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The map label for this gene is 148824240

Identifier: 148824240

GI number: 148824240

Start: 3421219

End: 3422793

Strand: Reverse

Name: 148824240

Synonym: TBFG_13065

Alternate gene names: NA

Gene position: 3422793-3421219 (Counterclockwise)

Preceding gene: 148824241

Following gene: 148824239

Centisome position: 77.36

GC content: 64.06

Gene sequence:

>1575_bases
GTGAGCATTGCCGATACGGCTGCCAAGCCGTCCACGCCAAGCCCGGCCAACCAGCCGCCGGTACGTACCCGCGCCGTCAT
CATCGGAACCGGATTCTCCGGTTTGGGCATGGCCATCGCACTGCAAAAGCAAGGAGTGGACTTCGTCATATTGGAGAAAG
CCGACGACGTCGGCGGCACCTGGCGCGACAACACCTACCCCGGCTGCGCGTGCGACATCCCGTCGCACCTGTACTCCTTC
TCGTTCGAGCCCAAGGCGGACTGGAAACACCTGTTTTCCTACTGGGACGAAATCTTGGGCTACCTCAAAGGGGTCACCGA
CAAGTACGGCCTGCGCCGCTACATCGAGTTCAATTCGCTCGTCGATCGCGGCTACTGGGACGACGACGAATGCCGCTGGC
ACGTGTTCACCGCCGACGGGCGTGAATACGTCGCGCAGTTCCTGATCTCCGGGGCCGGTGCGTTGCACATCCCGTCCTTC
CCCGAGATCGCAGGTCGCGACGAATTCGCCGGCCCCGCTTTCCATTCCGCCCAGTGGGACCACAGTATCGACCTGACCGG
CAAGCGGGTGGCGATCGTCGGGACCGGTGCCAGCGCGATCCAGATCGTGCCCGAGATCGTCGGCCAGGTCGCCGAACTTC
AGCTCTATCAGCGCACCCCGCCGTGGGTGGTCCCGCGCACCAACGAAGAGCTGCCGGTGTCGCTGCGCCGGGCGTTGCGA
ACCGTCCCCGGGCTACGGGCACTGTTGCGCCTCGGCATCTACTGGGCCCAGGAGGCGCTGGCCTACGGCATGACCAAGCG
GCCCAACACGTTGAAGATCATCGAGGCCTATGCCAAATACAATATTCGTCGATCGGTGAAGGATCGCGAGCTGCGGCGCA
AGCTGACGCCGCGGTATCGCATCGGCTGCAAACGGATCCTGAACTCCTCTACCTATTACCCCGCGGTGGCGGACCCGAAG
ACCGAACTGATCACCGACCGCATCGACCGGATCACGCACGACGGGATCGTCACCGCCGACGGCACTGGCCGTGAGGTCTT
CCGGGAAGCCGATGTGATCGTGTACGCCACCGGCTTCCACGTCACCGACTCCTATACCTATGTGCAGATCAAGGGGCGTC
ACGGCGAGGACCTGGTCGACCGCTGGAACCGTGAGGGCATCGGTGCACACCGCGGGATCACCGTCGCCAACATGCCCAAC
CTGTTCTTCCTGCTGGGGCCGAACACTGGGCTGGGACACAACTCCGTGGTGTTCATGATCGAATCGCAGATCCATTACGT
GGCCGATGCGATCGCGAAATGCGACCGGATGGGCGTGCAAGCGCTGGCCCCCACCCGCGAGGCGCAAGACCGGTTCAACC
AGGAGCTGCAGCGCAGGCTGGCTGGGTCGGTGTGGAACAGTGGCGGCTGCCGCAGCTGGTATCTCGACGAGCACGGCAAG
AACACCGTGCTCTGGTGCGGCTACACCTGGCAATACTGGCTGACCACCCGCTCGGTCAACCCCGCCGAGTACCGGTTCTT
CGGGATCGGCAACGGTTTGTCGAGCGACCGCGCGACGGTCGCTGCGGCGAACTAG

Upstream 100 bases:

>100_bases
ACAACACTCGTCATATCCGATACCCTGGGTACTGGGTATTTGCGCCGGCGAGGGTGACTGAAGCGCCAAACTCGCCGCTG
AACAGGAAGACCGATCCATT

Downstream 100 bases:

>100_bases
CCGGCGAAACAGGCGAGCGGATTCGCGACACGCAAACACAACTTCTTGTGTTGCAGTACCTTGTCGGACCCCAGGGGTAG
TGTTTGAGGCCTAGCAAGGC

Product: monooxygenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 524; Mature: 523

