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The map label for this gene is hflK [H]

Identifier: 148827292

GI number: 148827292

Start: 624061

End: 625281

Strand: Reverse

Name: hflK [H]

Synonym: CGSHiGG_03345

Alternate gene names: 148827292

Gene position: 625281-624061 (Counterclockwise)

Preceding gene: 148827293

Following gene: 148827291

Centisome position: 33.13

GC content: 40.95

Gene sequence:

>1221_bases
ATGTCACAGAACGGTTCAGATCGCGATCCTTGGAGTAAACCAGGGCAAAGCAACGACCAACAGCCGGGAAATTCATCCAA
TAATAATGGATGGAATAACAATCAAAATCGTGGAAATCAAGAGCAATCTCCGCCAGATATTGAGGAGATTTTTAATAATC
TGCTTAAAAAATTAGGTGGTGGAAATAAAAAGAGCGGTCAAAATAATGGCAGTTCTCAAGGCAATACGCCATTTCATTTT
GGCAAAGTTATTCCACTTGCTGTAGCGATTGGTGCAATTATTTGGGGCGTAAGCGGTTTTTACACCATTAAAGAGGCTGA
ACGCGGTGTGGTGCTTCGTTTTGGCGAGTTACATTCTATTGTTCAACCCGGTTTGAACTGGAAACCAACATTTGTAGATA
AAGTATTGCCAGTAAATGTGGAGCAAGTAAAAGAGTTGCGTACACAAGGTGCAATGCTGACTCAAGATGAAAATATGGTA
AAAGTGGAAATGACCGTGCAATATCGCGTGCAAGATCCTGCAAAATATCTTTTTAGCGTAACAAATGCAGATGATAGTTT
GAATCAAGCGACAGATAGTGCATTACGTTATGTTATTGGGCATATGTCTATGAATGATATTTTAACCACAGGTCGCTCTG
TCGTGCGTGAAAATACTTGGAAAGCTTTGAATGAAATTATCAAATCCTATGATATGGGACTTGAGGTTATTGATGTGAAC
TTCCAATCTGCTCGTCCACCTGAAGAAGTAAAAGATGCGTTTGATGATGCAATTAAAGCGCAGGAAGATGAACAACGTTT
TATTCGTGAAGCGGAAGCCTATGCGCGTGAGAAAGAACCGATTGCACGTGGTGATGCGCAACGTATTCTTGAAGAAGCAA
CAGCTTATAAAGATCGTATCGTGTTAGATGCAAAAGGTGAAGTGGAACGTTTGCAACGCTTGTTGCCAGAATTTAAGGCT
GCACCAGATTTACTGCGTGAGCGTTTATATATTCAGACGATGGAAAAAGTGATGGCAAATACCCCAAAAGTAATGCTTGA
TGGCAATAATGGTAATAATTTAACTGTGTTACCGCTAGAGCAAATTATGGGCAAAAAATCGGTAACAAGTGCGCCAAGTG
CGGTCAATTCTTCGCCTGCTTTTACTGCACCAGAACGTCAAAATTCTTATCAGCCTCAGCCGACTACCGTTGCGCCGATT
CGTCAAGGGAGATTTAACTAA

Upstream 100 bases:

>100_bases
ATCAAGGATTTTTTATTGCCTAAAAAGGCTTGTATTTTCATAGACGTGCCCCATTTATTTAGCTAAACTCTTAACAATTT
TTTGACAAATGGAGAATGAA

Downstream 100 bases:

>100_bases
TGCGTAGATTTTTATTACCTGTTATTTTCGTGATTGCGGCAGTCGTTTATTCTAGTATCGTCGTTGTAACGGAAGGTACC
CGTGGCATTATGTTACGATT

Product: FtsH protease regulator HflK

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 406; Mature: 405

Protein sequence:

>406_residues
MSQNGSDRDPWSKPGQSNDQQPGNSSNNNGWNNNQNRGNQEQSPPDIEEIFNNLLKKLGGGNKKSGQNNGSSQGNTPFHF
GKVIPLAVAIGAIIWGVSGFYTIKEAERGVVLRFGELHSIVQPGLNWKPTFVDKVLPVNVEQVKELRTQGAMLTQDENMV
KVEMTVQYRVQDPAKYLFSVTNADDSLNQATDSALRYVIGHMSMNDILTTGRSVVRENTWKALNEIIKSYDMGLEVIDVN
FQSARPPEEVKDAFDDAIKAQEDEQRFIREAEAYAREKEPIARGDAQRILEEATAYKDRIVLDAKGEVERLQRLLPEFKA
APDLLRERLYIQTMEKVMANTPKVMLDGNNGNNLTVLPLEQIMGKKSVTSAPSAVNSSPAFTAPERQNSYQPQPTTVAPI
RQGRFN

Sequences:

>Translated_406_residues
MSQNGSDRDPWSKPGQSNDQQPGNSSNNNGWNNNQNRGNQEQSPPDIEEIFNNLLKKLGGGNKKSGQNNGSSQGNTPFHF
GKVIPLAVAIGAIIWGVSGFYTIKEAERGVVLRFGELHSIVQPGLNWKPTFVDKVLPVNVEQVKELRTQGAMLTQDENMV
KVEMTVQYRVQDPAKYLFSVTNADDSLNQATDSALRYVIGHMSMNDILTTGRSVVRENTWKALNEIIKSYDMGLEVIDVN
FQSARPPEEVKDAFDDAIKAQEDEQRFIREAEAYAREKEPIARGDAQRILEEATAYKDRIVLDAKGEVERLQRLLPEFKA
APDLLRERLYIQTMEKVMANTPKVMLDGNNGNNLTVLPLEQIMGKKSVTSAPSAVNSSPAFTAPERQNSYQPQPTTVAPI
RQGRFN
>Mature_405_residues
SQNGSDRDPWSKPGQSNDQQPGNSSNNNGWNNNQNRGNQEQSPPDIEEIFNNLLKKLGGGNKKSGQNNGSSQGNTPFHFG
KVIPLAVAIGAIIWGVSGFYTIKEAERGVVLRFGELHSIVQPGLNWKPTFVDKVLPVNVEQVKELRTQGAMLTQDENMVK
VEMTVQYRVQDPAKYLFSVTNADDSLNQATDSALRYVIGHMSMNDILTTGRSVVRENTWKALNEIIKSYDMGLEVIDVNF
QSARPPEEVKDAFDDAIKAQEDEQRFIREAEAYAREKEPIARGDAQRILEEATAYKDRIVLDAKGEVERLQRLLPEFKAA
PDLLRERLYIQTMEKVMANTPKVMLDGNNGNNLTVLPLEQIMGKKSVTSAPSAVNSSPAFTAPERQNSYQPQPTTVAPIR
QGRFN

Specific function: HflC and HflK could encode or regulate a protease [H]

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family. HflK subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790616, Length=384, Percent_Identity=55.9895833333333, Blast_Score=382, Evalue=1e-107,
Organism=Escherichia coli, GI1786697, Length=225, Percent_Identity=23.1111111111111, Blast_Score=65, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001107
- InterPro:   IPR010201
- InterPro:   IPR001972 [H]

Pfam domain/function: PF01145 Band_7 [H]

EC number: NA

Molecular weight: Translated: 45276; Mature: 45145

Theoretical pI: Translated: 5.38; Mature: 5.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQNGSDRDPWSKPGQSNDQQPGNSSNNNGWNNNQNRGNQEQSPPDIEEIFNNLLKKLGG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCC
GNKKSGQNNGSSQGNTPFHFGKVIPLAVAIGAIIWGVSGFYTIKEAERGVVLRFGELHSI
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCEEEEHHHHHHH
VQPGLNWKPTFVDKVLPVNVEQVKELRTQGAMLTQDENMVKVEMTVQYRVQDPAKYLFSV
HCCCCCCCCHHHHHHCCCCHHHHHHHHHCCCEEECCCCEEEEEEEEEEEECCHHHHHHHH
TNADDSLNQATDSALRYVIGHMSMNDILTTGRSVVRENTWKALNEIIKSYDMGLEVIDVN
CCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEC
FQSARPPEEVKDAFDDAIKAQEDEQRFIREAEAYAREKEPIARGDAQRILEEATAYKDRI
CCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCEE
VLDAKGEVERLQRLLPEFKAAPDLLRERLYIQTMEKVMANTPKVMLDGNNGNNLTVLPLE
EEECCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEEEEHH
QIMGKKSVTSAPSAVNSSPAFTAPERQNSYQPQPTTVAPIRQGRFN
HHCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCC
>Mature Secondary Structure 
SQNGSDRDPWSKPGQSNDQQPGNSSNNNGWNNNQNRGNQEQSPPDIEEIFNNLLKKLGG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCC
GNKKSGQNNGSSQGNTPFHFGKVIPLAVAIGAIIWGVSGFYTIKEAERGVVLRFGELHSI
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCEEEEHHHHHHH
VQPGLNWKPTFVDKVLPVNVEQVKELRTQGAMLTQDENMVKVEMTVQYRVQDPAKYLFSV
HCCCCCCCCHHHHHHCCCCHHHHHHHHHCCCEEECCCCEEEEEEEEEEEECCHHHHHHHH
TNADDSLNQATDSALRYVIGHMSMNDILTTGRSVVRENTWKALNEIIKSYDMGLEVIDVN
CCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEC
FQSARPPEEVKDAFDDAIKAQEDEQRFIREAEAYAREKEPIARGDAQRILEEATAYKDRI
CCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCEE
VLDAKGEVERLQRLLPEFKAAPDLLRERLYIQTMEKVMANTPKVMLDGNNGNNLTVLPLE
EEECCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEEEEHH
QIMGKKSVTSAPSAVNSSPAFTAPERQNSYQPQPTTVAPIRQGRFN
HHCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]