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The map label for this gene is mdaB [H]

Identifier: 148827826

GI number: 148827826

Start: 1189518

End: 1190006

Strand: Reverse

Name: mdaB [H]

Synonym: CGSHiGG_06520

Alternate gene names: 148827826

Gene position: 1190006-1189518 (Counterclockwise)

Preceding gene: 148827827

Following gene: 148827824

Centisome position: 63.06

GC content: 43.97

Gene sequence:

>489_bases
TTGACCGCACTTGGACACAATGTCAAAGAAACTGTAATTGATGCTGGTTATGACGTTGAAGCTGAAATCGAAAAATTCTT
GTGGATGGATGCCGTGATTTGGCAAATGCCGAGCTGGTGGATGCATGAGCCTTGGACAGTGAAAAAATACATAGACGAAG
TATTAACCAATGGGCACGGCAAGTTATATCACAGTGATGGCAGACACAGCGTTAATCCAACCGAGGGCTATGGCACAGGC
GGCTTGTTGCAAGGAAAAAAACACATGCTTTCACTGACTTGGAATGCACCGATTGAAGCCTTTACTCGCGAAGGCGATTT
CTTTGAAGGCAAAGGCGTGGATGTTTTGTATATGCATTTCCACAAACTCAACGAGTTCCTCGGTTTGACTCGCCTGCCGA
CATTCTTATGTAACGATGTGGTTAAAAGTCCGCAAGTAGAACAATACTTAGCAGACTACCAAGCACATTTGGAAAAAGTG
TTTGGTTAA

Upstream 100 bases:

>100_bases
AGCAAAAAGATGAATATTTTATTATTAGACGGCGGTAAGGCGTTTGGTCATTCTCACGGCGAGTTGAACCACACGCTTCA
CAAAAAAAGCGAAAGAAGTT

Downstream 100 bases:

>100_bases
TAAAAAAATCCATCTTCAATACGAAGATGGATTTTTTGTTTATTTCGTTGAGATTGTTGTTACTTAACAACTGCCCCACA
AATCATATTCATCAGAATTT

Product: modulator of drug activity B

Products: NADP; a reduced quinone; reduced acceptor [C]

Alternate protein names: NA

Number of amino acids: Translated: 162; Mature: 161

Protein sequence:

>162_residues
MTALGHNVKETVIDAGYDVEAEIEKFLWMDAVIWQMPSWWMHEPWTVKKYIDEVLTNGHGKLYHSDGRHSVNPTEGYGTG
GLLQGKKHMLSLTWNAPIEAFTREGDFFEGKGVDVLYMHFHKLNEFLGLTRLPTFLCNDVVKSPQVEQYLADYQAHLEKV
FG

Sequences:

>Translated_162_residues
MTALGHNVKETVIDAGYDVEAEIEKFLWMDAVIWQMPSWWMHEPWTVKKYIDEVLTNGHGKLYHSDGRHSVNPTEGYGTG
GLLQGKKHMLSLTWNAPIEAFTREGDFFEGKGVDVLYMHFHKLNEFLGLTRLPTFLCNDVVKSPQVEQYLADYQAHLEKV
FG
>Mature_161_residues
TALGHNVKETVIDAGYDVEAEIEKFLWMDAVIWQMPSWWMHEPWTVKKYIDEVLTNGHGKLYHSDGRHSVNPTEGYGTGG
LLQGKKHMLSLTWNAPIEAFTREGDFFEGKGVDVLYMHFHKLNEFLGLTRLPTFLCNDVVKSPQVEQYLADYQAHLEKVF
G

Specific function: Unknown

COG id: COG2249

COG function: function code R; Putative NADPH-quinone reductase (modulator of drug activity B)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: To E.coli madB and S.pombe SPAC5H10.05c [H]

Homologues:

Organism=Escherichia coli, GI1789406, Length=159, Percent_Identity=60.377358490566, Blast_Score=215, Evalue=1e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003680 [H]

Pfam domain/function: PF02525 Flavodoxin_2 [H]

EC number: NA

Molecular weight: Translated: 18616; Mature: 18485

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTALGHNVKETVIDAGYDVEAEIEKFLWMDAVIWQMPSWWMHEPWTVKKYIDEVLTNGHG
CCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCC
KLYHSDGRHSVNPTEGYGTGGLLQGKKHMLSLTWNAPIEAFTREGDFFEGKGVDVLYMHF
EEEECCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCHHHHHCCCCCCCCCCCCHHHHHH
HKLNEFLGLTRLPTFLCNDVVKSPQVEQYLADYQAHLEKVFG
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TALGHNVKETVIDAGYDVEAEIEKFLWMDAVIWQMPSWWMHEPWTVKKYIDEVLTNGHG
CCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCC
KLYHSDGRHSVNPTEGYGTGGLLQGKKHMLSLTWNAPIEAFTREGDFFEGKGVDVLYMHF
EEEECCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCHHHHHCCCCCCCCCCCCHHHHHH
HKLNEFLGLTRLPTFLCNDVVKSPQVEQYLADYQAHLEKVFG
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NADPH; a quinone; Acceptor; NADPH [C]

Specific reaction: NADPH + a quinone = NADP + a reduced quinone Acceptor + NADPH = reduced acceptor + NADP [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]