Protein sequence:

>524_residues
MSIADTAAKPSTPSPANQPPVRTRAVIIGTGFSGLGMAIALQKQGVDFVILEKADDVGGTWRDNTYPGCACDIPSHLYSF
SFEPKADWKHLFSYWDEILGYLKGVTDKYGLRRYIEFNSLVDRGYWDDDECRWHVFTADGREYVAQFLISGAGALHIPSF
PEIAGRDEFAGPAFHSAQWDHSIDLTGKRVAIVGTGASAIQIVPEIVGQVAELQLYQRTPPWVVPRTNEELPVSLRRALR
TVPGLRALLRLGIYWAQEALAYGMTKRPNTLKIIEAYAKYNIRRSVKDRELRRKLTPRYRIGCKRILNSSTYYPAVADPK
TELITDRIDRITHDGIVTADGTGREVFREADVIVYATGFHVTDSYTYVQIKGRHGEDLVDRWNREGIGAHRGITVANMPN
LFFLLGPNTGLGHNSVVFMIESQIHYVADAIAKCDRMGVQALAPTREAQDRFNQELQRRLAGSVWNSGGCRSWYLDEHGK
NTVLWCGYTWQYWLTTRSVNPAEYRFFGIGNGLSSDRATVAAAN

Sequences:

>Translated_524_residues
MSIADTAAKPSTPSPANQPPVRTRAVIIGTGFSGLGMAIALQKQGVDFVILEKADDVGGTWRDNTYPGCACDIPSHLYSF
SFEPKADWKHLFSYWDEILGYLKGVTDKYGLRRYIEFNSLVDRGYWDDDECRWHVFTADGREYVAQFLISGAGALHIPSF
PEIAGRDEFAGPAFHSAQWDHSIDLTGKRVAIVGTGASAIQIVPEIVGQVAELQLYQRTPPWVVPRTNEELPVSLRRALR
TVPGLRALLRLGIYWAQEALAYGMTKRPNTLKIIEAYAKYNIRRSVKDRELRRKLTPRYRIGCKRILNSSTYYPAVADPK
TELITDRIDRITHDGIVTADGTGREVFREADVIVYATGFHVTDSYTYVQIKGRHGEDLVDRWNREGIGAHRGITVANMPN
LFFLLGPNTGLGHNSVVFMIESQIHYVADAIAKCDRMGVQALAPTREAQDRFNQELQRRLAGSVWNSGGCRSWYLDEHGK
NTVLWCGYTWQYWLTTRSVNPAEYRFFGIGNGLSSDRATVAAAN
>Mature_523_residues
SIADTAAKPSTPSPANQPPVRTRAVIIGTGFSGLGMAIALQKQGVDFVILEKADDVGGTWRDNTYPGCACDIPSHLYSFS
FEPKADWKHLFSYWDEILGYLKGVTDKYGLRRYIEFNSLVDRGYWDDDECRWHVFTADGREYVAQFLISGAGALHIPSFP
EIAGRDEFAGPAFHSAQWDHSIDLTGKRVAIVGTGASAIQIVPEIVGQVAELQLYQRTPPWVVPRTNEELPVSLRRALRT
VPGLRALLRLGIYWAQEALAYGMTKRPNTLKIIEAYAKYNIRRSVKDRELRRKLTPRYRIGCKRILNSSTYYPAVADPKT
ELITDRIDRITHDGIVTADGTGREVFREADVIVYATGFHVTDSYTYVQIKGRHGEDLVDRWNREGIGAHRGITVANMPNL
FFLLGPNTGLGHNSVVFMIESQIHYVADAIAKCDRMGVQALAPTREAQDRFNQELQRRLAGSVWNSGGCRSWYLDEHGKN
TVLWCGYTWQYWLTTRSVNPAEYRFFGIGNGLSSDRATVAAAN

Specific function: Unknown

COG id: COG2072

COG function: function code P; Predicted flavoprotein involved in K+ transport

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-binding monooxygenase family [H]

Homologues:

