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The map label for this gene is gpmA [H]

Identifier: 148827947

GI number: 148827947

Start: 1352561

End: 1353244

Strand: Direct

Name: gpmA [H]

Synonym: CGSHiGG_07280

Alternate gene names: 148827947

Gene position: 1352561-1353244 (Clockwise)

Preceding gene: 148827944

Following gene: 148827949

Centisome position: 71.67

GC content: 37.57

Gene sequence:

>684_bases
ATGGAATTAGTATTTATCCGTCACGGTTTTAGTGAATGGAATGCAAAAAATTTATTCACGGGTTGGCGTGATGTGAATTT
AACTGAACGCGGTGTGGAAGAAGCAAAAGCTGCGGGTAAAAAACTGTTAGACAAAGGTTATGAATTTGACATCGCATTTA
CCTCTGTTTTAACTCGAGCAATCAAAACTTGTAACATCGTGTTAGAAGAATCCCACCAATTATGGATTCCGCAAGTGAAA
AACTGGCGTTTAAATGAGCGTCACTACGGTGCTTTGCAAGGTTTAGATAAAAAAGCGACTGCGGAGCAATACGGTGACGA
ACAAGTTCATATTTGGCGTCGTTCTTATGATATTTCTCCACCAGATTTAGATCCGCAAGATCCAAATTCTGCACACAATG
ACCGTCGTTACGCAAATATTCCATTTGACGTAGTACCAAACGCAGAAAATTTAAAATTAACATTAGAACGAGCATTACCA
TTCTGGGAAGATCAAATTGCGCCAGCAATGCTTTCTGGCAAACGTGTTTTAGTAGTTGCTCACGGTAATTCACTTCGTGC
GTTGGCAAAACATATTATCGGTATTTCTGATGCTGAAATTATGGATTTTGAAATTCCAACAGGTCAGCCTTTAGTTTTAA
AACTTGATGATAAATTAAATTATGTAGAACATTACTATCTTTAA

Upstream 100 bases:

>100_bases
TTGCTAAAGATCAGGAAATCATTCCTTTTAACTTTTAAAGCTAAGGATTTTTTGCTATAAAATGTGCATTCTTTTTATTT
GAAAACATTAGGAGATTCTT

Downstream 100 bases:

>100_bases
TTAAGTTCAACGTATTGTTGTTCTAACTGTATAAAACAAAACCCCGCAAATTAGCGGGGTTTTTAAACAAGTCCAAATTA
TTTTGTGCTTGGAATTTTGA

Product: phosphoglyceromutase

Products: NA

Alternate protein names: BPG-dependent PGAM; PGAM; Phosphoglyceromutase; dPGM [H]

Number of amino acids: Translated: 227; Mature: 227

Protein sequence:

>227_residues
MELVFIRHGFSEWNAKNLFTGWRDVNLTERGVEEAKAAGKKLLDKGYEFDIAFTSVLTRAIKTCNIVLEESHQLWIPQVK
NWRLNERHYGALQGLDKKATAEQYGDEQVHIWRRSYDISPPDLDPQDPNSAHNDRRYANIPFDVVPNAENLKLTLERALP
FWEDQIAPAMLSGKRVLVVAHGNSLRALAKHIIGISDAEIMDFEIPTGQPLVLKLDDKLNYVEHYYL

Sequences:

>Translated_227_residues
MELVFIRHGFSEWNAKNLFTGWRDVNLTERGVEEAKAAGKKLLDKGYEFDIAFTSVLTRAIKTCNIVLEESHQLWIPQVK
NWRLNERHYGALQGLDKKATAEQYGDEQVHIWRRSYDISPPDLDPQDPNSAHNDRRYANIPFDVVPNAENLKLTLERALP
FWEDQIAPAMLSGKRVLVVAHGNSLRALAKHIIGISDAEIMDFEIPTGQPLVLKLDDKLNYVEHYYL
>Mature_227_residues
MELVFIRHGFSEWNAKNLFTGWRDVNLTERGVEEAKAAGKKLLDKGYEFDIAFTSVLTRAIKTCNIVLEESHQLWIPQVK
NWRLNERHYGALQGLDKKATAEQYGDEQVHIWRRSYDISPPDLDPQDPNSAHNDRRYANIPFDVVPNAENLKLTLERALP
FWEDQIAPAMLSGKRVLVVAHGNSLRALAKHIIGISDAEIMDFEIPTGQPLVLKLDDKLNYVEHYYL

Specific function: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate [H]

COG id: COG0588

COG function: function code G; Phosphoglycerate mutase 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily [H]

Homologues:

Organism=Homo sapiens, GI50593010, Length=220, Percent_Identity=51.8181818181818, Blast_Score=246, Evalue=2e-65,
Organism=Homo sapiens, GI4505753, Length=224, Percent_Identity=52.2321428571429, Blast_Score=233, Evalue=9e-62,
Organism=Homo sapiens, GI4502445, Length=225, Percent_Identity=48.4444444444444, Blast_Score=231, Evalue=5e-61,
Organism=Homo sapiens, GI40353764, Length=225, Percent_Identity=48.4444444444444, Blast_Score=231, Evalue=5e-61,
Organism=Homo sapiens, GI71274132, Length=224, Percent_Identity=50.4464285714286, Blast_Score=223, Evalue=1e-58,
Organism=Homo sapiens, GI310129614, Length=161, Percent_Identity=54.0372670807453, Blast_Score=166, Evalue=1e-41,
Organism=Escherichia coli, GI1786970, Length=226, Percent_Identity=53.0973451327434, Blast_Score=253, Evalue=6e-69,
Organism=Saccharomyces cerevisiae, GI6322697, Length=227, Percent_Identity=51.5418502202643, Blast_Score=241, Evalue=6e-65,
Organism=Saccharomyces cerevisiae, GI6324516, Length=280, Percent_Identity=31.4285714285714, Blast_Score=126, Evalue=4e-30,
Organism=Saccharomyces cerevisiae, GI6320183, Length=282, Percent_Identity=31.2056737588652, Blast_Score=121, Evalue=1e-28,
Organism=Saccharomyces cerevisiae, GI6324857, Length=108, Percent_Identity=33.3333333333333, Blast_Score=64, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24646216, Length=221, Percent_Identity=50.2262443438914, Blast_Score=223, Evalue=7e-59,
Organism=Drosophila melanogaster, GI85725270, Length=224, Percent_Identity=52.2321428571429, Blast_Score=216, Evalue=8e-57,
Organism=Drosophila melanogaster, GI85725272, Length=224, Percent_Identity=52.2321428571429, Blast_Score=216, Evalue=8e-57,
Organism=Drosophila melanogaster, GI24650981, Length=224, Percent_Identity=52.2321428571429, Blast_Score=216, Evalue=8e-57,
Organism=Drosophila melanogaster, GI28571815, Length=219, Percent_Identity=38.3561643835616, Blast_Score=162, Evalue=2e-40,
Organism=Drosophila melanogaster, GI28571817, Length=219, Percent_Identity=38.3561643835616, Blast_Score=162, Evalue=2e-40,
Organism=Drosophila melanogaster, GI24648979, Length=219, Percent_Identity=38.3561643835616, Blast_Score=162, Evalue=2e-40,

Paralogues:

None

Copy number: 960 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR005952 [H]

Pfam domain/function: PF00300 PGAM [H]

EC number: =5.4.2.1 [H]

Molecular weight: Translated: 26079; Mature: 26079

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELVFIRHGFSEWNAKNLFTGWRDVNLTERGVEEAKAAGKKLLDKGYEFDIAFTSVLTRA
CEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHH
IKTCNIVLEESHQLWIPQVKNWRLNERHYGALQGLDKKATAEQYGDEQVHIWRRSYDISP
HHHHHEEEECCCEEECCCCCCCCCCCCCCHHHHCCCCHHHHHHCCCCEEEEEEEECCCCC
PDLDPQDPNSAHNDRRYANIPFDVVPNAENLKLTLERALPFWEDQIAPAMLSGKRVLVVA
CCCCCCCCCCCCCCCEEECCCEEECCCCCCEEEEHHHCCCCCHHHCCHHHHCCCEEEEEE
HGNSLRALAKHIIGISDAEIMDFEIPTGQPLVLKLDDKLNYVEHYYL
CCCCHHHHHHHHCCCCCCEEEEEECCCCCEEEEEECCCCCCHHHHCC
>Mature Secondary Structure
MELVFIRHGFSEWNAKNLFTGWRDVNLTERGVEEAKAAGKKLLDKGYEFDIAFTSVLTRA
CEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHH
IKTCNIVLEESHQLWIPQVKNWRLNERHYGALQGLDKKATAEQYGDEQVHIWRRSYDISP
HHHHHEEEECCCEEECCCCCCCCCCCCCCHHHHCCCCHHHHHHCCCCEEEEEEEECCCCC
PDLDPQDPNSAHNDRRYANIPFDVVPNAENLKLTLERALPFWEDQIAPAMLSGKRVLVVA
CCCCCCCCCCCCCCCEEECCCEEECCCCCCEEEEHHHCCCCCHHHCCHHHHCCCEEEEEE
HGNSLRALAKHIIGISDAEIMDFEIPTGQPLVLKLDDKLNYVEHYYL
CCCCHHHHHHHHCCCCCCEEEEEECCCCCEEEEEECCCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA