATATTCAT
CTTAATCTGATACATGAATT

Downstream 100 bases:

>100_bases
AAGAAGGAGCAGAAGGCTGAAAAGATTGTATTTTTATATGCCTGCATTTGATATCCCACTTGGGTGGTGAGGCAGTCCCA
CCCCGGTGAGATTGCAGCTT

Product: Na+/glucose cotransporter

Products: NA

Alternate protein names: Na(+)/glucose symporter [H]

Number of amino acids: Translated: 523; Mature: 523

Protein sequence:

>523_residues
MHANYLDTLDWGILIAYFLILIGIGIWASLKRKKGSSLFLAERSLKWHHIGFSMWGTNVGPSMLIASASAGFTTGIVSGN
YAWYAFVFICLLAFVFAPRYLGARITTLPEFMGRRFGQSTRNILAWYTIVTILISWLALTLFAGGILIRQVFDIPMWQSA
LILLVISAFFTMAGGLKAVAYTNVFQMLLLIFVSATLTIAGLYKVGGVSALAEAVPADYWNLFRPNDDPAFPWLPIILGY
PIMGVWFWCTDQSMVQPVLAAKNLKEGQMGANFTGWLKILDVPLYILPGIICLALYPGLKNPDEAYMTMVTNLFPVGMVG
LVLAVLTAALISTVGSALNALSTVFTMDIYVKKFRPLASQKEIIRTGHVVTVAGALISVIITIAIDSIKGLNLFNVFQSV
LGFIAPPMAAVFLFGIFWKRTTTMAANMALTLGTAFSMGVGILYLWVFPAEKYTAWPHFMMLSFYLFVIISAGMILVSLW
DKHRQECTLNMKKVMEKPAKSVILAWALLAIVMVGLYLFFNGH

Sequences:

>Translated_523_residues
MHANYLDTLDWGILIAYFLILIGIGIWASLKRKKGSSLFLAERSLKWHHIGFSMWGTNVGPSMLIASASAGFTTGIVSGN
YAWYAFVFICLLAFVFAPRYLGARITTLPEFMGRRFGQSTRNILAWYTIVTILISWLALTLFAGGILIRQVFDIPMWQSA
LILLVISAFFTMAGGLKAVAYTNVFQMLLLIFVSATLTIAGLYKVGGVSALAEAVPADYWNLFRPNDDPAFPWLPIILGY
PIMGVWFWCTDQSMVQPVLAAKNLKEGQMGANFTGWLKILDVPLYILPGIICLALYPGLKNPDEAYMTMVTNLFPVGMVG
LVLAVLTAALISTVGSALNALSTVFTMDIYVKKFRPLASQKEIIRTGHVVTVAGALISVIITIAIDSIKGLNLFNVFQSV
LGFIAPPMAAVFLFGIFWKRTTTMAANMALTLGTAFSMGVGILYLWVFPAEKYTAWPHFMMLSFYLFVIISAGMILVSLW
DKHRQECTLNMKKVMEKPAKSVILAWALLAIVMVGLYLFFNGH
>Mature_523_residues
MHANYLDTLDWGILIAYFLILIGIGIWASLKRKKGSSLFLAERSLKWHHIGFSMWGTNVGPSMLIASASAGFTTGIVSGN
YAWYAFVFICLLAFVFAPRYLGARITTLPEFMGRRFGQSTRNILAWYTIVTILISWLALTLFAGGILIRQVFDIPMWQSA
LILLVISAFFTMAGGLKAVAYTNVFQMLLLIFVSATLTIAGLYKVGGVSALAEAVPADYWNLFRPNDDPAFPWLPIILGY
PIMGVWFWCTDQSMVQPVLAAKNLKEGQMGANFTGWLKILDVPLYILPGIICLALYPGLKNPDEAYMTMVTNLFPVGMVG
LVLAVLTAALISTVGSALNALSTVFTMDIYVKKFRPLASQKEIIRTGHVVTVAGALISVIITIAIDSIKGLNLFNVFQSV
LGFIAPPMAAVFLFGIFWKRTTTMAANMALTLGTAFSMGVGILYLWVFPAEKYTAWPHFMMLSFYLFVIISAGMILVSLW
DKHRQECTLNMKKVMEKPAKSVILAWALLAIVMVGLYLFFNGH

Specific function: Actively transports glucose into cells by Na(+) cotransport [H]

