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The map label for this gene is trpR

Identifier: 148828016

GI number: 148828016

Start: 1411286

End: 1411591

Strand: Direct

Name: trpR

Synonym: CGSHiGG_07655

Alternate gene names: 148828016

Gene position: 1411286-1411591 (Clockwise)

Preceding gene: 148828015

Following gene: 148828017

Centisome position: 74.78

GC content: 36.6

Gene sequence:

>306_bases
ATGTATATCAGCCGTAATTTAGAGCAATGGAATGCATTTCTTCAAATGCTAAAAATCGCCTTTGAAGAAAACAAAGCGCA
GGAATTTCTAACCTTATTATTAACTGCAGACGAACGAGATGCTGTAGGATTGCGCTTGCAGATTGTCTCTCAGCTGATTG
ATAAAAATATGCCTCAGCGTGAAATTCAACAAAATCTGAATACAAGTGCCGCCACAATCACTCGAGGTTCCAATATGATT
AAAACGATGGATCCTGATTTTATGCAATGGATGAAACAACATCTTGATCTCATTGAAAAAAACTAA

Upstream 100 bases:

>100_bases
ATTTTGCAAAATAAAGAAAACCCACAAATCTTTAGCCAAGAAGAATTGAATCGGCTATACTAAATGCACTAGTTTAATAG
TGTAAAATGGGAGCATAATT

Downstream 100 bases:

>100_bases
GCGAATTTTTACCGCACTTTCTCACTTATTTAGTCCTAAATGGTGGAAAAAAACTGGCAGCGAGTTGTCTTTTGTTTTTT
TTTCGCCGTTTTTGCTTTGT

Product: Trp operon repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 101; Mature: 101

Protein sequence:

>101_residues
MYISRNLEQWNAFLQMLKIAFEENKAQEFLTLLLTADERDAVGLRLQIVSQLIDKNMPQREIQQNLNTSAATITRGSNMI
KTMDPDFMQWMKQHLDLIEKN

Sequences:

>Translated_101_residues
MYISRNLEQWNAFLQMLKIAFEENKAQEFLTLLLTADERDAVGLRLQIVSQLIDKNMPQREIQQNLNTSAATITRGSNMI
KTMDPDFMQWMKQHLDLIEKN
>Mature_101_residues
MYISRNLEQWNAFLQMLKIAFEENKAQEFLTLLLTADERDAVGLRLQIVSQLIDKNMPQREIQQNLNTSAATITRGSNMI
KTMDPDFMQWMKQHLDLIEKN

Specific function: This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription

COG id: COG2973

COG function: function code K; Trp operon repressor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpR family

Homologues:

Organism=Escherichia coli, GI1790854, Length=88, Percent_Identity=39.7727272727273, Blast_Score=67, Evalue=2e-13,

Paralogues:

None

Copy number: 250-750 50-300 [C]

Swissprot (AC and ID): TRPR_HAEI8 (Q4QM70)

Other databases:

- EMBL:   CP000057
- RefSeq:   YP_248537.1
- HSSP:   P0A881
- ProteinModelPortal:   Q4QM70
- SMR:   Q4QM70
- STRING:   Q4QM70
- GeneID:   3430300
- GenomeReviews:   CP000057_GR
- KEGG:   hit:NTHI0996
- eggNOG:   COG2973
- HOGENOM:   HBG677773
- OMA:   ELMRGEM
- PhylomeDB:   Q4QM70
- ProtClustDB:   PRK01381
- BioCyc:   HINF281310:NTHI0996-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00475
- InterPro:   IPR000831
- InterPro:   IPR013335
- InterPro:   IPR010921
- Gene3D:   G3DSA:1.10.1270.10
- PIRSF:   PIRSF003196
- ProDom:   PD012582
- TIGRFAMs:   TIGR01321

Pfam domain/function: PF01371 Trp_repressor; SSF48295 Trp_repress_rep

EC number: NA

Molecular weight: Translated: 11872; Mature: 11872

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
6.9 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
6.9 %Met     (Mature Protein)
6.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYISRNLEQWNAFLQMLKIAFEENKAQEFLTLLLTADERDAVGLRLQIVSQLIDKNMPQR
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHH
EIQQNLNTSAATITRGSNMIKTMDPDFMQWMKQHLDLIEKN
HHHHCCCCHHHHHHCCCCCHHCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MYISRNLEQWNAFLQMLKIAFEENKAQEFLTLLLTADERDAVGLRLQIVSQLIDKNMPQR
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHH
EIQQNLNTSAATITRGSNMIKTMDPDFMQWMKQHLDLIEKN
HHHHCCCCHHHHHHCCCCCHHCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA