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The map label for this gene is rpmE [H]

Identifier: 148827949

GI number: 148827949

Start: 1353711

End: 1354847

Strand: Direct

Name: rpmE [H]

Synonym: CGSHiGG_07290

Alternate gene names: 148827949

Gene position: 1353711-1354847 (Clockwise)

Preceding gene: 148827947

Following gene: 148827950

Centisome position: 71.73

GC content: 38.61

Gene sequence:

>1137_bases
ATGTTAGCAAAATCTTCCATCAATGCGCCATTTGCCAAATCTGTTTTAGCTTGGTACGACAAGTTTGGACGCAAGCATTT
ACCTTGGCAGCAAAATAAAACGCTTTATGGTGTATGGCTTTCTGAAGTGATGTTGCAACAAACGCAAGTTGCGACGGTAA
TTCCTTATTTTGAGCGGTTTATCAAAACATTTCCAAATATCACCGCACTTGCCAATGCTTCACAAGATGAAGTGTTACAT
TTATGGACGGGCTTAGGCTATTATGCACGAGCGCGTAATTTACATAAAGCCGCTCAAAAAGTGCGGGATGAATTTAATGG
AAATTTCCCGACAAATTTTGAGCAAGTTTGGGCGTTATCTGGAGTGGGACGTTCAACTGCTGGTGCCATTTTATCTTCTG
TTTTAAATCAGCCTTATCCAATTTTAGATGGTAATGTTAAACGTGTGTTGGCGCGTTATTTTGCTATTGAGGGATGGAGT
GGCGAGAAAAAAGTAGAAAATCGCTTGTGGACATTAACGGAGCAAGTTACACCTACGACGCGTGTGGCAGATTTTAACCA
AGCAATGATGGACATTGGTGCAATGGTTTGCACGCGAACTAAGCCCAAATGCGATCTTTGTCCGTTAAATATAGATTGTT
TGGCTTATAAAAATACAAACTGGGAAAAATTTCCAGCTAAAAAACCTAAAAAAGCGATGCCAGAAAAAACTACCTATTTT
TTAATTTTGTCGAAAAATGGCAAAGTATGTTTGGAACAGCGAGAAAACTCAGGATTATGGGGCGGATTATTTTGTTTTCC
ACAATTTGAAGATAAATCCTCGTTGCTTCATTTTTTAGCCCAAGAAAAAGTCACGCATTATCAAGAATGGCCGAGTTTTC
GACATACATTTAGCCATTTTCATTTAGATATTCATCCAATTTATGCTGAAATGGAGAGTACTTTATGCGTAGAGCAGGCT
AATTTGGACTGGCGAAAAGTGATGGAAAGCACAAAAGAATATCAATCAAACCTATCAAGTGCGGTCAAATATTGGTATGA
TCCACAAAATCCTGAACCGATCGGGCTGGCTCAGCCTGTGAAAAATCTTTTAATACAATTTGTAAGGAATCATTATGGCA
AGAACAGTATTTTGTGA

Upstream 100 bases:

>100_bases
TTGGCACCAAATAGGTTGCGAATTATACTGAAAAAATGCAGATAAACAAGCTCTATTTTCGTGTAAAATCATCAGCATTT
TTAACCGCACTTTTCTTTTT

Downstream 100 bases:

>100_bases
ATATCTCAAAAAAGAAGCGGAAGGCTTAGATTTTCAACTTTATCCAGGAGAGTTGGGGAAGCGTATTTTTGATTCAGTAA
GTAAACAGGCTTGGGGCGAA

Product: 50S ribosomal protein L31

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 378; Mature: 378

Protein sequence:

>378_residues
MLAKSSINAPFAKSVLAWYDKFGRKHLPWQQNKTLYGVWLSEVMLQQTQVATVIPYFERFIKTFPNITALANASQDEVLH
LWTGLGYYARARNLHKAAQKVRDEFNGNFPTNFEQVWALSGVGRSTAGAILSSVLNQPYPILDGNVKRVLARYFAIEGWS
GEKKVENRLWTLTEQVTPTTRVADFNQAMMDIGAMVCTRTKPKCDLCPLNIDCLAYKNTNWEKFPAKKPKKAMPEKTTYF
LILSKNGKVCLEQRENSGLWGGLFCFPQFEDKSSLLHFLAQEKVTHYQEWPSFRHTFSHFHLDIHPIYAEMESTLCVEQA
NLDWRKVMESTKEYQSNLSSAVKYWYDPQNPEPIGLAQPVKNLLIQFVRNHYGKNSIL

Sequences:

>Translated_378_residues
MLAKSSINAPFAKSVLAWYDKFGRKHLPWQQNKTLYGVWLSEVMLQQTQVATVIPYFERFIKTFPNITALANASQDEVLH
LWTGLGYYARARNLHKAAQKVRDEFNGNFPTNFEQVWALSGVGRSTAGAILSSVLNQPYPILDGNVKRVLARYFAIEGWS
GEKKVENRLWTLTEQVTPTTRVADFNQAMMDIGAMVCTRTKPKCDLCPLNIDCLAYKNTNWEKFPAKKPKKAMPEKTTYF
LILSKNGKVCLEQRENSGLWGGLFCFPQFEDKSSLLHFLAQEKVTHYQEWPSFRHTFSHFHLDIHPIYAEMESTLCVEQA
NLDWRKVMESTKEYQSNLSSAVKYWYDPQNPEPIGLAQPVKNLLIQFVRNHYGKNSIL
>Mature_378_residues
MLAKSSINAPFAKSVLAWYDKFGRKHLPWQQNKTLYGVWLSEVMLQQTQVATVIPYFERFIKTFPNITALANASQDEVLH
LWTGLGYYARARNLHKAAQKVRDEFNGNFPTNFEQVWALSGVGRSTAGAILSSVLNQPYPILDGNVKRVLARYFAIEGWS
GEKKVENRLWTLTEQVTPTTRVADFNQAMMDIGAMVCTRTKPKCDLCPLNIDCLAYKNTNWEKFPAKKPKKAMPEKTTYF
LILSKNGKVCLEQRENSGLWGGLFCFPQFEDKSSLLHFLAQEKVTHYQEWPSFRHTFSHFHLDIHPIYAEMESTLCVEQA
NLDWRKVMESTKEYQSNLSSAVKYWYDPQNPEPIGLAQPVKNLLIQFVRNHYGKNSIL

Specific function: Adenine glycosylase active on G-A and C-A mispairs [H]

COG id: COG1194

COG function: function code L; A/G-specific DNA glycosylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Nth/MutY family [H]

Homologues:

Organism=Homo sapiens, GI190358497, Length=357, Percent_Identity=35.2941176470588, Blast_Score=199, Evalue=5e-51,
Organism=Homo sapiens, GI115298648, Length=357, Percent_Identity=35.2941176470588, Blast_Score=198, Evalue=6e-51,
Organism=Homo sapiens, GI115298650, Length=357, Percent_Identity=35.2941176470588, Blast_Score=198, Evalue=6e-51,
Organism=Homo sapiens, GI115298654, Length=357, Percent_Identity=35.2941176470588, Blast_Score=198, Evalue=6e-51,
Organism=Homo sapiens, GI115298652, Length=357, Percent_Identity=35.2941176470588, Blast_Score=198, Evalue=6e-51,
Organism=Homo sapiens, GI6912520, Length=357, Percent_Identity=35.2941176470588, Blast_Score=198, Evalue=7e-51,
Organism=Escherichia coli, GI1789331, Length=360, Percent_Identity=58.3333333333333, Blast_Score=427, Evalue=1e-121,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011257
- InterPro:   IPR004036
- InterPro:   IPR004035
- InterPro:   IPR003651
- InterPro:   IPR003265
- InterPro:   IPR023170
- InterPro:   IPR005760
- InterPro:   IPR000086
- InterPro:   IPR015797 [H]

Pfam domain/function: PF00730 HhH-GPD [H]

EC number: 3.2.2.-

Molecular weight: Translated: 43519; Mature: 43519

Theoretical pI: Translated: 9.32; Mature: 9.32

Prosite motif: PS00764 ENDONUCLEASE_III_1 ; PS01155 ENDONUCLEASE_III_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLAKSSINAPFAKSVLAWYDKFGRKHLPWQQNKTLYGVWLSEVMLQQTQVATVIPYFERF
CCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHH
IKTFPNITALANASQDEVLHLWTGLGYYARARNLHKAAQKVRDEFNGNFPTNFEQVWALS
HHHCCCCEEECCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
GVGRSTAGAILSSVLNQPYPILDGNVKRVLARYFAIEGWSGEKKVENRLWTLTEQVTPTT
CCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCH
RVADFNQAMMDIGAMVCTRTKPKCDLCPLNIDCLAYKNTNWEKFPAKKPKKAMPEKTTYF
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCHHCCCCCCEEE
LILSKNGKVCLEQRENSGLWGGLFCFPQFEDKSSLLHFLAQEKVTHYQEWPSFRHTFSHF
EEECCCCCEEEEECCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
HLDIHPIYAEMESTLCVEQANLDWRKVMESTKEYQSNLSSAVKYWYDPQNPEPIGLAQPV
EEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHH
KNLLIQFVRNHYGKNSIL
HHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MLAKSSINAPFAKSVLAWYDKFGRKHLPWQQNKTLYGVWLSEVMLQQTQVATVIPYFERF
CCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHH
IKTFPNITALANASQDEVLHLWTGLGYYARARNLHKAAQKVRDEFNGNFPTNFEQVWALS
HHHCCCCEEECCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
GVGRSTAGAILSSVLNQPYPILDGNVKRVLARYFAIEGWSGEKKVENRLWTLTEQVTPTT
CCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCH
RVADFNQAMMDIGAMVCTRTKPKCDLCPLNIDCLAYKNTNWEKFPAKKPKKAMPEKTTYF
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCHHCCCCCCEEE
LILSKNGKVCLEQRENSGLWGGLFCFPQFEDKSSLLHFLAQEKVTHYQEWPSFRHTFSHF
EEECCCCCEEEEECCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
HLDIHPIYAEMESTLCVEQANLDWRKVMESTKEYQSNLSSAVKYWYDPQNPEPIGLAQPV
EEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHH
KNLLIQFVRNHYGKNSIL
HHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: 4Fe-4S Cluster [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Glycosylases; Hydrolysing N-glycosyl compounds [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]