Organism=Homo sapiens, GI4503757, Length=366, Percent_Identity=25.9562841530055, Blast_Score=89, Evalue=8e-18,
Organism=Homo sapiens, GI50541965, Length=221, Percent_Identity=26.2443438914027, Blast_Score=69, Evalue=9e-12,
Organism=Homo sapiens, GI50541961, Length=221, Percent_Identity=26.2443438914027, Blast_Score=69, Evalue=9e-12,
Organism=Homo sapiens, GI221316674, Length=228, Percent_Identity=27.1929824561404, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI221316672, Length=228, Percent_Identity=27.1929824561404, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI221316678, Length=228, Percent_Identity=27.1929824561404, Blast_Score=69, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI25145785, Length=218, Percent_Identity=26.605504587156, Blast_Score=83, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17541300, Length=220, Percent_Identity=25.4545454545455, Blast_Score=71, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020946 [H]

Pfam domain/function: PF00743 FMO-like [H]

EC number: NA

Molecular weight: Translated: 58777; Mature: 58646

Theoretical pI: Translated: 8.42; Mature: 8.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIADTAAKPSTPSPANQPPVRTRAVIIGTGFSGLGMAIALQKQGVDFVILEKADDVGGT
CCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCEEEEEECCCCCEEEEECCCCCCCC
WRDNTYPGCACDIPSHLYSFSFEPKADWKHLFSYWDEILGYLKGVTDKYGLRRYIEFNSL
CCCCCCCCEEECCCHHHHEECCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
VDRGYWDDDECRWHVFTADGREYVAQFLISGAGALHIPSFPEIAGRDEFAGPAFHSAQWD
HHCCCCCCCCCEEEEEECCCHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCCCCCCCC
HSIDLTGKRVAIVGTGASAIQIVPEIVGQVAELQLYQRTPPWVVPRTNEELPVSLRRALR
CEECCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHEECCCCEEECCCCCCCCHHHHHHHH
TVPGLRALLRLGIYWAQEALAYGMTKRPNTLKIIEAYAKYNIRRSVKDRELRRKLTPRYR
HCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
IGCKRILNSSTYYPAVADPKTELITDRIDRITHDGIVTADGTGREVFREADVIVYATGFH
HHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEECCCCHHHHHCCCEEEEEECEE
VTDSYTYVQIKGRHGEDLVDRWNREGIGAHRGITVANMPNLFFLLGPNTGLGHNSVVFMI
EECCEEEEEEECCCCCHHHHHCCCCCCCCCCCEEEECCCCEEEEECCCCCCCCCEEEEEE
ESQIHYVADAIAKCDRMGVQALAPTREAQDRFNQELQRRLAGSVWNSGGCRSWYLDEHGK
ECHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCC
NTVLWCGYTWQYWLTTRSVNPAEYRFFGIGNGLSSDRATVAAAN
CEEEEEECEEEEEEEECCCCCCCEEEEECCCCCCCCCCEEEECC
>Mature Secondary Structure 
SIADTAAKPSTPSPANQPPVRTRAVIIGTGFSGLGMAIALQKQGVDFVILEKADDVGGT
CCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCEEEEEECCCCCEEEEECCCCCCCC
WRDNTYPGCACDIPSHLYSFSFEPKADWKHLFSYWDEILGYLKGVTDKYGLRRYIEFNSL
CCCCCCCCEEECCCHHHHEECCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
VDRGYWDDDECRWHVFTADGREYVAQFLISGAGALHIPSFPEIAGRDEFAGPAFHSAQWD
HHCCCCCCCCCEEEEEECCCHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCCCCCCCC
HSIDLTGKRVAIVGTGASAIQIVPEIVGQVAELQLYQRTPPWVVPRTNEELPVSLRRALR
CEECCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHEECCCCEEECCCCCCCCHHHHHHHH
TVPGLRALLRLGIYWAQEALAYGMTKRPNTLKIIEAYAKYNIRRSVKDRELRRKLTPRYR
HCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
IGCKRILNSSTYYPAVADPKTELITDRIDRITHDGIVTADGTGREVFREADVIVYATGFH
HHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEECCCCHHHHHCCCEEEEEECEE
VTDSYTYVQIKGRHGEDLVDRWNREGIGAHRGITVANMPNLFFLLGPNTGLGHNSVVFMI
EECCEEEEEEECCCCCHHHHHCCCCCCCCCCCEEEECCCCEEEEECCCCCCCCCEEEEEE
ESQIHYVADAIAKCDRMGVQALAPTREAQDRFNQELQRRLAGSVWNSGGCRSWYLDEHGK
ECHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCC
NTVLWCGYTWQYWLTTRSVNPAEYRFFGIGNGLSSDRATVAAAN
CEEEEEECEEEEEEEECCCCCCCEEEEECCCCCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]