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The map label for this gene is paaJ [C]

Identifier: 148823978

GI number: 148823978

Start: 3110919

End: 3112124

Strand: Reverse

Name: paaJ [C]

Synonym: TBFG_12803

Alternate gene names: 148823978

Gene position: 3112124-3110919 (Counterclockwise)

Preceding gene: 148823979

Following gene: 148823977

Centisome position: 70.34

GC content: 64.18

Gene sequence:

>1206_bases
ATGCCTAACCAAGGGTCGTCGAACAAGGTTTACGTCATTGGCGTGGGCATGACGAAGTTCGAAAAGCCCGGGCGACGCGA
AGGCTGGGACTACCCGGACATGGCCAGGGAGTCGGGCACCAAAGCGCTGCGCGACGCCGGCATCGACTACCGCGAAGTTG
AACAGGGCTACGTCGGCTACGTCTACGGAGAATCGACGTCGGGTCAGCGGGCGCTCTACGAACTCGGCATGACGGGTATC
CCCATCGTCAACGTCAACAACAACTGCTCGACCGGATCCACGGCGCTCTACCTCGGCGCGCAGGCCATCCGCGGCGGACT
GGCCGATTGCGTGTTGGCGCTGGGCTTCGAGAAGATGCAGCCCGGAGCGCTGGGCGGTGGCGCCGACGACCGGGAGTCGC
CGCTGGGCAGGCACGTCAAGGCGTTAGCCGAGATCGACGAGTTCGGCTTTCCGGTGGCGCCGTGGATGTTCGGGGCGGCC
GGCCGCGAACACATGAAGAAATACGGCACCACCGCGGAGCATTTCGCGAAGATCGGCTACAAGAACCACAAGCACTCGGT
CAACAACCCGTATGCACAGTTTCAGGACGAATACACCCTGGACGACATCTTGGCCTCAAAGATGATTTCCGACCCGCTGA
CCAAATTGCAGTGCTCTCCCACCTCCGACGGGTCGGCGGCGGTGGTGCTGGCCAGTGAGGATTACCTGGCCAACCACAAC
CTTGCCGGGCGGGCTGTGGAAATCGTCGGGCAGGCGATGACCACCGACTTCGCTTCCACCTTTGATGGCAGTGCCCGCAA
TATCATCGGCTACGACATGACTGTGCAAGCGGCACAACGGGTTTACCAGCAATCCGGACTCGGCCCGAAGGACTTCGGAG
TGATCGAGCTGCACGACTGCTTCTCAGCCAACGAGCTACTGCTCTACGAGGCGCTCGGCCTGTGCGGGCCGGGCGAGGCG
CCCGAGCTGATCGACGACAACCAGACCACCTACGGCGGACGCTGGGTCGTCAACCCATCCGGTGGGCTGATCTCCAAGGG
CCATCCGCTGGGTGCGACGGGGTTGGCGCAGTGCGCGGAGCTGACCTGGCAGCTGCGCGGCACCGCCGAGGCGCGCCAGG
TCGACAACGTGACCGCCGCGCTGCAACACAACATCGGGCTGGGCGGCGCCGCCGTGGTCACCGCATACCAACGGGCCGAA
CGTTGA

Upstream 100 bases:

>100_bases
GTGAAGCGCGGAAGGGAAGCAGCCGCAAGGCTGCCGAACAACCCCGAGACGGGGTGCAAGTCGCGTGACCACTAAAGATC
ACTCACTTGCAACGGCAACG

Downstream 100 bases:

>100_bases
GCCACGCGATCGGAGGGAGCACGCCATGTTCGAGTGGTCCGACACCGATCTAATGGTGCGCGACGCCGTTCGCCAGTTCA
TCGACAAGGAGATCCGCCCG

Product: lipid-transfer protein

Products: CoA; 3-oxoacyl-CoA

Alternate protein names: NA

Number of amino acids: Translated: 401; Mature: 400

Protein sequence:

>401_residues
MPNQGSSNKVYVIGVGMTKFEKPGRREGWDYPDMARESGTKALRDAGIDYREVEQGYVGYVYGESTSGQRALYELGMTGI
PIVNVNNNCSTGSTALYLGAQAIRGGLADCVLALGFEKMQPGALGGGADDRESPLGRHVKALAEIDEFGFPVAPWMFGAA
GREHMKKYGTTAEHFAKIGYKNHKHSVNNPYAQFQDEYTLDDILASKMISDPLTKLQCSPTSDGSAAVVLASEDYLANHN
LAGRAVEIVGQAMTTDFASTFDGSARNIIGYDMTVQAAQRVYQQSGLGPKDFGVIELHDCFSANELLLYEALGLCGPGEA
PELIDDNQTTYGGRWVVNPSGGLISKGHPLGATGLAQCAELTWQLRGTAEARQVDNVTAALQHNIGLGGAAVVTAYQRAE
R

Sequences:

>Translated_401_residues
MPNQGSSNKVYVIGVGMTKFEKPGRREGWDYPDMARESGTKALRDAGIDYREVEQGYVGYVYGESTSGQRALYELGMTGI
PIVNVNNNCSTGSTALYLGAQAIRGGLADCVLALGFEKMQPGALGGGADDRESPLGRHVKALAEIDEFGFPVAPWMFGAA
GREHMKKYGTTAEHFAKIGYKNHKHSVNNPYAQFQDEYTLDDILASKMISDPLTKLQCSPTSDGSAAVVLASEDYLANHN
LAGRAVEIVGQAMTTDFASTFDGSARNIIGYDMTVQAAQRVYQQSGLGPKDFGVIELHDCFSANELLLYEALGLCGPGEA
PELIDDNQTTYGGRWVVNPSGGLISKGHPLGATGLAQCAELTWQLRGTAEARQVDNVTAALQHNIGLGGAAVVTAYQRAE
R
>Mature_400_residues
PNQGSSNKVYVIGVGMTKFEKPGRREGWDYPDMARESGTKALRDAGIDYREVEQGYVGYVYGESTSGQRALYELGMTGIP
IVNVNNNCSTGSTALYLGAQAIRGGLADCVLALGFEKMQPGALGGGADDRESPLGRHVKALAEIDEFGFPVAPWMFGAAG
REHMKKYGTTAEHFAKIGYKNHKHSVNNPYAQFQDEYTLDDILASKMISDPLTKLQCSPTSDGSAAVVLASEDYLANHNL
AGRAVEIVGQAMTTDFASTFDGSARNIIGYDMTVQAAQRVYQQSGLGPKDFGVIELHDCFSANELLLYEALGLCGPGEAP
ELIDDNQTTYGGRWVVNPSGGLISKGHPLGATGLAQCAELTWQLRGTAEARQVDNVTAALQHNIGLGGAAVVTAYQRAER

Specific function: Thiolytic Cleavage Of Beta-Ketoadipyl-CoA To Succinate And Acetyl-CoA (By Similarity). [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI19923233, Length=394, Percent_Identity=62.4365482233503, Blast_Score=496, Evalue=1e-140,
Organism=Homo sapiens, GI302344760, Length=394, Percent_Identity=58.8832487309645, Blast_Score=457, Evalue=1e-128,
Organism=Homo sapiens, GI302344767, Length=325, Percent_Identity=62.7692307692308, Blast_Score=414, Evalue=1e-116,
Organism=Homo sapiens, GI302344762, Length=393, Percent_Identity=54.70737913486, Blast_Score=412, Evalue=1e-115,
Organism=Homo sapiens, GI55956775, Length=355, Percent_Identity=52.6760563380282, Blast_Score=353, Evalue=1e-97,
Organism=Escherichia coli, GI1787663, Length=309, Percent_Identity=27.831715210356, Blast_Score=71, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17537653, Length=384, Percent_Identity=52.34375, Blast_Score=412, Evalue=1e-115,
Organism=Drosophila melanogaster, GI24585051, Length=395, Percent_Identity=64.3037974683544, Blast_Score=517, Evalue=1e-147,
Organism=Drosophila melanogaster, GI19921506, Length=395, Percent_Identity=63.2911392405063, Blast_Score=514, Evalue=1e-146,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002155
- InterPro:   IPR016039
- InterPro:   IPR016038
- InterPro:   IPR020617
- InterPro:   IPR020616 [H]

Pfam domain/function: PF02803 Thiolase_C; PF00108 Thiolase_N [H]

EC number: 2.3.1.16

Molecular weight: Translated: 42904; Mature: 42773

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: PS00098 THIOLASE_1 ; PS00737 THIOLASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNQGSSNKVYVIGVGMTKFEKPGRREGWDYPDMARESGTKALRDAGIDYREVEQGYVGY
CCCCCCCCEEEEEEECHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHCCCCEEE
VYGESTSGQRALYELGMTGIPIVNVNNNCSTGSTALYLGAQAIRGGLADCVLALGFEKMQ
EECCCCCCHHHHHHCCCCCCEEEECCCCCCCCCEEEEECHHHHHCHHHHHHHHHCHHHCC
PGALGGGADDRESPLGRHVKALAEIDEFGFPVAPWMFGAAGREHMKKYGTTAEHFAKIGY
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHCCCHHHHHHHCC
KNHKHSVNNPYAQFQDEYTLDDILASKMISDPLTKLQCSPTSDGSAAVVLASEDYLANHN
CCCCCCCCCCHHHHCCCCCHHHHHHHHHHHCCHHHEECCCCCCCCEEEEEECCCHHCCCC
LAGRAVEIVGQAMTTDFASTFDGSARNIIGYDMTVQAAQRVYQQSGLGPKDFGVIELHDC
CCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHCCCCCCCCCEEEECCC
FSANELLLYEALGLCGPGEAPELIDDNQTTYGGRWVVNPSGGLISKGHPLGATGLAQCAE
CCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHH
LTWQLRGTAEARQVDNVTAALQHNIGLGGAAVVTAYQRAER
HHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
PNQGSSNKVYVIGVGMTKFEKPGRREGWDYPDMARESGTKALRDAGIDYREVEQGYVGY
CCCCCCCEEEEEEECHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHCCCCEEE
VYGESTSGQRALYELGMTGIPIVNVNNNCSTGSTALYLGAQAIRGGLADCVLALGFEKMQ
EECCCCCCHHHHHHCCCCCCEEEECCCCCCCCCEEEEECHHHHHCHHHHHHHHHCHHHCC
PGALGGGADDRESPLGRHVKALAEIDEFGFPVAPWMFGAAGREHMKKYGTTAEHFAKIGY
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHCCCHHHHHHHCC
KNHKHSVNNPYAQFQDEYTLDDILASKMISDPLTKLQCSPTSDGSAAVVLASEDYLANHN
CCCCCCCCCCHHHHCCCCCHHHHHHHHHHHCCHHHEECCCCCCCCEEEEEECCCHHCCCC
LAGRAVEIVGQAMTTDFASTFDGSARNIIGYDMTVQAAQRVYQQSGLGPKDFGVIELHDC
CCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHCCCCCCCCCEEEECCC
FSANELLLYEALGLCGPGEAPELIDDNQTTYGGRWVVNPSGGLISKGHPLGATGLAQCAE
CCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHH
LTWQLRGTAEARQVDNVTAALQHNIGLGGAAVVTAYQRAER
HHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acetyl-CoA

Specific reaction: acyl-CoA + acetyl-CoA = CoA + 3-oxoacyl-CoA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]