COG id: COG4146

COG function: function code R; Predicted symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Homo sapiens, GI17941285, Length=458, Percent_Identity=32.9694323144105, Blast_Score=241, Evalue=1e-63,
Organism=Homo sapiens, GI4507031, Length=467, Percent_Identity=32.3340471092077, Blast_Score=234, Evalue=2e-61,
Organism=Homo sapiens, GI109659836, Length=459, Percent_Identity=33.5511982570806, Blast_Score=232, Evalue=6e-61,
Organism=Homo sapiens, GI109659839, Length=475, Percent_Identity=32.2105263157895, Blast_Score=228, Evalue=1e-59,
Organism=Homo sapiens, GI14140236, Length=474, Percent_Identity=30.379746835443, Blast_Score=228, Evalue=2e-59,
Organism=Homo sapiens, GI206597483, Length=459, Percent_Identity=33.1154684095861, Blast_Score=221, Evalue=1e-57,
Organism=Homo sapiens, GI4507033, Length=459, Percent_Identity=30.5010893246187, Blast_Score=217, Evalue=2e-56,
Organism=Homo sapiens, GI110835708, Length=467, Percent_Identity=31.2633832976445, Blast_Score=214, Evalue=2e-55,
Organism=Homo sapiens, GI206597487, Length=484, Percent_Identity=30.9917355371901, Blast_Score=208, Evalue=1e-53,
Organism=Homo sapiens, GI4507035, Length=438, Percent_Identity=23.0593607305936, Blast_Score=100, Evalue=6e-21,
Organism=Homo sapiens, GI167466278, Length=456, Percent_Identity=24.3421052631579, Blast_Score=94, Evalue=4e-19,
Organism=Homo sapiens, GI157671931, Length=471, Percent_Identity=24.8407643312102, Blast_Score=93, Evalue=8e-19,
Organism=Homo sapiens, GI256985183, Length=451, Percent_Identity=22.1729490022173, Blast_Score=81, Evalue=3e-15,
Organism=Escherichia coli, GI1790113, Length=511, Percent_Identity=28.3757338551859, Blast_Score=174, Evalue=2e-44,
Organism=Escherichia coli, GI87082237, Length=376, Percent_Identity=24.2021276595745, Blast_Score=66, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI32566512, Length=384, Percent_Identity=24.4791666666667, Blast_Score=79, Evalue=7e-15,
Organism=Drosophila melanogaster, GI28573698, Length=469, Percent_Identity=23.2409381663113, Blast_Score=92, Evalue=7e-19,
Organism=Drosophila melanogaster, GI281362054, Length=313, Percent_Identity=26.517571884984, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI281362052, Length=313, Percent_Identity=26.517571884984, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI281362050, Length=313, Percent_Identity=26.517571884984, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24648056, Length=313, Percent_Identity=26.517571884984, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI21356827, Length=313, Percent_Identity=26.517571884984, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI28574994, Length=372, Percent_Identity=23.9247311827957, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI221459588, Length=381, Percent_Identity=23.0971128608924, Blast_Score=66, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24648033, Length=400, Percent_Identity=26.75, Blast_Score=65, Evalue=8e-11,
Organism=Drosophila melanogaster, GI21356865, Length=400, Percent_Identity=26.75, Blast_Score=65, Evalue=8e-11,
Organism=Drosophila melanogaster, GI221379702, Length=452, Percent_Identity=21.4601769911504, Blast_Score=65, Evalue=8e-11,
Organism=Drosophila melanogaster, GI24645928, Length=389, Percent_Identity=24.4215938303342, Blast_Score=65, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 57764; Mature: 57764

Theoretical pI: Translated: 9.82; Mature: 9.82

Prosite motif: PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHANYLDTLDWGILIAYFLILIGIGIWASLKRKKGSSLFLAERSLKWHHIGFSMWGTNVG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEECCCEECCCCCC
PSMLIASASAGFTTGIVSGNYAWYAFVFICLLAFVFAPRYLGARITTLPEFMGRRFGQST
HHHHHEECCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHH
RNILAWYTIVTILISWLALTLFAGGILIRQVFDIPMWQSALILLVISAFFTMAGGLKAVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHH
YTNVFQMLLLIFVSATLTIAGLYKVGGVSALAEAVPADYWNLFRPNDDPAFPWLPIILGY
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCHHHHHCCCCCCCCCCCHHHHHHCC
PIMGVWFWCTDQSMVQPVLAAKNLKEGQMGANFTGWLKILDVPLYILPGIICLALYPGLK
HHHHHEEEECCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
NPDEAYMTMVTNLFPVGMVGLVLAVLTAALISTVGSALNALSTVFTMDIYVKKFRPLASQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
KEIIRTGHVVTVAGALISVIITIAIDSIKGLNLFNVFQSVLGFIAPPMAAVFLFGIFWKR
HHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
TTTMAANMALTLGTAFSMGVGILYLWVFPAEKYTAWPHFMMLSFYLFVIISAGMILVSLW
HHHHHHHHHHHHHHHHHHHHHHHHHHEECCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
DKHRQECTLNMKKVMEKPAKSVILAWALLAIVMVGLYLFFNGH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MHANYLDTLDWGILIAYFLILIGIGIWASLKRKKGSSLFLAERSLKWHHIGFSMWGTNVG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEECCCEECCCCCC
PSMLIASASAGFTTGIVSGNYAWYAFVFICLLAFVFAPRYLGARITTLPEFMGRRFGQST
HHHHHEECCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHH
RNILAWYTIVTILISWLALTLFAGGILIRQVFDIPMWQSALILLVISAFFTMAGGLKAVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHH
YTNVFQMLLLIFVSATLTIAGLYKVGGVSALAEAVPADYWNLFRPNDDPAFPWLPIILGY
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCHHHHHCCCCCCCCCCCHHHHHHCC
PIMGVWFWCTDQSMVQPVLAAKNLKEGQMGANFTGWLKILDVPLYILPGIICLALYPGLK
HHHHHEEEECCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
NPDEAYMTMVTNLFPVGMVGLVLAVLTAALISTVGSALNALSTVFTMDIYVKKFRPLASQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
KEIIRTGHVVTVAGALISVIITIAIDSIKGLNLFNVFQSVLGFIAPPMAAVFLFGIFWKR
HHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
TTTMAANMALTLGTAFSMGVGILYLWVFPAEKYTAWPHFMMLSFYLFVIISAGMILVSLW
HHHHHHHHHHHHHHHHHHHHHHHHHHEECCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
DKHRQECTLNMKKVMEKPAKSVILAWALLAIVMVGLYLFFNGH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8652595; 10835424; 10757971 [H]