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The map label for this gene is hsaA [H]

Identifier: 148824286

GI number: 148824286

Start: 3474525

End: 3475655

Strand: Reverse

Name: hsaA [H]

Synonym: TBFG_13111

Alternate gene names: 148824286

Gene position: 3475655-3474525 (Counterclockwise)

Preceding gene: 148824289

Following gene: 148824285

Centisome position: 78.56

GC content: 68.61

Gene sequence:

>1131_bases
GTGAACCAAAGCGAAACCGAGATCGAGATCCTCGCCGAGAAGATCGCGCGGTGGGCCCGAGCGCGATCCGCGGAAATCGA
GCGCGATCGTCGGCTGCCAGACGAGCTGGTGACCCGGCTGCGCGAGGCCGGCTTGCTGCGCGCCACCATGCCGCGTGAGG
TTGCGGCGCCGGAGCTGGCACCCGGGCGGGCGCTGCGGTGCGCCGAGGCGGTGGCGCGTGGTGACGCGTCAGCGGGATGG
TGTGTGTCGATCGCGATTACCAGTGCCCTGCTGGTCGCCTACCTGCCGGCGCGCAGCCGCGAGGAAATGTTCGGCGGGGG
GCGGGGTGTCGCGGCGGGGGTGTGGGCGCCACGTGGCACGGCCCGGTCCGTCGACGGCGGTGTCGTGGTGTCCGGACGCT
GGCCGTTTTGCAGCGGGATCAACCACGCGGACATCATGTTCGCCGGCTGCTTCGTCGACGACCGGCAAGTGCCGTCGGTC
GTCGCGCTGAACAAGGACGAGCTGCAGGTCCTCGACACTTGGCACACATTGGGTTTGCGTGGCACCGGCAGCCACGACTG
CGTTGCCGACGACGTCTTCGTGCCCGCTGATCGCGTGTTCTCGGTGTTTGACGGACCAATCGTGGACCGGCCGCTGTATC
GCTTTCCGGTGTTTGGATTTTTCGCGTTGTCGATTGGCGCGGCTGCGTTGGGCAATGCGCGCGCCGCGATTGACGATCTG
GTCGAGCTGGCCGGCGGCAAGAAAGGGCTTGGGTCCACTCGGACCTTGGCGGAACGTTCGGCGACCCAAGCCGCGGCGGC
AACCGCCGAGTCGGCGCTGGGCGCCGCCCGCGCCCTGTTCTACGAGGTAATCGAGGCGGCCTGGCAGGTCAGCCACGATG
CCGAGGCGGTACCGGTGACGATGCGCAACCGGCTGCGGTTGGCGGCCACGCACGCGGTACGGACCTCGGCCGACGTGGTG
CGCAGCATGTATGATCTGGCGGGCGGCACCGCCATCTACGACAACGCACCGCTGCAGCGCCGGTTCCGCGACGCATTCAC
CGCTACCGCCCATTTCCAGGTCAACGAGGCATCACGCGAACTGCCCGGGCGTGTCCTGCTCGACCAGCCGGCCGACGTGT
CGATGCTATGA

Upstream 100 bases:

>100_bases
ATAGATCGGAAACGGCCATGGTCCACCAACTGTACCTGGTTCAATGACTGAACCAAGGGTGGTAACTTCATTGAACCGCC
ACCGTCATCAGGAGCCGCCC

Downstream 100 bases:

>100_bases
CCGATATCGAAGTCGCCCTACCGTTCTGGCTTGACCGCCCCGACCACGAGGCAACCGATGTCGCGCTCGCGGCCGCTGAC
ACGGGTTTCGCTGCGCTGTG

Product: hypothetical protein

Products: NA

Alternate protein names: 3-hydroxy-9,10-seconandrost-1,3,5(10)-triene-9,17-dione 4-hydroxylase [H]

Number of amino acids: Translated: 376; Mature: 376

Protein sequence:

>376_residues
MNQSETEIEILAEKIARWARARSAEIERDRRLPDELVTRLREAGLLRATMPREVAAPELAPGRALRCAEAVARGDASAGW
CVSIAITSALLVAYLPARSREEMFGGGRGVAAGVWAPRGTARSVDGGVVVSGRWPFCSGINHADIMFAGCFVDDRQVPSV
VALNKDELQVLDTWHTLGLRGTGSHDCVADDVFVPADRVFSVFDGPIVDRPLYRFPVFGFFALSIGAAALGNARAAIDDL
VELAGGKKGLGSTRTLAERSATQAAAATAESALGAARALFYEVIEAAWQVSHDAEAVPVTMRNRLRLAATHAVRTSADVV
RSMYDLAGGTAIYDNAPLQRRFRDAFTATAHFQVNEASRELPGRVLLDQPADVSML

Sequences:

>Translated_376_residues
MNQSETEIEILAEKIARWARARSAEIERDRRLPDELVTRLREAGLLRATMPREVAAPELAPGRALRCAEAVARGDASAGW
CVSIAITSALLVAYLPARSREEMFGGGRGVAAGVWAPRGTARSVDGGVVVSGRWPFCSGINHADIMFAGCFVDDRQVPSV
VALNKDELQVLDTWHTLGLRGTGSHDCVADDVFVPADRVFSVFDGPIVDRPLYRFPVFGFFALSIGAAALGNARAAIDDL
VELAGGKKGLGSTRTLAERSATQAAAATAESALGAARALFYEVIEAAWQVSHDAEAVPVTMRNRLRLAATHAVRTSADVV
RSMYDLAGGTAIYDNAPLQRRFRDAFTATAHFQVNEASRELPGRVLLDQPADVSML
>Mature_376_residues
MNQSETEIEILAEKIARWARARSAEIERDRRLPDELVTRLREAGLLRATMPREVAAPELAPGRALRCAEAVARGDASAGW
CVSIAITSALLVAYLPARSREEMFGGGRGVAAGVWAPRGTARSVDGGVVVSGRWPFCSGINHADIMFAGCFVDDRQVPSV
VALNKDELQVLDTWHTLGLRGTGSHDCVADDVFVPADRVFSVFDGPIVDRPLYRFPVFGFFALSIGAAALGNARAAIDDL
VELAGGKKGLGSTRTLAERSATQAAAATAESALGAARALFYEVIEAAWQVSHDAEAVPVTMRNRLRLAATHAVRTSADVV
RSMYDLAGGTAIYDNAPLQRRFRDAFTATAHFQVNEASRELPGRVLLDQPADVSML

Specific function: Catalyzes the o-hydroxylation of 3-hydroxy-9,10- seconandrost-1,3,5(10)-triene-9,17-dione (3-HSA) to 3,4-dihydroxy- 9,10-seconandrost-1,3,5(10)-triene-9,17-dione (3,4-DHSA) in the catabolism of cholesterol [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FADH(2)-utilizing monooxygenase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013107
- InterPro:   IPR006092
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF08028 Acyl-CoA_dh_2; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 40329; Mature: 40329

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQSETEIEILAEKIARWARARSAEIERDRRLPDELVTRLREAGLLRATMPREVAAPELA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHCCCHHHCCCCCC
PGRALRCAEAVARGDASAGWCVSIAITSALLVAYLPARSREEMFGGGRGVAAGVWAPRGT
CCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCEECCCCCCCC
ARSVDGGVVVSGRWPFCSGINHADIMFAGCFVDDRQVPSVVALNKDELQVLDTWHTLGLR
CCCCCCCEEEECCCCCCCCCCCCCEEEEEEEECCCCCCCEEEECCHHHHHHHHHHHHCCC
GTGSHDCVADDVFVPADRVFSVFDGPIVDRPLYRFPVFGFFALSIGAAALGNARAAIDDL
CCCCCCCCCCCEECCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
VELAGGKKGLGSTRTLAERSATQAAAATAESALGAARALFYEVIEAAWQVSHDAEAVPVT
HHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHH
MRNRLRLAATHAVRTSADVVRSMYDLAGGTAIYDNAPLQRRFRDAFTATAHFQVNEASRE
HHHCCHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHEEEEEEECCHHHC
LPGRVLLDQPADVSML
CCCCEEECCCCCCCCC
>Mature Secondary Structure
MNQSETEIEILAEKIARWARARSAEIERDRRLPDELVTRLREAGLLRATMPREVAAPELA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHCCCHHHCCCCCC
PGRALRCAEAVARGDASAGWCVSIAITSALLVAYLPARSREEMFGGGRGVAAGVWAPRGT
CCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCEECCCCCCCC
ARSVDGGVVVSGRWPFCSGINHADIMFAGCFVDDRQVPSVVALNKDELQVLDTWHTLGLR
CCCCCCCEEEECCCCCCCCCCCCCEEEEEEEECCCCCCCEEEECCHHHHHHHHHHHHCCC
GTGSHDCVADDVFVPADRVFSVFDGPIVDRPLYRFPVFGFFALSIGAAALGNARAAIDDL
CCCCCCCCCCCEECCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
VELAGGKKGLGSTRTLAERSATQAAAATAESALGAARALFYEVIEAAWQVSHDAEAVPVT
HHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHH
MRNRLRLAATHAVRTSADVVRSMYDLAGGTAIYDNAPLQRRFRDAFTATAHFQVNEASRE
HHHCCHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHEEEEEEECCHHHC
LPGRVLLDQPADVSML
CCCCEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA